Malignant otitis externa

H8_EXT_MALIGN

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H60.2 Hospital discharge: ICD-9 — 3801C Cause of death: ICD-10 — H60.2 Cause of death: ICD-9 — 3801C 2 out of 7 registries used, show all original rules.	61
4. Check minimum number of events None	61
5. Include endpoints None	61
6. Filter based on genotype QC (FinnGen only)	61

Control definitions (FinnGen only)

Control exclude: H8_EXTERNAL

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H60
Name in latin: Otitis externa [maligna]

NAME	H8_EXT_MALIGN
CONTROL_EXCLUDE	H8_EXTERNAL
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H602
HD_ICD_9	3801C
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H602
COD_ICD_9	3801C
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Malignant otitis externa based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	540	251	283
Only index persons	480	228	252
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	54.45	50.70	57.43
Only index persons	53.03	48.66	56.98

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	61	31	30
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	53.84	47.01	60.89

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
55: Matched controls
551

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H60.2

ICD-10 Finland

Malignant otitis externa

+∞

76.1

H60.9

ICD-10 Finland

Otitis externa, unspecified

25.1

15.0

H60.8

ICD-10 Finland

Other otitis externa

67.2

13.6

H60.3

ICD-10 Finland

Other infective otitis externa

166.4

13.0

H66.0

ICD-10 Finland

Acute suppurative otitis media

14.5

9.6

DC1AD

NOMESCO Finland

Temporalbone CT

92.0

7.6

H66.9

ICD-10 Finland

Otitis media, unspecified

12.4

6.9

UDC00

NOMESCO Finland

Ear microscopy

10.2

6.8

H60.0

ICD-10 Finland

Abscess of external ear

+∞

6.4

H70.1

ICD-10 Finland

Chronic mastoiditis

+∞

6.4

A46

ICD-10 Finland

Erysipelas

6.8

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007853) Bacteria identified in Skin by Aerobe culture

8.93

15.11

3.9

2.0

—

(3000494) Fungus identified in Specimen by Culture

5.13

7.54

3.5

1.5

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

4.30

4.98

4.9

1.3

—

(3006315) Basophils [#/volume] in Blood

216

3.23

4.65

8.3

6.0

0.0

e9/l

1.09

195

(3019198) Lymphocytes [#/volume] in Blood

222

3.10

4.33

8.3

5.9

2.0

1.8

e9/l

0.61

203

(3042936) Bacteria identified in Isolate by Culture

3.51

4.31

4.9

1.8

—

(3013115) Eosinophils [#/volume] in Blood

223

3.08

4.27

8.6

5.9

0.2

e9/l

0.52

203

(3027273) Bicarbonate [Moles/volume] in Venous blood

5.00

4.27

5.2

2.7

23.4

24.9

mmol/l

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

3.33

4.25

10.2

2.7

440.9

170.6

ng/l

0.30

(3001604) Monocytes [#/volume] in Blood

215

3.04

4.23

8.4

5.9

0.6

e9/l

0.15

193

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

3.45

4.20

4.5

1.8

—

(42870588) Differential panel, method unspecified - Blood

127

3.02

4.18

8.8

5.3

—

(3019060) Gas panel - Arterial blood

4.79

4.06

10.2

4.2

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

9.68

3.88

1.7

1.6

—

(3020682) Albumin/Creatinine [Ratio] in Urine

140

2.85

3.82

4.0

3.4

18.9

4.5

mg/mmol

0.69

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

3.65

3.82

5.0

1.4

—

(3012516) Albumin [Mass/volume] in Urine

134

2.82

3.72

3.3

2.9

61.2

38.3

mg/l

0.21

(3009508) Creatinine [Moles/volume] in Urine

145

2.72

3.52

3.2

2.8

6.6

8.3

mmol/l

1.33

126

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

4.94

2.90

25.3

6.5

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

4.21

2.80

5.0

2.5

117.6

133.0

g/l

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

6.51

2.76

3.7

1.6

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

3.31

2.74

6.2

2.3

5.8

5.7

kpa

0.22

(3022948) Iron [Moles/volume] in Serum or Plasma

2.83

2.59

6.0

1.7

11.3

14.1

umol/l

1.13

(3021960) Folate [Moles/volume] in Serum or Plasma

100

2.49

2.58

1.8

1.6

15.8

20.3

nmol/l

0.70

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

4.79

2.55

4.7

1.9

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

5.41

2.46

1.8

1.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

159

2.25

2.40

2.8

1.9

86.0

89.8

pmol/l

0.18

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

427

2.84

2.35

6.0

4.6

1.9

mu/l

0.05

390

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.34

2.25

2.1

1.8

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

4.02

2.22

2.7

1.7

—

(3020891) Body temperature

4.02

2.22

10.0

2.9

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

429

2.79

2.18

8.7

5.1

43.5

40.1

mmol/mol

1.12

402

(3023368) Bacteria identified in Blood by Culture

116

2.24

2.13

9.8

4.1

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

2.58

2.08

13.5

3.5

1.1

1.0

mmol/l

0.29

(3000991) Gas panel - Venous blood

2.93

1.96

22.1

5.2

—

(3024354) Oxygen [Partial pressure] in Venous blood

3.13

1.94

7.4

2.4

4.5

4.6

kpa

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

450

2.74

1.92

5.4

4.2

6.3

5.9

mmol/l

1.27

414

(3015377) Calcium [Moles/volume] in Serum or Plasma

147

2.04

1.85

3.5

3.3

2.3

2.4

mmol/l

0.45

130

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

3.38

1.70

6.3

2.5

1.3

1.1

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

3.53

1.55

1.4

1.2

—

(3000492) Spirometry study

2.60

1.53

1.1

1.6

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

479

2.50

1.52

5.8

4.5

2.6

2.8

mmol/l

0.51

443

(3044889) 12 lead EKG panel

316

1.91

1.52

5.9

3.5

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

183

1.85

1.50

3.8

3.9

57.8

26.4

ng/l

0.53

125

(40758558) Short blood count panel - Blood

115

1.95

1.47

7.5

7.7

—

(3021589) Normoblasts [#/volume] in Blood

185

1.82

1.43

16.0

9.4

0.0

e9/l

0.50

155

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

3.11

1.38

1.2

1.5

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.22

1.37

2.3

1.7

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.55

1.35

23.6

5.2

1.2

1.4

mmol/l

—

(3031040) Bacteria [#/volume] in Urine by Automated count

303

1.80

1.33

7.7

4.1

—

24.3

—

(3018418) pH of Serum or Plasma

119

1.87

1.32

13.1

4.0

7.4

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.93

1.31

29.0

6.3

25.2

24.3

mmol/l

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

1.93

1.25

2.1

1.6

0.4

1.3

mg/l

—

(3026008) Bacteria identified in Urine by Culture

121

1.83

1.25

5.2

2.9

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.45

1.22

29.7

7.0

91.5

94.7

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

450

2.05

1.21

4.6

3.6

1.6

1.3

mmol/l

1.72

417

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.86

1.18

3.0

2.3

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.96

1.18

2.2

1.8

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

478

2.13

1.17

36.1

13.5

26.9

23.6

mg/l

0.22

367

(40760892) CBC W Ordered Manual Differential panel - Blood

1.84

1.14

4.3

6.1

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

2.10

1.14

8.0

1.7

2.3

2.5

g/l

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

467

2.03

1.12

5.1

4.0

1.3

1.5

mmol/l

1.39

433

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

467

2.03

1.12

5.3

4.0

4.5

4.7

mmol/l

0.52

435

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.84

1.10

1.9

1.8

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

303

1.67

1.09

4.8

3.2

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

109

1.78

1.08

7.7

3.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

217

1.64

1.06

8.6

3.7

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.38

1.05

4.0

2.2

—

(3007164) IgA [Mass/volume] in Serum or Plasma

102

1.77

1.03

1.5

1.4

2.4

2.2

g/l

—

(3033658) Prothrombin time (PT) actual/Normal

111

1.74

1.02

8.3

3.4

96.4

93.6

0.21

111

(3044640) Blood type and Crossmatch panel - Blood

139

1.65

0.95

3.5

2.3

—

(3015736) pH of Urine

175

1.61

0.95

6.8

3.1

—

(40761511) CBC panel - Blood by Automated count

500

2.01

0.95

31.4

12.6

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.26

0.94

29.7

6.5

0.6

0.7

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.26

0.94

29.7

6.6

2.0

1.6

—

(40761535) Cells panel - Urine sediment

1.99

0.92

4.9

3.7

—

(36660697) Celiac disease serology panel - Serum

1.94

0.90

1.1

1.2

—

(3023520) Reticulocytes [#/volume] in Blood

2.11

0.89

1.8

1.7

71.1

77.1

e9/l

—

(3009542) Hematocrit [Volume Fraction] of Blood

417

1.71

0.89

38.3

13.2

40.0

40.3

0.14

325

(3032080) INR in Blood by Coagulation assay

196

1.57

0.89

12.0

6.1

1.0

1.1

inr

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

441

1.74

0.85

22.4

12.4

80.3

85.4

ml/min/173m2

0.64

367

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.91

0.81

1.5

1.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.91

0.81

1.5

1.9

—

(40768804) Tissue Pathology biopsy report

200

1.52

0.80

2.5

2.0

—

(3002256) Pathology report gross observation

1.71

0.77

1.1

1.2

—

(4010399)

1.95

0.77

1.6

1.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.09

0.74

1.2

2.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

0.50

0.74

1.6

1.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

320

1.50

0.74

5.9

3.8

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

157

1.51

0.72

5.6

3.2

37.0

28.3

u/l

0.46

148

(4035726)

1.71

0.69

1.1

1.3

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

160

1.48

0.66

5.2

2.9

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.65

0.63

2.1

1.9

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

191

1.42

0.59

11.5

4.1

33.8

35.8

g/l

1.14

185

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.59

0.0

1.7

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.59

0.58

8.4

—

(3003338) MCHC [Mass/volume]

403

1.44

0.55

46.9

17.5

333.2

332.8

g/l

0.15

403

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.60

0.55

12.5

3.4

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

507

1.57

0.44

34.5

15.5

91.3

74.0

umol/l

0.78

507

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.42

0.0

1.7

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.41

0.0

1.5

—

(3019225) pH of Specimen

1.47

0.40

1.8

6.0

—

(40761536) Microorganisms panel - Urine sediment

1.42

0.39

2.2

3.0

—

(1761868) Lipid panel - Serum or Plasma

176

0.73

0.39

3.3

2.7

—

(36304419) Bacteria [Presence] in Urine

128

1.34

0.37

5.8

2.7

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

1.38

0.35

1.5

1.7

498.4

483.8

pmol/l

0.04

(3041096) Erythrocytes [Presence] in Urine by Automated

140

0.74

0.32

3.4

2.7

—

(40768797) Stomach Pathology biopsy report

1.36

0.30

1.6

1.2

—

(3013512) EKG study

116

1.27

0.25

4.4

3.6

—

(3021601) Nitrite [Presence] in Urine by Test strip

232

1.21

0.24

8.8

4.3

0.0

estimate

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.21

0.0

1.2

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.4

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

2.5

—

17.8

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.2

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.20

0.0

1.8

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.20

0.0

1.1

—

(3000570) Elastase.pancreatic [Mass/mass] in Stool

0.00

0.20

0.0

1.6

—

234.4

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.20

0.0

1.7

—

(3003694) ABO and Rh group [Type] in Blood

133

1.17

0.13

1.4

1.5

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

192

1.14

0.13

6.3

3.4

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

126

1.14

0.10

5.9

4.7

18.0

20.7

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.04

0.07

1.6

1.5

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

7.7

—

182.6

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

2.4

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

2.4

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

2.4

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.0

1.9

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

2.4

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.0

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.3

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3022145) Colonoscopy Study observation

0.90

0.00

1.4

1.3

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.6

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.6

—

92.2

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

1.8

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.2

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.00

0.00

3.2

2.9

56.0

27.6

u/l

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

10.8

—

0.6

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.0

1.0

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

2.2

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.96

0.00

2.2

2.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.0

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.3

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

2.2

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

1.3

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint H8_EXT_MALIGN and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
H8_EXT_MALIGN	1.384 [0.95, 2.01]	0.086
Birth year	0.989 [0.98, 1.0]	0.022

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 238 males with H8_EXT_MALIGN died.

Mortality risk

Mortality risk for people of age

years, who have H8_EXT_MALIGN.

N-year risk	Females	Males
1	No data	0.279%
5	No data	1.591%
10	No data	4.158%
15	No data	8.048%
20	No data	13.472%

Relationships between endpoints

↥

Index endpoint: H8_EXT_MALIGN – Malignant otitis externa

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Malignant otitis externa

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints