Malignant neoplasm of placenta, excluding all cancers (controls excluding all cancers)

C3_PLACENTA_EXALLC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule only females	293373
2. Check conditions None	293373
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — C58 Hospital discharge: ICD-9 — 181 Hospital discharge: ICD-8 — 181 Cause of death: ICD-10 — C58 Cause of death: ICD-9 — 181 Cause of death: ICD-8 — 181 Cancer registry: Topography ICD-O-3 — C58 Cancer registry: Morphology ICD-O-3 — ANY Cancer registry: Behaviour codes — 3 3 out of 7 registries used, show all original rules.	47
4. Check minimum number of events None	47
5. Include endpoints None	47
6. Filter based on genotype QC (FinnGen only)	47

Control definitions (FinnGen only)

Control exclude: C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze: DF12

NAME	C3_PLACENTA_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE_EXALLC
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	C58
HD_ICD_9	181
HD_ICD_8	181
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	C58
COD_ICD_9	181
COD_ICD_8	181
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO	C58
CANC_TOPO_EXCL
CANC_MORPH	ANY
CANC_MORPH_EXCL
CANC_BEHAV	3

Similar endpoints

↥

List of similar endpoints to Malignant neoplasm of placenta, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Malignant neoplasm of placenta

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	47	47	-
Unadjusted period prevalence (%)	0.02	0.02	-
Median age at first event (years)	31.89	31.89	-

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

8.71

9.66

20.0

2.4

3027.1

17137.9

u/l

—

(4035726)

11.46

4.16

1.0

1.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

3.12

3.25

2.1

1.9

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

3.47

2.80

9.6

9.2

—

(3044640) Blood type and Crossmatch panel - Blood

107

2.51

2.33

2.4

1.9

—

(40761535) Cells panel - Urine sediment

3.39

1.88

5.4

3.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.90

1.75

1.3

1.4

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.80

1.69

1.4

1.3

—

(3023368) Bacteria identified in Blood by Culture

2.38

1.68

2.5

3.4

—

(3022145) Colonoscopy Study observation

2.71

1.62

1.4

1.3

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

3.60

1.56

2.4

1.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

196

1.89

1.26

4.5

4.8

0.0

estimate

—

(3009261) Glucose [Presence] in Urine by Test strip

197

1.87

1.24

3.6

3.5

0.0

estimate

—

(3019060) Gas panel - Arterial blood

2.67

1.18

7.4

3.8

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

2.67

1.18

9.0

5.6

27.0

25.3

mmol/l

—

(3029937) Albumin [Presence] in Urine by Test strip

100

1.91

1.16

4.4

3.8

0.0

estimate

—

(3002256) Pathology report gross observation

2.39

1.14

1.0

1.1

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

172

1.81

1.14

3.9

4.0

—

(40758558) Short blood count panel - Blood

1.90

1.11

8.9

4.9

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

128

0.47

1.09

1.3

1.6

1.2

1.4

mmol/l

—

108

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.03

1.06

1.6

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

156

1.77

1.06

3.8

3.3

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

189

1.69

0.93

4.5

3.7

8.2

9.9

umol/l

0.85

173

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.79

0.91

4.1

3.7

—

(3000492) Spirometry study

2.00

0.85

1.2

1.4

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

275

1.67

0.79

8.1

5.4

75.5

76.2

u/l

0.05

252

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.71

0.76

1.5

1.8

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

149

1.60

0.75

6.1

4.4

1.2

mmol/l

0.06

138

(3002173) Hemoglobin [Mass/volume] in Arterial blood

2.12

0.75

7.4

3.6

120.8

117.8

g/l

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.03

0.73

1.6

1.0

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.95

0.70

1.2

1.5

—

(3025941) Bacteria identified in Stool by Culture

1.95

0.70

1.0

1.1

—

(3035350) Ketones [Presence] in Urine by Test strip

199

1.55

0.70

3.8

3.4

0.0

estimate

—

(3027008) Opiates [Presence] in Urine

0.00

0.62

0.0

1.1

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.62

0.0

1.1

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.62

0.0

1.1

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.62

0.0

1.1

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.58

0.61

1.3

1.5

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.66

0.57

2.2

1.7

—

(3044889) 12 lead EKG panel

256

1.48

0.55

2.2

3.3

—

(40761511) CBC panel - Blood by Automated count

430

0.64

0.54

13.3

9.4

—

(36304419) Bacteria [Presence] in Urine

1.55

0.53

2.4

3.0

—

(3018095) Leukocytes [#/volume] in Urine

122

1.47

0.51

2.8

3.5

17.6

70.2

e6/l

0.83

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.50

0.48

2.0

2.3

—

(3037467) Urinalysis macro (dipstick) panel - Urine

292

1.44

0.46

4.5

4.2

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

1.68

0.44

7.4

3.5

5.5

5.4

kpa

—

(3027801) Oxygen [Partial pressure] in Arterial blood

1.68

0.44

7.4

3.5

11.5

11.8

kpa

—

(42870588) Differential panel, method unspecified - Blood

126

1.41

0.43

9.4

5.4

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.42

0.0

1.3

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.42

0.0

1.1

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

0.42

0.0

2.0

—

23.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

108

1.42

0.41

3.4

3.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.43

0.41

1.5

2.0

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

305

0.73

0.41

4.4

3.6

—

(3016879) Cocaine [Presence] in Urine

0.00

0.41

0.0

1.1

—

(3026008) Bacteria identified in Urine by Culture

137

1.38

0.39

3.2

3.1

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.61

0.39

1.0

2.2

—

(3022217) INR in Platelet poor plasma by Coagulation assay

1.43

0.39

4.8

6.4

—

1.1

—

(3042936) Bacteria identified in Isolate by Culture

1.42

0.36

1.8

1.5

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

121

1.35

0.34

2.2

3.5

22.5

25.2

ng/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

113

1.34

0.31

2.4

2.8

—

(3031040) Bacteria [#/volume] in Urine by Automated count

272

1.28

0.28

4.7

4.6

—

59.4

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

326

0.78

0.27

3.9

4.2

14.9

14.5

pmol/l

0.35

301

(40768804) Tissue Pathology biopsy report

136

1.27

0.24

1.8

1.7

—

(36660697) Celiac disease serology panel - Serum

1.35

0.24

1.4

1.2

—

(3021960) Folate [Moles/volume] in Serum or Plasma

1.31

0.23

1.9

1.3

21.6

nmol/l

0.00

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

2.8

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

7.5

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

10.1

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.1

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

3.5

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

0.0

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.21

0.0

1.1

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

0.0

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.21

0.0

3.3

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

1.0

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

38.6

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

0.0

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.9

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.29

0.21

3.3

3.1

4.2

3.3

e6/l

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

2.4

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

0.00

0.21

0.0

2.4

—

25.0

—

(1761868) Lipid panel - Serum or Plasma

152

0.80

0.21

2.3

2.7

—

(3048689) Calprotectin [Mass/mass] in Stool

1.15

0.18

2.9

1.8

61.9

64.0

ug/g

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

111

1.24

0.18

1.3

1.7

—

(3000850) Epithelial cells [#/volume] in Urine

1.23

0.18

1.5

2.4

8.0

6.4

e6/l

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.17

0.17

1.4

1.7

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.12

0.10

1.6

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

156

1.14

0.10

2.1

1.7

92.1

93.6

pmol/l

—

(3015736) pH of Urine

166

1.14

0.09

4.0

3.3

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

276

1.13

0.09

2.7

2.9

69.4

39.5

u/l

0.57

258

(3026782) Osmolality of Urine

1.08

0.09

1.5

2.3

555.5

574.5

mosm/kgh2o

—

(3009542) Hematocrit [Volume Fraction] of Blood

386

0.92

0.07

15.8

11.4

38.9

40.1

0.85

295

(3013707) Erythrocyte sedimentation rate by Westergren method

300

1.10

0.05

5.2

4.0

11.4

11.1

mm/h

0.08

274

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

121

1.10

0.04

1.2

1.3

—

(3003694) ABO and Rh group [Type] in Blood

102

1.10

0.03

1.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.08

0.01

2.7

5.1

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

158

1.02

0.00

2.9

2.1

80.9

80.0

nmol/l

0.05

137

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.1

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

2.0

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(4306422)

0.00

0.0

1.1

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

1.6

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.0

1.7

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

2.4

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

1.3

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.4

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

0.0

1.4

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

0.0

1.4

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

1.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

1.8

—

107.8

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

2.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

1.8

—

4.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.4

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.0

1.7

—

7.3

—

(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.0

1.5

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(4268621)

0.00

0.0

1.6

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.0

—

(3013512) EKG study

0.97

0.00

2.8

3.5

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

1.8

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.4

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.0

1.6

—

1.5

—

(3025149) Bordetella pertussis IgA Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.8

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.0

1.2

—

91.0

—

(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.4

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_PLACENTA_EXALLC – Malignant neoplasm of placenta, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Malignant neoplasm of placenta, excluding all cancers (controls excluding all cancers)

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Malignant neoplasm of placenta, excluding all cancers (controls excluding all cancers) (C3_PLACENTA_EXALLC)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Relationships between endpoints