Benign neoplasm: Pineal gland

CD2_BENIGN_PINEAL_EXALLC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data
1. Apply sex-specific rule None	-
2. Check conditions None
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D35.4& Hospital discharge: ICD-9 — 2274 Hospital discharge: ICD-8 — 2263 Cause of death: ICD-10 — D35.4& Cause of death: ICD-9 — 2274 Cause of death: ICD-8 — 2263 2 out of 7 registries used, show all original rules.	-
4. Check minimum number of events None	-
5. Include endpoints None	-
6. Filter based on genotype QC (FinnGen only) None	-

Control definitions (FinnGen only)

Control exclude: C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D35
Name in latin: Neoplasma benignum corporis pinealis

NAME	CD2_BENIGN_PINEAL_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D354
HD_ICD_9	2274
HD_ICD_8	2263
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D354
COD_ICD_9	2274
COD_ICD_8	2263
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Pineal gland based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Pineal gland

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	82	61	21
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	36.89	35.46	41.04

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
76: Matched controls
761

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D35.4

ICD-10 Finland

Benign neoplasm: Pineal gland

+∞

101.4

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

10.0

9.9

G93.0

ICD-10 Finland

Cerebral cysts

56.8

8.9

AAB00

NOMESCO Finland

Extirpation of intracranial lesion

100.8

8.6

R51.80

ICD-10 Finland

Headache

5.3

8.3

AA1BG

NOMESCO Finland

Standard MRI examination of brain with high intensity magnet

7.5

6.6

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3032080) INR in Blood by Coagulation assay

156

2.59

3.94

3.5

5.6

1.0

1.1

inr

—

(3035637) Corticotropin [Mass/volume] in Plasma

12.79

3.82

1.0

1.8

—

(3013707) Erythrocyte sedimentation rate by Westergren method

483

2.88

3.67

3.4

3.6

7.7

8.6

mm/h

0.35

449

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

127

2.53

3.46

1.9

1.8

0.6

1.0

mg/l

0.48

(3014007) Fractional oxyhemoglobin in Arterial blood

6.20

3.43

7.1

8.4

91.7

94.2

—

(3044290) Cell count panel - Cerebral spinal fluid

6.20

3.43

1.0

1.4

—

(3016018) Differential panel - Cerebral spinal fluid

9.12

3.32

1.0

1.4

—

(4035726)

6.26

3.09

1.0

1.3

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

5.77

2.93

1.4

1.1

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

5.35

2.79

7.7

8.1

0.9

0.8

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

5.35

2.79

7.9

8.1

2.1

1.4

—

(3023410) Appearance of Cerebral spinal fluid

6.37

2.75

1.0

1.2

—

(3013512) EKG study

122

2.23

2.48

3.1

2.7

—

(3002256) Pathology report gross observation

2.67

2.33

1.2

1.0

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

633

2.73

2.33

5.3

4.5

1.6

1.7

mu/l

0.46

594

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

136

2.08

2.18

1.7

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

528

2.11

2.01

4.7

4.1

14.6

14.5

pmol/l

0.18

492

(3018405) Lactate [Moles/volume] in Arterial blood

4.76

1.97

11.0

2.5

1.4

1.2

mmol/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

182

1.92

1.97

3.7

2.8

11.5

21.4

ng/l

0.80

(3003396) Base excess in Arterial blood by calculation

2.85

1.93

8.9

5.1

1.5

mmol/l

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

4.36

1.85

1.0

1.1

—

(3019060) Gas panel - Arterial blood

3.15

1.61

10.7

2.6

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

151

1.83

1.58

3.5

1.8

2.4

mmol/l

0.89

132

(3019225) pH of Specimen

2.53

1.51

2.2

4.1

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

630

2.17

1.49

11.8

6.6

92.5

95.5

ml/min/173m2

0.49

492

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

198

1.72

1.45

3.4

2.6

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

446

1.71

1.43

7.4

5.2

73.4

71.7

u/l

0.22

412

(40768804) Tissue Pathology biopsy report

235

1.68

1.41

1.8

1.6

—

(3022621) pH of Urine by Test strip

2.28

1.39

3.1

2.3

—

(3020891) Body temperature

3.06

1.38

10.8

2.4

—

(3023368) Bacteria identified in Blood by Culture

100

1.88

1.36

4.2

2.8

—

(3045414) Leukocytes [Presence] in Urine

2.73

1.23

2.0

1.9

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.99

1.21

1.7

2.2

15.8

15.3

umol/l

0.10

(3009542) Hematocrit [Volume Fraction] of Blood

672

2.04

1.18

11.4

9.9

39.0

40.5

0.59

563

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.59

1.17

1.2

1.4

—

(3044889) 12 lead EKG panel

399

1.57

1.14

2.8

2.7

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.98

1.04

8.1

5.4

1.1

1.0

mmol/l

—

(3044640) Blood type and Crossmatch panel - Blood

187

1.57

1.03

1.9

1.8

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.09

1.03

1.7

1.5

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.82

0.96

3.8

2.0

29.4

26.9

u/l

—

(3000991) Gas panel - Venous blood

2.32

0.95

2.3

6.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

202

1.50

0.88

1.4

1.6

109.6

94.2

pmol/l

0.51

107

(3024354) Oxygen [Partial pressure] in Venous blood

1.94

0.83

1.8

3.2

4.0

4.3

kpa

—

(3007164) IgA [Mass/volume] in Serum or Plasma

169

1.50

0.81

1.2

1.3

2.3

2.2

g/l

0.09

107

(3013650) Neutrophils [#/volume] in Blood by Automated count

367

1.43

0.81

6.9

7.6

4.2

3.9

e9/l

0.50

322

(3021601) Nitrite [Presence] in Urine by Test strip

328

1.43

0.81

6.1

4.4

0.0

estimate

—

(3018095) Leukocytes [#/volume] in Urine

224

1.46

0.81

4.2

2.8

151.3

37.3

e6/l

0.48

144

(3017044) Thyrotropin receptor Ab [Units/volume] in Serum

0.00

0.80

0.0

2.6

—

5.2

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

2.25

0.77

1.8

3.1

134.0

133.9

g/l

—

(4034850)

2.25

0.77

4.4

13.5

—

(3012544) pH of Venous blood

1.87

0.75

1.9

3.6

—

(40761535) Cells panel - Urine sediment

1.77

0.72

2.6

2.5

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.50

0.72

1.8

1.6

—

(3009261) Glucose [Presence] in Urine by Test strip

334

1.39

0.71

5.2

3.3

0.0

estimate

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.61

0.67

2.3

1.6

—

(3048689) Calprotectin [Mass/mass] in Stool

114

1.50

0.65

3.3

2.1

134.6

79.5

ug/g

0.35

(3019832) Treponema pallidum Ab [Presence] in Serum

194

0.66

0.65

1.4

1.8

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.71

0.62

1.6

1.4

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

1.52

0.61

1.1

1.6

452.1

463.7

pmol/l

0.04

(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.61

0.0

1.1

—

1.5

—

(42870588) Differential panel, method unspecified - Blood

188

1.39

0.61

6.9

6.1

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.60

0.0

1.1

—

2.8

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.60

0.0

1.0

—

(36304419) Bacteria [Presence] in Urine

161

1.41

0.60

3.5

2.4

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

134

1.44

0.59

1.6

1.7

2.2

2.7

mg/l

0.74

114

(40761536) Microorganisms panel - Urine sediment

1.53

0.59

9.3

3.2

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

630

1.46

0.58

3.7

3.3

5.6

5.7

mmol/l

0.46

584

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

304

1.33

0.56

3.7

3.8

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

109

1.46

0.56

1.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.51

0.55

7.1

5.3

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

1.54

0.53

2.0

3.5

5.8

5.9

kpa

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

214

1.31

0.48

2.3

—

(3018418) pH of Serum or Plasma

149

1.36

0.47

3.8

2.4

7.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.44

0.46

1.6

1.3

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

1.44

0.46

2.3

2.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.40

0.42

2.9

2.3

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.1

—

0.0

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.41

0.0

1.1

—

98.9

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.1

—

0.9

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.1

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.41

0.0

1.3

—

(4268621)

0.00

0.41

0.0

2.1

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.43

0.40

3.6

1.8

3.7

6.1

umol/l

—

(3042936) Bacteria identified in Isolate by Culture

1.41

0.40

1.4

2.2

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

1.39

0.40

1.3

2.1

27.0

30.1

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.39

0.0

1.1

—

(3028707) Methadone [Presence] in Urine by Screen method

1.41

0.39

1.6

1.8

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

194

1.26

0.34

2.1

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.36

0.34

2.8

2.0

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

129

1.30

0.33

1.8

2.1

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.41

0.32

1.0

1.1

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.38

0.32

1.9

1.4

—

(36660697) Celiac disease serology panel - Serum

1.38

0.32

1.1

—

(3029937) Albumin [Presence] in Urine by Test strip

178

1.24

0.30

7.0

3.4

0.0

estimate

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

122

1.28

0.29

1.1

1.6

—

(40758558) Short blood count panel - Blood

151

1.25

0.28

7.9

5.9

—

(3016879) Cocaine [Presence] in Urine

1.23

0.28

1.5

1.6

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

659

0.81

0.27

4.1

3.3

1.6

1.5

mmol/l

0.71

625

(40768797) Stomach Pathology biopsy report

1.28

0.27

1.1

1.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

219

1.20

0.26

1.2

1.8

—

(3026008) Bacteria identified in Urine by Culture

182

1.21

0.24

4.4

2.4

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.30

0.23

1.6

1.4

—

(3035350) Ketones [Presence] in Urine by Test strip

330

1.16

0.22

5.3

3.1

0.0

estimate

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.20

0.22

1.2

1.5

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.21

0.0

1.5

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

194

1.18

0.21

1.9

1.3

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.21

0.0

1.0

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.21

0.0

1.2

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.21

0.0

1.0

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.20

0.0

1.0

—

0.0

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.20

0.0

1.0

—

10.7

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.20

0.0

1.0

—

39.7

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.20

0.0

1.0

—

0.0

—

(3017732) Neutrophils [#/volume] in Blood

1.22

0.20

4.5

3.0

4.2

e9/l

—

(3003694) ABO and Rh group [Type] in Blood

246

0.86

0.20

1.6

1.7

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

157

1.19

0.19

5.1

2.9

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.23

0.19

1.6

—

(1761868) Lipid panel - Serum or Plasma

265

0.87

0.18

2.6

2.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.20

0.17

1.1

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

1.18

0.17

1.6

—

(3027008) Opiates [Presence] in Urine

1.18

0.17

1.6

1.5

—

(3028300) Cannabinoids [Presence] in Urine

1.18

0.17

1.6

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.16

0.17

1.0

1.6

—

(3027944) Amphetamines [Presence] in Urine

1.16

0.17

1.8

1.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

188

1.16

0.17

4.5

2.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

258

1.13

0.15

5.5

3.1

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

190

1.14

0.14

1.0

1.3

0.6

1.3

u/ml

—

(3015736) pH of Urine

271

0.89

0.14

5.0

2.8

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

105

0.84

0.14

2.0

1.9

—

(21494755) Public health laboratory ask at order entry panel

108

0.81

0.14

1.3

—

(3037467) Urinalysis macro (dipstick) panel - Urine

469

1.11

0.13

5.9

3.9

—

(3002385) Erythrocyte distribution width [Ratio]

601

1.13

0.13

15.6

11.2

13.3

13.4

0.29

594

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

126

0.85

0.12

1.6

1.5

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.17

0.10

3.4

2.6

—

(3011288) Drugs identified in Urine by Screen method

1.09

0.10

1.4

2.1

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

664

0.90

0.09

4.1

3.4

4.9

4.8

mmol/l

0.79

630

(40760892) CBC W Ordered Manual Differential panel - Blood

166

1.11

0.08

4.8

4.7

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

1.05

0.08

1.4

1.5

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

1.05

0.08

1.4

1.5

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

1.05

0.08

1.4

1.5

—

(3000494) Fungus identified in Specimen by Culture

1.03

0.08

1.4

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

1.07

0.08

1.5

1.6

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.86

0.07

1.3

1.4

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

121

0.90

0.06

1.3

1.2

2.2

6.2

u/ml

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

218

1.08

0.06

2.4

1.7

—

(3012516) Albumin [Mass/volume] in Urine

131

1.08

0.04

8.1

3.0

110.4

74.1

mg/l

—

(3031040) Bacteria [#/volume] in Urine by Automated count

441

1.05

0.03

6.9

3.7

—

44.9

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

272

1.04

0.02

1.5

2.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

604

1.04

0.00

4.2

3.9

—

(3020682) Albumin/Creatinine [Ratio] in Urine

137

1.03

0.00

9.5

3.9

34.1

9.6

mg/mmol

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

667

1.02

0.00

4.2

3.6

2.9

mmol/l

0.03

631

(3021589) Normoblasts [#/volume] in Blood

294

0.98

0.00

13.9

6.7

0.0

e9/l

0.00

242

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.98

0.00

1.7

1.5

—

(3022145) Colonoscopy Study observation

0.89

0.00

1.6

1.4

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

5.8

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

0.00

0.0

7.6

—

10.4

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

2.7

—

4.0

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.4

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.1

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.0

—

13.1

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

0.0

1.4

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.3

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

1.0

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.0

1.2

—

(4062490)

0.00

0.0

1.6

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.0

2.8

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3025149) Bordetella pertussis IgA Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

2.7

—

105.7

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.84

0.00

1.6

1.4

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.4

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.1

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.90

0.00

1.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

2.7

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.93

0.00

1.2

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.6

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.89

0.00

1.5

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.6

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

0.0

2.6

—

56.0

—

(3005033) Fetal Nuchal fold Thickness US

1.02

0.00

1.5

1.4

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(4024509)

0.00

0.0

1.4

—

(3022756) Ceruloplasmin [Mass/volume] in Serum or Plasma

0.00

0.0

1.1

—

282.3

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

0.0

1.2

—

(3034426) Prothrombin time (PT)

0.00

0.0

1.2

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_PINEAL_EXALLC – Benign neoplasm: Pineal gland

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Benign neoplasm: Pineal gland

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints