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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_ENDOCRINE_NAS_EXALLC for full statistics.

Malignant neoplasm of other endocrine glands and related structures

DOID Endpoint Browser

C3_ENDOCRINE_NAS

endocrine neoplasm: A benign or malignant neoplasm arising from the epithelial cells of an endocrine organ. Representative examples include pituitary gland adenoma, pituitary gland carcinoma, thyroid gland carcinoma, carcinoid tumor, and neuroendocrine carcinoma.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C75
  • Cause of death: ICD-9 — 194[1-9]
  • Cause of death: ICD-8 — 194[1-9]
  • Cancer registry: Topography ICD-O-3 — C75
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

51

4. Check minimum number of events

None

51

5. Include endpoints

None

51

6. Filter based on genotype QC (FinnGen only)

51

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Similar endpoints

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Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 51 27 24
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 50.19 49.99 50.42

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
23
36
10.82
15.63
1.4
1.1
—
—
—
0
0
37
109
9.72
14.12
18.8
4.7
7.4
7.4
ph
0.02
16
15
24
53
7.66
11.72
12.7
6.2
1.0
1.0
mmol/l
0.36
24
48
44
187
10.82
11.35
22.5
7.8
1.2
1.2
mmol/l
0.60
28
163
29
122
4.19
6.00
3.3
2.1
—
—
—
0
0
33
156
4.16
5.71
2.0
2.0
—
—
—
0
0
13
33
4.94
5.07
2.7
3.8
—
—
—
0
0
30
153
3.33
4.25
13.3
5.0
1.3
1.2
inr
0.16
13
50
10
24
4.94
4.10
12.0
11.4
95.7
91.7
%
—
10
24
23
107
3.09
3.70
6.8
3.8
—
—
—
0
0
20
94
2.86
3.07
3.2
2.6
6.0
5.8
e6/l
0.03
20
83
24
126
2.71
2.97
6.3
3.8
—
—
—
0
0
9
23
4.52
2.94
4.0
5.6
23.8
25.9
mmol/l
—
9
23
22
114
2.64
2.76
1.6
1.4
—
—
—
0
0
5
7
7.75
2.60
7.8
1.4
3.5
2.3
u/ml
—
5
7
8
21
4.31
2.58
1.0
1.3
—
—
—
0
0
11
41
3.15
2.46
1.3
1.2
—
—
—
0
0
35
243
2.40
2.17
9.3
4.2
6.5
7.0
mmol/l
1.06
35
224
10
38
3.03
2.15
17.1
10.6
—
—
—
0
0
20
111
2.32
2.08
4.3
2.9
—
—
—
0
0
20
111
2.32
2.08
11.4
5.8
—
—
—
0
0
17
88
2.40
2.05
3.4
3.2
428.5
562.4
mosm/kgh2o
2.54
17
75
15
74
2.45
2.00
2.4
1.6
1824.1
1145.6
nmol/l
—
9
55
5
11
4.91
1.99
5.4
1.0
4.6
5.2
kpa
—
5
11
5
11
4.91
1.99
5.4
1.0
8.2
8.6
kpa
—
5
11
12
54
2.60
1.91
8.5
2.5
17.7
23.2
%
1.06
12
44
12
56
2.49
1.78
7.8
2.5
2.3
2.4
g/l
0.23
12
48
5
13
4.14
1.76
5.0
1.2
—
—
—
0
0
10
43
2.65
1.73
1.2
1.6
—
—
—
0
0
13
65
2.34
1.66
7.3
2.3
12.0
14.4
umol/l
0.56
13
54
12
59
2.35
1.59
2.9
1.7
—
—
—
0
0
9
38
2.66
1.55
1.4
1.3
—
—
—
0
0
38
298
2.08
1.43
4.3
4.1
—
—
—
0
0
17
102
2.00
1.38
3.5
5.5
—
—
—
0
0
5
20
2.66
1.18
1.6
2.2
—
—
—
0
0
8
41
2.12
1.15
9.5
5.9
5.4
5.9
kpa
—
8
41
8
41
2.12
1.15
9.5
6.0
—
—
—
0
0
38
311
1.87
1.09
4.0
3.6
8.6
11.3
mm/h
1.20
38
285
5
22
2.41
1.06
1.0
2.7
—
—
—
0
0
7
36
2.09
1.01
14.3
4.1
—
—
—
0
0
34
274
1.72
0.98
4.3
3.5
—
—
—
0
0
18
122
1.73
0.98
3.2
3.2
99.3
71.6
mg/l
0.14
12
80
46
415
2.10
0.89
26.5
12.3
26.4
24.0
mg/l
0.21
41
326
16
109
1.68
0.84
2.6
3.7
0.0
0.0
estimate
0.00
11
39
14
92
1.72
0.83
2.9
2.3
—
—
—
0
0
32
374
0.61
0.83
46.6
15.5
327.9
333.1
g/l
2.09
32
374
18
132
1.56
0.70
4.0
4.4
18.1
10.0
mg/mmol
—
10
87
18
135
1.52
0.63
2.7
3.1
7.9
8.2
mmol/l
0.06
13
107
0
19
0.00
0.61
0.0
6.0
—
—
—
0
0
0
19
0.00
0.61
0.0
1.2
—
—
—
0
0
15
111
1.50
0.55
1.1
1.6
1.5
1.3
mmol/l
—
10
90
26
217
1.40
0.51
2.6
3.8
0.0
0.0
estimate
0.00
11
36
17
132
1.43
0.49
1.6
3.2
—
—
—
0
0
25
211
1.36
0.44
2.6
3.7
0.0
0.0
estimate
0.00
11
38
10
71
1.51
0.43
3.0
3.6
22.4
168.2
ng/l
—
10
56
0
15
0.00
0.42
0.0
1.5
—
—
—
0
0
0
15
0.00
0.42
0.0
1.5
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
212.7
—
0
7
5
35
1.47
0.40
6.8
4.1
8.3
4.4
kpa
—
5
35
6
46
1.34
0.34
1.2
1.3
—
362.9
—
0
14
6
46
1.34
0.34
1.2
1.3
—
—
—
0
0
24
214
1.23
0.24
3.3
5.5
0.0
0.0
estimate
0.00
11
38
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
3.1
—
—
—
0
0
0
10
0.00
0.21
0.0
3.1
—
4.0
—
0
10
0
10
0.00
0.21
0.0
3.1
—
107.3
—
0
10
6
47
1.31
0.21
4.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
4.0
—
7.9
—
0
13
0
13
0.00
0.21
0.0
4.0
—
1.6
—
0
13
14
119
1.24
0.20
3.8
4.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
2.5
—
—
—
0
0
9
77
1.20
0.17
3.9
1.6
—
—
—
0
0
39
372
1.21
0.15
7.3
6.1
40.1
40.0
mmol/mol
0.04
34
347
18
163
1.16
0.13
2.2
1.8
100.0
95.5
pmol/l
—
10
81
5
60
0.82
0.09
5.6
1.6
—
—
—
0
0
42
426
0.92
0.07
4.3
4.9
2.6
2.7
mmol/l
0.27
36
386
39
400
0.89
0.05
3.6
3.9
1.4
1.3
mmol/l
0.19
32
357
14
130
1.11
0.05
2.6
3.7
—
—
—
0
0
17
161
1.08
0.04
2.3
3.7
—
—
—
0
0
39
391
0.99
0.00
35.0
12.7
37.8
39.8
%
0.59
27
287
41
413
0.96
0.00
4.0
4.3
1.4
1.4
mmol/l
0.20
36
371
15
147
1.03
0.00
3.1
3.1
—
—
—
0
0
9
88
1.03
0.00
2.4
3.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
4.8
—
57.0
—
0
8
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
14.8
—
—
—
0
0
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
42
418
1.03
0.00
4.0
4.3
4.5
4.6
mmol/l
0.11
37
380
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
13.0
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
9.8
—
0
5
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: C3_ENDOCRINE_NAS – Malignant neoplasm of other endocrine glands and related structures

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).