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This is a non-core endpoint: only basic statistics are computed.

Merkel cell carcinoma of skin

C3_MERKEL_CELL_SKIN

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C44
  • Cancer registry: Morphology ICD-O-3 8247
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

43

4. Check minimum number of events

None

43

5. Include endpoints

None

43

6. Filter based on genotype QC (FinnGen only)

42

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 42 23 19
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 74.18 74.46 73.83

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
18
10
29.65
13.53
1.8
1.3
—
—
—
0
0
29
92
7.61
9.85
4.9
1.6
—
—
—
0
0
14
19
10.34
7.13
1.7
1.0
—
—
—
0
0
21
96
3.32
3.59
2.5
2.0
—
—
—
0
0
8
20
4.66
2.72
1.1
1.1
—
—
—
0
0
28
171
2.83
2.64
6.1
5.2
3.28
4.52
e9/l
4.32
23
141
28
171
2.83
2.64
6.5
5.1
1.23
1.22
mmol/l
0.34
23
157
19
105
2.45
2.07
4.2
3.1
7.41
7.40
ph
—
5
12
6
19
3.49
1.73
1.0
1.3
—
—
—
0
0
14
74
2.32
1.62
1.1
1.3
—
—
—
0
0
10
48
2.41
1.41
1.7
1.9
—
—
—
0
0
17
106
2.00
1.28
2.5
2.9
—
—
—
0
0
25
179
1.95
1.26
29.3
16.3
1.14
1.32
inr
—
7
47
16
98
2.01
1.26
3.0
4.3
—
—
—
0
0
6
26
2.51
1.23
7.3
9.3
—
—
—
0
0
22
152
1.92
1.23
8.9
7.6
0.00
0.00
e9/l
0.50
16
122
20
135
1.90
1.19
3.4
4.3
203.65
63.69
e6/l
0.49
15
89
20
136
1.88
1.15
3.9
5.0
—
—
—
0
0
13
77
1.99
1.11
5.2
4.9
—
—
—
0
0
9
49
2.05
1.07
2.0
2.1
—
—
—
0
0
6
29
2.24
0.93
3.7
2.1
5.00
4.96
umol/l
—
6
24
33
274
1.88
0.91
20.3
18.8
16.49
15.10
%
0.43
33
269
8
45
1.95
0.90
4.5
5.8
105.25
104.73
mmol/l
—
8
45
37
323
2.04
0.87
21.6
15.5
26.84
25.85
mg/l
0.07
32
256
5
25
2.13
0.75
4.8
3.1
—
—
—
0
0
7
42
1.79
0.72
1.4
1.6
—
—
—
0
0
5
27
1.96
0.71
2.6
3.4
—
—
—
0
0
14
97
1.66
0.70
5.5
3.7
0.00
0.00
estimate
—
6
31
5
30
1.75
0.63
1.6
1.3
—
—
—
0
0
30
255
1.58
0.62
5.4
4.1
—
—
—
0
0
37
331
1.84
0.61
23.2
14.3
—
—
—
0
0
22
176
1.51
0.59
5.4
3.7
0.00
0.00
estimate
—
6
34
9
61
1.60
0.59
2.1
2.4
2.22
2.18
g/l
—
9
55
5
31
1.69
0.45
4.6
2.7
—
—
—
0
0
13
100
1.43
0.39
3.8
2.0
3.78
2.83
mg/l
0.63
13
83
37
345
1.52
0.37
29.4
17.5
85.76
83.50
umol/l
0.14
37
345
6
43
1.46
0.37
4.5
3.8
0.92
1.51
mmol/l
—
6
36
6
44
1.42
0.36
4.5
3.8
—
—
—
0
0
27
238
1.36
0.36
5.9
4.8
—
7920.71
—
0
7
21
179
1.34
0.34
4.8
3.8
0.00
0.00
estimate
—
6
26
7
51
1.44
0.34
1.1
1.2
—
—
—
0
0
5
37
1.40
0.24
5.4
5.8
120.00
123.49
g/l
—
5
37
13
108
1.29
0.23
5.2
3.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
139.40
—
0
5
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
20
179
1.22
0.19
7.0
5.2
0.00
0.00
estimate
—
5
31
26
239
1.22
0.19
4.4
4.2
—
—
—
0
0
25
270
0.82
0.18
35.5
20.7
328.08
330.80
g/l
0.83
25
265
19
170
1.21
0.18
2.6
2.1
96.57
88.00
pmol/l
0.36
12
83
6
54
1.13
0.09
1.0
1.9
0.83
0.80
mmol/l
—
6
47
10
89
1.16
0.07
4.5
4.0
—
—
—
0
0
9
99
0.89
0.07
3.8
3.7
—
—
—
0
0
10
91
1.13
0.05
5.3
3.2
—
—
—
0
0
13
133
0.97
0.00
4.1
3.4
—
—
—
0
0
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.1
—
1.06
—
0
8
9
94
0.95
-0.00
2.1
1.9
726.78
429.14
pmol/l
—
9
83
0
5
0.00
-0.00
0.0
1.0
—
25.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.5
—
106.67
—
0
6
0
6
0.00
-0.00
0.0
4.5
—
9.00
—
0
6
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
108.78
—
0
9
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
2.62
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
4.40
—
0
5
0
6
0.00
-0.00
0.0
2.2
—
5.27
—
0
6
0
6
0.00
-0.00
0.0
2.2
—
7.30
—
0
6
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
0.28
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
53.17
—
0
6
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
8
82
0.97
-0.00
8.5
4.3
—
1.02
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
619.30
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.31
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
4.04
—
0
9
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_MERKEL_CELL_SKIN – Merkel cell carcinoma of skin

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).