Neonatal aspiration syndromes

P16_NEONTAL_ASPIRATI_SYNDR

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P24 Cause of death: ICD-10 — P24 2 out of 7 registries used, show all original rules.	45
4. Check minimum number of events None	45
5. Include endpoints None	45
6. Filter based on genotype QC (FinnGen only)	45

Control definitions (FinnGen only)

Control exclude: P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P2
Name in latin: Syndroma aspirationis neonatorum

NAME	P16_NEONTAL_ASPIRATI_SYNDR
CONTROL_EXCLUDE	P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P24
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P24
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Neonatal aspiration syndromes based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	3059	1560	1499
Only index persons	1802	902	900
Unadjusted period prevalence (%)
Whole population	0.04	0.04	0.04
Only index persons	0.03	0.03	0.03
Median age at first event (years)
Whole population	-	0.00	0.00
Only index persons	0.00	0.00	0.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	45	29	16
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	0.00	0.00	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768797) Stomach Pathology biopsy report

2.99

1.32

1.2

1.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

107

0.40

1.21

1.2

1.9

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

144

0.46

1.21

1.8

2.3

—

(1761868) Lipid panel - Serum or Plasma

2.02

1.05

1.5

1.6

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

1.01

0.0

1.2

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

0.00

0.99

0.0

1.2

—

21.4

—

(3005322) IgE [Units/volume] in Serum or Plasma

2.08

0.88

1.3

1.4

170.8

791.6

u/ml

—

(3023368) Bacteria identified in Blood by Culture

1.85

0.86

2.9

5.9

—

(3011288) Drugs identified in Urine by Screen method

1.81

0.84

1.6

3.2

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.81

0.0

1.6

—

(3016879) Cocaine [Presence] in Urine

1.79

0.80

1.3

2.7

—

(3027944) Amphetamines [Presence] in Urine

1.86

0.80

1.6

2.7

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

2.03

0.73

19.4

27.6

0.9

1.0

mg/l

—

(3000764) Benzodiazepines [Presence] in Urine

1.79

0.72

1.6

2.6

—

(3027008) Opiates [Presence] in Urine

1.79

0.72

1.6

2.5

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

1.74

0.70

4.0

6.3

24.1

24.3

mmol/l

—

(3028300) Cannabinoids [Presence] in Urine

1.76

0.68

1.6

2.6

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.77

0.67

1.4

2.9

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.62

0.0

1.9

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.62

0.0

1.7

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.62

0.0

1.7

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.62

0.0

1.3

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.61

0.0

1.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.82

0.60

1.3

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

140

0.63

0.54

2.1

2.6

—

(3022313) Gas panel - Capillary blood

1.66

0.52

4.0

6.0

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.55

0.51

1.6

2.1

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.54

0.50

1.0

1.1

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.61

0.48

1.7

1.9

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

188

0.70

0.46

1.8

2.1

—

(3009542) Hematocrit [Volume Fraction] of Blood

339

1.51

0.44

19.0

13.0

38.3

39.4

0.30

288

(40761536) Microorganisms panel - Urine sediment

1.63

0.44

1.8

4.3

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.42

0.0

1.4

—

(3000330) Specific gravity of Urine by Test strip

0.00

0.42

0.0

1.7

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.42

0.0

1.4

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.42

0.0

1.2

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.42

0.0

1.4

—

(3045414) Leukocytes [Presence] in Urine

0.00

0.42

0.0

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.42

0.0

1.4

—

(40761535) Cells panel - Urine sediment

0.00

0.42

0.0

2.4

—

(3042936) Bacteria identified in Isolate by Culture

1.53

0.42

1.4

1.8

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

0.00

0.41

0.0

2.7

—

0.2

—

(42870588) Differential panel, method unspecified - Blood

129

1.37

0.37

12.1

9.4

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

180

0.75

0.32

2.3

2.6

1.2

mmol/l

0.10

170

(36304419) Bacteria [Presence] in Urine

1.39

0.32

3.1

5.2

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.28

0.29

2.9

3.8

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

306

0.78

0.27

15.8

11.7

139.1

139.6

mmol/l

0.21

296

(3015377) Calcium [Moles/volume] in Serum or Plasma

1.23

0.27

2.3

2.4

mmol/l

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

305

0.78

0.26

15.0

11.7

4.0

3.9

mmol/l

0.69

294

(40761511) CBC panel - Blood by Automated count

352

0.77

0.24

6.5

7.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.28

0.23

2.2

1.9

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

0.00

0.21

0.0

11.7

—

0.3

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.0

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.2

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.21

0.0

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.4

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.4

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

1.8

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

223

0.81

0.21

7.5

6.7

115.9

116.1

ml/min/173m2

0.01

156

(3009445) Proteinase 3 Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.21

0.0

1.4

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.0

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.4

—

(3000991) Gas panel - Venous blood

1.23

0.21

29.3

15.8

—

(3025941) Bacteria identified in Stool by Culture

0.00

0.20

0.0

1.2

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

192

0.82

0.20

2.0

2.3

1.4

mmol/l

0.30

180

(3044640) Blood type and Crossmatch panel - Blood

1.28

0.19

2.8

3.7

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.28

0.19

3.3

4.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

148

0.83

0.15

1.8

2.8

—

(3018095) Leukocytes [#/volume] in Urine

113

1.21

0.15

3.3

5.8

8.2

35.5

e6/l

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

167

0.85

0.13

2.4

2.6

31.4

35.3

mmol/mol

2.88

151

(3044889) 12 lead EKG panel

136

0.84

0.13

3.0

2.0

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

196

0.86

0.12

2.0

2.4

4.4

4.3

mmol/l

0.16

184

(3003694) ABO and Rh group [Type] in Blood

127

1.15

0.09

1.4

1.7

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.08

0.09

6.0

12.9

24.2

25.1

mmol/l

—

(3012544) pH of Venous blood

1.08

0.09

5.8

11.0

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.80

0.09

1.0

—

(36660697) Celiac disease serology panel - Serum

0.75

0.09

1.0

1.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

383

0.95

0.08

4.6

3.7

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

203

0.89

0.08

22.0

10.1

2.9

3.9

e9/l

2.31

175

(40768804) Tissue Pathology biopsy report

0.79

0.08

1.5

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

128

1.14

0.08

3.4

4.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.11

0.08

1.2

3.5

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

100

0.88

0.07

1.4

2.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

103

0.84

0.07

1.2

3.7

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

191

0.90

0.06

2.1

2.4

2.8

2.6

mmol/l

0.70

176

(40758558) Short blood count panel - Blood

101

1.12

0.04

16.8

10.0

—

(3037467) Urinalysis macro (dipstick) panel - Urine

201

1.08

0.04

3.8

4.6

—

(3015736) pH of Urine

107

0.92

0.02

1.4

3.4

—

(3002030) Lymphocytes/100 leukocytes in Blood

191

0.99

0.00

13.6

8.8

36.9

34.1

0.56

185

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

167

1.03

0.00

2.2

3.4

20.7

24.4

u/l

0.39

161

(3006504) Eosinophils/100 leukocytes in Blood

177

1.03

0.00

14.2

9.3

3.2

3.1

0.06

167

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.07

0.00

1.6

1.9

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

105

1.06

0.00

3.1

5.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

144

0.96

0.00

1.1

1.6

1.4

1.6

g/l

—

(3018010) Neutrophils/100 leukocytes in Blood

186

1.04

0.00

13.6

8.7

45.8

51.2

0.93

178

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.0

1.6

—

1.1

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.0

1.4

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.0

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.0

6.8

—

4.9

—

(3024928) Oxygen saturation in Venous blood

0.00

0.0

28.2

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.0

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.0

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.0

2.7

—

53.1

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.0

1.9

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.2

—

(4268621)

0.00

0.0

2.0

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.0

5.0

—

1.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

340

1.00

0.00

8.9

10.1

21.8

22.7

mg/l

0.05

236

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

0.0

1.0

—

(3019069) Monocytes/100 leukocytes in Blood

180

1.00

0.00

14.3

9.2

9.3

8.1

1.45

172

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.1

—

(42528717) Cashew nut recombinant (rAna o) 3 IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

3.1

—

(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood

0.00

0.0

1.0

—

18.8

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

6.0

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.4

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.0

3.8

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.0

—

29.7

—

(3018405) Lactate [Moles/volume] in Arterial blood

0.00

0.0

2.1

—

1.3

—

(40768446) Kidney Pathology biopsy report

0.00

0.0

2.0

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

0.0

1.0

—

(4198724)

0.00

0.0

3.4

—

(3021706) Oxygen [Partial pressure] in Arterial cord blood

0.00

0.0

1.0

—

3.6

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

0.0

2.1

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

0.0

25.1

—

77.2

—

(3010375) cycloSPORINE [Mass/volume] in Blood

0.00

0.0

35.8

—

150.0

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

0.00

0.0

2.6

—

1.9

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

6.6

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.0

10.1

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

0.0

1.1

—

213.1

—

(3041806) Other cells [#/volume] in Blood by Manual count

0.00

0.0

1.1

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.0

1.6

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

2.3

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.0

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3022229) Phosphate [Moles/volume] in Urine

0.00

0.0

2.6

—

9.4

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

0.0

1.0

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

0.0

4.0

—

47.1

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.0

6.8

—

10.1

—

(44790048)

0.00

0.0

2.5

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

1.01

0.00

1.3

2.4

2.2

2.5

mg/l

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(4062490)

0.00

0.0

1.0

—

(3003932) Carbon dioxide [Partial pressure] in Arterial cord blood

0.00

0.0

1.0

—

7.1

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

3.2

—

(44806118)

0.00

0.0

2.5

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

0.0

4.0

—

3.0

—

(3011648) Oxygen content in Venous blood

0.00

0.0

32.6

—

12.6

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.0

2.9

—

2.4

—

(3020891) Body temperature

0.00

0.0

3.6

—

(3020393) Adenovirus Ag [Presence] in Stool

0.00

0.0

1.3

—

(3006598) pH of Arterial cord blood

0.00

0.0

1.0

—

(4034850)

0.00

0.0

6.6

—

(3000504) BK virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

6.2

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

1.00

0.00

2.3

2.5

—

3328.2

u/l

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

2.1

—

94.2

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

6.9

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

0.3

—

(42870560) Thyrotropin [Units/volume] in Cord blood

0.00

0.0

1.0

—

8.9

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

0.0

1.0

—

92.2

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.0

—

(1616796) Gas panel - Central venous blood

0.00

0.0

12.2

—

(3042299) inFLIXimab [Mass/volume] in Serum or Plasma

0.00

0.0

5.8

—

7.7

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.0

—

(44790047)

0.00

0.0

2.5

—

(44790049)

0.00

0.0

2.5

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

0.0

1.9

—

(3010421) pH of Blood

0.00

0.0

6.8

—

7.4

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_NEONTAL_ASPIRATI_SYNDR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_NEONTAL_ASPIRATI_SYNDR.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_NEONTAL_ASPIRATI_SYNDR – Neonatal aspiration syndromes

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Neonatal aspiration syndromes

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints