Embolism and thrombosis of abdominal aorta

I9_EMBTHROAOR

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I74.0
  • Hospital discharge: ICD-9 4440A
  • Hospital discharge: ICD-8 44400
  • Hospital discharge: excluded ICD-9 4440
  • Cause of death: ICD-10 I74.0
  • Cause of death: ICD-9 4440A
  • Cause of death: ICD-8 44400
  • Cause of death: excluded ICD-9 4440

2 out of 7 registries used, show all original rules.

72

4. Check minimum number of events

None

72

5. Include endpoints

None

72

6. Filter based on genotype QC (FinnGen only)

67

Control definitions (FinnGen only)

Control exclude
I9_DOAAC

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF12
Parent code in ICD-10
I74
Name in latin
Embolia aortae abdominalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 67 23 44
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 67.21 62.34 69.76

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
72
Matched controls
720
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I74.0
ICD-10 Finland
Embolism and thrombosis of abdominal aorta
+∞
89.2
66
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
326.2
51.7
47
*
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
+∞
16.2
15
*
PDH54
NOMESCO Finland
Bypass from aorta to bilateral femoral arteries
+∞
11.8
11
*
I74.3
ICD-10 Finland
Embolism and thrombosis of arteries of lower extremities
+∞
11.8
11
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
11.6
10.7
20
23
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
114.4
9.7
10
*
PDE05
NOMESCO Finland
Thrombectomy or embolectomy of infrarenal abdominal aorta
+∞
8.5
8
*
NGM10
NOMESCO Finland
Fasciotomy of of knee or lower leg
+∞
8.5
8
*
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
28.6
7.8
10
*
TPH07
NOMESCO Finland
Cathetrisation of artery
7.2
7.8
19
34
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.4
7.7
25
77
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
+∞
7.4
7
*
I74.1
ICD-10 Finland
Embolism and thrombosis of other and unspecified parts of aorta
+∞
7.4
7
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.8
7.2
35
143
ZXD05
NOMESCO Finland
Urgent procedure
3.8
7.0
33
132
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
12.7
6.6
11
10
PDQ05
NOMESCO Finland
Insertion of endovascular graft into infrarenal abdominal aorta
+∞
6.3
6
*
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
+∞
6.3
6
*
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
+∞
6.3
6
*
PGH47
NOMESCO Finland
Bypass from femoral to contralateral femoral artery
+∞
6.3
6
*
44400
ICD-8 Finland
Arterial embolism and thrombosis, Of abdominal aorta
+∞
6.3
6
*
4402A
ICD-9 Finland
Atherosclerosis, Of native arteries of the extremities
+∞
6.3
6
*
PEH56
NOMESCO Finland
Bypass from femoral to popliteal artery above knee
+∞
6.3
6
*
N05BA01
ATC
diazepam; systemic, rectal
4.7
6.1
16
41

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
19
43
5.64
8.49
2.2
1.5
—
—
—
0
0
11
18
7.00
4.82
3.6
6.4
24.17
22.94
mmol/l
0.53
11
18
8
9
9.81
4.40
3.9
2.2
—
—
—
0
0
11
22
5.70
4.20
22.8
6.6
—
—
—
0
0
19
78
2.95
3.58
3.3
3.6
0.84
0.81
mmol/l
1.01
19
73
13
38
3.94
3.54
10.1
8.2
—
—
—
0
0
13
41
3.64
3.27
18.3
2.9
—
—
—
0
0
28
148
2.46
3.20
3.8
3.8
28.32
7.20
mg/mmol
0.83
19
98
28
152
2.38
2.99
9.1
4.0
—
—
—
0
0
11
35
3.52
2.79
8.5
6.4
93.72
94.03
%
0.09
11
35
11
37
3.32
2.63
1.6
1.4
—
—
—
0
0
25
137
2.26
2.56
3.8
3.2
158.64
487.88
mg/l
0.33
17
92
10
39
2.81
2.04
1.6
1.5
—
—
—
0
0
9
35
2.79
1.88
10.1
5.5
1.76
1.35
%
—
9
35
14
68
2.31
1.85
13.7
5.0
105.50
103.72
mmol/l
0.70
14
68
38
269
1.87
1.82
33.7
13.5
1.50
1.38
inr
—
6
83
30
198
1.88
1.78
6.3
6.4
—
—
—
0
0
20
115
2.02
1.76
3.4
2.7
2.93
3.48
e6/l
0.21
20
102
7
25
2.99
1.70
5.3
2.7
1.03
1.16
mmol/l
—
7
25
37
269
1.77
1.56
16.6
5.9
1.18
1.21
mmol/l
1.65
30
223
7
28
2.66
1.49
10.1
3.4
—
—
—
0
0
9
43
2.25
1.36
1.9
1.7
—
—
—
0
0
6
24
2.63
1.33
2.3
3.2
—
—
—
0
0
8
35
2.44
1.32
11.3
6.1
0.71
0.75
%
—
8
35
26
180
1.70
1.25
4.3
2.9
—
—
—
0
0
19
120
1.79
1.25
4.9
3.3
—
—
—
0
0
7
30
2.47
1.16
2.0
1.5
—
—
—
0
0
21
140
1.71
1.14
5.0
3.0
—
—
—
0
0
9
46
2.09
1.08
1.2
3.5
73.44
68.77
e9/l
—
9
36
5
22
2.36
1.05
4.4
2.2
—
—
—
0
0
5
22
2.36
1.05
7.0
2.5
4.34
3.90
mmol/l
—
5
22
12
70
1.86
1.00
4.6
1.5
—
—
—
0
0
8
42
2.02
0.92
1.1
2.5
66.33
67.23
g/l
—
8
36
6
33
1.89
0.81
7.3
2.5
0.55
0.71
%
—
6
33
5
24
2.16
0.76
1.2
1.5
—
—
—
0
0
46
518
0.69
0.72
61.2
22.4
36.86
39.08
%
1.13
40
484
22
166
1.47
0.70
4.0
2.2
—
—
—
0
0
10
62
1.71
0.69
2.7
1.2
—
—
—
0
0
41
467
0.72
0.64
6.2
5.1
6.25
6.07
mmol/l
0.40
35
424
31
369
0.72
0.64
58.0
19.4
325.81
332.41
g/l
2.52
31
364
27
216
1.40
0.62
2.3
1.9
94.78
95.85
pmol/l
0.04
18
104
5
30
1.71
0.62
1.0
1.5
1.89
1.67
g/l
—
5
24
10
147
0.63
0.62
3.9
3.2
—
—
—
0
0
45
503
0.72
0.61
49.6
18.4
114.51
83.03
umol/l
1.42
45
503
6
34
1.83
0.60
7.3
2.5
1.97
1.30
%
—
6
34
6
38
1.63
0.56
1.2
2.2
—
—
—
0
0
6
39
1.59
0.54
5.7
4.0
—
—
—
0
0
6
39
1.59
0.54
2.8
1.7
376.00
419.36
nmol/l
—
6
33
13
175
0.69
0.53
3.3
2.3
—
—
—
0
0
7
45
1.61
0.51
5.0
3.3
—
—
—
0
0
29
244
1.32
0.47
7.7
3.9
36.54
40.22
ng/l
0.15
24
195
30
256
1.29
0.43
7.4
5.5
0.00
0.00
estimate
—
6
46
30
257
1.29
0.42
6.3
4.0
0.00
0.00
estimate
—
5
43
0
15
0.00
0.41
0.0
1.9
—
4.05
—
0
15
0
15
0.00
0.41
0.0
1.9
—
106.67
—
0
15
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
0
16
0.00
0.41
0.0
3.9
—
35.62
—
0
9
30
258
1.28
0.40
6.1
4.0
0.00
0.00
estimate
—
6
47
5
35
1.46
0.40
2.0
1.5
—
—
—
0
0
7
54
1.33
0.31
4.9
4.1
—
—
—
0
0
46
494
0.81
0.31
40.5
14.4
—
—
—
0
0
37
336
1.21
0.28
8.4
4.6
—
536.89
—
0
9
5
38
1.34
0.24
2.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
20
176
1.19
0.20
7.4
4.4
—
—
—
0
0
7
58
1.23
0.19
3.4
4.2
9.31
133.66
ug/l
—
7
47
13
111
1.21
0.17
6.8
6.4
—
—
—
0
0
10
118
0.82
0.15
1.3
1.4
—
—
—
0
0
10
114
0.86
0.10
2.0
3.2
2.50
2.47
mmol/l
—
10
95
5
43
1.17
0.10
3.8
1.4
—
—
—
0
0
13
140
0.91
0.05
5.5
4.2
—
—
—
0
0
46
470
0.94
0.04
45.9
15.4
38.91
26.79
mg/l
1.31
41
384
35
341
1.05
0.03
8.0
4.3
—
—
—
0
0
42
426
0.97
0.00
5.8
4.7
1.62
2.03
mu/l
1.44
36
376
21
206
1.03
0.00
25.2
10.1
0.00
0.01
e9/l
0.51
15
169
35
354
0.98
0.00
7.6
4.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.8
—
5.47
—
0
6
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
311.18
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.3
—
—
—
0
0
6
66
0.90
-0.00
1.7
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.4
—
31.75
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
29.60
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: I9_EMBTHROAOR – Embolism and thrombosis of abdominal aorta

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).