Fat embolism (traumatic)

ST19_FAT_EMBOL_TRAUMAT

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — T79.1 Cause of death: ICD-10 — T79.1 2 out of 7 registries used, show all original rules.	69
4. Check minimum number of events None	69
5. Include endpoints None	69
6. Filter based on genotype QC (FinnGen only)	67

Control definitions (FinnGen only)

Control exclude: ST19_ALIQU_COMPLICATI_PRAECO_TRAUMAT

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: T79
Name in latin: Embolia adiposa traumatica

NAME	ST19_FAT_EMBOL_TRAUMAT
CONTROL_EXCLUDE	ST19_ALIQU_COMPLICATI_PRAECO_TRAUMAT
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	T791
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	T791
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Fat embolism (traumatic) based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	67	30	37
Unadjusted period prevalence (%)	0.01	0.01	0.02
Median age at first event (years)	80.59	82.08	79.37

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
69: Matched controls
690

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

T79.1

ICD-10 Finland

Fat embolism (traumatic)

+∞

99.1

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

10.4

16.9

202

S72.0

ICD-10 Finland

Fracture of neck of femur

8.4

14.7

NFB20

NOMESCO Finland

Primary partial prosthetic replacement of hip joint using cement, other or unspecified

8.4

7.0

I25.1

ICD-10 Finland

Atherosclerotic heart disease

3.7

6.7

172

S72.1

ICD-10 Finland

Pertrochanteric fracture

6.8

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

184

2.38

3.05

2.2

2.3

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

7.17

2.93

1.3

2.3

—

(3022313) Gas panel - Capillary blood

4.34

2.89

8.4

5.7

—

(3044640) Blood type and Crossmatch panel - Blood

142

2.33

2.73

2.1

—

(3003694) ABO and Rh group [Type] in Blood

2.57

1.1

1.4

—

(3019060) Gas panel - Arterial blood

2.92

2.27

6.2

3.2

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

3.77

2.11

9.9

6.4

26.16

24.78

mmol/l

—

(3009343) pH of Capillary blood

2.90

2.11

7.9

4.4

—

7.41

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

4.80

1.97

1.2

1.5

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

2.66

1.96

5.4

7.6

115.55

120.78

g/l

0.35

(3042936) Bacteria identified in Isolate by Culture

2.23

1.61

2.6

1.7

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

103

2.01

1.60

2.3

1.9

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

3.51

1.55

1.8

1.9

0.57

0.33

ug/l

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.66

1.49

6.9

7.5

92.76

93.31

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

3.09

1.38

3.6

3.5

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.19

1.36

3.2

1.6

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

223

1.71

1.32

7.8

5.9

1.18

1.22

mmol/l

0.99

201

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

203

0.51

1.32

2.1

2.6

—

(3023520) Reticulocytes [#/volume] in Blood

2.31

1.26

2.4

2.7

82.83

65.96

e9/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.85

1.20

2.0

1.7

—

(3020891) Body temperature

2.61

1.17

10.2

3.6

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.61

1.17

2.0

2.1

—

(3019225) pH of Specimen

2.07

1.13

1.6

3.3

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.05

1.00

7.3

2.0

—

(3023368) Bacteria identified in Blood by Culture

163

1.62

1.00

4.1

4.0

—

(3026008) Bacteria identified in Urine by Culture

174

1.58

0.94

4.4

4.2

—

(3000991) Gas panel - Venous blood

2.02

0.92

1.9

8.0

—

(3037467) Urinalysis macro (dipstick) panel - Urine

299

1.51

0.89

5.2

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.82

0.88

6.8

6.6

102.55

104.09

mmol/l

0.71

(3024561) Albumin [Mass/volume] in Serum or Plasma

204

1.53

0.88

5.0

4.1

32.03

33.87

g/l

0.84

191

(36660697) Celiac disease serology panel - Serum

2.17

0.76

1.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.68

0.70

1.8

1.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

194

1.45

0.70

4.6

6.2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.63

0.63

2.0

1.6

—

(3009542) Hematocrit [Volume Fraction] of Blood

446

1.44

0.62

32.1

26.2

38.13

37.94

0.07

416

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

144

1.44

0.59

2.3

1.8

278.05

391.90

u/l

0.30

137

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.73

0.58

4.5

6.8

20.33

24.13

mmol/l

—

(1761868) Lipid panel - Serum or Plasma

108

0.61

0.54

1.6

3.1

—

(3002256) Pathology report gross observation

1.55

0.53

1.0

1.5

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.53

0.52

5.1

2.5

0.81

0.80

mmol/l

0.05

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

0.58

0.49

1.6

1.8

1.41

1.19

mmol/l

—

(3015736) pH of Urine

169

0.72

0.43

5.0

4.5

—

5.59

—

(3022621) pH of Urine by Test strip

1.61

0.43

3.4

4.2

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

417

1.31

0.42

26.1

18.8

19.90

25.13

mg/l

0.73

355

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.55

0.42

1.8

1.6

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

0.00

0.41

0.0

1.4

—

100.62

—

(3029937) Albumin [Presence] in Urine by Test strip

116

1.37

0.41

5.3

5.4

0.00

estimate

—

(3022145) Colonoscopy Study observation

1.46

0.40

1.2

1.4

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

358

1.28

0.40

20.9

18.6

65.33

69.72

ml/min/173m2

0.52

302

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

348

1.28

0.40

3.2

3.9

1.29

1.23

mmol/l

0.20

312

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.39

0.0

4.3

—

23.38

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

424

1.25

0.33

28.4

21.4

94.11

86.75

umol/l

0.57

424

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

334

1.23

0.32

6.1

6.9

77.47

80.08

u/l

0.23

314

(40758558) Short blood count panel - Blood

115

0.75

0.30

9.2

6.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

198

1.24

0.30

2.5

2.2

66.04

89.48

pmol/l

1.65

101

(3044889) 12 lead EKG panel

284

0.81

0.30

5.9

4.1

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

361

1.18

0.23

3.7

4.4

4.24

4.29

mmol/l

0.08

330

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

4.4

—

89.60

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

3.4

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

234

1.18

0.21

3.9

5.3

15.44

12.65

umol/l

0.35

219

(3024928) Oxygen saturation in Venous blood

0.00

0.21

0.0

3.1

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

0.24

—

(3021601) Nitrite [Presence] in Urine by Test strip

205

1.18

0.20

5.3

7.0

0.00

estimate

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.00

0.20

0.0

1.3

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.20

0.0

2.1

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.20

0.0

1.4

—

1.18

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.19

0.20

4.8

4.5

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

237

1.16

0.17

9.7

6.6

1.18

1.22

mmol/l

1.12

200

(3015377) Calcium [Moles/volume] in Serum or Plasma

169

1.17

0.17

2.1

3.5

2.37

2.35

mmol/l

0.28

148

(3009261) Glucose [Presence] in Urine by Test strip

208

1.16

0.17

4.5

5.1

0.00

estimate

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

358

1.14

0.15

3.7

4.4

1.30

1.39

mmol/l

0.89

322

(3022217) INR in Platelet poor plasma by Coagulation assay

250

1.13

0.14

42.5

20.7

1.85

1.41

inr

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

167

0.87

0.12

6.1

5.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

123

0.87

0.09

4.0

4.7

—

(36304419) Bacteria [Presence] in Urine

130

0.91

0.05

3.0

3.4

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

379

1.07

0.05

4.1

4.8

2.55

2.47

mmol/l

0.20

341

(40768804) Tissue Pathology biopsy report

150

1.09

0.05

1.7

2.2

—

(3013512) EKG study

142

1.07

0.03

6.3

4.6

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

374

1.04

0.00

6.2

6.0

42.83

41.48

mmol/mol

0.33

349

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

177

1.02

0.00

2.0

2.3

81.23

75.19

nmol/l

0.34

154

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

175

1.04

0.00

4.7

3.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.05

0.00

5.6

4.7

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

119

1.01

0.00

2.5

4.8

21.76

22.37

—

(3035350) Ketones [Presence] in Urine by Test strip

208

1.01

0.00

4.5

5.0

0.00

estimate

—

(40761511) CBC panel - Blood by Automated count

412

0.99

0.00

27.0

17.6

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

3.4

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.1

—

(3016038) Potassium [Moles/volume] in Urine

0.00

0.0

1.0

—

39.50

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

1.3

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.4

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.0

1.6

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.4

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.1

—

(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.02

-0.00

1.4

—

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.2

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

3.2

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.2

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

3.0

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.2

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

4.3

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

3.4

—

32.20

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.4

—

(3006270) Folate [Moles/volume] in Blood

0.00

-0.00

0.0

1.2

—

385.17

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.9

—

10.69

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

21.00

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.5

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

16.68

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

-0.00

0.0

1.4

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

10.00

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

742.24

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.2

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

2.0

—

49.40

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

-0.00

0.0

5.6

—

33.96

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

-0.00

0.0

1.1

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

4.3

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

-0.00

0.0

3.8

—

64.40

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

2.7

—

88.07

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_FAT_EMBOL_TRAUMAT – Fat embolism (traumatic)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Fat embolism (traumatic)

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Fat embolism (traumatic) (ST19_FAT_EMBOL_TRAUMAT)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints