info icon

This is a non-core endpoint: only basic statistics are computed.

Defect, injury or illness of face

Z21_DEFECT_INJURY_ILLNE_FACE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 ZA8.1
  • Cause of death: ICD-10 ZA8.1

2 out of 7 registries used, show all original rules.

60

4. Check minimum number of events

None

60

5. Include endpoints

None

60

6. Filter based on genotype QC (FinnGen only)

56

Control definitions (FinnGen only)

Control exclude
Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z[AB]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 56 31 25
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 48.45 51.62 44.52

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
60
Matched controls
600
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ZA8.1
ICD-10 Finland
Fault, injury or illness in the face
+∞
86.1
60
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
11
27
4.75
3.61
11.2
8.6
6.80
6.20
mmol/l
0.15
11
27
24
124
2.56
2.95
2.9
2.9
—
—
—
0
0
5
8
6.69
2.42
7.2
2.1
8.90
8.93
kpa
—
5
8
5
8
6.69
2.42
7.2
2.1
5.26
5.13
kpa
—
5
8
22
123
2.25
2.19
6.0
2.6
—
—
—
0
0
22
123
2.25
2.19
6.1
2.6
0.22
0.15
e6/l
0.17
14
88
13
57
2.63
2.16
1.5
1.5
—
—
—
0
0
5
11
4.85
1.98
5.0
2.5
—
—
—
0
0
23
137
2.10
1.92
6.0
2.9
803.99
43.92
e6/l
0.45
14
102
16
84
2.23
1.81
5.1
3.1
66.13
166.91
ng/l
0.63
11
53
18
100
2.14
1.78
1.9
2.0
0.40
0.85
mg/l
3.20
13
76
19
109
2.09
1.73
3.8
3.6
—
—
—
0
0
34
241
1.95
1.71
3.9
3.5
0.00
0.00
estimate
—
6
43
34
243
1.92
1.65
4.5
3.6
0.00
0.00
estimate
—
6
38
25
164
1.90
1.55
3.8
3.4
23.58
44.91
ng/l
0.48
15
102
33
238
1.86
1.52
5.7
4.8
0.00
0.00
estimate
—
6
41
20
123
1.94
1.49
8.0
3.4
7.40
7.40
ph
—
6
22
24
159
1.85
1.42
7.1
3.6
67.42
61.53
e6/l
0.04
17
108
20
128
1.84
1.30
4.0
3.8
0.00
0.00
estimate
—
6
39
22
146
1.80
1.28
2.7
2.2
—
—
—
0
0
6
25
2.55
1.28
8.7
6.4
24.35
25.06
mmol/l
—
6
25
8
38
2.27
1.24
4.6
2.2
—
—
—
0
0
39
308
1.76
1.23
7.4
4.2
—
557.71
—
0
7
28
206
1.67
1.11
10.0
8.6
0.00
0.00
e9/l
0.50
21
162
12
69
1.92
1.06
3.2
2.1
12.32
12.44
umol/l
0.02
12
63
5
22
2.38
1.05
2.2
1.6
—
—
—
0
0
21
145
1.69
1.04
1.7
1.9
109.12
99.01
pmol/l
0.35
11
79
20
140
1.64
0.93
3.0
3.1
—
—
—
0
0
26
195
1.59
0.92
8.8
11.5
1.52
1.30
inr
—
6
50
30
238
1.52
0.80
7.5
6.1
9.99
10.40
umol/l
0.12
30
223
16
112
1.58
0.73
4.0
8.2
—
—
—
0
0
5
26
2.00
0.72
1.4
1.3
—
—
—
0
0
23
179
1.46
0.65
10.7
6.9
1.22
1.21
mmol/l
0.28
23
170
55
513
1.86
0.62
26.5
13.0
89.05
74.06
umol/l
0.65
55
513
55
512
1.89
0.62
16.4
10.8
—
—
—
0
0
0
21
0.00
0.61
0.0
1.1
—
—
—
0
0
14
99
1.54
0.61
5.2
3.7
3.53
9.46
mg/mmol
—
9
53
6
36
1.74
0.59
1.2
1.4
—
—
—
0
0
16
118
1.49
0.58
8.2
3.7
—
—
—
0
0
9
60
1.59
0.58
1.4
1.5
—
—
—
0
0
9
63
1.50
0.55
2.3
1.6
—
—
—
0
0
5
32
1.61
0.43
4.2
15.3
—
—
—
0
0
8
60
1.38
0.42
1.4
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
5
35
1.47
0.40
7.4
4.5
—
—
—
0
0
35
313
1.28
0.36
3.7
3.2
—
—
—
0
0
6
45
1.37
0.35
1.8
1.5
—
—
—
0
0
18
151
1.27
0.29
1.8
1.6
—
—
—
0
0
5
71
0.68
0.28
1.2
1.2
—
—
—
0
0
9
73
1.27
0.27
3.6
1.6
—
—
—
0
0
35
320
1.23
0.26
5.5
4.2
—
—
—
0
0
5
37
1.38
0.24
2.0
1.2
—
—
—
0
0
17
145
1.24
0.24
2.4
1.9
—
—
—
0
0
5
38
1.34
0.24
4.6
2.8
—
—
—
0
0
5
39
1.31
0.23
5.0
2.9
—
—
—
0
0
11
89
1.29
0.23
2.3
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
13.82
—
0
11
0
11
0.00
0.21
0.0
7.3
—
—
—
0
0
0
10
0.00
0.21
0.0
3.3
—
7.90
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
12.23
—
0
10
0
10
0.00
0.21
0.0
3.3
—
1.20
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
11.2
—
—
—
0
0
6
48
1.28
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
30
278
1.16
0.16
12.1
8.9
3.91
4.31
e9/l
0.45
24
248
9
77
1.20
0.16
3.0
1.5
—
—
—
0
0
10
118
0.82
0.16
2.9
3.0
317.60
3639.00
umol/l
—
10
108
13
113
1.19
0.14
4.1
3.9
—
—
—
0
0
12
105
1.18
0.12
2.7
1.7
—
—
—
0
0
20
185
1.12
0.10
1.7
2.6
—
—
—
0
0
18
195
0.89
0.10
1.9
1.9
—
—
—
0
0
14
131
1.09
0.04
1.2
1.3
0.81
1.88
u/ml
—
7
37
22
214
1.04
0.00
12.4
5.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
54
0.92
-0.00
1.6
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
48.16
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
21.5
—
2368.17
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
0.39
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
215.60
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
34.92
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
1.20
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
421.40
—
0
5
0
7
0.00
-0.00
0.0
2.7
—
104.86
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
338.40
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
16.7
—
1103.50
—
0
6
0
7
0.00
-0.00
0.0
2.7
—
3.96
—
0
7
5
53
0.94
-0.00
1.6
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_DEFECT_INJURY_ILLNE_FACE – Defect, injury or illness of face

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).