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This is a non-core endpoint: only basic statistics are computed.

Papulosquamous disorders in diseases classified elsewhere

L12_PAPULOSQUOINOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L45*
  • Cause of death: ICD-10 L45*

2 out of 7 registries used, show all original rules.

8

4. Check minimum number of events

None

8

5. Include endpoints

None

8

6. Filter based on genotype QC (FinnGen only)

8

Control definitions (FinnGen only)

Control exclude
L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 67 29 38
Only index persons 61 28 33
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population - 46.98 51.07
Only index persons 50.70 48.11 52.91

-FinnGen-

Key figures

All Female Male
Number of individuals 8 5 -
Unadjusted period prevalence (%) 0.00 0.00 -
Median age at first event (years) 49.05 49.24 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3013650) Neutrophils [#/volume] in Blood by Automated count
8
42
+∞
2.04
28.0
15.4
e9/l
4.0
4.9
—
8
37
(3013707) Erythrocyte sedimentation rate by Westergren method
8
47
+∞
1.64
21.4
4.3
mm/h
22.9
11.3
—
8
39
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
8
59
+∞
0.72
45.6
9.5
u/l
109.1
88.1
—
8
54
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
8
69
+∞
0.23
4.1
4.5
mmol/l
5.5
6.0
—
8
61
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
8
67
+∞
0.22
5.4
4.7
mu/l
1.5
2.0
—
8
55
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(1002224) Polysomnography panel
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
8
71
+∞
0.00
84.6
13.9
mg/l
21.1
24.8
—
8
45
(40761536) Microorganisms panel - Urine sediment
0
7
0.00
0.00
0.0
3.9
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3023323) Follitropin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
35.7
—
0
5
(3000492) Spirometry study
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_PAPULOSQUOINOTH and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_PAPULOSQUOINOTH.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: L12_PAPULOSQUOINOTH – Papulosquamous disorders in diseases classified elsewhere

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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