Miliary tuberculosis

AB1_TUBERCU_MILIARY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A19
  • Hospital discharge: ICD-9 01[8]
  • Hospital discharge: ICD-8 01[8]
  • Cause of death: ICD-10 A19
  • Cause of death: ICD-9 01[8]
  • Cause of death: ICD-8 01[8]

2 out of 7 registries used, show all original rules.

64

4. Check minimum number of events

None

64

5. Include endpoints

None

64

6. Filter based on genotype QC (FinnGen only)

61

Control definitions (FinnGen only)

Control exclude
AB1_TUBERCULOSIS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 61 22 39
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 70.01 68.48 70.87

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
64
Matched controls
640
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A19.9
ICD-10 Finland
Miliary tuberculosis, unspecified
+∞
21.0
19
*
A19.1
ICD-10 Finland
Acute miliary tuberculosis of multiple sites
+∞
21.0
19
*
A19.0
ICD-10 Finland
Acute miliary tuberculosis of a single specified site
+∞
12.9
12
*
R50.9
ICD-10 Finland
Fever, unspecified
5.6
9.6
25
66
A19.8
ICD-10 Finland
Other miliary tuberculosis
+∞
9.6
9
*
A19.2
ICD-10 Finland
Acute miliary tuberculosis, unspecified
+∞
9.6
9
*
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
9.6
9
*
JN3AD
NOMESCO Finland
Abdominal CT examination
5.4
7.3
17
40
L04AX01
ATC
azathioprine; systemic
19.4
7.0
10
6
H02AB07
ATC
prednisone; oral
4.3
6.4
21
65
M05BA04
ATC
alendronic acid; oral
6.2
6.3
17
35

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
23
46
7.24
12.08
1.2
1.8
—
—
—
0
0
16
44
4.52
5.62
1.0
1.5
—
—
—
0
0
21
73
3.79
5.39
6.3
6.6
0.96
1.10
mmol/l
1.67
21
64
21
75
3.68
5.16
2.6
2.4
0.83
0.83
mmol/l
0.03
21
66
34
169
3.16
4.87
6.1
4.1
—
—
—
0
0
11
22
5.80
4.23
1.7
1.0
—
—
—
0
0
36
202
2.79
3.91
19.3
6.4
—
—
—
0
0
14
47
3.53
3.68
1.4
1.2
—
—
—
0
0
12
32
4.37
3.62
1.4
1.2
—
—
—
0
0
18
73
3.04
3.51
1.7
1.5
4.19
3.74
g/l
—
10
45
13
39
3.92
3.48
1.5
1.4
—
—
—
0
0
10
24
4.74
3.36
6.8
3.7
—
—
—
0
0
34
197
2.55
3.32
16.7
5.9
0.61
0.55
%
0.32
34
173
8
15
5.92
3.31
1.9
1.0
—
—
—
0
0
34
200
2.49
3.18
16.6
6.0
2.69
2.53
%
0.18
34
177
34
201
2.48
3.13
16.9
6.3
9.19
9.03
%
0.11
34
180
34
204
2.42
3.00
16.8
6.0
22.19
24.30
%
0.59
34
182
6
10
6.48
2.76
2.3
4.7
—
—
—
0
0
33
201
2.32
2.75
15.2
5.6
63.08
59.74
%
0.88
33
178
9
25
4.01
2.69
5.4
2.8
—
—
—
0
0
14
57
2.86
2.67
2.5
3.4
68.66
68.15
e9/l
—
9
47
38
255
2.21
2.41
8.8
6.3
1.22
1.21
mmol/l
0.26
31
206
16
74
2.55
2.39
2.1
2.0
—
—
—
0
0
26
154
2.16
2.22
5.8
4.3
7.42
7.40
ph
—
5
31
7
19
4.00
2.22
1.7
1.3
—
—
—
0
0
11
43
2.88
2.21
7.0
4.0
—
—
—
0
0
38
267
2.04
2.01
11.1
5.3
9.19
12.09
umol/l
2.28
38
251
11
47
2.62
1.90
10.6
7.9
—
—
—
0
0
19
105
2.15
1.89
8.3
4.4
—
—
—
0
0
6
19
3.37
1.70
1.3
1.1
—
—
—
0
0
11
50
2.45
1.68
3.3
1.4
—
—
—
0
0
10
44
2.50
1.65
1.6
1.4
—
—
—
0
0
5
14
3.78
1.64
1.0
1.8
—
—
—
0
0
5
14
3.78
1.64
2.2
2.1
—
—
—
0
0
43
330
1.92
1.62
9.0
5.1
—
—
—
0
0
27
179
1.88
1.60
6.9
3.3
—
—
—
0
0
7
28
2.68
1.50
11.1
7.0
—
—
—
0
0
10
47
2.34
1.42
6.0
3.3
—
—
—
0
0
35
263
1.73
1.31
16.8
18.3
1.25
1.44
inr
0.61
13
78
11
57
2.12
1.26
8.3
5.6
95.36
94.69
%
0.21
11
57
20
133
1.73
1.12
10.9
3.3
—
—
—
0
0
5
21
2.49
1.11
1.8
1.2
—
—
—
0
0
23
163
1.64
1.02
2.7
2.1
—
—
—
0
0
24
172
1.63
1.02
2.2
2.3
—
—
—
0
0
27
201
1.59
0.98
2.6
2.1
87.51
84.82
pmol/l
0.09
18
90
17
113
1.69
0.94
8.5
6.4
—
—
—
0
0
6
29
2.18
0.92
2.2
2.8
—
—
—
0
0
12
75
1.74
0.82
8.0
5.4
103.83
104.37
mmol/l
0.11
12
75
0
24
0.00
0.81
0.0
6.5
—
—
—
0
0
30
237
1.50
0.80
7.9
4.7
0.00
0.00
estimate
—
6
50
30
237
1.50
0.80
10.3
6.3
0.00
0.00
estimate
—
6
46
7
38
1.94
0.76
9.9
6.2
94.40
93.04
%
—
7
38
9
57
1.67
0.75
1.6
1.8
—
—
—
0
0
7
40
1.84
0.74
9.9
6.0
0.51
0.68
%
—
7
40
8
126
0.58
0.73
1.9
4.1
—
—
—
0
0
7
41
1.79
0.72
9.9
5.2
1.03
1.47
%
—
7
41
30
241
1.46
0.72
8.0
4.7
0.00
0.00
estimate
—
7
46
0
20
0.00
0.61
0.0
1.2
—
44.70
—
0
7
8
53
1.58
0.61
10.1
5.8
93.62
118.92
g/l
—
8
53
7
46
1.58
0.50
1.6
1.4
—
—
—
0
0
8
55
1.52
0.45
1.5
3.3
2.40
6.23
ug/l
—
8
46
5
32
1.61
0.43
7.0
2.3
—
—
—
0
0
37
411
0.76
0.42
4.4
4.8
1.46
1.40
mmol/l
0.30
32
358
0
17
0.00
0.41
0.0
1.5
—
—
—
0
0
0
17
0.00
0.41
0.0
3.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
18
146
1.32
0.38
8.6
4.8
0.00
0.00
estimate
—
5
45
6
43
1.44
0.36
3.5
3.7
—
—
—
0
0
6
43
1.44
0.36
7.7
4.0
—
—
—
0
0
42
454
0.78
0.34
48.5
21.6
4.02
4.04
mmol/l
0.12
42
433
35
314
1.25
0.33
3.2
3.9
15.30
15.16
pmol/l
0.12
28
267
42
453
0.79
0.33
48.0
21.6
138.90
139.59
mmol/l
0.72
42
432
38
413
0.80
0.31
4.5
4.8
4.27
4.31
mmol/l
0.08
32
364
39
422
0.81
0.30
4.7
5.4
2.29
2.47
mmol/l
0.55
33
370
42
448
0.82
0.25
32.2
17.9
—
—
—
0
0
0
10
0.00
0.21
0.0
3.0
—
19.25
—
0
10
6
50
1.22
0.20
1.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
3.2
—
106.64
—
0
14
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
3.2
—
—
—
0
0
0
14
0.00
0.20
0.0
3.2
—
4.09
—
0
14
30
322
0.87
0.16
50.9
25.7
326.93
330.38
g/l
0.97
30
317
38
397
0.89
0.11
3.8
4.3
1.35
1.24
mmol/l
0.47
32
343
5
45
1.12
0.10
2.8
3.1
191.80
230.14
ng/l
—
5
39
43
445
0.90
0.09
45.8
21.6
95.33
90.09
umol/l
0.28
43
445
17
156
1.12
0.09
4.5
5.1
—
—
—
0
0
7
64
1.11
0.08
1.4
1.3
—
—
—
0
0
13
142
0.89
0.07
6.0
4.4
—
—
—
0
0
29
301
0.93
0.05
5.9
4.3
—
—
—
0
0
11
102
1.09
0.03
1.9
2.7
2.50
2.47
mmol/l
0.37
11
88
10
108
0.91
0.03
1.3
1.3
—
—
—
0
0
38
384
0.97
0.00
4.1
4.8
2.01
2.10
mu/l
0.15
33
326
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.2
—
4.47
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
5.76
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
52.46
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
41
410
1.00
-0.00
5.0
5.4
6.04
6.18
mmol/l
0.26
36
354
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_TUBERCU_MILIARY – Miliary tuberculosis

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).