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Embolism and thrombosis of abdominal aorta

MESH Endpoint Browser PheWeb

I9_EMBTHROAOR

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I74.0
  • Hospital discharge: ICD-9 — 4440A
  • Hospital discharge: ICD-8 — 44400
  • Hospital discharge: excluded ICD-9 — 4440
  • Cause of death: ICD-10 — I74.0
  • Cause of death: ICD-9 — 4440A
  • Cause of death: ICD-8 — 44400
  • Cause of death: excluded ICD-9 — 4440

2 out of 7 registries used, show all original rules.

71

4. Check minimum number of events

None

71

5. Include endpoints

None

71

6. Filter based on genotype QC (FinnGen only)

71

Control definitions (FinnGen only)

Control exclude
I9_DOAAC

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF12
Parent code in ICD-10
I74
Name in latin
Embolia aortae abdominalis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 71 25 46
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 65.98 62.34 67.95

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

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CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
69
Matched controls
689
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I74.0
ICD-10 Finland
Embolism and thrombosis of abdominal aorta
+∞
75.4
58
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
153.7
40.6
40
6
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
+∞
14.0
13
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
21.5
12.5
18
11
PDH54
NOMESCO Finland
Bypass from aorta to bilateral femoral arteries
+∞
10.7
10
*
4402A
ICD-9 Finland
Atherosclerosis, Of native arteries of the extremities
+∞
9.6
9
*
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
+∞
9.6
9
*
I74.3
ICD-10 Finland
Embolism and thrombosis of arteries of lower extremities
+∞
9.6
9
*
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
+∞
7.4
7
*
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
+∞
7.4
7
*
4440A
ICD-9 Finland
Arterial embolism and thrombosis, Of abdominal aorta
+∞
7.4
7
*
I74.1
ICD-10 Finland
Embolism and thrombosis of other and unspecified parts of aorta
+∞
6.3
6
*
C01DA14
ATC
isosorbide mononitrate; oral
3.9
6.0
28
102

Mortality – FinRegistry

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This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

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Index endpoint: I9_EMBTHROAOR – Embolism and thrombosis of abdominal aorta

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).