This is a non-core endpoint: only basic statistics are computed.

Disorders of glycoprotein metabolism, other/unspecified

E4_GLYCOPROTNAS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — E77.8, E77.9 Cause of death: ICD-10 — E77.8, E77.9 2 out of 7 registries used, show all original rules.	13
4. Check minimum number of events None	13
5. Include endpoints None	13
6. Filter based on genotype QC (FinnGen only)	13

Control definitions (FinnGen only)

Control exclude: E4_METABOLIA

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2

NAME	E4_GLYCOPROTNAS
CONTROL_EXCLUDE	E4_METABOLIA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E77[8-9]
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E77[8-9]
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Disorders of glycoprotein metabolism, other/unspecified based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	98	50	48
Only index persons	87	44	43
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	53.21	53.76
Only index persons	53.49	52.39	54.62

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	13	6	7
Unadjusted period prevalence (%)	0.00	0.00	0.00
Median age at first event (years)	56.06	52.39	59.21

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(40760892) CBC W Ordered Manual Differential panel - Blood

5.34

2.20

10.4

4.8

—

(3020682) Albumin/Creatinine [Ratio] in Urine

5.07

2.11

5.3

3.2

mg/mmol

2.4

0.7

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

4.64

2.00

6.1

2.9

—

(3012516) Albumin [Mass/volume] in Urine

3.94

1.59

4.3

2.5

mg/l

36.9

6.8

—

(1761868) Lipid panel - Serum or Plasma

3.83

1.57

5.5

2.2

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

+∞

1.41

13.2

4.2

mmol/mol

47.5

38.3

1.45

(3015736) pH of Urine

3.44

1.21

4.1

3.0

—

(36304419) Bacteria [Presence] in Urine

3.24

1.12

3.5

1.9

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

2.51

0.89

4.9

3.5

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

107

+∞

0.89

5.3

4.1

mmol/l

1.3

1.5

1.63

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

107

+∞

0.89

5.8

4.1

mmol/l

4.9

0.07

(3022096) Basophils/100 leukocytes in Blood

2.80

0.88

7.0

6.8

0.9

0.7

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

109

+∞

0.67

6.6

4.4

mmol/l

3.0

2.8

0.24

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

2.27

0.65

21.1

6.0

mmol/l

1.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.83

0.48

5.2

2.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.00

0.44

0.0

1.4

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

116

+∞

0.44

30.0

14.3

umol/l

102.2

75.2

0.49

116

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

1.67

0.42

7.5

4.5

ug/l

26.1

2.0

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

1.92

0.42

5.3

4.7

—

(42870588) Differential panel, method unspecified - Blood

1.40

0.26

6.2

7.1

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.22

0.0

1.1

—

(21494755) Public health laboratory ask at order entry panel

0.00

0.22

0.0

1.5

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

117

+∞

0.22

20.1

10.7

u/l

36.8

26.2

1.01

112

(3044640) Blood type and Crossmatch panel - Blood

1.35

0.12

2.8

2.4

—

(3044889) 12 lead EKG panel

0.85

0.11

3.1

3.9

—

(3013707) Erythrocyte sedimentation rate by Westergren method

0.78

0.11

10.4

4.7

mm/h

9.3

10.7

—

(40768443) Skin Pathology biopsy report

0.00

0.0

1.0

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.00

0.0

1.7

—

(3000492) Spirometry study

0.00

0.0

1.8

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

0.00

0.0

6.7

—

(3020961) Endomysium IgA Ab [Titer] in Serum

0.00

0.0

1.3

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

0.4

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3022621) pH of Urine by Test strip

0.00

0.0

1.0

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

0.91

0.00

2.3

2.7

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

0.00

0.0

1.1

—

(3003327) Ova and parasites identified in Stool by Light microscopy

0.00

0.0

1.0

—

(4010399)

0.00

0.0

1.3

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(36660697) Celiac disease serology panel - Serum

0.00

0.0

1.0

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.2

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3025941) Bacteria identified in Stool by Culture

0.00

0.0

1.2

—

(3047181) Lactate [Moles/volume] in Blood

0.00

0.0

5.6

—

1.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint E4_GLYCOPROTNAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_GLYCOPROTNAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: E4_GLYCOPROTNAS – Disorders of glycoprotein metabolism, other/unspecified

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Disorders of glycoprotein metabolism, other/unspecified

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints