Unspecified hairloss

L12_HAIRLOSSNAS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-9 — 7040H\|7040X Hospital discharge: ICD-8 — 70401\|70406 Cause of death: ICD-9 — 7040H\|7040X Cause of death: ICD-8 — 70401\|70406 2 out of 7 registries used, show all original rules.	44
4. Check minimum number of events None	44
5. Include endpoints None	44
6. Filter based on genotype QC (FinnGen only)	44

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2

NAME	L12_HAIRLOSSNAS
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_9	7040H\|7040X
HD_ICD_8	70401\|70406
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_9	7040H\|7040X
COD_ICD_8	70401\|70406
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Unspecified hairloss based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	44	18	26
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	26.86	23.99	28.85

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

2.69

2.33

2.2

1.5

1.0

mg/l

0.56

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

3.08

2.30

5.1

2.5

19.9

6.9

umol/l

0.59

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

3.18

1.40

3.2

9.8

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

3.00

1.32

1.6

1.8

—

(3002032) Base excess in Venous blood by calculation

0.00

1.22

0.0

3.5

—

2.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

192

1.87

1.15

2.5

3.0

—

(3000492) Spirometry study

2.55

1.12

1.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

2.15

1.11

1.2

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

1.02

0.0

1.3

—

(3033658) Prothrombin time (PT) actual/Normal

1.81

0.92

7.1

3.4

85.9

87.3

0.08

(40768804) Tissue Pathology biopsy report

147

1.66

0.82

2.4

1.8

—

(3022621) pH of Urine by Test strip

2.32

0.79

4.6

1.8

—

(3042936) Bacteria identified in Isolate by Culture

1.69

0.76

1.4

2.0

—

(3002582) Erythrocytes [#/volume] in Urine

116

1.60

0.67

2.7

2.9

5.6

14.2

e6/l

1.89

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.73

0.66

1.1

1.6

—

(3019225) pH of Specimen

1.75

0.63

3.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

136

1.55

0.63

2.4

3.1

—

(1761868) Lipid panel - Serum or Plasma

144

0.60

0.63

2.9

3.1

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

0.62

0.0

3.2

—

24.8

—

(4034850)

0.00

0.62

0.0

11.2

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.62

0.0

3.2

—

50.9

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.62

0.0

1.5

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

1.88

0.61

2.7

10.3

129.5

123.5

g/l

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

0.61

0.0

2.1

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

0.00

0.60

0.0

2.7

—

1.9

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

121

1.51

0.54

4.8

2.5

49.9

29.9

u/l

0.58

110

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.58

0.54

4.8

4.0

3.2

117.2

ug/l

—

(36304419) Bacteria [Presence] in Urine

103

1.53

0.54

2.6

3.0

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

219

1.46

0.51

3.8

4.8

7.2

6.8

mmol/l

0.27

208

(3023368) Bacteria identified in Blood by Culture

1.50

0.49

3.4

4.3

—

(40768797) Stomach Pathology biopsy report

1.47

0.48

1.3

—

(3018095) Leukocytes [#/volume] in Urine

135

1.42

0.44

3.1

3.3

3.5

26.3

e6/l

2.17

(3022145) Colonoscopy Study observation

1.63

0.44

1.8

1.3

—

(4035726)

1.63

0.44

1.6

1.2

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.41

0.0

1.5

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

0.00

0.41

0.0

1.6

—

2.0

—

(42870588) Differential panel, method unspecified - Blood

118

1.41

0.41

7.7

4.5

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

246

1.38

0.39

3.7

3.2

66.6

58.1

u/l

0.28

228

(3044640) Blood type and Crossmatch panel - Blood

110

1.40

0.38

2.4

2.6

—

(3044889) 12 lead EKG panel

268

1.38

0.36

3.3

4.0

—

(3002256) Pathology report gross observation

1.35

0.34

1.5

1.2

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.41

0.33

2.0

1.9

14.2

13.9

umol/l

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

133

1.32

0.30

5.4

3.9

19.4

21.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

133

1.32

0.30

1.8

2.0

87.1

97.4

pmol/l

—

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.21

0.0

4.0

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

0.21

0.0

2.9

—

113.3

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.6

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

3.7

—

16.4

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.21

0.0

5.2

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.32

0.21

1.3

1.9

407.3

361.6

nmol/l

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

2.1

—

(3022313) Gas panel - Capillary blood

0.00

0.21

0.0

1.4

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.20

0.0

2.0

—

(40761511) CBC panel - Blood by Automated count

383

0.79

0.19

12.9

11.8

—

(3032080) INR in Blood by Coagulation assay

159

1.22

0.19

13.8

6.7

1.2

inr

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

300

1.24

0.18

8.9

7.2

90.8

79.6

u/l

0.63

281

(3037467) Urinalysis macro (dipstick) panel - Urine

239

1.21

0.18

5.3

3.8

—

(3041096) Erythrocytes [Presence] in Urine by Automated

0.82

0.15

2.9

3.8

—

(40758558) Short blood count panel - Blood

1.23

0.15

5.5

8.1

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

1.23

0.15

2.4

2.6

0.5

0.7

ug/l

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

355

0.81

0.14

12.2

12.4

79.0

80.1

ml/min/173m2

0.12

291

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

163

1.18

0.14

4.2

4.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.07

0.07

3.0

2.5

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.07

0.07

4.0

3.6

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

208

1.12

0.07

7.2

5.9

17.9

10.2

umol/l

1.04

196

(3013512) EKG study

111

1.11

0.04

3.0

3.9

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

152

1.08

0.03

3.1

3.7

18.6

42.3

ng/l

—

116

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

136

0.94

0.01

3.8

4.1

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

131

0.99

0.00

3.2

2.5

45.2

54.7

u/l

0.80

122

(3009542) Hematocrit [Volume Fraction] of Blood

325

1.06

0.00

15.2

15.0

42.0

40.6

0.86

228

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

4.3

—

4.1

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

4.3

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

1.4

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.3

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.7

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.9

—

90.3

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.0

2.3

—

(1616796) Gas panel - Central venous blood

0.00

0.0

1.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

0.84

0.00

1.0

1.7

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.0

2.0

—

1.5

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

4.3

—

104.7

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(3016879) Cocaine [Presence] in Urine

0.00

0.0

1.0

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.0

1.0

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.2

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

1.1

—

(44806118)

0.00

0.0

1.8

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3027008) Opiates [Presence] in Urine

0.00

0.0

1.0

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.0

4.3

—

1.6

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3027456) Digoxin [Moles/volume] in Serum or Plasma

0.00

0.0

3.2

—

0.8

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

77.6

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

2.0

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.4

—

(44790049)

0.00

0.0

1.8

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.0

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

1.3

—

33.5

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

1.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

0.92

0.00

2.4

6.6

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.0

1.0

—

(44790048)

0.00

0.0

1.8

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.0

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

1.04

0.00

1.2

1.3

—

6.1

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.02

0.00

2.4

1.9

2.5

2.4

g/l

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.2

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

2.6

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.2

—

(44790047)

0.00

0.0

1.8

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

3.8

—

3.4

—

(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3026008) Bacteria identified in Urine by Culture

0.91

0.00

3.2

2.7

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.8

—

(3045788) Cell count panel - Pleural fluid

0.00

0.0

1.4

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.0

1.0

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.0

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.0

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.9

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

2.0

—

(3002385) Erythrocyte distribution width [Ratio]

300

1.00

0.00

15.2

16.3

13.1

13.8

1.89

294

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.0

4.3

—

10.1

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.0

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

3.3

—

(3003694) ABO and Rh group [Type] in Blood

0.91

0.00

1.3

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.0

1.0

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

-0.00

0.0

3.1

—

4.8

—

(3010421) pH of Blood

0.00

-0.00

0.0

3.3

—

7.4

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

-0.00

0.0

1.2

—

(3003181) Sodium [Moles/volume] in Urine

0.00

-0.00

0.0

1.6

—

66.2

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

-0.00

0.0

3.1

—

8.4

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: L12_HAIRLOSSNAS – Unspecified hairloss

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Unspecified hairloss

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Unspecified hairloss (L12_HAIRLOSSNAS)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Relationships between endpoints