Polydactyly

Q17_POLYDACTYLY

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Q69 Cause of death: ICD-10 — Q69 2 out of 7 registries used, show all original rules.	45
4. Check minimum number of events None	45
5. Include endpoints None	45
6. Filter based on genotype QC (FinnGen only)	45

Control definitions (FinnGen only)

Control exclude: Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: Q6[5-9]|Q7
Name in latin: Polydactylia

NAME	Q17_POLYDACTYLY
CONTROL_EXCLUDE	Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q69
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q69
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Polydactyly based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	2140	940	1200
Only index persons	1229	549	680
Unadjusted period prevalence (%)
Whole population	0.03	0.03	0.03
Only index persons	0.02	0.02	0.03
Median age at first event (years)
Whole population	-	0.37	0.30
Only index persons	0.81	1.03	0.64

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	45	24	21
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	3.58	6.28	0.49

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

1.62

0.0

1.9

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

3.61

1.56

2.6

—

(3020682) Albumin/Creatinine [Ratio] in Urine

2.51

1.53

3.8

3.5

1.1

12.1

mg/mmol

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.72

1.35

1.7

1.0

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.00

1.22

0.0

1.9

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

2.68

1.18

2.4

3.0

5.2

4.7

pmol/l

—

(3020961) Endomysium IgA Ab [Titer] in Serum

2.11

1.02

1.1

1.2

—

(3008898) HLA-B27 [Presence]

0.00

1.02

0.0

1.0

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

1.02

0.0

2.1

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

1.01

0.0

1.1

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

113

0.46

1.01

1.3

1.8

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.82

0.0

2.0

—

220.8

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

0.00

0.82

0.0

1.9

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.82

0.0

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.81

0.0

1.5

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.81

0.0

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.80

0.0

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.80

0.0

1.5

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.80

0.0

1.5

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.80

0.0

1.5

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

1.76

0.78

1.6

112.1

100.8

pmol/l

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

0.00

0.62

0.0

23.2

—

122.7

—

(3003327) Ova and parasites identified in Stool by Light microscopy

0.00

0.62

0.0

1.7

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

254

0.68

0.57

3.5

3.3

4.6

4.4

mmol/l

0.77

236

(40760892) CBC W Ordered Manual Differential panel - Blood

1.58

0.56

4.8

5.3

—

(3003694) ABO and Rh group [Type] in Blood

125

0.65

0.53

1.3

1.8

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

166

0.70

0.44

1.5

2.0

—

(3009508) Creatinine [Moles/volume] in Urine

1.47

0.43

4.7

2.5

6.2

8.9

mmol/l

0.75

(40768804) Tissue Pathology biopsy report

1.47

0.43

1.9

1.8

—

(3007449) CD3+CD8+ (T8 suppressor) cells/100 cells in Blood

0.00

0.42

0.0

1.8

—

24.7

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.42

0.0

1.3

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

0.00

0.42

0.0

57.1

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

216

0.72

0.41

4.9

3.6

35.7

36.2

mmol/mol

0.09

197

(3025271) CD3-CD16+CD56+ (Natural killer) cells [#/volume] in Blood

0.00

0.41

0.0

1.7

—

0.2

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

0.00

0.41

0.0

24.5

—

0.7

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

0.00

0.41

0.0

23.3

—

1.1

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.41

0.0

1.2

—

(3001405) CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood

0.00

0.41

0.0

1.7

—

399.5

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.41

0.0

1.2

—

(40761511) CBC panel - Blood by Automated count

372

1.68

0.40

9.2

—

(3018095) Leukocytes [#/volume] in Urine

120

1.38

0.36

8.5

2.9

82.8

25.0

e6/l

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.35

0.34

8.3

14.5

24.0

23.9

mmol/l

—

(36304419) Bacteria [Presence] in Urine

1.40

0.34

9.2

2.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

129

0.71

0.34

1.7

2.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

109

0.68

0.34

7.9

3.2

—

(3015736) pH of Urine

128

0.72

0.32

4.0

3.0

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

373

0.72

0.29

3.2

3.7

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

163

1.29

0.28

3.6

3.0

50.2

74.5

ug/l

0.63

149

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.25

0.27

3.4

3.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

135

0.75

0.26

5.0

5.8

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.35

0.24

2.2

1.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.21

0.22

1.2

2.0

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3020044) Glucose [Moles/volume] in Cerebral spinal fluid

0.00

0.21

0.0

5.6

—

3.5

—

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

5.0

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.21

0.0

1.3

—

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.21

0.0

2.8

—

(3019060) Gas panel - Arterial blood

0.00

0.21

0.0

46.8

—

(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

1.0

—

1.8

—

(3024928) Oxygen saturation in Venous blood

0.00

0.21

0.0

36.5

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

35.9

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

0.00

0.21

0.0

5.3

—

293.2

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.21

0.0

1.1

—

(3020891) Body temperature

0.00

0.21

0.0

7.6

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.20

0.0

6.6

—

64.6

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.20

0.0

1.3

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

0.20

0.0

6.5

—

22.7

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.0

—

3.7

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

111

1.24

0.18

9.2

2.9

—

(3023368) Bacteria identified in Blood by Culture

1.15

0.18

2.6

4.9

—

(3009542) Hematocrit [Volume Fraction] of Blood

362

1.32

0.16

14.0

15.8

39.1

39.7

0.34

316

(3001604) Monocytes [#/volume] in Blood

201

1.18

0.16

6.0

9.1

0.5

e9/l

0.12

176

(42870588) Differential panel, method unspecified - Blood

134

1.18

0.13

8.4

11.5

—

(3037467) Urinalysis macro (dipstick) panel - Urine

216

0.87

0.12

6.8

3.8

—

(3021960) Folate [Moles/volume] in Serum or Plasma

1.12

0.10

1.8

1.3

24.1

19.3

nmol/l

—

(3012544) pH of Venous blood

1.06

0.09

8.5

14.1

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.85

0.08

1.5

2.0

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.05

0.08

7.3

2.3

—

(3026008) Bacteria identified in Urine by Culture

1.09

0.07

7.3

2.6

—

(3044640) Blood type and Crossmatch panel - Blood

100

1.13

0.06

3.5

3.1

—

(40758558) Short blood count panel - Blood

110

0.88

0.05

11.7

8.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

359

0.89

0.04

12.1

41.5

20.7

mg/l

1.20

253

(3044889) 12 lead EKG panel

168

0.93

0.03

2.9

2.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

106

0.93

0.01

2.3

2.6

—

(3000991) Gas panel - Venous blood

1.04

0.00

10.3

15.0

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.0

1.5

—

(4198724)

0.00

0.0

2.3

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

9.4

—

805.0

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.0

—

96.1

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.2

—

(3041672) Baker's yeast Ab [Presence] in Serum

0.00

0.0

1.4

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

4.2

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

10.0

—

1597.0

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.03

0.00

2.0

3.2

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

1.9

—

(3006598) pH of Arterial cord blood

0.00

0.0

1.0

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.1

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3005082) Progesterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

42.8

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.8

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.0

1.6

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

8.0

—

0.6

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.4

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.0

3.4

—

1.5

—

(4062490)

0.00

0.0

1.3

—

(3003932) Carbon dioxide [Partial pressure] in Arterial cord blood

0.00

0.0

1.0

—

7.8

—

(3011985) Renin [Units/volume] in Plasma

0.00

0.0

1.0

—

23.7

—

(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

28.8

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

7.5

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

2.6

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3022493) Free Hemoglobin [Mass/volume] in Plasma

0.00

0.0

3.0

—

214.2

—

(3015076) Soybean IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(1761868) Lipid panel - Serum or Plasma

0.94

0.00

1.5

1.8

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.92

0.00

1.8

—

(3003985) Beta hydroxybutyrate [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

2.5

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.00

0.0

6.0

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

100

1.00

0.00

2.3

2.4

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

64.0

—

(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood

0.00

0.0

1.0

—

18.8

—

(3005011) Chlamydia sp Ab [Titer] in Serum

0.00

0.0

1.2

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(44790047)

0.00

0.0

1.6

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3026725) Estradiol (E2) [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

0.2

—

(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood

0.00

0.0

62.3

—

1.6

—

(44806118)

0.00

0.0

1.6

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.1

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.2

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.1

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.8

—

(3024471) HLA-A [Type]

0.00

0.0

1.0

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3007930) Methemoglobin/Hemoglobin.total in Blood

0.00

0.0

71.3

—

1.0

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.0

2.3

—

(3020393) Adenovirus Ag [Presence] in Stool

0.00

0.0

1.7

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

3.8

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3024932) HLA-DR beta [Type]

0.00

0.0

1.2

—

(3004959) Base excess in Arterial cord blood by calculation

0.00

0.0

1.0

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

2.1

—

(4268621)

0.00

0.0

1.9

—

(44790048)

0.00

0.0

1.6

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

1.5

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.2

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

0.0

1.1

—

152.3

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.4

—

(3011648) Oxygen content in Venous blood

0.00

0.0

48.3

—

12.3

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.0

2.3

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.0

3.0

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.1

—

(44790049)

0.00

0.0

1.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_POLYDACTYLY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_POLYDACTYLY.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: Q17_POLYDACTYLY – Polydactyly

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Polydactyly

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints