Benign neoplasm of mesothelial tissue

CD2_BENIGN_MESOTHELIAL_EXALLC

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data
1. Apply sex-specific rule None	-
2. Check conditions None
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D19 Cause of death: ICD-10 — D19 2 out of 7 registries used, show all original rules.	-
4. Check minimum number of events None	-
5. Include endpoints CD2_BENIGN_MESOTHELIAL_PLEURA CD2_BENIGN_MESOTHELIAL_PERITONEUM CD2_BENIGN_MESOTHELIAL_NOS	-
6. Filter based on genotype QC (FinnGen only) None	-

Control definitions (FinnGen only)

Control exclude: C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy: 2
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D10-D36
Name in latin: Neoplasma benignum mesotheliale

NAME	CD2_BENIGN_MESOTHELIAL_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	CD2_BENIGN_MESOTHELIAL_PLEURA\|CD2_BENIGN_MESOTHELIAL_PERITONEUM\|CD2_BENIGN_MESOTHELIAL_NOS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D19
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D19
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm of mesothelial tissue based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	42	30	12
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	48.93	44.19	60.78

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(4035726)

9.04

3.71

1.6

1.2

—

(3022145) Colonoscopy Study observation

4.21

3.28

1.3

—

(3042936) Bacteria identified in Isolate by Culture

3.28

2.51

1.5

1.8

—

(3002256) Pathology report gross observation

3.66

2.40

1.3

1.0

—

(3019060) Gas panel - Arterial blood

4.81

2.23

2.2

6.1

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

2.79

1.53

1.1

1.8

30.00

30.35

u/l

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

151

1.78

0.99

4.6

3.7

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

2.42

0.98

2.7

2.0

0.25

0.21

g/l

—

(42870588) Differential panel, method unspecified - Blood

108

1.78

0.91

3.9

4.8

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.87

0.90

1.8

—

(3025941) Bacteria identified in Stool by Culture

2.33

0.79

1.0

1.2

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.75

0.76

1.3

1.4

—

(3031040) Bacteria [#/volume] in Urine by Automated count

219

1.65

0.75

4.8

4.0

—

67.60

—

(40768804) Tissue Pathology biopsy report

123

1.64

0.74

3.0

1.7

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

105

1.67

0.73

2.5

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

180

1.61

0.73

4.3

3.7

6.93

6.44

mmol/l

0.49

167

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.80

0.73

1.6

1.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.66

0.71

3.2

2.9

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

125

1.60

0.68

3.1

3.6

—

(36304419) Bacteria [Presence] in Urine

1.65

0.63

2.5

2.3

—

(3000991) Gas panel - Venous blood

0.00

0.62

0.0

7.6

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.61

0.0

1.4

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.78

0.60

1.5

1.8

35.33

14.29

umol/l

—

(3019150) Specific gravity of Urine by Refractometry

1.68

0.59

1.7

4.6

—

1.02

—

(3044640) Blood type and Crossmatch panel - Blood

103

1.54

0.54

1.9

1.8

—

(3002385) Erythrocyte distribution width [Ratio]

294

1.57

0.54

15.5

12.2

13.17

13.49

1.12

287

(3019069) Monocytes/100 leukocytes in Blood

160

1.48

0.53

3.9

5.2

8.08

8.33

0.14

147

(3006504) Eosinophils/100 leukocytes in Blood

160

1.48

0.53

4.0

4.9

1.95

2.93

1.61

146

(3022096) Basophils/100 leukocytes in Blood

152

1.46

0.49

4.1

4.9

0.52

0.66

0.59

136

(3018010) Neutrophils/100 leukocytes in Blood

162

1.45

0.48

3.7

4.9

54.90

57.32

0.37

150

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.48

0.48

2.4

1.7

—

(3044889) 12 lead EKG panel

234

1.43

0.44

3.4

3.2

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.42

0.0

1.9

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

0.00

0.42

0.0

1.3

—

3.08

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.42

0.0

1.3

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.41

0.0

1.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

263

0.72

0.39

3.0

3.2

—

(3026008) Bacteria identified in Urine by Culture

1.43

0.37

3.3

3.0

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.42

0.36

2.3

1.5

—

(3003694) ABO and Rh group [Type] in Blood

0.68

0.36

1.1

1.4

—

(3009542) Hematocrit [Volume Fraction] of Blood

325

1.46

0.36

12.9

11.3

41.55

40.48

0.62

255

(3023368) Bacteria identified in Blood by Culture

1.44

0.34

8.7

3.5

—

(3003338) MCHC [Mass/volume]

304

1.40

0.33

14.1

13.4

333.24

331.81

g/l

0.53

304

(3002030) Lymphocytes/100 leukocytes in Blood

162

1.32

0.30

4.1

5.1

26.59

28.26

0.26

150

(40758558) Short blood count panel - Blood

1.39

0.29

3.7

3.5

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

0.65

0.29

2.0

1.9

3.16

2.68

mg/l

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

0.65

0.29

1.6

3.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.30

0.28

4.3

5.8

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

285

1.33

0.27

3.2

3.9

15.01

14.41

pmol/l

0.77

262

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.21

0.0

2.3

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

0.00

0.21

0.0

3.9

—

0.64

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.3

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.6

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.3

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.3

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.3

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.3

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

0.00

0.21

0.0

3.7

—

1.67

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.4

—

(1761868) Lipid panel - Serum or Plasma

129

1.25

0.21

2.6

2.7

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

0.00

0.20

0.0

1.3

—

3.08

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.25

0.19

1.4

1.6

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

142

1.20

0.16

1.4

1.8

103.91

98.75

pmol/l

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

333

0.84

0.10

11.4

9.0

94.67

82.96

ml/min/173m2

2.48

263

(40768797) Stomach Pathology biopsy report

1.18

0.10

1.0

1.1

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

0.84

0.08

1.7

1.5

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

341

1.16

0.08

4.2

4.6

1.66

1.84

mu/l

0.57

312

(3037467) Urinalysis macro (dipstick) panel - Urine

241

1.09

0.04

4.7

3.7

—

(3013512) EKG study

1.11

0.03

2.7

3.5

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

158

0.92

0.03

2.3

2.8

71.44

89.27

ug/l

0.50

148

(3015736) pH of Urine

127

1.03

0.00

1.9

3.4

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

115

0.94

0.00

2.1

2.8

19.27

30.79

u/l

2.93

108

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

0.92

0.00

1.0

1.8

1.36

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

0.0

1.0

—

(3011985) Renin [Units/volume] in Plasma

0.00

0.0

1.0

—

12.26

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

2.0

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

2.4

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

0.0

1.8

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.0

1.3

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.0

1.7

—

56.50

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.0

1.0

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.0

1.3

—

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

4.12

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.0

1.4

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

1.0

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

0.00

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.1

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.9

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.2

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.0

1.4

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.2

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.4

—

(3024928) Oxygen saturation in Venous blood

0.00

0.0

4.8

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.2

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.0

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.0

1.3

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

1.3

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.0

1.3

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.0

1.0

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.7

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.3

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.2

—

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.4

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

1.67

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

1.4

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

0.0

1.0

—

212.40

—

(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.2

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.0

1.0

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

0.0

1.0

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.2

—

(1616796) Gas panel - Central venous blood

0.00

0.0

1.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.04

0.00

2.0

1.7

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.3

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_MESOTHELIAL_EXALLC – Benign neoplasm of mesothelial tissue

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Benign neoplasm of mesothelial tissue

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Relationships between endpoints