Unspecified pneumoconiosis

J10_NASPNEUMOC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — J64 Hospital discharge: ICD-9 — 505 Hospital discharge: ICD-8 — 51599 Cause of death: ICD-10 — J64 Cause of death: ICD-9 — 505 Cause of death: ICD-8 — 51599 2 out of 7 registries used, show all original rules.	43
4. Check minimum number of events None	43
5. Include endpoints None	43
6. Filter based on genotype QC (FinnGen only)	43

Control definitions (FinnGen only)

Control exclude: J10_EXTERLUNG

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: J60-J70
Name in latin: Pneumoconiosis non specificata

NAME	J10_NASPNEUMOC
CONTROL_EXCLUDE	J10_EXTERLUNG
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	J64
HD_ICD_9	505
HD_ICD_8	51599
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	J64
COD_ICD_9	505
COD_ICD_8	51599
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Unspecified pneumoconiosis based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	463	139	313
Only index persons	245	81	164
Unadjusted period prevalence (%)
Whole population	0.01	0.00	0.01
Only index persons	0.01	0.00	0.01
Median age at first event (years)
Whole population	61.85	64.65	60.61
Only index persons	53.11	53.48	52.93

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	43	8	35
Unadjusted period prevalence (%)	0.01	0.00	0.02
Median age at first event (years)	53.14	48.37	54.23

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3044889) 12 lead EKG panel

215

0.39

2.04

5.3

4.3

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.94

0.88

3.7

4.6

—

(3024354) Oxygen [Partial pressure] in Venous blood

0.00

0.82

0.0

2.8

—

4.1

—

(40761511) CBC panel - Blood by Automated count

308

0.61

0.76

17.8

14.7

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

2.13

0.75

1.6

1.8

—

(40761536) Microorganisms panel - Urine sediment

2.13

0.75

2.4

4.2

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

123

0.57

0.68

8.1

3.7

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

303

0.64

0.63

19.3

15.0

16.4

26.3

mg/l

1.13

251

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.00

0.62

0.0

1.8

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.00

0.62

0.0

1.3

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.00

0.62

0.0

1.5

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.00

0.62

0.0

1.8

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.59

0.61

1.5

1.7

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.00

0.61

0.0

2.1

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

0.00

0.60

0.0

6.6

—

24.5

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.58

0.54

1.0

1.7

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

160

0.65

0.53

3.3

2.6

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

190

0.68

0.51

3.6

5.5

6.4

7.1

mmol/l

1.05

182

(40758558) Short blood count panel - Blood

1.53

0.44

4.5

7.4

—

(3018010) Neutrophils/100 leukocytes in Blood

136

1.41

0.43

4.9

5.9

55.3

58.3

0.62

126

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.42

0.0

3.8

—

38.8

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

0.00

0.42

0.0

5.5

—

118.4

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

0.00

0.42

0.0

1.2

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

0.00

0.42

0.0

14.4

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.50

0.37

2.0

2.6

2.1

1.8

—

(3023368) Bacteria identified in Blood by Culture

102

1.39

0.35

3.2

3.9

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

308

0.74

0.33

20.4

18.7

83.5

89.5

umol/l

0.40

308

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.29

0.28

3.1

3.4

—

(3026008) Bacteria identified in Urine by Culture

0.68

0.27

2.0

2.7

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

122

0.77

0.23

3.1

2.6

85.6

150.8

ug/l

—

110

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.21

0.22

1.0

1.7

—

(3042936) Bacteria identified in Isolate by Culture

1.21

0.22

1.2

1.4

—

(3008898) HLA-B27 [Presence]

0.00

0.21

0.0

1.2

—

(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood

0.00

0.21

0.0

5.6

—

1.1

—

(3007930) Methemoglobin/Hemoglobin.total in Blood

0.00

0.21

0.0

6.0

—

0.8

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(4094501)

0.00

0.21

0.0

1.1

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.7

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

0.00

0.21

0.0

2.5

—

0.7

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

53.1

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.21

0.0

1.2

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

0.00

0.20

0.0

1.4

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.20

0.0

3.6

—

40.4

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

0.20

0.0

7.4

—

25.1

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

0.00

0.20

0.0

2.6

—

1.2

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

1.28

0.20

2.0

3.4

29.9

30.4

u/l

0.04

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.22

0.19

1.9

2.0

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

140

0.80

0.19

2.9

4.4

20.9

21.6

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.18

0.19

2.6

2.3

g/l

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

129

0.80

0.18

5.5

5.2

33.1

35.0

g/l

0.39

123

(3015736) pH of Urine

112

1.23

0.17

2.8

3.5

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

0.79

0.15

2.4

3.6

2.3

mmol/l

—

(3031040) Bacteria [#/volume] in Urine by Automated count

198

0.84

0.15

4.6

4.0

—

183.3

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.09

0.08

2.7

2.6

10.1

14.2

umol/l

—

(42870588) Differential panel, method unspecified - Blood

1.15

0.07

4.9

5.8

—

(3013707) Erythrocyte sedimentation rate by Westergren method

212

0.89

0.07

5.4

4.2

16.3

14.1

mm/h

0.15

196

(1761868) Lipid panel - Serum or Plasma

0.89

0.07

2.1

3.1

—

(36304419) Bacteria [Presence] in Urine

1.13

0.05

3.2

2.9

—

(3009542) Hematocrit [Volume Fraction] of Blood

258

0.93

0.03

14.4

17.4

40.7

39.7

0.30

190

(3037467) Urinalysis macro (dipstick) panel - Urine

198

0.93

0.03

5.6

4.5

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

114

1.07

0.01

2.9

4.0

—

(40768804) Tissue Pathology biopsy report

107

1.04

0.00

2.5

1.9

—

(3032080) INR in Blood by Coagulation assay

144

0.96

0.00

7.7

8.2

1.3

inr

—

(3018095) Leukocytes [#/volume] in Urine

118

1.02

0.00

3.8

3.7

5.5

120.5

e6/l

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.0

1.3

—

(3016879) Cocaine [Presence] in Urine

0.00

0.0

1.0

—

(44790047)

0.00

0.0

1.4

—

(3024928) Oxygen saturation in Venous blood

0.00

0.0

1.9

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

2.0

—

166.8

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

0.92

0.00

3.3

2.3

60.3

52.1

u/l

—

(3021960) Folate [Moles/volume] in Serum or Plasma

0.96

0.00

2.3

1.7

14.2

21.5

nmol/l

—

(44790049)

0.00

0.0

1.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.02

0.00

2.8

3.8

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

0.91

0.00

1.3

1.7

418.3

422.3

pmol/l

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

1.2

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

120

1.00

0.00

3.0

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

1.0

—

(40768800) Prostate Pathology biopsy report

0.00

0.0

1.1

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

0.00

0.0

2.0

—

93.3

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.0

1.1

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.2

—

86.0

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.0

1.0

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.2

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.0

1.0

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.0

1.2

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.2

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(40768797) Stomach Pathology biopsy report

0.90

0.00

1.0

1.3

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.0

1.0

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

0.89

0.00

3.3

1.9

2.3

3.3

mg/l

—

(3044640) Blood type and Crossmatch panel - Blood

0.96

0.00

2.6

2.2

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

3.2

—

5.0

—

(3027008) Opiates [Presence] in Urine

0.00

0.0

1.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

3.2

—

4.0

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.0

5.4

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

1.7

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

3.2

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

30.5

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(44806118)

0.00

0.0

1.4

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

1.2

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

0.0

1.3

—

15.2

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(40768443) Skin Pathology biopsy report

0.00

0.0

1.3

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.2

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.2

—

(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting

0.00

0.0

1.2

—

0.7

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.0

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

3.6

—

203.9

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.0

1.0

—

(3047181) Lactate [Moles/volume] in Blood

0.00

0.0

11.7

—

1.5

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

2.9

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.0

3.9

—

1.6

—

(3036489) Thrombin time

0.00

0.0

2.2

—

19.2

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.0

2.0

—

1.4

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.5

—

91.6

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.3

—

13.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.0

1.2

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.6

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.0

1.2

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.0

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.0

1.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

3.2

—

107.4

—

(3013512) EKG study

0.97

0.00

2.5

4.7

—

(44790048)

0.00

0.0

1.4

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.0

3.9

—

7.2

—

(3017569) Oxygen content in Arterial blood

0.00

0.0

2.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint J10_NASPNEUMOC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have J10_NASPNEUMOC.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: J10_NASPNEUMOC – Unspecified pneumoconiosis

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Unspecified pneumoconiosis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints