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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_EPENDYDOMA_EXALLC for full statistics.

Ependymoma

C3_EPENDYDOMA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 939[1-3]
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

60

4. Check minimum number of events

None

60

5. Include endpoints

None

60

6. Filter based on genotype QC (FinnGen only)

60

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF9

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 60 36 24
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 46.43 43.60 50.68

-FinnGen-

Age distribution of first events

01030405060700123456789101112AgeIndividuals

-FinnGen-

Year distribution of first events

197019751980198520002005201020152020202302468101214161820YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
54
Matched controls
539
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
9391/3-C72.0
ICD-O-3
Ependymoma, NOS, of spinal cord
+∞
32.6
28
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
+∞
16.5
15
*
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
+∞
16.5
15
*
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
110.8
15.5
16
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
18.1
14.4
23
21
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
+∞
14.2
13
*
C71.74
ICD-10 Finland
Malignant tumor of the brainstem ependyoma
+∞
11.9
11
*
C72.09
ICD-10 Finland
Malignant tumor of the spinal cord other histology
+∞
11.9
11
*
C72.00
ICD-10 Finland
Malignant tumor of the spinal cord without histology
+∞
10.8
10
*
C72.01
ICD-10 Finland
Malignant tumor of the spinal cord grade II glioma
+∞
10.8
10
*
H02AB02
ATC
dexamethasone; systemic
12.0
10.6
20
25
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
+∞
9.7
9
*
C71.51
ICD-10 Finland
Malignant tumor of cerebral ventricle ependymoma
+∞
9.7
9
*
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
60.1
9.0
10
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
105.9
8.7
9
*
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
+∞
8.5
8
*
D43.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal cord
+∞
8.5
8
*
9391/3-C71.7
ICD-O-3
Ependymoma, NOS, of brain stem
+∞
8.5
8
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
7.7
8.4
21
41
TAB00
NOMESCO Finland
Lumbar puncture
27.0
8.4
11
5
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
52.9
8.0
9
*
M03BX01
ATC
baclofen; systemic
92.2
7.6
8
*
D33.43
ICD-10 Finland
Spinal cord
+∞
7.5
7
*
D33.41
ICD-10 Finland
Myxopapillary epndymoma of the spinal cord (grade I)
+∞
6.4
6
*
9391/3-C71.5
ICD-O-3
Ependymoma, NOS, of ventricle, NOS
+∞
6.4
6
*
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
+∞
6.4
6
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
6.4
6
*
D33.4
ICD-10 Finland
Benign neoplasm: Spinal cord
+∞
6.4
6
*
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
+∞
6.4
6
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
6.4
6
*
130
Kela drug reimbursment
Malignant tumour
9.9
6.2
12
15

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
22
35
9.35
14.44
1.5
1.6
—
—
—
0
0
24
45
8.22
13.61
6.2
7.2
0.51
1.51
mmol/l
1.15
15
35
11
15
8.76
7.83
3.1
3.7
—
—
—
0
0
16
42
4.83
6.00
8.2
14.7
23.88
24.88
mmol/l
0.71
16
42
8
5
18.12
5.57
3.7
4.6
—
—
—
0
0
32
158
3.20
4.68
3.2
2.6
—
—
—
0
0
34
187
2.89
3.92
3.2
1.9
—
—
—
0
0
29
150
2.81
3.71
3.3
3.9
9.51
24.76
e6/l
0.81
24
117
15
53
3.44
3.67
8.2
10.6
—
—
—
0
0
22
102
2.83
3.41
2.6
2.7
550.09
566.34
mosm/kgh2o
0.14
22
85
22
107
2.67
3.07
2.5
3.3
1.94
4.75
e6/l
2.27
22
97
26
139
2.54
2.99
3.5
3.3
—
—
—
0
0
6
9
7.25
2.94
2.0
5.2
—
—
—
0
0
5
6
8.94
2.80
1.8
5.2
27.40
27.83
%
—
5
6
28
160
2.41
2.75
3.9
6.9
1.04
1.11
inr
—
7
52
5
7
7.65
2.60
1.8
4.3
—
—
—
0
0
15
68
2.61
2.35
5.8
3.2
29.87
30.10
s
0.07
15
68
6
13
5.00
2.33
4.7
5.6
16.33
21.28
nmol/l
—
6
13
20
105
2.36
2.31
4.5
3.9
—
—
—
0
0
8
24
3.68
2.27
6.4
4.8
—
—
—
0
0
5
9
5.94
2.26
1.8
4.8
19.80
9.78
%
—
5
9
29
184
2.12
2.09
4.0
4.4
36.13
37.35
e6/l
0.02
24
122
36
249
2.11
2.06
10.0
7.4
8.83
10.29
umol/l
1.00
36
234
22
126
2.18
2.05
4.1
2.7
—
—
—
0
0
0
48
0.00
1.79
0.0
1.5
—
—
—
0
0
27
175
1.99
1.77
12.2
7.3
—
—
—
0
0
12
56
2.43
1.75
7.8
7.9
—
—
—
0
0
5
18
2.93
1.31
1.8
2.1
—
—
—
0
0
5
18
2.93
1.31
4.2
2.6
—
—
—
0
0
20
129
1.83
1.27
1.2
1.6
—
—
—
0
0
11
59
2.06
1.16
2.0
2.8
220.09
326.15
nmol/l
1.68
11
54
32
245
1.66
1.08
22.1
9.5
0.00
0.00
e9/l
0.50
27
191
5
22
2.38
1.05
3.8
4.4
—
—
—
0
0
55
499
2.22
1.01
18.9
13.3
26.52
18.45
mg/l
0.86
50
373
0
30
0.00
1.00
0.0
1.2
—
—
—
0
0
12
183
0.57
0.92
3.6
2.3
—
—
—
0
0
8
46
1.85
0.86
1.6
1.9
—
—
—
0
0
0
24
0.00
0.81
0.0
1.8
—
—
—
0
0
0
25
0.00
0.81
0.0
1.7
—
—
—
0
0
0
25
0.00
0.81
0.0
1.7
—
—
—
0
0
0
26
0.00
0.80
0.0
1.7
—
—
—
0
0
9
55
1.75
0.78
2.3
5.7
1.36
1.75
%
—
9
50
22
164
1.54
0.78
4.0
3.5
2.36
2.36
mmol/l
0.12
22
146
10
61
1.77
0.74
1.9
1.6
—
—
—
0
0
39
334
1.48
0.68
6.1
4.4
—
—
—
0
0
5
29
1.79
0.65
1.6
1.2
—
—
—
0
0
8
51
1.65
0.64
1.1
1.2
—
—
—
0
0
0
19
0.00
0.61
0.0
1.7
—
—
—
0
0
32
268
1.42
0.60
16.5
7.2
0.03
0.04
e9/l
1.28
27
235
0
23
0.00
0.59
0.0
1.8
—
—
—
0
0
6
36
1.74
0.59
2.2
2.6
—
—
—
0
0
9
59
1.62
0.58
2.0
1.7
—
—
—
0
0
17
127
1.47
0.58
1.8
4.6
7.98
7.61
mmol/l
0.08
17
111
6
37
1.69
0.57
1.3
1.5
—
—
—
0
0
20
155
1.44
0.57
2.8
4.1
15.30
42.95
ng/l
—
10
101
6
38
1.64
0.56
9.2
14.6
—
—
—
0
0
10
67
1.59
0.54
1.7
2.9
24.49
23.82
%
—
10
59
21
257
0.72
0.52
6.3
4.0
0.00
0.00
estimate
—
7
42
21
253
0.74
0.46
7.0
5.5
0.00
0.00
estimate
—
8
46
16
200
0.73
0.44
4.3
3.9
—
—
—
0
0
0
15
0.00
0.42
0.0
1.3
—
242.00
—
0
5
0
15
0.00
0.42
0.0
1.7
—
—
—
0
0
0
15
0.00
0.42
0.0
1.5
—
—
—
0
0
0
15
0.00
0.42
0.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
4.6
—
18.63
—
0
11
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.41
0.0
2.9
—
—
—
0
0
20
166
1.31
0.36
2.1
1.8
92.40
102.61
pmol/l
—
10
84
11
141
0.73
0.34
8.3
3.9
—
—
—
0
0
35
315
1.27
0.33
3.8
3.3
—
—
—
0
0
18
149
1.30
0.33
19.3
8.4
—
—
—
0
0
10
75
1.40
0.32
1.0
1.2
—
—
—
0
0
22
254
0.79
0.32
6.1
4.0
0.00
0.00
estimate
—
8
46
42
387
1.28
0.32
4.9
4.2
14.54
14.66
pmol/l
0.11
42
352
5
73
0.66
0.28
1.2
1.6
—
—
—
0
0
10
78
1.34
0.26
5.1
2.6
2.47
2.46
mmol/l
—
10
67
10
125
0.76
0.26
3.6
3.5
—
—
—
0
0
5
38
1.34
0.24
5.2
5.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
15
130
1.21
0.18
6.5
4.5
0.00
0.00
estimate
—
8
45
8
67
1.22
0.18
1.4
1.6
—
—
—
0
0
13
112
1.21
0.16
3.7
5.3
0.75
2.18
ug/l
5.71
13
98
7
87
0.78
0.16
2.0
1.9
451.86
477.00
pmol/l
—
7
74
6
53
1.15
0.09
1.2
1.4
—
—
—
0
0
11
123
0.87
0.09
4.1
3.5
—
—
—
0
0
5
64
0.76
0.08
1.4
1.2
—
—
—
0
0
10
112
0.87
0.08
1.5
2.0
—
—
—
0
0
10
108
0.91
0.03
9.3
5.7
—
—
—
0
0
13
138
0.93
0.03
3.5
1.5
1.83
2.20
g/l
—
8
79
47
471
0.99
0.00
27.3
14.5
40.12
39.60
%
0.26
35
372
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
12.52
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
67
0.88
0.00
3.5
2.8
0.67
0.86
ug/l
—
6
44
0
5
0.00
0.00
0.0
24.8
—
201.20
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
4.6
—
104.60
—
0
5
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
6.0
—
1.76
—
0
8
0
5
0.00
0.00
0.0
5.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
88
0.90
0.00
1.4
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
0
5
0.00
0.00
0.0
4.6
—
4.14
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
5.0
—
0.83
—
0
6
0
7
0.00
0.00
0.0
2.6
—
2.03
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
13.28
—
0
5
0
5
0.00
0.00
0.0
1.2
—
110.38
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
87.6
—
145.60
—
0
5
5
59
0.83
0.00
1.8
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
4.1
—
8.50
—
0
7
0
5
0.00
0.00
0.0
4.6
—
—
—
0
0
0
7
0.00
0.00
0.0
3.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
4.1
—
4.83
—
0
7
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
14.89
—
0
9
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_EPENDYDOMA – Ependymoma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).