Gastric ulcer - Acute with haemorrhage, drug-induced

GASTRIC_ULCER_ACUTE_W_HAEMORRHAGE

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ATC codes for adverse effects of Drugs — ANY Hospital discharge: ICD-10 — K25.0# 1 out of 7 registries used, show all original rules.	66
4. Check minimum number of events None	66
5. Include endpoints None	66
6. Filter based on genotype QC (FinnGen only)	63

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: C
First used in FinnGen datafreeze: DF5

NAME	GASTRIC_ULCER_ACUTE_W_HAEMORRHAGE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC	ANY
HD_ICD_10	K250
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Gastric ulcer - Acute with haemorrhage, drug-induced based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (not available in FinRegistry).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	63	17	46
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	61.62	58.27	62.86

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
66: Matched controls
660

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

K25.0

ICD-10 Finland

Gastric ulcer, Acute with haemorrhage

+∞

84.6

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

6.5

13.1

133

UJD02

NOMESCO Finland

Gastroscopy

14.1

10.6

A02BC01

ATC

omeprazole; systemic

4.8

9.2

132

A02BC03

ATC

lansoprazole; oral

4.7

9.0

141

K92.0

ICD-10 Finland

Haematemesis

11.9

6.9

JDA32

NOMESCO Finland

Endoscopic injection in stomach or pylorus

77.0

6.5

K26.0

ICD-10 Finland

Duodenal ulcer, acute with haemorrhage

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

6.65

2.41

1.6

1.0

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.00

1.96

0.0

5.2

—

31.13

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.70

1.66

3.5

1.4

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

162

0.42

1.66

2.5

3.0

2.33

2.34

mmol/l

—

133

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

3.77

1.64

2.4

1.1

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

3.04

1.54

1.2

1.4

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

406

0.55

1.52

5.3

5.0

6.75

6.16

mmol/l

0.24

354

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.67

1.50

3.3

1.6

—

(3000492) Spirometry study

0.00

1.20

0.0

1.4

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

107

0.42

1.14

3.6

2.9

2.57

2.45

mmol/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

2.08

1.13

3.4

1.6

—

(3042936) Bacteria identified in Isolate by Culture

1.93

1.09

1.7

2.0

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.01

1.06

7.2

3.4

—

(3019060) Gas panel - Arterial blood

2.05

1.00

2.6

3.9

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

374

0.64

0.98

4.3

4.2

1.80

2.10

mu/l

0.84

316

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

405

0.67

0.81

5.3

2.25

2.50

mmol/l

0.91

358

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

284

0.66

0.78

3.6

3.4

14.86

15.11

pmol/l

0.18

243

(3020564) Creatinine [Moles/volume] in Serum or Plasma

432

0.67

0.78

29.1

20.2

102.05

87.59

umol/l

0.38

432

(3009542) Hematocrit [Volume Fraction] of Blood

450

0.67

0.76

35.8

24.8

39.26

39.32

0.02

416

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.66

0.76

1.8

1.7

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.67

0.75

1.9

1.6

—

(40768797) Stomach Pathology biopsy report

1.64

0.73

1.2

1.3

—

(40761536) Microorganisms panel - Urine sediment

1.78

0.65

5.2

3.8

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.72

0.62

1.2

1.5

—

(21494755) Public health laboratory ask at order entry panel

0.00

0.61

0.0

1.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.00

0.61

0.0

1.6

—

(3022313) Gas panel - Capillary blood

0.00

0.61

0.0

5.1

—

(3018010) Neutrophils/100 leukocytes in Blood

195

1.36

0.51

5.2

5.4

58.94

58.89

0.00

177

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

187

1.35

0.48

1.9

2.4

88.78

88.89

pmol/l

—

103

(40761511) CBC panel - Blood by Automated count

425

0.75

0.48

25.9

15.7

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

202

0.73

0.46

4.6

4.8

20.42

21.53

—

109

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.43

0.43

1.8

1.7

—

(40768804) Tissue Pathology biopsy report

168

0.72

0.42

2.4

2.3

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.56

0.42

2.6

2.2

0.25

0.21

g/l

—

(3002030) Lymphocytes/100 leukocytes in Blood

200

1.31

0.42

5.4

27.89

26.06

0.21

183

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.42

0.0

3.5

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.41

0.0

1.0

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.00

0.41

0.0

1.3

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

0.00

0.40

0.0

5.8

—

25.18

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

118

1.35

0.38

3.0

2.8

117.47

33.74

u/l

0.44

110

(40760892) CBC W Ordered Manual Differential panel - Blood

194

1.28

0.36

7.4

5.9

—

(3020630) Protein [Mass/volume] in Serum or Plasma

1.33

0.34

2.3

2.1

65.93

66.91

g/l

—

(3003694) ABO and Rh group [Type] in Blood

0.69

0.34

1.4

1.3

—

(3019069) Monocytes/100 leukocytes in Blood

196

1.27

0.33

5.5

9.64

9.00

0.47

180

(3011397) Hemoglobin [Presence] in Urine by Test strip

108

0.71

0.32

3.6

—

(3026008) Bacteria identified in Urine by Culture

141

1.28

0.30

3.5

3.4

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.33

0.29

1.9

1.7

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

199

1.24

0.29

2.1

2.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

291

0.82

0.26

4.5

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.21

0.26

6.4

2.6

1.99

2.28

g/l

—

(3022096) Basophils/100 leukocytes in Blood

192

1.22

0.25

5.3

0.59

0.01

175

(3029937) Albumin [Presence] in Urine by Test strip

116

1.26

0.24

4.3

3.8

0.00

estimate

—

(3018418) pH of Serum or Plasma

135

1.24

0.24

9.5

3.9

7.39

7.40

—

(40758558) Short blood count panel - Blood

107

1.27

0.24

7.6

7.4

—

(3002385) Erythrocyte distribution width [Ratio]

349

0.84

0.24

30.6

19.8

15.39

15.15

0.10

344

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

176

0.81

0.23

4.1

3.2

3055.61

1800.03

ng/l

0.35

139

(3044889) 12 lead EKG panel

302

1.19

0.22

4.7

4.3

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.4

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.3

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.1

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.7

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.21

0.0

2.1

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.21

0.0

2.1

—

(3008898) HLA-B27 [Presence]

0.00

0.21

0.0

1.0

—

(3006504) Eosinophils/100 leukocytes in Blood

195

1.19

0.21

5.2

5.3

2.73

2.91

0.20

178

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.21

0.0

1.2

—

(3025941) Bacteria identified in Stool by Culture

0.00

0.21

0.0

1.2

—

(1002224) Polysomnography panel

0.00

0.21

0.0

1.1

—

(3023368) Bacteria identified in Blood by Culture

148

1.20

0.19

4.4

4.3

—

(3022217) INR in Platelet poor plasma by Coagulation assay

257

1.16

0.17

21.7

15.5

1.13

1.33

inr

1.33

(3022948) Iron [Moles/volume] in Serum or Plasma

1.13

0.16

6.4

2.7

8.82

12.43

umol/l

—

(1761868) Lipid panel - Serum or Plasma

112

1.20

0.16

4.5

3.6

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

180

1.16

0.15

2.4

—

(3009261) Glucose [Presence] in Urine by Test strip

210

0.87

0.15

3.9

4.3

0.00

estimate

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

138

0.84

0.14

1.3

2.0

109.50

156.94

u/l

0.75

131

(36304419) Bacteria [Presence] in Urine

116

1.15

0.10

3.2

3.3

—

(4035726) Immunohistochemistry procedure

1.15

0.10

1.6

1.1

—

(3012516) Albumin [Mass/volume] in Urine

136

1.13

0.09

2.7

3.2

132.12

512.08

mg/l

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

164

0.89

0.09

4.7

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.03

0.08

17.9

5.6

1.10

1.05

mmol/l

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

108

1.14

0.08

2.0

2.1

—

(3019150) Specific gravity of Urine by Refractometry

0.86

0.07

3.6

4.1

—

1.02

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

223

0.91

0.07

8.3

6.4

1.22

1.20

mmol/l

0.45

183

(3013512) EKG study

142

0.89

0.07

3.1

5.0

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

172

0.91

0.06

3.1

3.4

—

(3035350) Ketones [Presence] in Urine by Test strip

210

0.93

0.04

3.8

4.3

0.00

estimate

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

249

0.94

0.03

4.3

5.6

1.91

2.52

ug/l

0.59

210

(3041096) Erythrocytes [Presence] in Urine by Automated

108

0.91

0.03

4.2

4.6

—

(3021601) Nitrite [Presence] in Urine by Test strip

208

0.94

0.02

4.6

6.1

0.00

estimate

—

(3044640) Blood type and Crossmatch panel - Blood

144

1.05

0.00

2.9

2.3

—

(3026493) Urate [Moles/volume] in Serum or Plasma

109

1.01

0.00

2.9

3.0

397.82

3885.72

umol/l

0.49

(3020682) Albumin/Creatinine [Ratio] in Urine

148

1.02

0.00

3.7

3.9

36.28

17.88

mg/mmol

—

101

(3013707) Erythrocyte sedimentation rate by Westergren method

318

1.01

0.00

3.4

4.1

16.30

14.66

mm/h

0.19

284

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.0

1.0

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.2

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.2

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.0

1.1

—

61.38

—

(4146454) Self-monitoring of blood glucose

0.00

0.0

2.8

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.0

2.0

—

(3017354) Segmented neutrophils/100 leukocytes in Blood

0.00

0.0

1.4

—

60.40

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.8

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

2.0

—

131.80

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.0

2.0

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.8

—

305.80

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

0.0

13.0

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.0

1.0

—

(3045716) Anion gap in Serum or Plasma

0.00

0.0

2.2

—

7.18

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

2.0

—

(3045788) Cell count panel - Pleural fluid

0.00

0.0

1.2

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.0

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

1.2

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

-0.00

0.0

1.3

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.0

—

4.53

—

(3003327) Ova and parasites identified in Stool by Light microscopy

0.00

-0.00

0.0

1.6

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

-0.00

0.0

1.2

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.00

-0.00

2.4

2.3

4.80

10.03

umol/l

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.3

—

(3009214) Lutropin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

7.06

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

0.85

-0.00

2.4

2.1

4.36

4.92

ug/l

—

(3000494) Fungus identified in Specimen by Culture

1.00

-0.00

1.0

1.4

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.3

—

111.57

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.1

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.1

—

Mortality – FinRegistry

↥

This endpoint is excluded (not available in FinRegistry).

Relationships between endpoints

↥

Index endpoint: GASTRIC_ULCER_ACUTE_W_HAEMORRHAGE – Gastric ulcer - Acute with haemorrhage, drug-induced

GWS hits: -

This endpoint is excluded (not available in FinRegistry).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Gastric ulcer - Acute with haemorrhage, drug-induced

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Gastric ulcer - Acute with haemorrhage, drug-induced (GASTRIC_ULCER_ACUTE_W_HAEMORRHAGE)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints