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This is a non-core endpoint: only basic statistics are computed.

Disorders of multiple cranial nerves

DOID Endpoint Browser

G6_DISMULTIP

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G52.7
  • Hospital discharge: ICD-9 — 3526
  • Cause of death: ICD-10 — G52.7
  • Cause of death: ICD-9 — 3526

2 out of 7 registries used, show all original rules.

32

4. Check minimum number of events

None

32

5. Include endpoints

None

32

6. Filter based on genotype QC (FinnGen only)

32

Control definitions (FinnGen only)

Control exclude
G6_NERPLEX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G52
Name in latin
Morbositates nervorum cranialium multorum

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 255 133 119
Only index persons 207 113 94
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 52.61 49.79 55.66
Only index persons 50.65 48.32 53.45

-FinnGen-

Key figures

All Female Male
Number of individuals 32 16 16
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 51.04 47.98 54.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
7
5
17.30
4.81
1.3
1.2
mg/l
469.9
592.2
—
7
5
(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid
5
5
11.49
3.08
1.4
1.4
e6/l
5.4
3.2
—
5
5
(3016543) Leukocytes [#/volume] in Cerebral spinal fluid
5
5
11.49
3.08
1.4
1.4
e6/l
1.4
4.0
—
5
5
(3017446) Testosterone [Moles/volume] in Serum or Plasma
7
17
4.95
2.52
3.0
1.6
nmol/l
11.7
12.6
—
7
17
(3018677) aPTT in Platelet poor plasma by Coagulation assay
10
37
3.48
2.36
1.7
2.0
s
27.5
28.3
—
10
37
(3019060) Gas panel - Arterial blood
6
20
3.44
1.67
7.8
29.0
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
10
49
2.51
1.40
4.3
3.1
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
5
18
3.09
1.34
1.0
2.2
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
10
53
2.29
1.17
2.5
6.3
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
20
141
2.12
1.15
5.5
8.9
mmol/l
6.6
6.6
0.03
20
133
(3018010) Neutrophils/100 leukocytes in Blood
17
114
2.05
1.11
5.6
5.8
%
61.7
56.2
0.99
17
105
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
12
177
0.48
1.09
1.9
3.0
—
—
—
0
0
(40758558) Short blood count panel - Blood
11
63
2.14
1.07
8.3
6.8
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
17
116
1.99
1.04
6.3
11.2
mmol/l
1.2
1.2
0.48
17
101
(3013650) Neutrophils [#/volume] in Blood by Automated count
20
145
2.01
1.02
11.2
10.1
e9/l
4.7
3.9
1.19
20
122
(3033658) Prothrombin time (PT) actual/Normal
10
56
2.14
1.02
3.8
4.4
%
89.1
94.7
—
10
56
(3015736) pH of Urine
14
90
1.99
1.00
2.9
3.3
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
17
118
1.94
0.97
7.2
5.4
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
13
84
1.92
0.90
2.8
2.3
u/l
120.8
370.3
0.60
13
78
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
6
32
2.07
0.87
2.3
2.6
e6/l
0.2
0.9
—
6
18
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
5
25
2.18
0.76
1.2
1.6
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
13
88
1.80
0.76
2.7
3.0
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
16
116
1.76
0.74
5.9
6.2
%
26.2
28.2
0.32
16
107
(3010813) Leukocytes [#/volume] in Blood
27
293
0.50
0.72
34.7
22.1
e9/l
7.1
6.4
1.26
27
288
(3007461) Platelets [#/volume] in Blood
27
293
0.50
0.72
34.8
22.1
e9/l
264.7
244.0
0.75
27
288
(3000494) Fungus identified in Specimen by Culture
5
27
2.00
0.72
5.8
2.0
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
24
269
0.57
0.67
25.1
14.6
—
—
—
0
0
(3044889) 12 lead EKG panel
22
179
1.73
0.64
4.5
3.6
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
11
74
1.74
0.64
2.5
2.9
mmol/l
7.5
7.3
0.05
11
60
(3017181) Myelocytes/100 leukocytes in Blood
0
20
0.00
0.63
0.0
4.9
—
0.6
—
0
8
(3019069) Monocytes/100 leukocytes in Blood
15
113
1.62
0.57
6.1
6.4
%
7.0
8.9
2.38
15
103
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
6
39
1.66
0.56
1.2
1.9
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
13
97
1.57
0.50
3.5
3.5
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
20
165
1.57
0.50
4.7
4.4
—
78.2
—
0
6
(3019550) Sodium [Moles/volume] in Serum or Plasma
24
265
0.62
0.48
26.2
19.3
mmol/l
139.7
139.8
0.08
24
258
(3000850) Epithelial cells [#/volume] in Urine
8
55
1.60
0.48
2.5
3.0
e6/l
0.9
2.7
—
8
50
(3023103) Potassium [Moles/volume] in Serum or Plasma
24
264
0.64
0.48
26.2
19.4
mmol/l
4.0
4.0
0.30
24
257
(3002256) Pathology report gross observation
5
31
1.72
0.45
1.2
1.2
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
5
33
1.61
0.43
2.4
1.5
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
0
15
0.00
0.42
0.0
6.9
—
24.0
—
0
15
(3000991) Gas panel - Venous blood
0
16
0.00
0.42
0.0
13.6
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
0
17
0.00
0.42
0.0
5.4
—
0.0
—
0
7
(3021440) Promyelocytes/100 leukocytes in Blood
0
18
0.00
0.41
0.0
5.2
—
0.1
—
0
7
(42870588) Differential panel, method unspecified - Blood
10
73
1.54
0.41
7.8
6.0
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
14
111
1.46
0.39
6.5
5.9
%
2.8
2.7
0.06
14
100
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
6
42
1.53
0.38
1.0
1.4
—
—
—
0
0
(3012095) Magnesium [Moles/volume] in Serum or Plasma
6
44
1.45
0.37
2.8
5.4
mmol/l
0.8
0.8
—
6
44
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
10
76
1.46
0.33
1.6
1.8
mmol/l
1.3
1.3
—
10
68
(36304419) Bacteria [Presence] in Urine
9
71
1.37
0.30
3.0
2.6
—
—
—
0
0
(3013512) EKG study
9
75
1.28
0.28
4.4
4.3
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
23
208
1.37
0.25
10.9
8.2
u/l
70.1
80.4
1.21
23
198
(46235355) HIV 1 and 2 tests - Meaningful Use set
5
37
1.41
0.25
1.2
1.5
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
5
37
1.41
0.25
9.4
2.9
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
27
282
0.73
0.24
15.7
11.0
u/l
28.3
24.6
0.46
27
273
(3022096) Basophils/100 leukocytes in Blood
13
109
1.32
0.23
6.9
6.1
%
0.7
0.6
0.19
13
98
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
13
109
1.32
0.23
5.5
3.7
ng/l
9.7
26.0
—
8
75
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
12
100
1.32
0.22
2.3
1.9
pmol/l
105.1
95.8
—
6
46
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
0
10
0.00
0.22
0.0
3.1
—
1.0
—
0
10
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
10
0.00
0.22
0.0
1.6
—
—
—
0
0
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
0
10
0.00
0.22
0.0
3.1
—
0.7
—
0
10
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
6.4
—
616.4
—
0
12
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
10
82
1.32
0.20
1.9
2.7
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
13
111
1.29
0.20
2.1
1.9
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
8
66
1.28
0.19
3.4
3.0
umol/l
262.5
14872.6
—
8
61
(3030467) Casts [#/volume] in Urine by Automated count
8
67
1.26
0.19
3.3
2.8
e6/l
0.0
0.4
—
8
52
(3002582) Erythrocytes [#/volume] in Urine
9
76
1.26
0.18
2.9
3.3
e6/l
24.1
884.8
—
9
61
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
9
81
1.15
0.17
2.8
3.4
u/l
49.4
52.8
—
9
74
(1761868) Lipid panel - Serum or Plasma
9
104
0.81
0.16
2.6
2.6
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
19
176
1.20
0.11
7.0
4.4
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
18
188
0.90
0.03
5.6
3.3
u/l
48.7
49.9
0.04
18
177
(3003338) MCHC [Mass/volume]
22
223
0.96
0.00
38.2
19.3
g/l
333.7
331.7
0.58
22
223
(3023368) Bacteria identified in Blood by Culture
7
71
0.98
0.00
4.6
5.2
—
—
—
0
0
(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
17.4
—
0
5
(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
2.2
—
239.6
—
0
5
(3010421) pH of Blood
0
8
0.00
0.00
0.0
5.5
—
7.4
—
0
8
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
0
5
0.00
0.00
0.0
8.2
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
6
63
0.94
0.00
2.2
2.6
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
0
7
0.00
0.00
0.0
4.9
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
0
7
0.00
0.00
0.0
3.6
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
0
8
0.00
0.00
0.0
5.4
—
9.1
—
0
8
(40768793) Breast Pathology biopsy report
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.6
—
3.9
—
0
5
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
0
8
0.00
0.00
0.0
5.4
—
5.0
—
0
8
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
7
75
0.91
0.00
2.3
3.4
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
7
69
1.02
0.00
3.3
2.8
—
—
—
0
0
(1616796) Gas panel - Central venous blood
0
6
0.00
0.00
0.0
6.5
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
6
60
1.00
0.00
1.5
1.5
nmol/l
27.8
26.0
—
6
50
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021387) Prolactin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
587.4
—
0
5
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.2
—
13.7
—
0
6

Mortality – FinRegistry

↥

Association

Association between endpoint G6_DISMULTIP and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have G6_DISMULTIP.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: G6_DISMULTIP – Disorders of multiple cranial nerves

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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