This is a non-core endpoint: only basic statistics are computed.

Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere

K11_GALLBILPANINOTH

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — K87* Cause of death: ICD-10 — K87* 2 out of 7 registries used, show all original rules.	15
4. Check minimum number of events None	15
5. Include endpoints None	15
6. Filter based on genotype QC (FinnGen only)	15

Control definitions (FinnGen only)

Control exclude: K11_GALLBILPANC

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2

NAME	K11_GALLBILPANINOTH
CONTROL_EXCLUDE	K11_GALLBILPANC
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	K87
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	K87
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	197	103	94
Only index persons	165	90	75
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	61.79	66.09
Only index persons	60.07	55.08	66.05

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	15	10	5
Unadjusted period prevalence (%)	0.00	0.00	0.00
Median age at first event (years)	62.56	64.42	58.84

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(42870588) Differential panel, method unspecified - Blood

7.26

3.30

12.6

6.2

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

13.97

3.22

3.8

1.0

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

10.15

3.21

2.2

9.2

—

(3019309) Folate [Moles/volume] in Red Blood Cells

5.14

2.39

1.3

2.2

nmol/l

929.9

1163.3

—

(3009508) Creatinine [Moles/volume] in Urine

4.70

2.27

4.2

2.8

mmol/l

6.4

6.6

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

5.49

2.19

2.3

1.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

5.49

2.19

2.3

1.3

—

(3021960) Folate [Moles/volume] in Serum or Plasma

4.53

2.19

1.4

1.5

nmol/l

19.0

22.9

—

(3022145) Colonoscopy Study observation

6.20

2.12

1.0

1.4

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

4.01

1.90

1.8

2.5

mg/l

2.3

1.9

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

3.63

1.61

5.0

4.5

—

(3001604) Monocytes [#/volume] in Blood

3.43

1.54

19.0

7.3

e9/l

0.7

0.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

3.30

1.41

2.3

1.6

—

(3016502) Oxygen saturation in Arterial blood

3.41

1.33

1.8

10.6

96.2

—

(3018418) pH of Serum or Plasma

2.85

1.20

15.9

5.6

—

7.4

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

111

0.40

0.89

52.1

15.2

ml/min/173m2

69.6

73.7

—

(3026008) Bacteria identified in Urine by Culture

2.39

0.88

7.9

4.5

—

(3033658) Prothrombin time (PT) actual/Normal

2.08

0.71

31.0

4.0

77.6

84.6

—

(3026493) Urate [Moles/volume] in Serum or Plasma

1.70

0.46

3.0

3.5

umol/l

372.8

14514.5

—

(4035726)

0.00

0.43

0.0

1.1

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.00

0.43

0.0

9.9

—

(40768804) Tissue Pathology biopsy report

1.65

0.42

1.8

2.3

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

1.71

0.38

28.9

9.8

e9/l

4.0

4.4

—

(3023368) Bacteria identified in Blood by Culture

1.42

0.26

27.6

4.7

—

(3013707) Erythrocyte sedimentation rate by Westergren method

1.57

0.23

4.0

3.7

mm/h

16.1

14.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

0.66

0.23

9.0

5.3

—

0.0

—

(3000330) Specific gravity of Urine by Test strip

0.00

0.22

0.0

3.8

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.22

0.0

2.4

—

55.8

—

(40761535) Cells panel - Urine sediment

0.00

0.22

0.0

4.3

—

(40761536) Microorganisms panel - Urine sediment

0.00

0.22

0.0

2.5

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

1.37

0.11

3.8

3.5

pmol/l

13.6

15.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

1.17

0.10

2.5

2.4

—

(3035350) Ketones [Presence] in Urine by Test strip

0.87

0.00

6.0

3.7

—

0.0

—

(3018405) Lactate [Moles/volume] in Arterial blood

0.00

0.0

1.9

—

1.2

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.0

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.0

2.1

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

1.6

—

9.6

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

0.00

0.0

1.7

—

0.1

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.0

2.4

—

8.3

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

2.1

—

(3009261) Glucose [Presence] in Urine by Test strip

0.85

0.00

5.8

3.9

—

0.0

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

0.00

0.0

3.8

—

3.9

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

0.00

0.0

1.3

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

0.0

1.9

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.0

1.3

—

52.2

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

2.1

—

4.1

—

(3019225) pH of Specimen

0.00

0.0

5.7

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.0

3.6

—

(3020891) Body temperature

0.00

0.0

2.8

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.00

0.0

1.0

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.5

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.0

2.4

—

1.8

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.0

3.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.00

0.0

1.0

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

2.1

—

106.3

—

Mortality – FinRegistry

↥

Association

Association between endpoint K11_GALLBILPANINOTH and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_GALLBILPANINOTH.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: K11_GALLBILPANINOTH – Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints