Use of pergolide

PDMED_PERGOLIDE

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Medicine purchases: ATC — N04BC02 1 out of 7 registries used, show all original rules.	89
4. Check minimum number of events Min. number of events 3	89
5. Include endpoints None	89
6. Filter based on genotype QC (FinnGen only)	89

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze: DF2

NAME	PDMED_PERGOLIDE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC	N04BC02
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Use of pergolide based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	89	31	58
Unadjusted period prevalence (%)	0.02	0.01	0.03
Median age at first event (years)	60.96	56.73	63.23

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
84: Matched controls
838

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

N04BC02

ATC

pergolide; oral

+∞

118.9

110

Kela drug reimbursment

Parkinson's disease and comparable movement disrorders

736.6

90.1

G20

ICD-10 Finland

Parkinson disease

387.9

82.0

N04BA02

ATC

levodopa and decarboxylase inhibitor; oral

380.5

81.3

N04BD01

ATC

selegiline; oral

680.3

80.2

N04BX02

ATC

entacapone; oral

345.8

51.2

N04BA03

ATC

levodopa, decarboxylase inhibitor and COMT inhibitor; oral

197.9

47.8

N04BC05

ATC

pramipexole; oral

46.5

44.9

N04BB01

ATC

amantadine; oral

75.8

30.2

N04BD02

ATC

rasagiline; oral

123.1

25.3

F02.39*G20

ICD-10 Finland

Dementia in Parkinson's disease without information on additional symptoms

174.9

25.1

193

Kela drug reimbursment

Rasagiline

311.2

23.9

N87

ICPC

Parkinsonism

58.1

21.9

N04BC04

ATC

ropinirole; oral

58.1

21.9

3320A

ICD-9 Finland

Parkinson's disease, Paralysis agitans

+∞

21.8

G02CB01

ATC

bromocriptine; systemic

80.5

17.6

AAG20

NOMESCO Finland

Stereotactic intracranial implantation of electrodes

+∞

13.9

N04BC06

ATC

cabergoline; oral (dopamine agonists)

75.7

12.0

H02AA02

ATC

fludrocortisone; oral

50.5

11.3

N04AA02

ATC

biperiden; systemic

25.6

11.1

N03AE01

ATC

clonazepam; systemic

9.2

10.7

AEA50

NOMESCO Finland

Adjustment of implanted neurostimulator

+∞

10.6

N05AH04

ATC

quetiapine; oral

7.0

9.6

N04BC01

ATC

bromocriptine; oral

+∞

9.5

F02.39

ICD-10 Finland

Dementia in Parkinson's disease without information on additional symptoms

+∞

9.5

N06DA03

ATC

rivastigmine; oral, transdermal

8.1

9.2

AEA00

NOMESCO Finland

Replacement of impulse generator of stimulation device in the nervous system

49.7

7.9

N04BX01

ATC

tolcapone; oral

87.4

7.5

WYA30

NOMESCO Finland

Preparations for expected poor cooperation

8.0

7.2

N04BC09

ATC

rotigotine; transdermal

75.2

6.5

307

Kela drug reimbursment

Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease

5.4

6.4

N04AA01

ATC

trihexyphenidyl; oral

+∞

6.3

N04C02

ATC

+∞

6.3

A06AD11

ATC

lactulose; oral

3.6

6.3

140

XA800

NOMESCO Finland

Neuropsychological investigation

13.9

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

503

0.48

2.86

3.9

5.5

5.85

6.16

mmol/l

1.15

433

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

486

0.49

2.64

4.9

6.8

38.88

42.16

mmol/mol

2.10

436

(3052851) Hemolysis interference index of Serum or Plasma

4.13

2.30

4.0

3.8

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

473

0.52

2.27

18.0

16.4

80.94

69.18

ml/min/173m2

3.98

376

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

537

0.54

2.16

6.9

10.8

14.84

22.97

u/l

5.42

502

(3022145) Colonoscopy Study observation

0.00

2.15

0.0

1.2

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

298

0.47

2.09

3.2

3.0

28.94

56.33

u/l

3.51

263

(3020564) Creatinine [Moles/volume] in Serum or Plasma

532

0.55

2.02

20.7

20.5

67.77

85.96

umol/l

8.17

532

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.00

1.96

0.0

1.8

—

403.04

—

(3009508) Creatinine [Moles/volume] in Urine

173

0.41

1.84

1.6

2.9

8.01

7.10

mmol/l

—

141

(40761536) Microorganisms panel - Urine sediment

0.00

1.76

0.0

3.9

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

0.00

1.75

0.0

3.5

—

1.22

—

(3013707) Erythrocyte sedimentation rate by Westergren method

401

0.56

1.73

3.4

4.1

12.82

15.60

mm/h

0.57

349

(3044889) 12 lead EKG panel

380

0.55

1.73

3.4

4.5

—

(3045414) Leukocytes [Presence] in Urine

3.14

1.61

3.3

1.8

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

156

0.47

1.42

2.3

3.0

23.00

32.41

u/l

—

147

(3042936) Bacteria identified in Isolate by Culture

2.07

1.42

2.1

1.6

—

(40761511) CBC panel - Blood by Automated count

526

0.62

1.40

13.5

16.7

—

(3041096) Erythrocytes [Presence] in Urine by Automated

145

0.44

1.35

4.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

511

0.63

1.29

20.5

17.4

28.20

26.92

mg/l

0.10

421

(3013512) EKG study

181

0.50

1.27

5.1

4.8

—

(40760892) CBC W Ordered Manual Differential panel - Blood

110

0.42

1.23

4.6

5.0

—

(3003694) ABO and Rh group [Type] in Blood

113

0.41

1.23

1.0

1.3

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

0.00

1.19

0.0

5.9

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.15

1.19

3.1

1.4

—

(3002385) Erythrocyte distribution width [Ratio]

410

0.66

1.06

23.3

20.6

13.89

14.05

0.27

396

(3025941) Bacteria identified in Stool by Culture

0.00

0.97

0.0

1.3

—

(3035350) Ketones [Presence] in Urine by Test strip

266

0.64

0.93

4.4

—

0.00

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.07

0.89

1.0

1.5

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.00

0.80

0.0

1.3

—

(3007930) Methemoglobin/Hemoglobin.total in Blood

0.00

0.80

0.0

3.4

—

0.86

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

211

0.65

0.74

4.0

4.7

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

302

0.72

0.65

5.8

8.4

3.52

4.46

e9/l

2.36

257

(3009542) Hematocrit [Volume Fraction] of Blood

425

0.74

0.64

22.0

18.5

36.25

38.10

0.38

249

(3033658) Prothrombin time (PT) actual/Normal

132

1.46

0.63

3.5

98.94

81.71

1.95

127

(3020961) Endomysium IgA Ab [Titer] in Serum

0.00

0.61

0.0

1.0

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

0.00

0.61

0.0

1.2

—

(3037121) Protein [Mass/volume] in Urine

0.00

0.61

0.0

3.5

—

0.21

—

(3019225) pH of Specimen

1.56

0.60

2.4

3.6

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.60

0.0

1.0

—

(3015235) Bicarbonate [Moles/volume] in Capillary blood

0.00

0.60

0.0

2.5

—

26.07

—

(3037467) Urinalysis macro (dipstick) panel - Urine

381

0.75

0.59

7.6

4.6

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

0.00

0.59

0.0

1.1

—

203.97

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

134

0.63

0.57

1.1

1.5

1.24

1.26

mmol/l

—

105

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

243

0.72

0.56

3.0

3.7

—

(3015736) pH of Urine

209

0.71

0.53

3.1

4.4

—

(40768804) Tissue Pathology biopsy report

195

0.72

0.48

1.5

2.5

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.65

0.44

1.2

1.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.54

0.42

1.0

1.3

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.41

0.0

1.9

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.1

—

(3047181) Lactate [Moles/volume] in Blood

0.00

0.41

0.0

4.4

—

1.39

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.1

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.41

0.0

1.0

—

57.07

—

(3012501) Base excess in Blood by calculation

0.00

0.41

0.0

1.9

—

2.51

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.41

0.0

1.9

—

4.79

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.41

0.0

1.3

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.41

0.0

1.9

—

8.16

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

0.00

0.41

0.0

1.8

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.41

0.0

1.5

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.40

0.0

1.3

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.40

0.0

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.40

0.0

1.3

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.40

0.0

1.3

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.39

0.0

1.2

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

0.00

0.39

0.0

1.9

—

0.36

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.39

0.0

1.3

—

(3044640) Blood type and Crossmatch panel - Blood

182

1.28

0.38

2.4

2.0

—

(3000850) Epithelial cells [#/volume] in Urine

142

0.74

0.34

1.9

2.7

8.17

5.23

e6/l

—

126

(3022948) Iron [Moles/volume] in Serum or Plasma

0.70

0.33

1.0

2.6

12.07

12.56

umol/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

244

1.22

0.31

2.6

2.1

73.88

89.71

pmol/l

1.39

118

(3022217) INR in Platelet poor plasma by Coagulation assay

109

0.71

0.31

4.5

28.0

—

1.28

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

132

1.26

0.28

2.0

1.9

—

(3026493) Urate [Moles/volume] in Serum or Plasma

137

0.78

0.26

1.5

3.2

351.45

5417.08

umol/l

0.79

110

(3021589) Normoblasts [#/volume] in Blood

231

0.83

0.26

5.7

10.1

0.00

e9/l

0.71

189

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.30

0.23

5.3

9.9

—

(3000492) Spirometry study

1.23

0.22

1.4

1.5

—

(36304419) Bacteria [Presence] in Urine

155

1.20

0.22

2.7

3.5

—

(4010399)

1.20

0.22

1.8

1.2

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.21

0.0

9.0

—

(21494755) Public health laboratory ask at order entry panel

0.00

0.21

0.0

1.5

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

1.13

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.21

0.0

1.3

—

89.47

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.8

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

2.1

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.1

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.2

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

0.28

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3018572) Chloride [Moles/volume] in Blood

0.00

0.21

0.0

4.3

—

105.58

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3039000) Anion gap in Blood

0.00

0.21

0.0

4.3

—

11.50

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.21

0.0

1.5

—

1.49

—

(3003327) Ova and parasites identified in Stool by Light microscopy

0.00

0.21

0.0

1.2

—

(1616796) Gas panel - Central venous blood

0.00

0.21

0.0

1.5

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

0.00

0.21

0.0

1.4

—

(40768800) Prostate Pathology biopsy report

0.00

0.21

0.0

1.2

—

(40767503) Oxygen content in Capillary blood by calculation

0.00

0.20

0.0

1.9

—

15.30

—

(3021960) Folate [Moles/volume] in Serum or Plasma

148

1.18

0.18

1.8

18.90

21.03

nmol/l

0.28

116

(3007853) Bacteria identified in Skin by Aerobe culture

1.20

0.18

1.6

1.8

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

207

1.15

0.17

2.8

2.1

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.12

0.16

3.5

1.6

—

(3030467) Casts [#/volume] in Urine by Automated count

169

1.16

0.16

2.7

3.6

0.43

0.59

e6/l

0.28

133

(3023368) Bacteria identified in Blood by Culture

191

0.86

0.15

5.1

4.1

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

0.79

0.15

1.0

2.7

22.50

23.04

—

(3026008) Bacteria identified in Urine by Culture

203

1.11

0.11

7.5

3.4

—

(42870588) Differential panel, method unspecified - Blood

164

1.12

0.11

3.2

4.4

—

(3002256) Pathology report gross observation

1.12

0.08

1.3

1.5

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.09

0.08

3.5

1.7

—

(40758558) Short blood count panel - Blood

128

1.11

0.07

6.1

7.4

—

(3018418) pH of Serum or Plasma

182

0.92

0.06

2.3

4.2

—

7.40

—

(3031040) Bacteria [#/volume] in Urine by Automated count

383

0.94

0.06

8.9

5.3

—

741.82

—

(3018095) Leukocytes [#/volume] in Urine

210

0.94

0.04

4.9

4.6

784.29

78.91

e6/l

0.91

159

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

210

1.06

0.04

3.2

3.9

—

(3006315) Basophils [#/volume] in Blood

249

0.95

0.03

5.0

4.9

0.04

e9/l

0.10

210

(3001604) Monocytes [#/volume] in Blood

248

0.96

0.02

5.0

4.9

0.49

0.61

e9/l

1.89

208

(3002582) Erythrocytes [#/volume] in Urine

185

1.03

0.00

3.7

3.8

51.31

370.88

e6/l

0.46

147

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

109

1.01

0.00

3.0

1.7

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.7

—

270.14

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.0

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.3

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

3.9

—

155.43

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

5.9

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

2.1

—

15.43

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

5.9

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

3.4

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.0

3.3

—

2.36

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.1

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.0

—

(3014271) Vancomycin [Susceptibility]

0.00

0.0

2.8

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

1.0

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.1

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

2.2

—

18.06

—

(44806118)

0.00

0.0

1.4

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

0.0

2.3

—

5.78

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay

0.00

0.0

1.2

—

(44790049)

0.00

0.0

1.4

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.9

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

0.0

1.2

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

10.68

—

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.0

—

(3000494) Fungus identified in Specimen by Culture

0.92

0.00

1.2

1.5

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

86.17

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

0.0

2.3

—

66.50

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.4

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

130

1.00

0.00

3.5

4.2

—

(44790047)

0.00

0.0

1.4

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

0.0

14.4

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

2.7

—

31.33

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

0.0

1.5

—

8.17

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.0

1.0

—

(40761535) Cells panel - Urine sediment

0.92

0.00

1.8

3.8

—

(3000012) Reticulocyte production index

0.00

0.0

1.8

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

0.0

1.4

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

5.4

—

(44790048)

0.00

0.0

1.4

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.3

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.2

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.0

1.6

—

129.00

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

3.8

—

25.20

—

(4146454)

0.00

0.0

2.2

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

2.8

—

4.25

—

(3024980) IgG subclass 4 [Mass/volume] in Serum

0.00

0.0

1.4

—

0.49

—

(3012441) Differential panel - Pleural fluid

0.00

0.0

1.7

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: PDMED_PERGOLIDE – Use of pergolide

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Use of pergolide

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Case counts by code for Use of pergolide (PDMED_PERGOLIDE)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints