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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_OROPHARYNG_EXALLC for full statistics.

Malignant neoplasm of oropharyng

C3_OROPHARYNG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C10
  • Cause of death: ICD-9 146
  • Cause of death: ICD-8 146
  • Cause of death: excluded ICD-9 1460A
  • Cancer registry: Topography ICD-O-3 C10
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

51

4. Check minimum number of events

None

51

5. Include endpoints

None

51

6. Filter based on genotype QC (FinnGen only)

51

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF12

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 51 14 37
Unadjusted period prevalence (%) 0.01 0.00 0.02
Median age at first event (years) 67.50 65.96 68.08

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
50
Matched controls
502
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
JDB10
NOMESCO Finland
Percutaneous gastrostomy
259.6
33.4
31
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
179.7
31.2
30
*
130
Kela drug reimbursment
Malignant tumour
42.7
27.5
38
34
R4190
NOMESCO Finland
Nutritional therapy
68.7
22.6
25
7
8070/3-C10.9
ICD-O-3
Squamous cell carcinoma, NOS, of oropharynx, NOS
+∞
21.4
19
*
C10.3
ICD-10 Finland
Malignant neoplasm: Posterior wall of oropharynx
+∞
18.9
17
*
N02AA05
ATC
oxycodone; systemic
19.4
18.7
33
45
WF002
NOMESCO Finland
Radical radiotherapy
26.4
18.7
27
21
A03FA01
ATC
metoclopramide; systemic, rectal
15.7
16.9
34
59
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
59.3
16.9
19
5
UJC01
NOMESCO Finland
Scopy of lower throat
208.5
15.4
15
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
14.2
13
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
14.2
13
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
85.6
12.3
13
*
A04AA01
ATC
ondansetron; systemic, rectal
16.8
11.2
18
16
C10.0
ICD-10 Finland
Malignant neoplasm: Vallecula
+∞
10.8
10
*
GBB00
NOMESCO Finland
Tracheostomy
51.3
10.5
12
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
20.7
10.3
15
10
C10.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of oropharynx
+∞
9.7
9
*
SAA03
NOMESCO Finland
Extended examination of mouth
6.9
9.4
34
117
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
12.2
9.3
17
20
ENA10
NOMESCO Finland
Biopsy of pharynx
+∞
8.6
8
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
8.6
8
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
17.0
8.4
13
10
EBA15
NOMESCO Finland
Extraction of large number of teeth
14.4
8.4
14
13
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
6.0
8.2
31
107
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
11.7
7.7
14
16
C01
ICD-10 Finland
Malignant neoplasm of base of tongue
93.4
7.6
8
*
H02AB02
ATC
dexamethasone; systemic
8.3
7.5
17
29
D10.9
ICD-10 Finland
Benign neoplasm: Pharynx, unspecified
+∞
7.5
7
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
7.5
7
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
+∞
7.5
7
*
C10.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of oropharynx
+∞
7.5
7
*
A06AD11
ATC
lactulose; oral
8.0
7.3
17
30
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
8.5
7.2
16
26
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
9.2
7.2
15
22
A02BC05
ATC
esomeprazole; systemic
5.0
6.8
34
149
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
8.8
6.6
14
21
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
79.6
6.6
7
*
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
31.0
6.4
8
*
8070/3-C10.3
ICD-O-3
Squamous cell carcinoma, NOS, of posterior wall of oropharynx
+∞
6.4
6
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
17.9
6.2
9
6

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
23
39
9.92
14.55
1.4
1.4
—
—
—
0
0
30
69
9.13
14.55
9.1
3.5
0.7
0.8
mmol/l
2.51
30
64
36
168
4.89
6.65
2.4
2.0
—
—
—
0
0
26
108
3.87
5.35
5.0
3.6
93.5
88.5
%
0.50
26
108
27
124
3.50
4.63
3.0
2.3
—
—
—
0
0
28
143
3.12
3.86
9.4
4.1
2.4
2.3
mmol/l
0.65
28
125
6
5
13.33
3.86
1.3
1.8
—
—
—
0
0
15
59
3.19
3.13
1.8
1.6
—
—
—
0
0
14
55
3.13
2.91
2.1
1.9
—
—
—
0
0
37
246
2.84
2.81
16.5
11.7
4.6
4.3
e9/l
0.32
32
209
23
125
2.53
2.59
4.3
4.8
—
—
—
0
0
17
80
2.69
2.54
5.4
3.1
2.5
2.4
mmol/l
1.47
17
67
35
239
2.48
2.32
11.7
7.1
9.5
12.1
umol/l
1.50
35
226
21
115
2.40
2.28
15.0
8.4
—
—
—
0
0
14
63
2.68
2.26
2.9
2.0
—
—
—
0
0
6
14
4.70
2.22
1.5
1.2
—
—
—
0
0
8
26
3.45
2.12
11.4
7.7
—
—
—
0
0
9
34
2.99
1.98
13.8
9.5
94.9
94.3
%
—
9
34
18
98
2.29
1.93
1.3
1.3
—
—
—
0
0
13
62
2.47
1.85
6.2
4.9
1.0
1.0
mmol/l
0.21
13
57
23
142
2.13
1.81
5.7
5.4
—
—
—
0
0
27
187
1.94
1.48
8.2
6.4
1.2
1.2
mmol/l
0.68
27
167
0
41
0.00
1.38
0.0
3.2
—
—
—
0
0
0
34
0.00
1.21
0.0
2.3
—
—
—
0
0
33
256
1.82
1.17
8.7
5.0
7.1
6.9
mmol/l
0.25
33
240
8
41
2.12
1.15
14.8
7.6
—
—
—
0
0
21
282
0.57
1.13
3.5
4.1
—
—
—
0
0
6
118
0.44
1.12
1.8
1.7
1.4
1.3
mmol/l
—
6
97
8
137
0.51
1.03
5.8
3.9
—
—
—
0
0
10
55
2.02
1.00
1.1
1.2
—
—
—
0
0
27
205
1.67
0.97
6.6
6.7
0.6
0.6
e9/l
0.16
20
174
27
207
1.65
0.92
6.6
6.7
0.0
0.0
e9/l
0.29
20
175
27
210
1.61
0.85
6.6
6.8
1.5
1.7
e9/l
0.56
19
185
27
212
1.58
0.81
6.6
6.9
0.2
0.2
e9/l
0.27
19
184
39
336
1.68
0.77
34.4
22.3
329.7
332.4
g/l
0.91
39
336
7
40
1.87
0.75
5.0
4.3
—
—
—
0
0
42
452
0.60
0.75
34.5
18.5
71.2
82.5
umol/l
2.56
42
452
5
27
1.94
0.70
5.0
4.3
—
0.9
—
0
7
5
86
0.54
0.63
1.0
1.8
735.6
433.3
pmol/l
—
5
75
23
278
0.69
0.59
3.3
4.4
—
24.9
—
0
7
41
444
0.61
0.57
19.5
14.1
—
—
—
0
0
41
372
1.52
0.49
32.5
16.0
37.7
40.4
%
2.28
33
247
11
147
0.68
0.46
2.7
2.8
—
—
—
0
0
5
32
1.62
0.43
19.0
6.8
29.4
24.8
mmol/l
—
5
32
5
33
1.57
0.42
5.4
4.3
—
1.3
—
0
13
0
16
0.00
0.42
0.0
1.4
—
—
—
0
0
0
16
0.00
0.42
0.0
4.4
—
—
—
0
0
12
154
0.71
0.39
3.0
4.1
—
—
—
0
0
10
129
0.72
0.33
2.5
3.0
—
—
—
0
0
14
166
0.78
0.25
3.9
3.3
2.6
39.1
e6/l
—
8
126
5
40
1.28
0.23
2.0
2.7
3.6
8.4
ug/l
—
5
35
0
11
0.00
0.21
0.0
2.5
—
8.1
—
0
11
0
11
0.00
0.21
0.0
2.5
—
3.4
—
0
5
0
11
0.00
0.21
0.0
2.5
—
5.0
—
0
11
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
1.3
—
0
10
0
10
0.00
0.21
0.0
1.8
—
105.5
—
0
10
0
10
0.00
0.21
0.0
2.6
—
17.8
—
0
5
0
12
0.00
0.21
0.0
2.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
16
138
1.23
0.21
4.1
2.5
36.9
55.0
u/l
2.48
16
133
0
14
0.00
0.20
0.0
22.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
33
314
1.14
0.11
3.5
4.1
—
—
—
0
0
17
156
1.13
0.09
1.8
1.9
93.1
84.1
pmol/l
—
7
73
5
48
1.05
0.09
1.4
1.7
—
—
—
0
0
21
196
1.12
0.09
9.5
10.2
0.0
0.0
e9/l
0.47
16
161
14
152
0.89
0.07
3.3
2.8
6.0
418.7
e6/l
—
8
122
11
100
1.13
0.06
2.3
4.3
—
—
—
0
0
14
131
1.09
0.04
2.1
2.2
93.4
328.8
u/l
1.05
14
124
36
351
1.09
0.04
34.9
19.4
14.1
13.8
%
0.45
36
344
13
138
0.92
0.03
3.5
2.6
—
—
—
0
0
14
141
0.99
0.00
3.3
2.6
0.4
0.5
e6/l
—
8
110
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
0.3
—
0
9
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
4.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
61.9
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
88.9
—
0
5
0
5
0.00
0.00
0.0
1.4
—
34.2
—
0
5
0
5
0.00
0.00
0.0
3.4
—
0.9
—
0
5
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
5.3
—
16.6
—
0
7
0
8
0.00
0.00
0.0
1.8
—
4.9
—
0
8
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
85
0.93
0.00
4.6
6.8
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
4.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
3.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_OROPHARYNG – Malignant neoplasm of oropharyng

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).