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This is a non-core endpoint: only basic statistics are computed.

Malignant neoplasm of trachea, excluding all cancers (controls excluding all cancers)

C3_TRACHEA_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C33
  • Hospital discharge: ICD-9 1620
  • Hospital discharge: ICD-8 1620
  • Cause of death: ICD-10 C33
  • Cause of death: ICD-9 1620
  • Cause of death: ICD-8 1620
  • Cancer registry: Topography ICD-O-3 C33
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

35

4. Check minimum number of events

None

35

5. Include endpoints

None

35

6. Filter based on genotype QC (FinnGen only)

35

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Malignant neoplasm of trachea, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 35 9 26
Unadjusted period prevalence (%) 0.01 0.00 0.01
Median age at first event (years) 63.83 49.39 68.83

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(4035726)
6
5
14.05
3.91
3.2
1.0
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
5
7
8.08
2.63
1.6
1.7
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
10
179
0.38
1.75
7.2
4.2
mm/h
7.7
12.9
—
10
158
(3002256) Pathology report gross observation
6
19
3.59
1.74
1.8
1.1
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
16
228
0.45
1.44
34.1
15.2
umol/l
73.1
88.6
1.82
16
228
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
8
143
0.43
1.34
4.4
3.4
u/l
75.8
49.4
—
8
131
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
5
20
2.74
1.19
2.0
1.6
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
6
114
0.43
1.08
2.2
4.3
ug/l
4.3
2.5
—
6
96
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
5
22
2.48
1.07
2.0
4.0
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
0
28
0.00
1.03
0.0
4.9
—
33.5
—
0
17
(3007853) Bacteria identified in Skin by Aerobe culture
6
29
2.28
0.94
3.3
1.7
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
18
229
0.56
0.84
25.5
12.8
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
7
43
1.78
0.72
3.7
3.8
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
10
64
1.79
0.67
6.8
4.3
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
5
29
1.84
0.66
2.6
1.5
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
0
19
0.00
0.62
0.0
2.6
—
132.0
—
0
19
(3037467) Urinalysis macro (dipstick) panel - Urine
11
151
0.60
0.61
3.5
4.0
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
9
64
1.54
0.57
7.4
1.5
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
12
85
1.63
0.56
5.7
3.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
7
45
1.69
0.53
5.6
1.7
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
8
57
1.52
0.46
5.4
3.5
u/l
31.4
29.5
—
8
52
(3044640) Blood type and Crossmatch panel - Blood
8
58
1.49
0.46
6.5
2.0
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
15
0.00
0.42
0.0
2.3
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
0
15
0.00
0.42
0.0
2.3
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
15
0.00
0.42
0.0
1.2
—
—
—
0
0
(3000991) Gas panel - Venous blood
0
15
0.00
0.42
0.0
12.2
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
0
16
0.00
0.42
0.0
1.2
—
131.9
—
0
6
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
0
16
0.00
0.42
0.0
2.1
—
0.6
—
0
16
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
0
16
0.00
0.42
0.0
3.4
—
45.5
—
0
16
(3013139) Helicobacter pylori Ag [Presence] in Stool
0
17
0.00
0.42
0.0
1.1
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
0
17
0.00
0.42
0.0
2.0
—
1.6
—
0
17
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
0
17
0.00
0.42
0.0
2.1
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
5
35
1.50
0.41
5.8
1.5
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
0
18
0.00
0.41
0.0
1.3
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
0
18
0.00
0.41
0.0
2.7
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
11
84
1.45
0.35
2.1
3.0
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
8
65
1.30
0.30
1.1
3.0
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
5
73
0.63
0.29
9.0
5.1
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
8
102
0.72
0.25
8.1
4.9
%
3.0
2.9
—
8
90
(3022096) Basophils/100 leukocytes in Blood
8
101
0.73
0.25
8.1
4.8
%
0.8
0.6
—
8
89
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
11
0.00
0.22
0.0
1.4
—
—
—
0
0
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
0
11
0.00
0.22
0.0
1.1
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
0
11
0.00
0.22
0.0
1.4
—
24.7
—
0
11
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
11
0.00
0.22
0.0
1.1
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
11
0.00
0.22
0.0
1.0
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
11
0.00
0.22
0.0
1.5
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
0
10
0.00
0.22
0.0
2.2
—
1.5
—
0
10
(3038515) Glucose [Moles/volume] in Venous blood
0
10
0.00
0.22
0.0
2.2
—
7.5
—
0
10
(1002224) Polysomnography panel
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
8.4
—
25.7
—
0
12
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
14
0.00
0.20
0.0
2.4
—
—
—
0
0
(3022313) Gas panel - Capillary blood
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
0
14
0.00
0.20
0.0
1.7
—
15.7
—
0
14
(36304419) Bacteria [Presence] in Urine
8
66
1.27
0.19
1.5
2.5
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
8
69
1.21
0.18
2.0
2.2
u/l
44.9
54.3
—
8
63
(3018010) Neutrophils/100 leukocytes in Blood
9
104
0.82
0.15
6.7
4.8
%
66.5
59.3
—
9
92
(3002030) Lymphocytes/100 leukocytes in Blood
9
104
0.82
0.15
7.3
5.3
%
19.8
25.3
—
9
93
(3019069) Monocytes/100 leukocytes in Blood
9
103
0.83
0.15
7.3
5.2
%
8.7
8.6
—
9
90
(3003694) ABO and Rh group [Type] in Blood
5
43
1.19
0.10
1.8
1.3
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
10
113
0.84
0.10
3.0
2.7
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
6
57
1.06
0.09
2.8
3.3
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
10
112
0.85
0.09
6.8
4.6
e9/l
0.2
0.2
—
10
95
(3013826) Glucose [Moles/volume] in Serum or Plasma
13
142
0.87
0.08
4.5
4.2
mmol/l
7.0
6.8
0.04
13
125
(3044889) 12 lead EKG panel
15
159
0.90
0.04
4.8
4.2
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
10
107
0.91
0.02
6.7
4.7
e9/l
0.0
0.0
—
10
92
(3019198) Lymphocytes [#/volume] in Blood
10
107
0.91
0.02
6.7
5.0
e9/l
1.5
1.8
—
10
96
(3024561) Albumin [Mass/volume] in Serum or Plasma
10
97
1.04
0.00
7.3
3.8
g/l
33.6
34.7
—
10
92
(3001604) Monocytes [#/volume] in Blood
10
105
0.93
0.00
6.7
4.7
e9/l
0.6
0.6
—
10
91
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035320) C reactive protein [Mass/volume] in Body fluid
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
5.4
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010421) pH of Blood
0
5
0.00
0.00
0.0
5.4
—
7.4
—
0
5
(3013290) Carbon dioxide [Partial pressure] in Blood
0
5
0.00
0.00
0.0
5.2
—
4.8
—
0
5
(3001019) Free T4 and TSH panel - Serum or Plasma
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3023351) European house dust mite IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
0.7
—
0
5
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3023323) Follitropin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
11.4
—
0
5
(3027315) Oxygen [Partial pressure] in Blood
0
5
0.00
0.00
0.0
5.2
—
8.8
—
0
5
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
34.6
—
0
5
(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758558) Short blood count panel - Blood
5
54
0.91
0.00
15.4
3.3
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020961) Endomysium IgA Ab [Titer] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
3.4
—
692.1
—
0
8
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
0
7
0.00
0.00
0.0
1.0
—
0.0
—
0
7
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(3008898) HLA-B27 [Presence]
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
0
6
0.00
0.00
0.0
1.8
—
65.5
—
0
6
(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
0
7
0.00
0.00
0.0
6.3
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
8
0.00
0.00
0.0
1.9
—
4.2
—
0
8
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(1616796) Gas panel - Central venous blood
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
(3039162) Centromere protein B Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
8
86
0.91
0.00
15.6
8.4
e9/l
0.0
0.0
—
8
67
(3035285) Chloride [Moles/volume] in Venous blood
0
8
0.00
0.00
0.0
1.9
—
105.9
—
0
8
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
8
81
0.98
0.00
2.9
4.1
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_TRACHEA_EXALLC – Malignant neoplasm of trachea, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).