Medullary carcinoma of thyroid gland, excluding all cancers (controls excluding all cancers)

C3_THYROID_MEDULLARY_EXALLC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — C73.94& Hospital discharge: ICD-9 — 193D Cause of death: ICD-10 — C73.94& Cause of death: ICD-9 — 193D Cancer registry: Topography ICD-O-3 — C73 Cancer registry: Morphology ICD-O-3 — 8510\|8513 Cancer registry: Behaviour codes — 3 3 out of 7 registries used, show all original rules.	73
4. Check minimum number of events None	73
5. Include endpoints None	73
6. Filter based on genotype QC (FinnGen only)	73

Control definitions (FinnGen only)

Control exclude: C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze: DF12

NAME	C3_THYROID_MEDULLARY_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE_EXALLC
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	C7394
HD_ICD_9	193D
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	C7394
COD_ICD_9	193D
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO	C73
CANC_TOPO_EXCL
CANC_MORPH	8510\|8513
CANC_MORPH_EXCL
CANC_BEHAV	3

Similar endpoints

↥

List of similar endpoints to Medullary carcinoma of thyroid gland, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Medullary carcinoma of thyroid gland

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	73	53	20
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	47.61	45.64	52.83

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3018840) Calcitonin [Moles/volume] in Serum or Plasma

+∞

77.45

9.8

0.0

711.8

—

pmol/l

—

(4035726)

27.77

36.09

1.5

1.1

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

80.75

34.17

2.9

1.1

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

86.16

33.63

2.6

1.3

—

nmol/l

—

(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma

83.87

25.15

5.0

1.2

16.8

—

u/ml

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

51.33

18.91

1.8

1.0

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

245

12.47

17.52

11.3

4.3

1.2

mmol/l

1.29

222

(3018418) pH of Serum or Plasma

159

6.90

15.08

9.9

2.6

7.4

—

(3044640) Blood type and Crossmatch panel - Blood

153

3.47

6.35

3.1

1.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

251

3.45

6.09

4.6

3.6

—

(40768804) Tissue Pathology biopsy report

195

3.33

6.00

2.6

1.6

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

3.87

5.78

5.4

1.8

0.8

mmol/l

0.15

(3002256) Pathology report gross observation

4.27

5.40

1.4

1.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

122

2.76

3.86

2.8

1.7

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

286

2.36

3.12

10.6

3.4

10.2

10.8

umol/l

0.38

266

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

5.14

3.01

1.9

1.8

166.9

2.9

ug/l

—

(3032080) INR in Blood by Coagulation assay

210

2.28

2.95

14.8

6.8

1.4

1.2

inr

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

338

2.23

2.64

8.4

5.5

3.5

4.2

e9/l

1.86

294

(3019060) Gas panel - Arterial blood

3.80

2.58

6.0

3.7

—

(40758558) Short blood count panel - Blood

129

2.28

2.57

5.8

5.0

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

2.75

2.55

2.8

4.2

1.1

1.0

mmol/l

0.17

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

3.77

2.35

3.0

7.2

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

2.83

2.21

4.9

6.1

125.4

127.7

g/l

0.14

(3036481) Cortisol [Moles/volume] in Serum or Plasma

2.61

2.20

1.9

1.6

521.1

410.4

nmol/l

0.25

(3003694) ABO and Rh group [Type] in Blood

145

2.10

2.18

1.5

1.4

—

(3039000) Anion gap in Blood

5.27

2.10

3.8

3.6

9.0

9.9

mmol/l

—

(3018572) Chloride [Moles/volume] in Blood

5.27

2.10

3.8

3.6

108.4

106.0

mmol/l

—

(3052851) Hemolysis interference index of Serum or Plasma

3.99

1.98

1.7

2.5

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.11

1.77

1.9

5.8

26.8

25.0

mmol/l

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

589

2.67

1.77

18.4

9.5

87.9

81.4

ml/min/173m2

1.62

462

(3044889) 12 lead EKG panel

405

1.86

1.60

4.9

3.4

—

(3019225) pH of Specimen

2.24

1.54

16.2

4.1

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.88

1.46

1.3

1.7

0.9

0.6

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.75

1.40

1.3

1.7

0.9

0.8

—

(3022313) Gas panel - Capillary blood

3.08

1.38

8.8

3.1

—

(3000991) Gas panel - Venous blood

2.52

1.34

1.8

7.2

—

(3037467) Urinalysis macro (dipstick) panel - Urine

432

0.60

1.30

3.7

4.0

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.24

1.23

4.8

3.1

—

(42870588) Differential panel, method unspecified - Blood

184

1.64

1.13

4.3

5.5

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.17

1.06

2.4

1.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.99

1.02

2.1

1.6

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

1.00

0.0

1.4

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

1.00

0.0

1.6

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.95

0.97

2.1

1.5

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.83

0.96

1.7

1.9

28.7

30.0

u/l

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.33

0.96

6.0

7.9

0.5

0.7

—

(3002032) Base excess in Venous blood by calculation

1.92

0.89

1.4

2.6

3.1

1.8

mmol/l

—

(3012544) pH of Venous blood

1.83

0.86

1.4

2.6

—

(3020682) Albumin/Creatinine [Ratio] in Urine

192

0.61

0.83

3.7

3.9

1.6

7.0

mg/mmol

—

115

(3023368) Bacteria identified in Blood by Culture

117

1.59

0.81

4.4

3.9

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.72

0.81

2.2

1.5

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.81

0.0

1.2

—

(3002385) Erythrocyte distribution width [Ratio]

507

1.57

0.79

21.7

12.8

13.5

0.21

500

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.78

0.72

2.7

2.1

0.2

g/l

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.91

0.70

6.8

8.1

1.3

1.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

173

0.63

0.68

2.9

3.4

—

(3015736) pH of Urine

246

0.69

0.64

2.8

3.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

235

0.69

0.63

2.8

3.6

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.60

0.60

3.5

2.1

5.3

5.0

umol/l

0.11

(3042936) Bacteria identified in Isolate by Culture

1.57

0.57

1.5

2.0

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

143

0.65

0.54

2.9

3.1

—

(40760892) CBC W Ordered Manual Differential panel - Blood

138

1.40

0.52

1.9

3.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.47

0.42

1.7

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.41

0.0

1.3

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.41

0.0

1.3

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

0.41

0.0

1.1

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.41

0.0

1.1

—

(3006184) Hemoglobin [Mass/volume] in Capillary blood

0.00

0.41

0.0

1.5

—

128.1

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.41

0.0

1.6

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.41

0.0

1.3

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.41

0.0

4.8

—

19.9

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.41

0.0

1.1

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.40

0.0

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.40

0.0

1.4

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.40

0.0

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.40

0.0

1.4

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.40

0.0

1.4

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.39

0.0

1.2

—

0.2

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.39

0.0

1.6

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.39

0.0

1.2

—

1.2

—

(40761535) Cells panel - Urine sediment

1.47

0.36

3.3

3.2

—

(40768797) Stomach Pathology biopsy report

1.36

0.34

1.1

1.2

—

(3022621) pH of Urine by Test strip

1.33

0.34

2.2

2.5

—

(3026008) Bacteria identified in Urine by Culture

173

0.76

0.33

2.3

3.0

—

(3022145) Colonoscopy Study observation

1.26

0.28

1.0

1.4

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.38

0.24

1.2

1.4

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.30

0.23

2.4

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

626

1.35

0.23

17.5

10.7

28.6

20.6

mg/l

1.01

464

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

113

0.77

0.22

1.3

1.4

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.21

0.0

1.1

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.21

0.0

1.2

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

8.6

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.21

0.0

2.1

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.21

0.0

3.0

—

14.0

—

(4306422)

0.00

0.21

0.0

1.1

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3000475) Leukocytes [#/volume] in Synovial fluid

0.00

0.21

0.0

1.2

—

4960.8

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.0

—

(3041067) Sjogrens syndrome-A extractable nuclear 52kD Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

94.4

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.3

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.6

—

(3049717) Cytology report of Urine Cyto stain

0.00

0.20

0.0

1.6

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

119

1.22

0.19

1.1

1.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

193

0.84

0.18

2.3

2.9

—

(1761868) Lipid panel - Serum or Plasma

244

0.86

0.18

2.7

3.0

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.14

0.17

1.8

—

(3009542) Hematocrit [Volume Fraction] of Blood

568

0.87

0.13

20.5

11.4

41.4

40.3

0.51

418

(3007164) IgA [Mass/volume] in Serum or Plasma

124

1.16

0.12

1.6

1.3

1.7

2.5

g/l

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.14

0.09

3.7

2.8

1.7

1.4

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.12

0.09

1.5

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

235

0.91

0.09

1.8

83.0

104.9

pmol/l

1.26

110

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.81

0.08

1.6

1.7

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.82

0.08

2.2

2.4

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.12

0.08

1.1

1.8

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.82

0.08

11.5

5.9

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.14

0.07

1.5

1.6

—

(36304419) Bacteria [Presence] in Urine

152

0.90

0.07

2.5

2.7

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

103

0.86

0.07

1.9

2.0

—

(3013512) EKG study

179

1.08

0.05

5.1

3.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

389

1.06

0.04

2.5

3.0

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

230

1.06

0.04

3.8

3.1

19.5

51.3

ng/l

1.12

154

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

1.09

0.02

4.3

3.2

27.3

24.3

—

(3018095) Leukocytes [#/volume] in Urine

206

0.96

0.00

2.8

3.8

102.9

70.3

e6/l

0.13

139

(3021589) Normoblasts [#/volume] in Blood

247

1.02

0.00

9.4

7.6

0.0

e9/l

0.00

198

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.1

—

(4027681)

0.00

0.0

1.1

—

(4024509)

0.00

0.0

1.6

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.0

1.6

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.2

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.0

1.3

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.92

0.00

1.4

1.5

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.3

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

7.6

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.1

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

1.4

—

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

2.5

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.0

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

0.0

2.5

—

62.0

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.2

—

5.8

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

0.0

1.3

—

1.7

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

1.0

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

0.0

1.3

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

1.3

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.3

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.0

1.3

—

(3021788) Differential panel - Synovial fluid

0.00

0.0

1.5

—

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

1.0

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.8

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

1.7

—

(3006270) Folate [Moles/volume] in Blood

0.00

0.0

1.0

—

405.6

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

3.2

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.0

2.8

—

(4268621)

0.00

0.0

1.6

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

1.4

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

0.87

0.00

2.2

1.5

1.3

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.2

—

(3015183) Erythrocyte sedimentation rate

0.00

0.0

1.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.1

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.0

1.3

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.1

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.0

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.2

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.2

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.90

0.00

2.0

2.6

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.4

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.3

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.0

1.0

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.5

—

61.7

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.0

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

0.0

3.8

—

20.6

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.0

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

12.6

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.2

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_THYROID_MEDULLARY_EXALLC – Medullary carcinoma of thyroid gland, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Medullary carcinoma of thyroid gland, excluding all cancers (controls excluding all cancers)

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Medullary carcinoma of thyroid gland, excluding all cancers (controls excluding all cancers) (C3_THYROID_MEDULLARY_EXALLC)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Relationships between endpoints