info icon

This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Squamous cell neoplasms and carcinoma of rectum, excluding all cancers (controls excluding all cancers)

C3_RECTUM_SQUAM_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C19|C20
  • Cancer registry: Morphology ICD-O-3 8070
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

37

4. Check minimum number of events

None

37

5. Include endpoints

None

37

6. Filter based on genotype QC (FinnGen only)

37

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Squamous cell neoplasms and carcinoma of rectum, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 37 30 7
Unadjusted period prevalence (%) 0.01 0.01 0.00
Median age at first event (years) 62.27 60.13 71.42

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3022145) Colonoscopy Study observation
24
29
21.71
20.98
2.8
1.2
—
—
—
0
0
(4035726)
17
8
37.48
13.60
1.4
1.0
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
19
57
5.80
6.53
6.0
3.8
—
—
—
0
0
(3012095) Magnesium [Moles/volume] in Serum or Plasma
16
41
6.11
6.53
2.0
1.8
mmol/l
0.8
0.8
0.94
16
36
(40768804) Tissue Pathology biopsy report
27
110
6.38
6.53
3.6
1.5
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
28
127
5.93
5.84
9.1
3.9
g/l
35.7
36.1
0.15
28
120
(3015377) Calcium [Moles/volume] in Serum or Plasma
22
91
4.50
4.81
8.4
2.0
mmol/l
2.3
2.4
0.55
22
76
(40758558) Short blood count panel - Blood
18
64
4.53
4.80
10.1
4.4
—
—
—
0
0
(3002256) Pathology report gross observation
11
32
4.47
3.66
2.0
1.1
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
16
62
3.78
3.64
3.4
3.4
%
101.1
93.6
0.48
16
62
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
13
45
3.91
3.44
2.5
2.8
e6/l
2.7
5.3
—
7
24
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
20
93
3.50
3.42
3.7
3.0
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
28
164
3.90
3.39
10.2
3.3
umol/l
7.9
10.0
2.55
28
150
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
7
11
7.54
3.35
6.1
6.9
mmol/l
24.7
26.0
—
7
11
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
8
16
6.05
3.26
1.0
1.4
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
15
62
3.39
3.02
2.4
1.9
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
17
78
3.18
2.87
3.7
2.8
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
22
123
2.95
2.56
5.8
3.7
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
19
100
2.85
2.44
5.3
6.7
inr
1.0
1.2
—
5
29
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
12
51
3.00
2.23
5.0
2.0
mmol/l
2.5
2.4
0.32
12
39
(3044640) Blood type and Crossmatch panel - Blood
16
81
2.72
2.16
2.9
1.9
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
6
16
4.26
2.02
1.0
1.3
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
12
55
2.75
1.92
2.1
2.5
e6/l
0.2
1.2
—
6
33
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
7
23
3.50
1.91
1.7
1.9
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
7
23
3.50
1.91
1.7
1.9
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
29
210
2.76
1.87
5.4
4.0
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
5
13
4.27
1.77
6.0
8.7
%
97.4
93.4
—
5
13
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
5
13
4.27
1.77
9.4
7.8
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
19
115
2.34
1.69
17.2
8.2
e9/l
0.0
0.0
0.00
13
92
(3019198) Lymphocytes [#/volume] in Blood
22
142
2.35
1.69
3.7
5.3
e9/l
1.3
1.8
2.59
17
129
(3006315) Basophils [#/volume] in Blood
22
142
2.35
1.69
3.4
5.3
e9/l
0.0
0.0
2.90
16
126
(3001604) Monocytes [#/volume] in Blood
22
142
2.35
1.69
3.4
5.2
e9/l
0.5
0.5
0.16
16
126
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
5
14
3.95
1.67
6.0
7.9
%
0.9
1.7
—
5
14
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
5
14
3.95
1.67
1.0
1.1
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
5
14
3.95
1.67
6.0
7.9
%
0.4
0.8
—
5
14
(42870588) Differential panel, method unspecified - Blood
17
99
2.33
1.64
5.0
5.2
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
7
27
2.95
1.60
1.3
1.5
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
22
147
2.22
1.50
4.2
5.3
e9/l
0.1
0.2
1.76
17
131
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
19
121
2.17
1.44
2.2
1.9
pmol/l
87.1
97.1
—
10
45
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
13
71
2.28
1.42
1.9
1.3
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
8
34
2.72
1.39
2.4
1.8
—
—
—
0
0
(3002173) Hemoglobin [Mass/volume] in Arterial blood
6
24
2.78
1.36
8.3
6.8
g/l
112.7
123.8
—
6
24
(3000492) Spirometry study
5
19
2.88
1.26
1.0
1.2
—
—
—
0
0
(3000991) Gas panel - Venous blood
5
19
2.88
1.26
6.4
7.8
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
7
33
2.38
1.13
1.1
1.5
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
21
2.59
1.13
1.6
2.3
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
11
64
2.02
0.99
1.3
1.3
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
6
31
2.11
0.89
8.3
6.2
mmol/l
-0.0
2.2
—
6
25
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
15
102
1.79
0.85
4.9
2.1
u/l
59.5
56.8
0.13
15
93
(40760892) CBC W Ordered Manual Differential panel - Blood
9
54
1.88
0.83
5.0
4.4
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
27
0.00
0.81
0.0
1.1
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
26
301
0.54
0.79
3.7
6.2
mmol/mol
36.7
40.4
2.56
21
282
(3048689) Calprotectin [Mass/mass] in Stool
7
41
1.87
0.75
1.3
1.6
ug/g
92.9
109.0
—
7
33
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
26
2.06
0.73
1.4
2.2
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
5
30
1.77
0.64
1.0
1.4
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
0
19
0.00
0.62
0.0
1.2
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
29
254
1.65
0.58
33.6
14.1
%
13.8
13.6
0.48
29
248
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
14
104
1.56
0.53
2.6
2.8
u/l
24.1
29.4
0.76
14
97
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
16
0.00
0.42
0.0
1.2
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
18
0.00
0.41
0.0
1.1
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
32
292
1.71
0.41
23.0
12.6
%
37.7
39.6
1.35
25
211
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
20
171
1.37
0.34
2.8
2.7
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
30
316
0.73
0.33
3.7
4.9
mmol/l
5.7
5.9
0.99
25
291
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
9
74
1.28
0.28
1.4
1.8
mg/l
3.6
0.7
—
9
65
(3013826) Glucose [Moles/volume] in Serum or Plasma
19
167
1.28
0.24
6.6
4.0
mmol/l
6.3
6.7
0.72
19
152
(3020891) Body temperature
0
11
0.00
0.22
0.0
3.3
—
—
—
0
0
(1002224) Polysomnography panel
0
11
0.00
0.22
0.0
1.1
—
—
—
0
0
(3018405) Lactate [Moles/volume] in Arterial blood
0
11
0.00
0.22
0.0
3.6
—
1.2
—
0
11
(3004616) Nuclear Ab [Presence] in Serum
0
11
0.00
0.22
0.0
1.1
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
0
10
0.00
0.22
0.0
1.1
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
10
0.00
0.22
0.0
1.0
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
10
0.00
0.22
0.0
1.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3020961) Endomysium IgA Ab [Titer] in Serum
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
6
52
1.18
0.20
1.7
1.3
—
—
—
0
0
(3013512) EKG study
10
83
1.28
0.18
3.4
3.6
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
28
293
0.82
0.17
4.7
5.0
mu/l
2.0
1.9
0.07
23
268
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
12
103
1.24
0.16
1.2
2.0
u/l
96.0
115.9
0.24
12
97
(3041096) Erythrocytes [Presence] in Urine by Automated
10
84
1.26
0.16
4.2
3.7
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
9
104
0.82
0.15
2.0
3.0
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
6
72
0.80
0.08
1.3
1.2
g/l
2.0
2.4
—
6
38
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
12
129
0.90
0.04
2.6
2.3
nmol/l
74.7
79.1
0.21
12
115
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
12
113
1.09
0.02
3.7
4.0
—
—
—
0
0
(3015736) pH of Urine
10
106
0.92
0.01
2.6
3.6
—
—
—
0
0
(3044889) 12 lead EKG panel
23
225
1.06
0.00
4.1
3.6
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
2.7
—
8.8
—
0
6
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
6
64
0.93
0.00
2.7
3.4
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
0
6
0.00
0.00
0.0
3.5
—
—
—
0
0
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
8
80
1.00
0.00
1.4
2.4
umol/l
30991.3
11558.1
—
8
67
(3035285) Chloride [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
2.3
—
106.2
—
0
6
(3022313) Gas panel - Capillary blood
0
6
0.00
0.00
0.0
6.7
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
9
94
0.94
0.00
4.7
2.9
—
—
—
0
0
(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
2.8
—
0
6
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
2.3
—
4.0
—
0
6
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
2.7
—
1.5
—
0
6
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
0
7
0.00
-0.00
0.0
5.0
—
25.1
—
0
7
(3044290) Cell count panel - Cerebral spinal fluid
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
9
0.00
-0.00
0.0
1.1
—
66.8
—
0
9
(4027681)
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_RECTUM_SQUAM_EXALLC – Squamous cell neoplasms and carcinoma of rectum, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).