This is a non-core endpoint: only basic statistics are computed.

Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere

L12_SKININOTHNAS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L99.8, L99.8A50.0, L99.8A51.3, L99.8A52.79 Cause of death: ICD-10 — L99.8, L99.8A50.0, L99.8A51.3, L99.8A52.79 2 out of 7 registries used, show all original rules.	12
4. Check minimum number of events None	12
5. Include endpoints None	12
6. Filter based on genotype QC (FinnGen only)	12

Control definitions (FinnGen only)

Control exclude: L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2

NAME	L12_SKININOTHNAS
CONTROL_EXCLUDE	L12_OTHERSKINSUBCUTIS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L998
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L998
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	96	39	57
Only index persons	85	37	48
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	51.71	45.95
Only index persons	48.21	51.71	45.50

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	12	-	8
Unadjusted period prevalence (%)	0.00	-	0.00
Median age at first event (years)	51.49	-	56.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3017143) Hepatitis C virus Ab [Presence] in Serum

7.38

2.53

5.3

2.5

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

4.64

1.78

7.3

2.3

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

4.26

1.53

1.8

2.1

24.8

28.7

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

3.53

1.30

5.4

1.8

—

(40758558) Short blood count panel - Blood

3.11

1.09

9.7

6.6

—

(3044640) Blood type and Crossmatch panel - Blood

2.56

0.82

5.8

2.3

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

2.32

0.71

8.8

2.7

—

(36304419) Bacteria [Presence] in Urine

2.13

0.52

3.8

2.7

—

(3033658) Prothrombin time (PT) actual/Normal

2.13

0.52

3.4

3.5

105.0

90.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

2.04

0.51

11.2

3.6

—

(40768804) Tissue Pathology biopsy report

2.04

0.51

3.6

1.9

—

(3018418) pH of Serum or Plasma

2.04

0.51

19.2

3.6

—

7.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

2.06

0.47

8.0

3.6

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

0.00

0.45

0.0

1.0

—

0.8

—

(3044889) 12 lead EKG panel

0.53

0.44

4.6

3.6

—

(3031040) Bacteria [#/volume] in Urine by Automated count

1.76

0.42

6.9

3.8

—

(3002582) Erythrocytes [#/volume] in Urine

1.73

0.29

3.0

2.7

8.8

78.6

e6/l

—

(42870588) Differential panel, method unspecified - Blood

1.66

0.29

9.8

7.5

—

(3000492) Spirometry study

0.00

0.22

0.0

1.5

—

(4010399)

0.00

0.22

0.0

1.4

—

(3022145) Colonoscopy Study observation

0.00

0.22

0.0

1.4

—

(40768797) Stomach Pathology biopsy report

0.00

0.22

0.0

1.2

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.0

3.8

—

4.9

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.0

3.8

—

9.8

—

(3010421) pH of Blood

0.00

0.0

4.0

—

7.4

—

(3003327) Ova and parasites identified in Stool by Light microscopy

0.00

0.0

1.2

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

1.2

—

(36660697) Celiac disease serology panel - Serum

0.00

0.0

1.1

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.00

0.0

1.3

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.0

1.2

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.0

1.7

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

0.97

0.00

3.5

2.5

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

(4034850)

0.00

0.0

5.8

—

(1616796) Gas panel - Central venous blood

0.00

0.0

5.2

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.8

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

0.8

—

(3016879) Cocaine [Presence] in Urine

0.00

0.0

1.0

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.0

—

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.0

2.3

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.8

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

0.00

0.0

1.7

—

(40761536) Microorganisms panel - Urine sediment

0.00

0.0

3.4

—

(3049717) Cytology report of Urine Cyto stain

0.00

0.0

4.8

—

(3022621) pH of Urine by Test strip

0.00

0.0

2.2

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.3

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.2

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

0.00

0.0

7.3

—

1.2

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

0.3

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.0

1.0

—

(3027008) Opiates [Presence] in Urine

0.00

0.0

1.0

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.0

1.0

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.0

1.6

—

1.3

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_SKININOTHNAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_SKININOTHNAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_SKININOTHNAS – Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints