Drug-induced Cushing's syndrome

DRUGADVERS_CUSHI_SYNDR

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — E24.2# 1 out of 7 registries used, show all original rules.	41
4. Check minimum number of events None	41
5. Include endpoints None	41
6. Filter based on genotype QC (FinnGen only)	41

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: C
First used in FinnGen datafreeze: DF5

NAME	DRUGADVERS_CUSHI_SYNDR
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E242
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Drug-induced Cushing's syndrome based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	190	121	67
Only index persons	173	112	61
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	53.48	54.37	51.77
Only index persons	53.34	54.13	51.89

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	41	29	12
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	53.04	49.15	62.45

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3018418) pH of Serum or Plasma

11.51

12.76

5.9

3.3

7.4

—

(42870588) Differential panel, method unspecified - Blood

12.21

11.76

12.5

5.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

11.99

11.33

2.2

1.8

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

124

13.37

11.26

10.3

4.9

1.2

mmol/l

0.14

116

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

139

13.96

10.84

10.5

5.7

1.2

mmol/l

0.04

120

(3000991) Gas panel - Venous blood

10.73

9.88

8.9

2.8

—

(3004588) Protein electrophoresis panel - Serum or Plasma

11.70

9.87

2.8

1.4

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

8.13

9.67

2.5

18.6

23.9

0.75

(3014111) Lactate [Moles/volume] in Serum or Plasma

10.19

8.92

10.8

2.2

1.8

1.1

mmol/l

1.55

(3006315) Basophils [#/volume] in Blood

150

10.06

8.89

12.5

5.7

0.0

e9/l

0.64

133

(3001604) Monocytes [#/volume] in Blood

151

9.96

8.82

12.5

5.6

0.7

0.6

e9/l

1.88

133

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

11.70

8.44

1.0

1.1

0.3

g/l

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

10.70

7.93

1.0

1.1

1.4

1.3

g/l

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

10.70

7.93

9.2

4.4

0.8

0.7

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

9.03

7.56

2.2

2.1

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

9.85

7.46

3.5

3.2

21.8

24.6

mmol/l

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

9.85

7.46

8.9

4.2

1.0

2.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

113

6.35

7.42

5.5

2.7

—

(3037522) Nuclear Ab [Titer] in Serum

6.19

7.38

1.9

1.3

400.0

587.7

titre

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

140

6.83

7.08

4.6

2.1

73.6

74.4

nmol/l

0.06

130

(3014576) Chloride [Moles/volume] in Serum or Plasma

6.81

7.05

9.0

4.3

105.6

103.7

mmol/l

0.67

(3014007) Fractional oxyhemoglobin in Arterial blood

9.12

7.03

9.2

4.4

94.6

91.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

6.38

6.91

2.6

1.5

—

(3005322) IgE [Units/volume] in Serum or Plasma

7.99

6.82

2.1

1.1

575.1

105.1

u/ml

0.54

(3021589) Normoblasts [#/volume] in Blood

135

6.31

6.78

19.8

7.8

0.0

e9/l

0.49

109

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

113

5.66

6.67

2.3

1.9

86.9

96.4

pmol/l

0.52

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

5.99

6.47

2.6

1.5

—

(3023368) Bacteria identified in Blood by Culture

5.19

6.35

10.1

4.2

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

6.79

5.89

3.6

2.5

5.4

5.6

kpa

0.25

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

5.10

5.79

3.0

1.8

—

(3012544) pH of Venous blood

6.47

5.62

3.6

2.6

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

12.38

5.33

2.4

1.0

0.0

g/l

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

12.38

5.33

2.4

1.0

0.1

1.2

g/l

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

12.38

5.33

2.4

1.0

0.0

g/l

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

12.38

5.33

2.4

1.0

0.0

g/l

—

(36304419) Bacteria [Presence] in Urine

4.48

5.32

5.8

2.5

—

(3030467) Casts [#/volume] in Urine by Automated count

4.42

5.22

5.8

2.5

0.4

0.6

e6/l

0.30

(3035350) Ketones [Presence] in Urine by Test strip

149

4.78

5.02

4.6

3.1

0.0

estimate

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

4.61

4.97

4.8

2.5

5.9

2.4

e6/l

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

4.25

4.89

2.2

1.6

0.5

0.7

mg/l

0.61

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

10.09

4.85

2.4

1.0

—

(3015736) pH of Urine

111

4.21

4.83

4.8

3.0

—

(3021601) Nitrite [Presence] in Urine by Test strip

152

4.63

4.82

6.8

4.1

0.0

estimate

—

(3007164) IgA [Mass/volume] in Serum or Plasma

4.19

4.79

2.0

1.3

1.8

2.4

g/l

0.83

(40758558) Short blood count panel - Blood

4.12

4.75

14.1

7.5

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

4.41

4.70

3.0

2.3

9.8

133.9

ng/l

0.52

(3009261) Glucose [Presence] in Urine by Test strip

154

4.53

4.68

4.6

3.1

0.0

estimate

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

9.23

4.63

1.1

1.7

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

4.12

4.63

5.1

3.4

—

(3026782) Osmolality of Urine

4.13

4.45

3.6

2.3

602.7

508.2

mosm/kgh2o

0.55

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

4.05

4.34

4.6

2.2

1.7

e6/l

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

9.60

4.28

1.3

1.4

—

(3032080) INR in Blood by Coagulation assay

103

3.81

4.26

10.6

7.4

1.0

1.2

inr

0.68

(40768797) Stomach Pathology biopsy report

4.31

4.25

1.3

1.2

—

(3018095) Leukocytes [#/volume] in Urine

111

3.80

4.23

7.4

3.1

69.6

58.6

e6/l

0.06

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

11.71

4.18

1.4

1.3

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

13.70

3.89

1.0

1.4

—

(3002582) Erythrocytes [#/volume] in Urine

102

3.50

3.76

6.0

2.5

22.1

37.3

e6/l

0.30

(3007853) Bacteria identified in Skin by Aerobe culture

4.17

3.68

2.3

1.5

—

(3022145) Colonoscopy Study observation

4.33

3.63

1.1

1.3

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

11.41

3.62

1.3

1.2

—

(3003396) Base excess in Arterial blood by calculation

4.19

3.48

11.8

4.5

0.2

1.9

mmol/l

0.68

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

6.34

3.38

9.1

5.6

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

9.76

3.38

1.7

1.9

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

9.76

3.38

1.7

1.9

—

(3042936) Bacteria identified in Isolate by Culture

3.50

3.33

2.5

2.2

—

(3000492) Spirometry study

4.24

3.28

1.4

1.5

—

(3012516) Albumin [Mass/volume] in Urine

3.23

3.19

2.8

2.7

10.9

55.7

mg/l

—

(3037756) Immunofixation for Serum or Plasma

11.12

3.06

1.6

—

(3020682) Albumin/Creatinine [Ratio] in Urine

3.13

3.04

2.9

3.5

1.4

7.9

mg/mmol

—

(3021960) Folate [Moles/volume] in Serum or Plasma

3.18

2.88

1.9

1.5

16.9

20.0

nmol/l

0.54

(3020779) Urea [Moles/volume] in Serum or Plasma

4.50

2.88

8.3

7.9

9.0

7.0

mmol/l

—

(3024354) Oxygen [Partial pressure] in Venous blood

4.96

2.85

1.5

2.7

4.8

5.0

kpa

—

(3003327) Ova and parasites identified in Stool by Light microscopy

6.80

2.80

1.5

2.3

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

6.80

2.80

2.0

1.9

0.6

0.4

ug/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

3.12

2.79

1.7

2.0

—

(4035726)

4.31

2.77

1.3

1.2

—

(40760892) CBC W Ordered Manual Differential panel - Blood

3.06

2.71

3.5

5.0

—

(3052851) Hemolysis interference index of Serum or Plasma

6.17

2.64

2.3

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

7.92

2.62

1.4

1.3

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

7.92

2.62

2.6

3.4

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

7.92

2.62

1.4

1.6

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

104

2.80

2.59

4.5

3.2

12.8

23.6

ng/l

2.10

(4010399)

3.97

2.58

1.4

1.5

—

(3045414) Leukocytes [Presence] in Urine

6.14

2.28

1.6

1.4

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

6.14

2.28

2.4

2.0

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

6.14

2.28

1.2

1.4

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

6.14

2.28

3.0

1.8

80.2

104.0

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

4.21

2.26

5.9

3.9

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

4.82

2.24

1.2

2.7

121.7

131.4

g/l

—

(40761536) Microorganisms panel - Urine sediment

4.00

2.16

2.3

3.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

5.52

2.13

1.2

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

4.49

2.12

1.3

—

(36660697) Celiac disease serology panel - Serum

3.10

2.01

1.3

1.0

—

(3000494) Fungus identified in Specimen by Culture

2.98

2.01

2.6

1.4

—

(3034770) Mitochondria Ab [Titer] in Serum

5.01

2.00

1.0

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.90

1.92

1.2

1.9

—

(3026008) Bacteria identified in Urine by Culture

2.45

1.88

6.5

2.5

—

(3044640) Blood type and Crossmatch panel - Blood

2.32

1.73

4.9

2.4

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

3.91

1.66

1.2

2.4

1.8

2.0

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

3.91

1.66

1.2

1.1

—

(3020961) Endomysium IgA Ab [Titer] in Serum

3.91

1.66

1.2

1.1

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

3.33

1.65

1.2

2.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

2.29

1.49

5.1

2.3

—

(3044889) 12 lead EKG panel

235

2.31

1.45

5.7

3.0

—

(3029937) Albumin [Presence] in Urine by Test strip

2.04

1.21

4.8

3.6

0.0

estimate

—

(3022217) INR in Platelet poor plasma by Coagulation assay

2.60

1.19

64.6

20.9

—

1.4

—

(3019060) Gas panel - Arterial blood

2.57

1.12

3.8

4.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.08

1.03

1.1

1.7

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

0.00

1.02

0.0

1.6

—

78.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.80

0.85

2.8

2.6

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.00

0.82

0.0

1.1

—

(40761535) Cells panel - Urine sediment

1.89

0.68

6.8

3.0

—

(3013512) EKG study

1.66

0.63

5.8

3.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

120

1.55

0.58

5.3

3.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

150

1.50

0.54

7.0

3.9

—

(3009542) Hematocrit [Volume Fraction] of Blood

316

1.73

0.49

45.8

12.7

40.1

39.9

0.06

242

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.41

0.0

1.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.44

0.39

1.2

1.8

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.34

0.28

1.4

1.5

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.2

—

61.4

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.20

0.0

3.8

—

66.5

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

352

0.80

0.19

6.1

3.8

4.8

4.7

mmol/l

0.25

332

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

351

0.82

0.19

5.8

3.7

1.4

1.5

mmol/l

0.44

328

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

1.22

0.17

5.1

4.6

1.4

2.1

ug/l

—

(40768804) Tissue Pathology biopsy report

145

1.17

0.11

2.1

1.8

—

(3002256) Pathology report gross observation

1.13

0.10

1.4

1.2

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

340

1.20

0.08

5.3

3.3

2.0

1.2

mmol/l

2.05

316

(1761868) Lipid panel - Serum or Plasma

109

0.89

0.04

4.3

2.6

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.4

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.7

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.1

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

0.8

—

(4268621)

0.00

0.0

1.9

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.0

1.1

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.02

0.00

2.2

1.9

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.5

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

3.0

—

4.2

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.0

1.3

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

3.0

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.0

2.0

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.0

1.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

3.0

—

104.6

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.3

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.0

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.3

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.0

—

(3003694) ABO and Rh group [Type] in Blood

1.00

0.00

1.6

1.4

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

1.8

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.0

2.5

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

250

1.00

0.00

4.6

3.3

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.3

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.7

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.6

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.3

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.4

—

13.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint DRUGADVERS_CUSHI_SYNDR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have DRUGADVERS_CUSHI_SYNDR.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: DRUGADVERS_CUSHI_SYNDR – Drug-induced Cushing's syndrome

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Drug-induced Cushing's syndrome

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints