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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Carcinoma in situ of anus and anal canal

Endpoint Browser

CD2_INSITU_ANUS_ANAL_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

  • not C3_ANUS_ANALCANAL
-

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D01.3&
  • Hospital discharge: ICD-9 — 230[5-6]
  • Cause of death: ICD-10 — D01.3&
  • Cause of death: ICD-9 — 230[5-6]
  • Cancer registry: Topography ICD-O-3 — C21
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 2

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D01
Name in latin
Carcinoma in situ laryngis

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population - - -
Only index persons - - -
Unadjusted period prevalence (%)
Whole population - - -
Only index persons - - -
Median age at first event (years)
Whole population - - -
Only index persons - - -

-FinnGen-

Key figures

All Female Male
Number of individuals 33 20 13
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 63.32 61.93 65.45

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
18
18
20.80
17.44
1.7
1.0
—
—
—
0
0
12
5
36.13
9.74
1.3
1.0
—
—
—
0
0
22
74
6.92
6.91
5.1
1.7
—
—
—
0
0
19
57
6.50
6.70
17.1
4.9
—
—
—
0
0
21
80
5.47
5.40
4.0
2.6
23.5
108.2
e6/l
0.61
16
60
12
29
5.93
5.13
3.4
1.3
—
—
—
0
0
22
92
5.17
4.93
4.5
3.0
132.2
77.5
e6/l
0.23
16
64
19
71
4.95
4.89
3.9
2.6
—
—
—
0
0
19
75
4.61
4.48
3.7
2.2
—
—
—
0
0
19
76
4.54
4.38
4.2
2.5
1.1
0.4
e6/l
0.52
14
55
16
61
4.15
3.83
7.9
4.1
—
—
—
0
0
10
27
4.88
3.67
1.9
1.6
—
—
—
0
0
20
99
3.59
3.13
17.1
7.5
0.0
0.0
e9/l
0.00
14
74
9
25
4.54
2.83
8.0
8.0
103.4
104.6
mmol/l
—
9
25
10
33
3.91
2.80
2.6
2.1
—
—
—
0
0
13
58
3.05
2.27
2.5
4.2
—
—
—
0
0
10
38
3.34
2.25
3.7
1.9
—
—
—
0
0
17
92
2.75
2.06
12.7
4.9
—
—
—
0
0
28
207
3.32
1.92
6.4
4.1
15.5
10.9
mm/h
0.73
28
193
15
79
2.65
1.88
4.0
3.1
—
—
—
0
0
26
187
2.83
1.81
6.4
4.0
—
—
—
0
0
14
74
2.55
1.72
5.8
1.8
2.3
2.4
mmol/l
0.16
14
59
19
117
2.47
1.69
1.9
2.0
98.4
97.0
pmol/l
—
10
53
8
35
2.69
1.39
1.7
1.5
—
—
—
0
0
5
20
2.76
1.19
9.6
10.5
—
—
—
0
0
24
183
2.14
1.18
4.5
3.7
—
—
—
0
0
17
117
1.93
0.99
4.3
2.6
124.1
100.9
ug/l
0.40
17
108
11
68
1.93
0.85
1.4
1.2
—
—
—
0
0
11
68
1.93
0.85
5.5
1.8
390.3
351.3
umol/l
0.48
11
61
0
22
0.00
0.62
0.0
3.0
—
4.2
—
0
16
24
267
0.63
0.59
5.1
4.8
4.6
4.5
mmol/l
0.09
24
242
27
238
1.74
0.52
46.4
16.6
331.1
332.2
g/l
0.29
27
238
7
48
1.58
0.51
3.0
8.0
—
—
—
0
0
5
31
1.72
0.45
1.0
1.1
—
—
—
0
0
18
210
0.69
0.40
7.0
3.9
14.3
14.8
pmol/l
0.53
18
189
8
100
0.74
0.26
2.3
2.0
155.0
216.2
u/l
—
8
95
0
11
0.00
0.22
0.0
1.4
—
1.1
—
0
11
0
11
0.00
0.22
0.0
1.1
—
—
—
0
0
0
11
0.00
0.22
0.0
1.4
—
0.2
—
0
11
6
74
0.77
0.18
3.7
3.1
—
—
—
0
0
7
85
0.78
0.17
5.7
3.7
—
—
—
0
0
12
103
1.26
0.17
3.5
3.7
—
—
—
0
0
7
64
1.12
0.09
1.3
1.6
21.0
19.4
nmol/l
—
7
55
27
261
1.19
0.08
7.1
6.5
43.7
40.6
mmol/mol
0.68
27
242
8
82
0.97
0.00
2.6
3.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.9
—
76.4
—
0
8
0
6
0.00
0.00
0.0
5.3
—
3.5
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
60.2
—
0
5
0
5
0.00
0.00
0.0
1.2
—
5.8
—
0
5
0
7
0.00
0.00
0.0
5.0
—
1.2
—
0
7
9
92
0.97
0.00
5.6
2.9
65.9
74.0
mg/l
—
9
53
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.6
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_INSITU_ANUS_ANAL_EXALLC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_INSITU_ANUS_ANAL_EXALLC.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_ANUS_ANAL_EXALLC – Carcinoma in situ of anus and anal canal

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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