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This is a non-core endpoint: only basic statistics are computed.

Soft tissue disorders in diseases classified elsewhere

M13_SOFTTISSUEINOTH

musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M73*
  • Cause of death: ICD-10 M73*

2 out of 7 registries used, show all original rules.

27

4. Check minimum number of events

None

27

5. Include endpoints

None

27

6. Filter based on genotype QC (FinnGen only)

27

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 239 122 116
Only index persons 226 117 109
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 49.88 49.37 50.50
Only index persons 49.69 49.02 50.42

-FinnGen-

Key figures

All Female Male
Number of individuals 27 17 10
Unadjusted period prevalence (%) 0.01 0.01 0.00
Median age at first event (years) 52.54 52.57 52.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
19
65
7.43
5.66
8.4
3.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
13
43
4.90
3.88
9.8
2.7
—
—
—
0
0
(3015736) pH of Urine
17
72
4.67
3.67
8.4
2.6
—
—
—
0
0
(3019060) Gas panel - Arterial blood
6
9
8.17
3.04
3.3
6.3
—
—
—
0
0
(3002173) Hemoglobin [Mass/volume] in Arterial blood
7
16
5.50
2.68
4.3
12.5
g/l
119.4
116.4
—
7
16
(3041096) Erythrocytes [Presence] in Urine by Automated
12
48
3.70
2.62
3.2
3.1
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
7
18
4.86
2.44
1.4
1.9
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
9
30
3.97
2.43
3.2
1.4
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
8
25
4.10
2.32
1.3
1.6
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
13
63
3.05
2.01
5.8
2.8
u/l
26.8
30.9
0.60
13
57
(4010399)
6
17
4.22
1.96
2.5
1.7
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
5
12
4.84
1.91
5.4
9.3
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
7
24
3.56
1.87
1.3
1.5
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
7
24
3.56
1.87
12.6
5.5
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
9
37
3.13
1.68
5.1
4.5
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
7
28
3.01
1.58
1.7
1.3
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
5
17
3.36
1.42
3.0
1.6
—
—
—
0
0
(3044889) 12 lead EKG panel
21
150
2.79
1.40
4.8
3.9
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
20
140
2.65
1.38
8.3
3.6
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
8
38
2.56
1.32
1.3
1.6
—
—
—
0
0
(4035726)
0
33
0.00
1.26
0.0
1.5
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
7
34
2.42
1.13
1.3
1.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
5
22
2.55
1.08
1.2
1.6
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
11
65
2.17
1.01
4.5
2.5
—
—
—
0
0
(3004789) Transferrin [Mass/volume] in Serum or Plasma
6
29
2.37
0.96
1.8
2.3
g/l
2.4
2.3
—
6
29
(42870588) Differential panel, method unspecified - Blood
11
69
2.00
0.85
7.1
3.8
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
10
61
2.02
0.83
3.6
3.6
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
19
146
2.01
0.81
7.1
3.6
mm/h
14.1
13.5
0.08
19
127
(3007853) Bacteria identified in Skin by Aerobe culture
5
25
2.22
0.77
4.6
1.7
—
—
—
0
0
(3014576) Chloride [Moles/volume] in Serum or Plasma
5
25
2.22
0.77
2.4
9.2
mmol/l
101.6
104.0
—
5
25
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
21
176
1.87
0.68
10.6
7.3
u/l
78.4
80.1
0.09
21
165
(3019225) pH of Specimen
0
20
0.00
0.63
0.0
4.0
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
0
21
0.00
0.63
0.0
1.5
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
16
126
1.66
0.53
3.1
2.7
—
—
—
0
0
(3002256) Pathology report gross observation
5
32
1.69
0.45
1.0
1.4
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
22
194
1.72
0.43
26.5
15.9
%
14.1
13.8
0.39
22
187
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
5
35
1.52
0.42
7.2
3.2
ng/l
13.2
53.2
—
5
30
(3023520) Reticulocytes [#/volume] in Blood
0
18
0.00
0.41
0.0
1.4
—
80.3
—
0
10
(3026493) Urate [Moles/volume] in Serum or Plasma
6
40
1.64
0.40
3.7
2.8
umol/l
313.8
7530.1
—
6
31
(3018418) pH of Serum or Plasma
10
74
1.56
0.39
1.9
4.4
—
7.4
—
0
15
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
7
53
1.43
0.34
6.3
4.9
ug/l
2.2
1.7
—
7
43
(1761868) Lipid panel - Serum or Plasma
6
82
0.66
0.29
2.0
3.3
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
9
75
1.30
0.29
2.7
3.8
mmol/l
2.3
2.4
—
9
68
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
5
37
1.43
0.25
1.2
1.3
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
13
109
1.37
0.25
6.5
3.4
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
6
47
1.35
0.22
2.0
1.5
nmol/l
21.0
20.1
—
6
35
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.22
0.0
1.1
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
0
11
0.00
0.22
0.0
3.0
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
11
0.00
0.22
0.0
1.3
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
11
0.00
0.22
0.0
1.7
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
(3013512) EKG study
5
66
0.70
0.20
1.8
4.3
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
16
142
1.31
0.19
3.8
2.3
u/l
102.4
47.4
0.68
16
133
(3044640) Blood type and Crossmatch panel - Blood
7
83
0.79
0.18
2.6
1.9
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
8
72
1.16
0.09
4.1
3.0
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
10
96
1.07
0.00
1.7
2.2
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
13
128
1.03
0.00
5.8
4.9
mmol/l
7.0
6.5
0.29
13
119
(3003694) ABO and Rh group [Type] in Blood
5
53
0.93
0.00
1.0
1.5
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
6
61
0.98
0.00
3.8
3.1
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
0
5
0.00
0.00
0.0
1.0
—
4.5
—
0
5
(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting
0
5
0.00
0.00
0.0
1.2
—
0.8
—
0
5
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
6
0.00
0.00
0.0
3.2
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
6
60
1.00
0.00
2.8
2.0
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
21
211
0.98
0.00
17.5
13.9
ml/min/173m2
82.2
79.5
0.27
14
179
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
0
6
0.00
0.00
0.0
2.2
—
4.0
—
0
6
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
0.00
0.0
1.3
—
169.0
—
0
6
(3027315) Oxygen [Partial pressure] in Blood
0
5
0.00
0.00
0.0
1.0
—
10.3
—
0
5
(4034850)
0
8
0.00
0.00
0.0
5.9
—
—
—
0
0
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
431.5
—
0
6
(3021901) Oxygen saturation in Capillary blood
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_SOFTTISSUEINOTH and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_SOFTTISSUEINOTH.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: M13_SOFTTISSUEINOTH – Soft tissue disorders in diseases classified elsewhere

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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