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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Squamous cell neoplasms and carcinoma of rectum, excluding all cancers (controls excluding all cancers)

C3_RECTUM_SQUAM_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C19|C20
  • Cancer registry: Morphology ICD-O-3 8070
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

37

4. Check minimum number of events

None

37

5. Include endpoints

None

37

6. Filter based on genotype QC (FinnGen only)

37

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Squamous cell neoplasms and carcinoma of rectum, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 37 30 7
Unadjusted period prevalence (%) 0.01 0.01 0.00
Median age at first event (years) 62.27 60.13 71.42

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
24
29
21.71
20.98
2.8
1.2
—
—
—
0
0
17
8
37.48
13.60
1.4
1.0
—
—
—
0
0
19
57
5.80
6.53
6.0
3.8
—
—
—
0
0
16
41
6.11
6.53
2.0
1.8
0.8
0.8
mmol/l
0.94
16
36
27
110
6.38
6.53
3.6
1.5
—
—
—
0
0
28
127
5.93
5.84
9.1
3.9
35.7
36.1
g/l
0.15
28
120
22
91
4.50
4.81
8.4
2.0
2.3
2.4
mmol/l
0.55
22
76
18
64
4.53
4.80
10.1
4.4
—
—
—
0
0
11
32
4.47
3.66
2.0
1.1
—
—
—
0
0
16
62
3.78
3.64
3.4
3.4
101.1
93.6
%
0.48
16
62
28
164
3.90
3.39
10.2
3.3
7.9
10.0
umol/l
2.55
28
150
7
11
7.54
3.35
6.1
6.9
24.7
26.0
mmol/l
—
7
11
17
78
3.18
2.87
3.7
2.8
—
—
—
0
0
19
100
2.85
2.44
5.3
6.7
1.0
1.2
inr
—
5
29
12
51
3.00
2.23
5.0
2.0
2.5
2.4
mmol/l
0.32
12
39
16
81
2.72
2.16
2.9
1.9
—
—
—
0
0
6
16
4.26
2.02
1.0
1.3
—
—
—
0
0
29
210
2.76
1.87
5.4
4.0
—
—
—
0
0
5
13
4.27
1.77
6.0
8.7
97.4
93.4
%
—
5
13
19
115
2.34
1.69
17.2
8.2
0.0
0.0
e9/l
0.00
13
92
22
142
2.35
1.69
3.7
5.3
1.3
1.8
e9/l
2.59
17
129
22
142
2.35
1.69
3.4
5.3
0.0
0.0
e9/l
2.90
16
126
22
142
2.35
1.69
3.4
5.2
0.5
0.5
e9/l
0.16
16
126
5
14
3.95
1.67
6.0
7.9
0.9
1.7
%
—
5
14
5
14
3.95
1.67
6.0
7.9
0.4
0.8
%
—
5
14
17
99
2.33
1.64
5.0
5.2
—
—
—
0
0
7
27
2.95
1.60
1.3
1.5
—
—
—
0
0
22
147
2.22
1.50
4.2
5.3
0.1
0.2
e9/l
1.76
17
131
19
121
2.17
1.44
2.2
1.9
87.1
97.1
pmol/l
—
10
45
6
24
2.78
1.36
8.3
6.8
112.7
123.8
g/l
—
6
24
5
19
2.88
1.26
1.0
1.2
—
—
—
0
0
5
19
2.88
1.26
6.4
7.8
—
—
—
0
0
7
33
2.38
1.13
1.1
1.5
—
—
—
0
0
5
21
2.59
1.13
1.6
2.3
—
—
—
0
0
11
64
2.02
0.99
1.3
1.3
—
—
—
0
0
6
31
2.11
0.89
8.3
6.2
-0.0
2.2
mmol/l
—
6
25
15
102
1.79
0.85
4.9
2.1
59.5
56.8
u/l
0.13
15
93
9
54
1.88
0.83
5.0
4.4
—
—
—
0
0
0
27
0.00
0.81
0.0
1.1
—
—
—
0
0
26
301
0.54
0.79
3.7
6.2
36.7
40.4
mmol/mol
2.56
21
282
7
41
1.87
0.75
1.3
1.6
92.9
109.0
ug/g
—
7
33
5
30
1.77
0.64
1.0
1.4
—
—
—
0
0
29
254
1.65
0.58
33.6
14.1
13.8
13.6
%
0.48
29
248
32
292
1.71
0.41
23.0
12.6
37.7
39.6
%
1.35
25
211
30
316
0.73
0.33
3.7
4.9
5.7
5.9
mmol/l
0.99
25
291
9
74
1.28
0.28
1.4
1.8
3.6
0.7
mg/l
—
9
65
19
167
1.28
0.24
6.6
4.0
6.3
6.7
mmol/l
0.72
19
152
0
11
0.00
0.22
0.0
3.3
—
—
—
0
0
0
11
0.00
0.22
0.0
1.1
—
—
—
0
0
0
11
0.00
0.22
0.0
3.6
—
1.2
—
0
11
0
11
0.00
0.22
0.0
1.1
—
—
—
0
0
0
10
0.00
0.22
0.0
1.1
—
—
—
0
0
0
10
0.00
0.22
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
10
83
1.28
0.18
3.4
3.6
—
—
—
0
0
28
293
0.82
0.17
4.7
5.0
2.0
1.9
mu/l
0.07
23
268
12
103
1.24
0.16
1.2
2.0
96.0
115.9
u/l
0.24
12
97
10
84
1.26
0.16
4.2
3.7
—
—
—
0
0
9
104
0.82
0.15
2.0
3.0
—
—
—
0
0
6
72
0.80
0.08
1.3
1.2
2.0
2.4
g/l
—
6
38
10
106
0.92
0.01
2.6
3.6
—
—
—
0
0
23
225
1.06
0.00
4.1
3.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.7
—
8.8
—
0
6
6
64
0.93
0.00
2.7
3.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
3.5
—
—
—
0
0
8
80
1.00
0.00
1.4
2.4
30991.3
11558.1
umol/l
—
8
67
0
6
0.00
0.00
0.0
2.3
—
106.2
—
0
6
0
6
0.00
0.00
0.0
6.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
9
94
0.94
0.00
4.7
2.9
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
4.0
—
0
6
0
6
0.00
0.00
0.0
2.7
—
1.5
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_RECTUM_SQUAM_EXALLC – Squamous cell neoplasms and carcinoma of rectum, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).