This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Pemphigus erythematosus
L12_PEMPHIGUS_ERYT
pemphigus: a rare group of blistering autoimmune diseases that affect the skin and mucous membranes.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
31 |
4. Check minimum number of eventsNone |
31 |
5. Include endpointsNone |
31 |
6. Filter based on genotype QC (FinnGen only) |
31 |
Control definitions (FinnGen only)
- Control exclude
- L12_BULLOUS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L10
- Name in latin
- Pemphigus erythematosus
Similar endpoints
↥List of similar endpoints to
Pemphigus erythematosus
based on the number of shared cases.
Similar with more cases:
- Pemphigus
- Bullous disorders
- Diseases of the skin and subcutaneous tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 361 | 221 | 139 |
| Only index persons | 275 | 181 | 94 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 58.46 | 58.70 | 57.92 |
| Only index persons | 51.41 | 51.70 | 50.84 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 31 | 19 | 12 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 46.34 | 44.35 | 49.50 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
0
30
0.00
1.04
0.0
7.8
—
—
—
0
0
10
56
2.16
1.02
1.6
1.8
—
—
—
0
0
6
30
2.23
0.93
1.7
1.9
29.50
29.53
s
—
6
30
5
91
0.46
0.84
5.0
2.8
—
—
—
0
0
0
25
0.00
0.83
0.0
4.8
—
16.68
—
0
19
7
44
1.76
0.54
1.4
1.3
—
11.62
—
0
18
8
104
0.69
0.37
2.0
4.0
—
—
—
0
0
12
95
1.43
0.33
2.3
2.1
110.98
91.51
pmol/l
—
5
54
8
63
1.36
0.31
1.8
1.6
1.21
2.91
mg/l
—
8
58
12
97
1.39
0.28
2.0
5.0
1.24
1.22
mmol/l
0.35
12
88
22
200
1.34
0.25
3.0
3.3
10.14
10.21
mm/h
0.01
22
186
26
270
0.77
0.24
15.2
16.2
67.77
75.74
umol/l
1.46
26
270
25
263
0.75
0.22
12.6
15.0
3.89
3.97
mmol/l
1.04
25
255
0
10
0.00
0.22
0.0
1.3
—
24.57
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
25
260
0.80
0.21
12.2
15.0
139.04
139.84
mmol/l
0.64
25
251
0
14
0.00
0.20
0.0
4.1
—
43.03
—
0
14
23
244
0.78
0.19
12.7
12.6
89.58
82.56
ml/min/173m2
0.66
17
201
8
67
1.26
0.19
1.5
1.8
1.76
1.21
mmol/l
—
8
58
13
112
1.28
0.18
3.0
6.4
1.23
1.22
mmol/l
0.13
13
96
6
56
1.09
0.09
2.0
1.5
—
—
—
0
0
13
127
1.04
0.00
3.8
3.7
—
—
—
0
0
12
123
0.96
0.00
2.7
2.6
84.33
87.30
ug/l
0.02
12
114
15
145
1.07
0.00
8.1
12.0
3.78
3.70
e9/l
0.08
15
128
17
173
0.96
0.00
2.4
2.8
29.53
48.44
u/l
1.44
17
166
16
162
0.97
0.00
3.4
3.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.00
—
0
6
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.00
—
0
6
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
2.97
—
0
7
0
7
0.00
0.00
0.0
6.7
—
157.81
—
0
7
0
6
0.00
0.00
0.0
1.0
—
0.00
—
0
6
0
8
0.00
0.00
0.0
1.3
—
37.50
—
0
8
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.00
—
0
6
22
215
1.08
0.00
20.9
17.2
13.87
13.80
%
0.07
22
209
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
34.07
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
12.27
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
6
65
0.90
0.00
4.2
5.9
—
19.19
—
0
31
Mortality – FinRegistry
↥Association
Association between endpoint L12_PEMPHIGUS_ERYT and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have L12_PEMPHIGUS_ERYT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: L12_PEMPHIGUS_ERYT – Pemphigus erythematosus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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