No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
73 |
4. Check minimum number of eventsNone |
73 |
5. Include endpointsNone |
73 |
6. Filter based on genotype QC (FinnGen only) |
72 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Cyclic neutropenia
based on the number of shared cases.
Similar with more cases:
- Agranulocytosis
- Other diseases of blood and blood-forming organs, wide
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 72 | 48 | 24 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 52.14 | 52.41 | 51.59 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 73
- Matched controls
- 730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D70.81
ICD-10 Finland
Neutropenia congenital
+∞
104.9
73
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
165.8
30.4
30
*
L03AA02
ATC
filgrastim; parenteral
46.8
24.2
29
10
R50.9
ICD-10 Finland
Fever, unspecified
7.6
15.8
31
65
A49.9
ICD-10 Finland
Bacterial infection, unspecified
12.2
12.8
24
28
L03AA13
ATC
pegfilgrastim; parenteral
15.0
12.6
21
19
XW000
NOMESCO Finland
Bone marrow biopsy
19.7
11.5
17
11
H02AB02
ATC
dexamethasone; systemic
6.3
11.2
24
53
1501
Kela drug reimbursment
Palbociclib
127.6
10.7
11
*
L01XE33
ATC
[U] palbociclib
+∞
10.7
10
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
63.8
9.9
11
*
394
Kela drug reimbursment
Palbociclib
114.2
9.7
10
*
JN4BD
NOMESCO Finland
Extensive body CT
6.2
9.4
19
39
115
Kela drug reimbursment
Breast cancer
5.9
9.3
20
44
A41.9
ICD-10 Finland
Sepsis, unspecified
28.3
9.2
12
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.1
8.9
18
37
A03FA01
ATC
metoclopramide; systemic, rectal
4.4
8.8
33
115
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
+∞
8.5
8
*
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
25.5
8.3
11
5
192
Kela drug reimbursment
Fulvestrant
88.7
7.6
8
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
15.9
7.2
11
8
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.7
7.0
44
212
L02BA03
ATC
fulvestrant; parenteral
44.2
6.9
8
*
A04AA01
ATC
ondansetron; systemic, rectal
7.3
6.8
16
27
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
63
341
7.19
9.60
34.5
10.8
2.38
4.00
e9/l
8.84
58
298
14
17
9.89
7.22
10.8
3.1
33.07
17.59
u/ml
1.03
14
17
22
81
3.46
5.08
2.6
2.5
9.25
3.29
e6/l
0.57
11
48
28
129
2.90
4.37
2.1
2.0
0.76
1.07
mg/l
0.42
23
98
22
90
3.07
4.22
2.5
1.8
—
—
—
0
0
16
54
3.51
4.15
11.5
4.7
26.28
5.00
ug/l
0.43
11
43
21
87
2.98
3.92
2.7
2.4
2.80
0.95
e6/l
—
10
52
17
64
3.16
3.71
2.5
1.5
—
—
—
0
0
17
65
3.11
3.61
2.2
1.5
—
—
—
0
0
12
32
4.28
3.59
2.4
1.6
—
—
—
0
0
13
42
3.55
3.57
1.5
1.5
—
—
—
0
0
11
28
4.43
3.46
1.4
1.1
—
—
—
0
0
17
77
2.57
2.62
2.5
1.8
16.12
13.46
umol/l
1.00
17
71
34
210
2.16
2.60
2.8
3.2
14.52
20.09
ng/l
0.93
25
126
32
193
2.17
2.60
2.8
2.8
—
—
—
0
0
10
32
3.45
2.55
6.8
3.0
18.40
49.40
u/ml
—
10
32
27
154
2.20
2.50
2.9
2.7
0.52
0.44
e6/l
0.09
20
116
8
22
3.95
2.44
2.3
3.2
24.61
25.23
mmol/l
—
8
22
7
17
4.43
2.42
1.6
5.4
25.14
24.76
mmol/l
—
7
17
5
9
5.87
2.25
1.8
2.9
—
—
—
0
0
7
19
3.96
2.21
1.4
1.2
—
—
—
0
0
6
14
4.57
2.20
1.8
1.9
—
—
—
0
0
8
26
3.32
2.08
2.4
6.3
25.11
26.04
mmol/l
—
8
26
63
529
2.39
1.81
41.8
14.5
15.43
14.49
%
0.71
63
524
5
13
4.04
1.74
1.2
1.2
—
—
—
0
0
32
217
1.85
1.73
1.9
1.8
95.34
96.90
pmol/l
0.06
22
103
35
245
1.82
1.70
10.8
9.4
1.00
1.24
inr
—
8
75
6
20
3.17
1.61
1.0
1.3
—
—
—
0
0
65
570
2.28
1.48
31.9
11.0
89.31
86.33
ml/min/173m2
0.52
56
455
5
17
3.08
1.38
1.4
3.7
0.00
0.00
g/l
—
5
17
5
17
3.08
1.38
1.4
3.7
0.00
0.00
g/l
—
5
17
5
17
3.08
1.38
1.4
3.7
0.00
0.00
g/l
—
5
17
21
133
1.81
1.37
3.0
2.0
—
—
—
0
0
37
283
1.62
1.20
3.4
2.3
—
—
—
0
0
5
20
2.61
1.17
1.4
3.3
—
—
—
0
0
26
184
1.64
1.13
2.2
2.4
50.88
54.79
u/l
0.18
26
169
67
613
2.13
1.06
35.7
11.9
19.89
20.31
mg/l
0.05
60
457
5
22
2.36
1.05
1.2
1.2
—
—
—
0
0
5
22
2.36
1.05
1.2
1.2
—
—
—
0
0
10
55
1.95
0.97
1.8
2.0
328.00
385.53
nmol/l
—
10
49
6
28
2.24
0.94
2.2
1.9
13.72
14.65
nmol/l
—
6
28
9
149
0.55
0.92
1.4
1.6
1.13
1.37
mmol/l
—
9
127
0
26
0.00
0.80
0.0
1.6
—
2.71
—
0
17
0
27
0.00
0.79
0.0
1.3
—
—
—
0
0
17
233
0.65
0.78
3.5
3.3
—
—
—
0
0
8
53
1.57
0.61
4.1
7.3
103.50
103.60
mmol/l
—
8
53
8
54
1.54
0.59
2.9
3.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
15
122
1.29
0.30
1.8
1.4
—
—
—
0
0
6
82
0.71
0.25
2.3
2.1
—
—
—
0
0
5
38
1.34
0.24
1.2
1.3
—
—
—
0
0
5
41
1.24
0.22
4.4
5.1
1.21
1.23
mmol/l
—
5
35
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
13.40
—
0
10
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
6
75
0.78
0.16
1.5
2.0
—
—
—
0
0
47
449
1.13
0.14
3.2
3.3
—
—
—
0
0
16
142
1.16
0.14
1.8
1.5
—
—
—
0
0
11
101
1.10
0.04
2.7
1.7
608.18
459.80
pmol/l
0.33
11
82
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
11.00
—
0
5
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: D3_CYCLIC_NEUTROPENIA – Cyclic neutropenia
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).