This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Toxic myoneural disorders
G6_TOXMYONEU
Myasthenia gravis: Myasthenia gravis (MG) is a rare, clinically heterogeneous, autoimmune disorder of the neuromuscular junction characterized by fatigable weakness of voluntary muscles.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
18 |
4. Check minimum number of eventsNone |
18 |
5. Include endpointsNone |
18 |
6. Filter based on genotype QC (FinnGen only) |
18 |
Control definitions (FinnGen only)
- Control exclude
- G6_MYONEU
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G70
- Name in latin
- Morbositates myoneurales toxicae
Similar endpoints
↥List of similar endpoints to
Toxic myoneural disorders
based on the number of shared cases.
Similar with more cases:
- Diseases of the myoneural junction and muscle
- Neurological diseases
- Neurological diseases, wide definition
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 149 | 85 | 63 |
| Only index persons | 128 | 73 | 55 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 58.80 | 58.36 | 59.58 |
| Only index persons | 57.32 | 58.36 | 55.94 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 18 | 13 | 5 |
| Unadjusted period prevalence (%) | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | 54.43 | 53.85 | 55.94 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
5
6
10.87
2.94
1.0
1.0
—
—
—
0
0
8
26
4.69
2.38
2.8
2.3
—
—
—
0
0
5
13
4.88
1.85
2.4
1.8
—
—
—
0
0
12
80
2.49
1.07
8.1
4.8
0.00
0.00
estimate
—
5
17
12
82
2.38
0.87
8.6
4.8
0.00
0.00
estimate
—
5
15
0
23
0.00
0.86
0.0
5.8
—
—
—
0
0
13
95
2.32
0.85
3.6
2.4
—
—
—
0
0
9
60
1.99
0.71
10.0
2.8
—
—
—
0
0
11
79
2.00
0.67
11.5
7.4
0.00
0.00
estimate
—
5
16
7
49
1.70
0.54
2.7
4.3
1940.71
939.23
ng/l
—
7
41
5
70
0.61
0.35
2.8
4.0
—
—
—
0
0
0
14
0.00
0.21
0.0
2.5
—
—
—
0
0
10
92
1.19
0.09
7.8
3.9
6.16
6.68
mmol/l
—
10
85
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
3.3
—
41.81
—
0
8
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
6
64
0.91
0.00
9.8
4.8
—
—
—
0
0
13
128
1.06
0.00
32.5
17.2
13.85
13.87
%
0.02
13
121
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_TOXMYONEU and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have G6_TOXMYONEU.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: G6_TOXMYONEU – Toxic myoneural disorders
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
-
5 (0.01)
-
-
-
-
-
0 (0.00)
-
-
9
-
-
0 (0.00)
-
-
2
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
-
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
3
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
5 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
-
-
-
116
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
0 (0.00)
-
-
2
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
3
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
9 (0.01)
-
-
-
-
-
6 (0.01)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
2
-
-
0 (0.00)
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
25
-
-
-
-
-
1
-
-
0 (0.00)
-
-
23
-
-
0 (0.00)
-
-
29
-
-
-
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
12
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
4
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
5 (0.01)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
66
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
Neuroendocrine tumor and carcinoma of rectum, excluding all cancers (controls excluding all cancers)
-
-
-
-
-
-
-
-
-
-
13
-
-
-
-
-
1
-
-
0 (0.00)
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
7 (0.01)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
4
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
9
-
-
-
-
-
100
-
-
-
-
-
18
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
3
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
2
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
3
-
-
-
-
-
-
-
-
0 (0.00)
-
-
7
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
2
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
2
-
-
0 (0.00)
-
-
-
-
-
6 (0.01)
-
-
-
-
-
0 (0.00)
-
-
17
-
-
0 (0.00)
-
-
11
-
-
-
-
-
-
-
-
0 (0.00)
-
-
18
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
Mucinous and mucinous cystic tumor of rectum, excluding all cancers (controls excluding all cancers)
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
3
-
-
-
-
-
16
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
10
-
-
0 (0.00)
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
4
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
2
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
2
-
Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
86
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
2
-
-
0 (0.00)
-
-
14
-
-
-
-
-
-
-
9 (0.01)
0 (0.00)
-
-
6
-
5 (0.00)
-
-
-
3
-
11 (0.01)
0 (0.00)
-
-
1
-
11 (0.01)
-
-
-
-
-
10 (0.01)
-
-
-
2
-
22 (0.01)
5 (0.02)
-
-
1
-
7 (0.00)
-
-
-
57
-
8 (0.00)
-
-
-
2
-
28 (0.00)
5 (0.01)
-
-
193
-