This is a non-core endpoint: only basic statistics are computed.
Flexion deformity
M13_FLEXION
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
38 |
4. Check minimum number of eventsNone |
38 |
5. Include endpointsNone |
38 |
6. Filter based on genotype QC (FinnGen only) |
38 |
Control definitions (FinnGen only)
- Control exclude
- M13_ARTHROPATHIES
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M21
- Name in latin
- Deformitas flexionalis
Similar endpoints
↥List of similar endpoints to
Flexion deformity
based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 304 | 195 | 109 |
| Only index persons | 283 | 181 | 102 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | |||
| Whole population | - | 54.39 | 43.13 |
| Only index persons | 49.83 | 53.21 | 43.84 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 38 | 26 | 12 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 55.02 | 53.93 | 57.38 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3000991) Gas panel - Venous blood
8
21
4.53
2.63
3.0
4.2
—
—
—
0
0
(3026782) Osmolality of Urine
14
61
3.05
2.52
2.6
2.5
mosm/kgh2o
629.0
570.3
0.26
14
50
(3044640) Blood type and Crossmatch panel - Blood
17
86
2.77
2.32
1.9
2.4
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
15
77
2.57
1.93
4.1
2.9
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
13
63
2.62
1.86
3.3
4.2
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
28
196
2.63
1.83
4.9
4.2
—
950.5
—
0
6
(40758558) Short blood count panel - Blood
14
73
2.45
1.72
11.6
8.1
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
18
106
2.33
1.69
3.9
3.2
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
6
20
3.36
1.65
2.2
1.3
—
—
—
0
0
(3044889) 12 lead EKG panel
29
217
2.42
1.61
3.9
3.6
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
5
15
3.67
1.57
3.6
3.1
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
18
109
2.24
1.56
4.9
3.8
e6/l
91.3
76.7
0.08
13
71
(40760892) CBC W Ordered Manual Differential panel - Blood
14
76
2.33
1.56
2.5
7.6
—
—
—
0
0
(3012544) pH of Venous blood
7
28
2.83
1.54
2.7
3.1
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
7
29
2.72
1.47
1.6
2.7
ug/g
98.3
73.6
—
7
22
(40768797) Stomach Pathology biopsy report
9
42
2.49
1.46
1.1
1.3
—
—
—
0
0
(3003338) MCHC [Mass/volume]
32
259
2.49
1.37
28.5
17.4
g/l
332.9
333.1
0.06
32
259
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
12
64
2.28
1.37
2.0
2.4
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
6
24
2.77
1.36
3.0
2.0
%
1.6
1.3
—
6
24
(3037467) Urinalysis macro (dipstick) panel - Urine
28
214
2.17
1.24
4.7
4.1
—
—
—
0
0
(3020779) Urea [Moles/volume] in Serum or Plasma
5
21
2.58
1.12
1.8
6.4
mmol/l
7.0
7.9
—
5
21
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
5
22
2.46
1.06
1.0
1.5
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
7
36
2.15
1.03
1.0
1.6
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
18
125
1.84
0.97
3.2
3.8
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
33
286
2.17
0.80
25.0
12.5
%
37.2
39.2
0.58
27
199
(3002256) Pathology report gross observation
7
40
1.92
0.76
1.0
1.2
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
5
28
1.90
0.69
3.8
3.3
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
5
88
0.50
0.66
2.2
3.2
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
29
1.83
0.66
1.4
1.8
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
5
29
1.83
0.66
2.2
1.6
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
22
175
1.61
0.66
5.8
8.5
umol/l
11.5
10.4
0.23
22
165
(3026493) Urate [Moles/volume] in Serum or Plasma
11
73
1.71
0.65
2.6
3.4
umol/l
382.1
13904.6
1.05
11
64
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
6
34
1.90
0.62
3.8
1.5
u/l
34.3
28.0
—
6
25
(3042936) Bacteria identified in Isolate by Culture
6
34
1.90
0.62
1.7
2.1
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
16
119
1.60
0.62
3.5
9.7
inr
1.0
1.3
—
5
36
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
22
178
1.56
0.59
3.8
2.5
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
14
103
1.57
0.56
4.4
2.3
—
—
—
0
0
(3022145) Colonoscopy Study observation
6
40
1.59
0.54
1.0
1.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
15
0.00
0.42
0.0
1.5
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
11
81
1.50
0.42
6.4
3.5
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
9
68
1.42
0.42
1.9
1.5
nmol/l
20.7
20.7
—
9
55
(3001019) Free T4 and TSH panel - Serum or Plasma
0
18
0.00
0.41
0.0
2.0
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
18
149
1.40
0.38
4.9
5.1
—
0.0
—
0
26
(42870588) Differential panel, method unspecified - Blood
12
92
1.44
0.38
7.8
4.7
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
18
150
1.38
0.36
3.1
3.8
—
0.0
—
0
26
(3035350) Ketones [Presence] in Urine by Test strip
18
151
1.36
0.34
3.0
3.7
—
0.0
—
0
27
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
9
115
0.72
0.34
3.2
3.9
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
13
104
1.38
0.32
2.8
2.4
u/l
58.3
54.4
0.29
13
95
(3019150) Specific gravity of Urine by Refractometry
8
64
1.32
0.30
3.1
4.0
—
1.0
—
0
9
(3013826) Glucose [Moles/volume] in Serum or Plasma
22
193
1.33
0.30
2.3
3.6
mmol/l
6.6
6.7
0.08
22
177
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
5
42
1.22
0.22
2.0
2.2
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
10
121
0.76
0.22
1.4
3.3
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.22
0.0
1.5
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
0
10
0.00
0.22
0.0
1.4
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
12
0.00
0.21
0.0
1.9
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
2.8
—
—
—
0
0
(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
0
13
0.00
0.21
0.0
2.1
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
17
150
1.24
0.19
4.5
4.6
mmol/l
1.2
1.2
0.25
17
136
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
13
117
1.17
0.10
3.0
1.7
pmol/l
83.8
96.7
—
8
60
(3029937) Albumin [Presence] in Urine by Test strip
7
82
0.82
0.08
3.0
4.2
—
0.0
—
0
26
(3013512) EKG study
10
107
0.91
0.02
5.4
3.5
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
14
135
1.06
0.00
2.2
2.1
—
—
—
0
0
(3040151) Glucose [Moles/volume] in Capillary blood
0
6
0.00
0.00
0.0
26.3
—
6.0
—
0
6
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
7.2
—
181.3
—
0
6
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
5
54
0.91
0.00
1.2
1.5
—
—
—
0
0
(3003434) Protein [Mass/volume] in Pleural fluid
0
6
0.00
0.00
0.0
1.2
—
24.1
—
0
6
(4306422)
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3001788) Aldosterone [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
328.3
—
0
6
(3021387) Prolactin [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
191.8
—
0
6
(40760888) Immunoglobulin light chains.free panel - Serum
0
6
0.00
0.00
0.0
9.7
—
—
—
0
0
(3036782) Glucose [Moles/volume] in Pleural fluid
0
6
0.00
0.00
0.0
1.0
—
6.9
—
0
6
(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation
0
6
0.00
0.00
0.0
1.0
—
181.5
—
0
6
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
3.3
—
1.4
—
0
7
(4268621)
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0
(21494434) Karyotype in Bone marrow
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011985) Renin [Units/volume] in Plasma
0
7
0.00
0.00
0.0
1.1
—
14.3
—
0
7
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3024980) IgG subclass 4 [Mass/volume] in Serum
0
5
0.00
0.00
0.0
1.8
—
0.5
—
0
5
(3003740) Influenza virus B Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
4.5
—
18.0
—
0
8
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
5
0.00
0.00
0.0
5.6
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
40.8
—
0
8
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
2.3
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(4281824)
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3015235) Bicarbonate [Moles/volume] in Capillary blood
0
9
0.00
0.00
0.0
1.4
—
26.7
—
0
9
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
5
0.00
0.00
0.0
1.0
—
211.7
—
0
5
(3045424) Erythrocytes [Presence] in Urine
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
7
78
0.87
0.00
1.3
1.2
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026179) Normetanephrine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
0.4
—
0
5
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_FLEXION and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have M13_FLEXION.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: M13_FLEXION – Flexion deformity
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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