Other chronic figurate erythema

L12_ERYTH_CHRONICFIG

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L53.3 Cause of death: ICD-10 — L53.3 2 out of 7 registries used, show all original rules.	18
4. Check minimum number of events None	18
5. Include endpoints None	18
6. Filter based on genotype QC (FinnGen only)	18

Control definitions (FinnGen only)

Control exclude: L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L53
Name in latin: Erythema figuratum chronicum

NAME	L12_ERYTH_CHRONICFIG
CONTROL_EXCLUDE	L12_URTICARIAERYTHEMA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L533
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L533
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other chronic figurate erythema based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	98	62	35
Only index persons	91	59	32
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	55.61	58.63	51.11
Only index persons	56.64	58.07	54.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	18	13	5
Unadjusted period prevalence (%)	0.00	0.00	0.00
Median age at first event (years)	59.92	59.19	61.79

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768443) Skin Pathology biopsy report

10.87

2.94

1.4

1.2

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

4.78

2.64

1.7

1.4

1.2

1.3

mmol/l

—

(3007853) Bacteria identified in Skin by Aerobe culture

7.17

2.38

1.4

1.3

—

(3000494) Fungus identified in Specimen by Culture

5.42

2.25

1.5

—

(3002256) Pathology report gross observation

3.65

1.46

1.0

1.2

—

(40758558) Short blood count panel - Blood

3.07

1.46

8.0

9.5

—

(42870588) Differential panel, method unspecified - Blood

3.07

1.46

17.6

5.8

—

(3009508) Creatinine [Moles/volume] in Urine

2.92

1.26

3.3

1.9

6.1

7.3

mmol/l

—

(3042936) Bacteria identified in Isolate by Culture

2.89

1.17

2.0

1.8

—

(3023368) Bacteria identified in Blood by Culture

2.39

0.95

2.2

5.7

—

(40768804) Tissue Pathology biopsy report

2.26

0.94

2.6

2.0

—

(3033658) Prothrombin time (PT) actual/Normal

2.08

0.72

14.6

4.4

75.0

88.0

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

2.08

0.72

3.8

3.9

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

1.91

0.72

7.6

2.7

35.4

29.6

u/l

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

2.04

0.66

4.7

3.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.64

0.0

1.6

—

(3015736) pH of Urine

1.81

0.54

2.9

3.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.92

0.49

1.0

1.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.00

0.43

0.0

1.7

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.00

0.43

0.0

2.1

—

(3044640) Blood type and Crossmatch panel - Blood

1.64

0.41

1.7

2.3

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

1.48

0.36

2.3

2.0

70.9

72.0

nmol/l

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

100

0.64

0.34

4.8

2.5

81.3

43.5

u/l

—

(3044889) 12 lead EKG panel

1.47

0.33

5.1

3.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

1.37

0.24

4.5

2.7

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

1.37

0.22

3.0

2.7

131.4

62.1

ug/l

—

(3000330) Specific gravity of Urine by Test strip

0.00

0.22

0.0

2.9

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

0.22

0.0

1.4

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

0.00

0.22

0.0

1.5

—

19.6

—

(3019225) pH of Specimen

0.00

0.22

0.0

2.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

1.18

0.10

2.4

3.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

0.82

0.09

6.1

4.1

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

0.0

1.2

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.0

2.8

—

7.1

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.0

1.0

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.0

1.4

—

(3013707) Erythrocyte sedimentation rate by Westergren method

110

1.00

0.00

13.0

4.1

13.5

11.3

mm/h

0.25

101

(3028300) Cannabinoids [Presence] in Urine

0.00

0.0

1.3

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

66.4

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.0

1.3

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

1.7

—

112.9

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

0.00

0.0

3.0

—

5.0

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.4

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

0.0

1.4

—

(4094501)

0.00

0.0

1.1

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.0

1.3

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

0.00

0.0

3.0

—

1.2

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3016879) Cocaine [Presence] in Urine

0.00

0.0

1.3

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

0.00

0.0

1.3

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

0.0

2.8

—

24.0

—

(1002224) Polysomnography panel

0.00

0.0

1.3

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.0

3.4

—

30.7

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

0.85

0.00

3.8

4.9

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

0.00

0.0

4.8

—

24.3

—

(3018405) Lactate [Moles/volume] in Arterial blood

0.00

0.0

2.8

—

0.9

—

(3027008) Opiates [Presence] in Urine

0.00

0.0

1.3

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.4

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.2

—

(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

55.0

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

0.00

0.0

1.6

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.6

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

1.05

0.00

4.4

3.9

6.3

6.4

mmol/l

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.0

2.8

—

1.3

—

(3019060) Gas panel - Arterial blood

0.00

0.0

2.8

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_ERYTH_CHRONICFIG and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_ERYTH_CHRONICFIG.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_ERYTH_CHRONICFIG – Other chronic figurate erythema

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other chronic figurate erythema

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints