This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

AB1_RICKETTSIOSES

Q fever

EFO Endpoint Browser

AB1_Q_FEVER

No definition available.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — A78 Cause of death: ICD-10 — A78 2 out of 7 registries used, show all original rules.	14
4. Check minimum number of events None	14
5. Include endpoints None	14
6. Filter based on genotype QC (FinnGen only)	14

Control definitions (FinnGen only)

Control exclude: AB1_RICKETTSIOSES

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF5

NAME	AB1_Q_FEVER
CONTROL_EXCLUDE	AB1_RICKETTSIOSES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	A78
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	A78
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Q fever based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	79	21	58
Only index persons	73	19	54
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	52.02	54.22
Only index persons	53.31	54.72	52.81

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	14	-	11
Unadjusted period prevalence (%)	0.00	-	0.00
Median age at first event (years)	59.43	-	63.23

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(3019768) Coxiella burnetii Ab [Presence] in Serum

+∞

5.53

4.6

0.0

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

11.65

4.07

8.1

4.9

mmol/l

104.3

102.6

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

10.23

2.79

4.0

33.6

39.4

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

8.91

2.60

3.4

7.9

mmol/l

26.3

23.8

—

(3000991) Gas panel - Venous blood

8.91

2.60

13.2

6.9

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

8.91

2.60

3.6

8.5

g/l

135.4

140.1

—

(3012544) pH of Venous blood

7.17

2.59

5.8

5.9

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

5.90

2.46

1.4

1.5

—

(3042936) Bacteria identified in Isolate by Culture

4.19

1.73

2.5

1.7

—

(3023368) Bacteria identified in Blood by Culture

3.54

1.52

11.6

3.8

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

3.97

1.50

1.2

u/ml

1.3

11.1

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

3.59

1.50

2.0

1.8

29.3

29.4

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

3.30

1.44

3.3

2.7

ng/l

871.0

981.0

—

(40758558) Short blood count panel - Blood

2.51

0.95

13.2

5.3

—

(36304419) Bacteria [Presence] in Urine

2.76

0.94

8.4

2.6

—

(3044640) Blood type and Crossmatch panel - Blood

2.76

0.94

3.4

2.8

—

(1761868) Lipid panel - Serum or Plasma

2.76

0.94

3.6

3.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

2.40

0.87

2.1

3.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

2.21

0.74

2.4

2.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

2.07

0.58

4.0

2.5

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.94

0.50

2.2

2.6

—

(40761511) CBC panel - Blood by Automated count

125

+∞

0.44

23.6

17.6

—

(40761536) Microorganisms panel - Urine sediment

0.00

0.44

0.0

3.9

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

0.00

0.43

0.0

1.2

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.00

0.43

0.0

5.5

—

28.3

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

1.63

0.42

3.2

2.6

nmol/l

92.7

74.8

—

(3031040) Bacteria [#/volume] in Urine by Automated count

1.65

0.38

6.2

3.5

—

(3013512) EKG study

1.44

0.26

6.8

4.4

—

(42870588) Differential panel, method unspecified - Blood

1.53

0.26

7.7

5.0

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

1.45

0.24

6.3

4.0

ng/l

19.6

26.7

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

129

+∞

0.22

47.1

18.1

umol/l

179.5

91.8

0.59

129

(21494755) Public health laboratory ask at order entry panel

0.00

0.22

0.0

1.5

—

(4035726)

0.00

0.22

0.0

1.3

—

(36660697) Celiac disease serology panel - Serum

0.00

0.22

0.0

1.3

—

(3019225) pH of Specimen

0.00

0.22

0.0

4.9

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

1.29

0.12

2.4

3.6

u/l

53.0

61.1

—

(40768804) Tissue Pathology biopsy report

1.25

0.12

2.8

1.7

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

1.27

0.11

3.8

3.0

ug/l

286.6

168.8

—

(3025941) Bacteria identified in Stool by Culture

0.00

0.0

1.1

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.00

0.0

1.4

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

0.00

0.0

2.1

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.2

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

3.8

—

(1616796) Gas panel - Central venous blood

0.00

0.0

4.4

—

(3020961) Endomysium IgA Ab [Titer] in Serum

0.00

0.0

1.2

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.0

5.3

—

4.8

—

(3028626) Oxygen [Partial pressure] in Capillary blood

0.00

0.0

3.8

—

8.5

—

(3013707) Erythrocyte sedimentation rate by Westergren method

1.10

0.00

10.2

4.1

mm/h

7.8

12.8

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

0.0

3.0

—

(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma

0.00

0.0

1.8

—

12.3

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.0

5.3

—

8.4

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.0

2.0

—

(3010421) pH of Blood

0.00

0.0

5.5

—

7.4

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.0

—

(4034850)

0.00

0.0

9.7

—

(3047181) Lactate [Moles/volume] in Blood

0.00

0.0

10.4

—

0.9

—

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_Q_FEVER and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_Q_FEVER.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: AB1_Q_FEVER – Q fever

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Q fever

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints