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Omphalitis of newborn with or without mild haemorrhage

P16_OMPHA_NEWBO_W_WO_MILD_HAEMORRHAGE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P38
  • Cause of death: ICD-10 P38

2 out of 7 registries used, show all original rules.

7

4. Check minimum number of events

None

7

5. Include endpoints

None

7

6. Filter based on genotype QC (FinnGen only)

7

Control definitions (FinnGen only)

Control exclude
P16_INFECTIONS_SPECIFIC_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P3
Name in latin
Omphalitis neonatalis cum/sine haemorrhagia levi

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 677 296 381
Only index persons 339 154 185
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population - 0.03 0.03
Only index persons 0.03 0.04 0.03

-FinnGen-

Key figures

All Female Male
Number of individuals 7 - 5
Unadjusted period prevalence (%) 0.00 - 0.00
Median age at first event (years) 0.36 - 0.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
0
26
0.00
1.05
0.0
1.6
—
1.3
—
0
13
0
14
0.00
0.47
0.0
1.8
—
—
—
0
0
0
14
0.00
0.47
0.0
1.7
—
—
—
0
0
0
11
0.00
0.23
0.0
1.9
—
—
—
0
0
0
11
0.00
0.23
0.0
1.9
—
—
—
0
0
0
11
0.00
0.23
0.0
1.9
—
—
—
0
0
0
11
0.00
0.23
0.0
1.3
—
—
—
0
0
0
11
0.00
0.23
0.0
4.0
—
—
—
0
0
0
11
0.00
0.23
0.0
2.0
—
—
—
0
0
0
11
0.00
0.23
0.0
1.9
—
—
—
0
0
0
10
0.00
0.23
0.0
1.7
—
—
—
0
0
0
12
0.00
0.23
0.0
2.2
—
—
—
0
0
0
9
0.00
0.23
0.0
1.3
—
—
—
0
0
0
9
0.00
0.23
0.0
3.1
—
—
—
0
0
0
13
0.00
0.23
0.0
1.4
—
—
—
0
0
0
13
0.00
0.23
0.0
1.3
—
2.4
—
0
13
0
8
0.00
0.00
0.0
1.0
—
2.9
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
35.7
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
606.2
—
0
6
0
5
0.00
0.00
0.0
3.2
—
0.8
—
0
5
0
7
0.00
0.00
0.0
2.9
—
3.2
—
0
7
0
7
0.00
0.00
0.0
3.0
—
12.9
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
3.8
—
7.0
—
0
5
0
5
0.00
0.00
0.0
2.6
—
2.5
—
0
5
0
5
0.00
0.00
0.0
2.4
—
17.9
—
0
5
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_OMPHA_NEWBO_W_WO_MILD_HAEMORRHAGE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_OMPHA_NEWBO_W_WO_MILD_HAEMORRHAGE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_OMPHA_NEWBO_W_WO_MILD_HAEMORRHAGE – Omphalitis of newborn with or without mild haemorrhage

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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