This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Huntington disease
G6_HUNTINGTON
obsolete_Huntington's disease: ['A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea.', 'A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)']
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
42 |
4. Check minimum number of eventsNone |
42 |
5. Include endpointsNone |
42 |
6. Filter based on genotype QC (FinnGen only) |
42 |
Control definitions (FinnGen only)
- Control exclude
- G6_NEUATR
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G10-G13
- Name in latin
- Morbus Huntington
Similar endpoints
↥List of similar endpoints to
Huntington disease
based on the number of shared cases.
Similar with more cases:
- Systemic atrophies primarily affecting the central nervous system
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 576 | 300 | 267 |
| Only index persons | 422 | 230 | 192 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 57.44 | 57.08 | 57.37 |
| Only index persons | 56.47 | 56.80 | 56.07 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 42 | 22 | 20 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 50.08 | 53.04 | 46.84 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(36660697) Celiac disease serology panel - Serum
10
27
4.55
3.60
1.1
1.1
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
5
7
7.90
2.62
2.2
2.7
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
15
73
2.64
2.13
1.3
1.3
g/l
2.5
2.9
—
9
45
(1616796) Gas panel - Central venous blood
5
10
5.50
2.13
1.8
3.5
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
6
17
3.93
1.91
1.0
1.4
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
24
158
2.21
1.67
8.5
7.2
mmol/l
1.2
1.2
1.61
19
128
(42870588) Differential panel, method unspecified - Blood
19
116
2.16
1.57
4.0
5.5
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
6
21
3.15
1.57
5.2
6.2
mmol/l
26.5
25.4
—
6
21
(3000492) Spirometry study
0
38
0.00
1.43
0.0
1.4
—
—
—
0
0
(3026782) Osmolality of Urine
11
55
2.35
1.43
6.5
3.2
mosm/kgh2o
417.4
529.7
1.68
11
50
(3027945) Reticulocytes/100 erythrocytes in Blood
8
39
2.29
1.23
1.6
2.1
%
1.8
1.9
—
8
30
(3023520) Reticulocytes [#/volume] in Blood
6
26
2.52
1.23
2.8
2.5
e9/l
60.6
69.9
—
6
18
(3019225) pH of Specimen
6
26
2.52
1.23
3.2
4.3
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
19
125
1.95
1.23
2.1
1.9
pmol/l
108.2
104.1
0.12
12
56
(3022145) Colonoscopy Study observation
7
33
2.34
1.12
1.4
1.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
9
47
2.16
1.11
1.0
1.2
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
5
22
2.44
1.06
2.2
1.4
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
22
160
1.79
1.00
4.8
5.5
%
0.7
0.7
0.16
22
149
(3006504) Eosinophils/100 leukocytes in Blood
22
160
1.79
1.00
5.0
5.7
%
2.4
2.8
0.37
22
151
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
10
56
2.03
0.98
1.6
1.7
—
—
—
0
0
(3019069) Monocytes/100 leukocytes in Blood
22
161
1.77
0.97
5.1
6.1
%
8.3
8.4
0.05
22
153
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
8
42
2.11
0.95
2.4
3.0
%
27.9
25.1
—
8
32
(3037467) Urinalysis macro (dipstick) panel - Urine
28
222
1.78
0.92
4.5
4.6
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
15
101
1.75
0.85
5.5
3.1
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
18
128
1.71
0.85
6.3
7.9
inr
1.2
1.1
—
8
41
(3022948) Iron [Moles/volume] in Serum or Plasma
9
52
1.93
0.83
2.3
2.7
umol/l
14.5
14.7
—
9
45
(3019060) Gas panel - Arterial blood
0
26
0.00
0.81
0.0
5.3
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
22
168
1.65
0.78
5.0
5.7
%
28.0
28.8
0.15
22
157
(3029937) Albumin [Presence] in Urine by Test strip
13
86
1.74
0.78
5.3
4.0
estimate
0.0
0.0
—
7
30
(3018418) pH of Serum or Plasma
14
95
1.71
0.77
3.1
4.5
ph
7.4
7.4
—
7
22
(3024561) Albumin [Mass/volume] in Serum or Plasma
19
143
1.60
0.70
5.8
4.5
g/l
36.7
36.2
0.18
19
135
(3018010) Neutrophils/100 leukocytes in Blood
21
162
1.59
0.70
4.8
5.7
%
58.3
57.0
0.22
21
154
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
30
340
0.59
0.69
5.2
4.6
mmol/l
2.9
2.8
0.04
25
314
(3005719) IgG [Mass/volume] in Serum or Plasma
5
29
1.82
0.66
1.8
1.4
g/l
10.5
10.7
—
5
24
(40761536) Microorganisms panel - Urine sediment
5
30
1.75
0.63
7.4
4.0
—
—
—
0
0
(3013512) EKG study
12
84
1.60
0.57
1.9
3.9
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
6
38
1.67
0.57
9.3
3.6
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
12
86
1.55
0.52
3.5
3.0
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
34
365
0.64
0.47
9.2
10.2
u/l
22.2
27.1
2.19
34
356
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
0
15
0.00
0.42
0.0
1.2
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
10
133
0.67
0.42
2.0
1.9
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
0
16
0.00
0.42
0.0
2.1
—
0.3
—
0
11
(3008898) HLA-B27 [Presence]
0
16
0.00
0.42
0.0
1.1
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
11
81
1.49
0.41
4.5
5.4
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
37
342
1.69
0.40
13.7
14.6
mg/l
16.0
21.3
0.63
31
264
(3009542) Hematocrit [Volume Fraction] of Blood
30
328
0.70
0.37
12.2
14.1
%
38.8
41.2
0.68
23
244
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
15
122
1.36
0.33
5.5
3.7
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
12
95
1.37
0.30
3.3
4.9
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
18
154
1.30
0.27
6.3
4.9
estimate
0.0
0.0
—
7
31
(3003694) ABO and Rh group [Type] in Blood
7
92
0.71
0.26
1.3
1.4
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
18
156
1.27
0.24
5.1
3.6
estimate
0.0
0.0
—
6
29
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
5
39
1.32
0.24
1.4
1.7
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
18
157
1.26
0.23
5.0
3.5
estimate
0.0
0.0
—
7
32
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
5
42
1.22
0.22
1.4
1.6
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
0
11
0.00
0.21
0.0
2.5
—
150.9
—
0
11
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
0
11
0.00
0.21
0.0
1.0
—
193.6
—
0
6
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
0
11
0.00
0.21
0.0
2.4
—
90.4
—
0
11
(3048929) Epstein Barr virus Ab [Presence] in Serum
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.2
—
2.2
—
0
5
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
6
48
1.29
0.21
8.0
7.1
mmol/l
1.0
1.0
—
6
42
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3044889) 12 lead EKG panel
22
242
0.81
0.20
3.0
3.5
—
—
—
0
0
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
35
362
0.80
0.19
14.2
12.8
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
5
65
0.74
0.18
1.2
1.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
6
74
0.78
0.17
1.5
2.3
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
9
108
0.79
0.15
2.4
2.5
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
10
85
1.23
0.14
6.4
3.4
mg/l
19.8
104.6
—
10
48
(1761868) Lipid panel - Serum or Plasma
13
117
1.16
0.09
3.0
2.7
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
37
361
1.21
0.09
16.5
16.3
umol/l
71.5
77.9
1.23
37
361
(46235355) HIV 1 and 2 tests - Meaningful Use set
8
77
1.05
0.08
1.3
1.7
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
9
87
1.04
0.07
2.4
2.9
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
23
241
0.90
0.06
2.6
3.0
u/l
31.3
49.6
1.40
23
234
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
22
229
0.92
0.04
3.2
2.9
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
32
314
1.08
0.01
16.0
13.4
ml/min/173m2
87.2
84.3
0.40
27
244
(3041096) Erythrocytes [Presence] in Urine by Automated
10
96
1.05
0.00
7.6
3.3
—
—
—
0
0
(3015736) pH of Urine
13
128
1.02
0.00
2.8
3.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
16
158
1.02
0.00
3.6
4.6
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
8
88
0.89
0.00
3.6
4.4
ug/l
1.2
2.2
—
8
81
(40758558) Short blood count panel - Blood
8
88
0.89
0.00
5.8
8.0
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3029634) Reagin Ab [Titer] in Serum by VDRL
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
8
0.00
0.00
0.0
6.0
—
140.3
—
0
8
(3024928) Oxygen saturation in Venous blood
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3043409) Potassium [Moles/volume] in Arterial blood
0
9
0.00
0.00
0.0
4.8
—
4.0
—
0
9
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
6
67
0.88
0.00
1.0
1.3
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3023420) DNA double strand Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
4.7
—
3.3
—
0
6
(3049717) Cytology report of Urine Cyto stain
0
9
0.00
0.00
0.0
3.3
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026179) Normetanephrine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
0.4
—
0
6
(3039162) Centromere protein B Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
0
5
0.00
0.00
0.0
2.0
—
77.8
—
0
5
(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
2.5
—
8.2
—
0
6
(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
2.9
—
19.8
—
0
8
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
60.7
—
0
6
(3016650) Hepatitis A virus Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
0
7
0.00
0.00
0.0
2.6
—
3.0
—
0
7
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(4306422)
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
35
346
1.07
0.00
18.5
16.4
mmol/l
138.9
139.8
0.91
35
338
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
0
8
0.00
0.00
0.0
3.5
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
7
68
1.04
0.00
2.0
3.3
—
—
—
0
0
(3023103) Potassium [Moles/volume] in Serum or Plasma
35
347
1.05
0.00
18.1
16.4
mmol/l
4.0
4.0
0.23
35
338
(3008037) Lactate [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
2.5
—
1.3
—
0
6
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay
0
7
0.00
0.00
0.0
1.3
—
71.1
—
0
7
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(4268621)
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_HUNTINGTON and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HUNTINGTON | 3.689 [2.58, 5.28] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.177 |
During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 233 females with G6_HUNTINGTON died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HUNTINGTON | 4.281 [2.63, 6.98] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.019 |
During the follow-up period (1.1.1998 — 31.12.2019), 125 out of 211 males with G6_HUNTINGTON died.
Mortality risk
Mortality risk for people of age
years, who have G6_HUNTINGTON.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.368% | 0.785% |
| 5 | 2.324% | 4.79% |
| 10 | 5.626% | 12.173% |
| 15 | 10.095% | 22.838% |
| 20 | 16.027% | 35.987% |
Relationships between endpoints
↥Index endpoint: G6_HUNTINGTON – Huntington disease
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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