Cyst of iris, ciliary body and anterior chamber

H7_CYSTIRIS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H21.3 Hospital discharge: ICD-9 — 3646 Cause of death: ICD-10 — H21.3 Cause of death: ICD-9 — 3646 2 out of 7 registries used, show all original rules.	57
4. Check minimum number of events None	57
5. Include endpoints None	57
6. Filter based on genotype QC (FinnGen only)	57

Control definitions (FinnGen only)

Control exclude: H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H21
Name in latin: Cysta iridis, corporis ciliaris sive camerae anterioris

NAME	H7_CYSTIRIS
CONTROL_EXCLUDE	H7_SCLERACORNEA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H213
HD_ICD_9	3646
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H213
COD_ICD_9	3646
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Cyst of iris, ciliary body and anterior chamber based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	405	229	175
Only index persons	363	217	146
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	45.34	47.89	41.99
Only index persons	47.84	48.18	47.34

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	57	39	18
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	49.02	52.14	42.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.79

1.40

1.2

1.1

—

(3037467) Urinalysis macro (dipstick) panel - Urine

326

1.92

1.35

3.8

3.9

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.08

1.33

2.5

2.7

0.8

0.7

e6/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

181

1.68

1.06

2.0

89.4

101.8

pmol/l

0.49

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

361

1.78

1.03

4.8

4.1

15.3

14.9

pmol/l

0.46

330

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.90

1.02

2.5

2.7

0.2

4.9

e6/l

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.95

0.95

1.4

1.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

218

1.56

0.84

3.1

4.3

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.81

0.0

1.2

—

(3044640) Blood type and Crossmatch panel - Blood

145

1.58

0.81

2.2

—

(3015736) pH of Urine

192

1.54

0.79

2.0

3.2

—

(3000494) Fungus identified in Specimen by Culture

1.75

0.78

1.4

1.3

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

2.28

0.78

2.4

3.8

26.5

24.3

mmol/l

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

102

1.64

0.77

2.2

3.0

—

(3025941) Bacteria identified in Stool by Culture

2.18

0.76

1.2

—

(3022313) Gas panel - Capillary blood

2.18

0.76

2.4

3.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

440

1.81

0.75

19.3

14.2

40.2

0.01

333

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.09

0.74

1.4

—

(1002224) Polysomnography panel

2.01

0.72

1.0

1.1

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.01

0.72

3.6

6.8

25.4

mmol/l

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

104

1.60

0.72

2.5

2.2

—

(3044889) 12 lead EKG panel

316

1.49

0.66

3.6

3.7

—

(36660697) Celiac disease serology panel - Serum

1.62

0.63

1.1

1.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

162

1.47

0.62

2.4

2.9

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.61

0.0

1.1

—

(3013512) EKG study

132

0.62

0.61

3.4

3.6

—

(3037121) Protein [Mass/volume] in Urine

0.00

0.60

0.0

3.5

—

0.1

—

(3016879) Cocaine [Presence] in Urine

0.00

0.60

0.0

1.2

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.59

0.0

1.1

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.59

0.0

1.2

—

(3027008) Opiates [Presence] in Urine

0.00

0.59

0.0

1.2

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

455

1.55

0.52

4.2

5.6

5.8

mmol/l

1.42

419

(40768804) Tissue Pathology biopsy report

205

1.39

0.52

1.8

1.9

—

(3002385) Erythrocyte distribution width [Ratio]

408

1.49

0.52

19.7

17.1

13.8

13.7

0.32

403

(3012516) Albumin [Mass/volume] in Urine

112

1.46

0.51

1.9

3.4

29.4

18.9

mg/l

—

(3026493) Urate [Moles/volume] in Serum or Plasma

115

1.41

0.45

1.5

3.0

366.8

6221.8

umol/l

—

(36304419) Bacteria [Presence] in Urine

125

1.39

0.43

2.6

2.7

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.42

0.0

2.3

—

(3049717) Cytology report of Urine Cyto stain

0.00

0.42

0.0

2.3

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.42

0.0

1.4

—

(3006184) Hemoglobin [Mass/volume] in Capillary blood

0.00

0.41

0.0

2.2

—

127.5

—

(3023368) Bacteria identified in Blood by Culture

121

0.70

0.40

2.4

4.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.61

0.39

1.8

1.5

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

0.64

0.36

1.5

1.8

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.39

0.33

2.1

1.3

—

(3022217) INR in Platelet poor plasma by Coagulation assay

1.34

0.32

49.1

23.2

—

1.3

—

(42870588) Differential panel, method unspecified - Blood

169

1.28

0.32

10.6

4.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

117

0.73

0.31

2.4

6.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

122

1.31

0.31

3.0

4.2

4.5

3.3

mg/mmol

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

113

1.32

0.30

1.6

1.7

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.27

0.29

1.6

1.7

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.25

0.28

3.8

2.1

2.3

2.5

g/l

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

477

1.39

0.24

13.0

13.2

18.7

20.0

mg/l

0.16

363

(3026782) Osmolality of Urine

1.32

0.24

1.6

2.5

551.2

557.1

mosm/kgh2o

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

0.00

0.21

0.0

3.5

—

3.1

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

0.00

0.21

0.0

1.5

—

(3009214) Lutropin [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

8.7

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.20

0.0

1.1

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.20

0.0

1.1

—

(3020891) Body temperature

0.00

0.20

0.0

3.1

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.17

0.20

1.3

1.5

—

(3042936) Bacteria identified in Isolate by Culture

1.17

0.18

1.3

2.0

—

(1761868) Lipid panel - Serum or Plasma

188

1.19

0.18

2.6

2.7

—

(3018095) Leukocytes [#/volume] in Urine

159

1.19

0.18

3.0

3.5

2.6

41.0

e6/l

1.39

109

(3022948) Iron [Moles/volume] in Serum or Plasma

1.17

0.17

3.5

2.1

13.2

15.1

umol/l

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

443

1.20

0.14

13.3

12.8

81.9

83.4

ml/min/173m2

0.17

351

(3009508) Creatinine [Moles/volume] in Urine

133

1.17

0.14

1.9

3.0

8.4

mmol/l

—

106

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

105

1.18

0.12

3.2

2.2

2.4

3.0

mg/l

—

(3026008) Bacteria identified in Urine by Culture

144

1.15

0.12

2.4

2.6

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

343

1.13

0.12

2.9

3.4

—

(3031040) Bacteria [#/volume] in Urine by Automated count

303

1.13

0.11

3.9

4.0

—

28.3

—

(3000492) Spirometry study

1.12

0.10

1.0

1.3

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.12

0.09

4.5

5.9

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

186

1.12

0.09

2.3

3.5

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

0.80

0.09

2.8

4.0

1.2

1.1

mmol/l

—

(3002256) Pathology report gross observation

1.04

0.09

1.5

1.2

—

(3006315) Basophils [#/volume] in Blood

256

1.10

0.08

9.1

5.6

0.0

e9/l

0.64

229

(40768797) Stomach Pathology biopsy report

0.79

0.08

1.3

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

0.85

0.07

1.3

3.0

0.8

mmol/l

—

(3000850) Epithelial cells [#/volume] in Urine

1.06

0.07

1.8

2.6

3.3

4.4

e6/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

138

1.12

0.07

1.9

3.4

—

(3003694) ABO and Rh group [Type] in Blood

129

1.11

0.06

1.7

1.5

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

169

1.01

0.00

1.6

3.2

30.5

47.2

ng/l

—

106

(40758558) Short blood count panel - Blood

127

1.03

0.00

10.2

7.9

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

124

0.96

0.00

1.5

1.3

—

0.6

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

296

1.03

0.00

11.4

10.5

3.2

3.8

e9/l

1.45

262

(3001604) Monocytes [#/volume] in Blood

256

1.03

0.00

9.2

5.6

0.6

e9/l

0.03

228

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.0

1.2

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.2

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.2

—

12.7

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.2

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.0

3.3

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.1

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.0

2.0

—

49.5

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.4

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.0

1.7

—

48.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.2

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

12.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.87

0.00

1.2

1.4

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

3.3

—

19.2

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.0

3.0

—

5.3

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.1

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.4

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.1

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

3.8

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.2

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

0.95

0.00

1.3

1.7

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

0.0

1.1

—

(44790049)

0.00

0.0

2.0

—

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

0.96

0.00

1.4

1.6

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

3.3

—

3.9

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

3.3

—

104.3

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.1

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

3.1

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.1

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.6

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

3.3

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

7.2

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.1

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.1

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

2.4

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

0.0

2.1

—

5.6

—

(44806118)

0.00

0.0

2.0

—

(44790047)

0.00

0.0

2.0

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.1

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.2

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.2

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.0

1.4

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

0.96

0.00

1.3

2.2

1.1

1.4

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

2.1

—

31.8

—

(44790048)

0.00

0.0

2.0

—

(3045788) Cell count panel - Pleural fluid

0.00

0.0

1.0

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

1.0

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

17.8

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.4

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

0.0

2.1

—

65.2

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.8

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.1

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

2.6

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

2.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_CYSTIRIS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_CYSTIRIS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: H7_CYSTIRIS – Cyst of iris, ciliary body and anterior chamber

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Cyst of iris, ciliary body and anterior chamber

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints