connective tissue disease: A disorder characterized by abnormalities in one or more of the elements of the connective tissues, typically associated with genetic defects.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
67 |
4. Check minimum number of eventsNone |
67 |
5. Include endpointsNone |
67 |
6. Filter based on genotype QC (FinnGen only) |
65 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L94
- Name in latin
- Calcinosis cutis
Similar endpoints
↥List of similar endpoints to
Calcinosis cutis
based on the number of shared cases.
Similar with more cases:
- Other localized connective tissue disorders
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 288 | 172 | 115 |
| Only index persons | 267 | 159 | 108 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 64.69 | 68.70 | 58.79 |
| Only index persons | 64.73 | 68.91 | 58.58 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 65 | 38 | 27 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 64.64 | 66.73 | 61.70 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 67
- Matched controls
- 670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L94.2
ICD-10 Finland
Calcinosis cutis
+∞
96.2
67
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
710.8
39.3
35
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
20.9
32.2
30
25
A46
ICD-10 Finland
Erysipelas
16.7
31.1
37
46
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
+∞
28.1
25
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
147.0
27.0
27
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
15.9
26.0
28
29
TK800
NOMESCO Finland
Hemodialysis
182.7
24.4
24
*
A11CC03
ATC
alfacalcidol; systemic
91.4
22.7
24
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
91.4
22.7
24
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
55.4
21.7
25
7
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
149.6
20.9
21
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
+∞
20.9
19
*
C03CA01
ATC
furosemide; systemic
10.7
20.1
49
136
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
+∞
19.7
18
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
+∞
19.7
18
*
ZXD05
NOMESCO Finland
Urgent procedure
9.3
19.0
44
114
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
21.9
18.7
28
21
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
30.2
18.1
24
12
M04AA01
ATC
allopurinol; systemic
9.5
18.0
29
50
A12AA04
ATC
calcium carbonate; oral
120.6
17.5
18
*
V03AE02
ATC
sevelamer; oral
+∞
17.4
16
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
223.4
17.4
17
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
8.5
17.2
33
69
137
Kela drug reimbursment
Uraemia requiring dialysis
206.2
16.2
16
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
103.1
15.3
16
*
N18.8
ICD-10 Finland
Other chronic renal failure
103.1
15.3
16
*
S97
ICPC
Chronic ulcer skin
16.6
15.2
25
23
NHQ40
NOMESCO Finland
Amputation of toe
189.7
15.1
15
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.6
14.7
24
41
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
21.2
14.3
21
14
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
21.2
14.3
21
14
TPX10
NOMESCO Finland
Implantation of vascular injection port
23.1
14.1
20
12
H05BX01
ATC
cinacalcet; oral
+∞
14.0
13
*
B03XA02
ATC
darbepoetin alfa; parenteral
51.5
13.9
16
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
7.4
13.8
27
56
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
30.0
13.8
18
8
I50.9
ICD-10 Finland
Heart failure, unspecified
7.4
13.5
26
53
Z49.2
ICD-10 Finland
Other dialysis
+∞
12.9
12
*
L04AA06
ATC
mycophenolic acid; systemic
47.4
12.8
15
*
TPH04
NOMESCO Finland
Cathetrisation of vein
6.3
12.8
33
89
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.4
12.6
23
44
127
Kela drug reimbursment
Transplant complication
79.2
12.1
13
*
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
143.7
11.8
12
*
V03AE03
ATC
lanthanum carbonate; oral
+∞
11.8
11
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
+∞
11.8
11
*
205
Kela drug reimbursment
Chronic hypertension
5.7
11.5
38
126
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
52.9
11.4
13
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
7.3
11.2
20
37
NG4AA
NOMESCO Finland
Lower leg X-ray examination
20.5
11.0
16
10
B05DB
ATC
Hypertonic solutions
129.4
10.8
11
*
Z94.0
ICD-10 Finland
Kidney transplant status
129.4
10.8
11
*
B05DA
ATC
Isotonic solutions
129.4
10.8
11
*
321
Kela drug reimbursment
Paricalcitol and cinacalcet
+∞
10.7
10
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
+∞
10.7
10
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.5
10.7
31
91
WX402
NOMESCO Finland
General anaesthesia
5.8
10.5
26
66
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
24.7
10.3
14
7
V03AE01
ATC
polystyrene sulfonate; oral
64.7
10.0
11
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
35.9
9.8
12
*
WX213
NOMESCO Finland
Lower leg blockade
115.7
9.7
10
*
N18.0
ICD-10 Finland
End-stage renal disease
115.7
9.7
10
*
TK820
NOMESCO Finland
Peritoneal dialysis
+∞
9.6
9
*
J01FF01
ATC
clindamycin; systemic
4.9
9.5
36
129
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
12.2
9.5
17
18
B01AA03
ATC
warfarin; systemic
5.5
9.4
24
62
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
43.1
9.3
11
*
ZZA00
NOMESCO Finland
Split skin graft
43.1
9.3
11
*
J01CF05
ATC
flucloxacillin; systemic
12.7
9.1
16
16
R4190
NOMESCO Finland
Nutritional therapy
14.5
9.1
15
13
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
6.3
9.0
18
37
J01MA12
ATC
levofloxacin; systemic
5.0
8.7
25
71
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
102.4
8.6
9
*
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
102.4
8.6
9
*
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
102.4
8.6
9
*
L04AD02
ATC
tacrolimus; systemic
102.4
8.6
9
*
H02AB04
ATC
methylprednisolone; systemic
5.4
8.6
21
52
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
+∞
8.5
8
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
+∞
8.5
8
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.9
8.5
48
229
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
38.5
8.3
10
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
4.9
8.2
24
69
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
11.0
8.1
15
17
C02AC05
ATC
moxonidine; oral
11.0
8.1
15
17
S18
ICPC
Laceration/cut
4.8
8.1
49
243
XF400
NOMESCO Finland
ECG with 12 standard connections
4.9
8.0
23
65
ZX120
NOMESCO Finland
Intravenous
7.6
8.0
19
33
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
14.3
8.0
13
11
L28
ICPC
Limited function/disability (L)
4.7
7.9
25
76
K65.0
ICD-10 Finland
Acute peritonitis
51.2
7.9
9
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
5.5
7.8
18
42
N02AA05
ATC
oxycodone; systemic
4.5
7.7
26
83
ZXE00
NOMESCO Finland
One hour or less
4.2
7.7
42
191
ZXE10
NOMESCO Finland
More than one and less than three hours
4.1
7.6
40
177
M13.9
ICD-10 Finland
Arthritis, unspecified
8.8
7.6
16
23
B01AC04
ATC
clopidogrel; oral
4.5
7.4
24
74
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
7.4
7
*
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
+∞
7.4
7
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
+∞
7.4
7
*
PE1AT
NOMESCO Finland
Femoral artery PTA
+∞
7.4
7
*
M10.0
ICD-10 Finland
Idiopathic gout
14.3
7.4
12
10
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.6
7.4
23
69
C07AB07
ATC
bisoprolol; oral
4.5
7.3
49
254
WX408
NOMESCO Finland
General anesthesy, balanced
4.1
7.3
31
117
J01MA02
ATC
ciprofloxacin; systemic
4.0
7.2
40
181
WW200
NOMESCO Finland
Immunization
19.2
7.0
10
6
WX212
NOMESCO Finland
Femoral plexus blockade
19.2
7.0
10
6
TPH07
NOMESCO Finland
Cathetrisation of artery
6.6
7.0
18
35
L04AA01
ATC
[U] ciclosporin
44.7
6.9
8
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
25.6
6.9
9
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
11.9
6.9
12
12
C08CA01
ATC
amlodipine; oral
3.9
6.8
41
194
A10AC01
ATC
insulin (human); parenteral
7.4
6.8
16
27
WX320
NOMESCO Finland
Spinalanesthesy
3.9
6.7
29
110
XF600
NOMESCO Finland
Bloodpressure measurement
7.7
6.6
15
24
M10.9
ICD-10 Finland
Gout, unspecified
7.7
6.6
15
24
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
6.5
6.6
17
33
ZXD10
NOMESCO Finland
Scheduled procedure
3.7
6.6
40
190
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
76.9
6.5
7
*
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
76.9
6.5
7
*
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
76.9
6.5
7
*
QDA10
NOMESCO Finland
Incision of skin of lower limb
76.9
6.5
7
*
3AC01, ,
NOMESCO Finland
76.9
6.5
7
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
76.9
6.5
7
*
B01AB10
ATC
tinzaparin; parenteral
5.1
6.5
16
39
NGQ20
NOMESCO Finland
Amputation of lower leg
+∞
6.3
6
*
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
+∞
6.3
6
*
TK810
NOMESCO Finland
Hemofiltration
+∞
6.3
6
*
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
+∞
6.3
6
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
+∞
6.3
6
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.9
6.3
16
40
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.7
6.3
29
114
R50.9
ICD-10 Finland
Fever, unspecified
4.4
6.3
19
55
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
4.8
6.1
16
41
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
10.7
6.1
11
12
L04AX01
ATC
azathioprine; systemic
10.7
6.1
11
12
TQW11
NOMESCO Finland
Vacuum treatment of wound
12.8
6.0
10
9
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
47
64
22.25
38.16
32.8
3.5
1.31
1.07
mmol/l
3.68
47
59
34
43
15.02
27.91
30.5
4.7
2.16
2.21
mmol/l
0.02
34
30
32
53
10.64
20.83
2.7
1.5
—
—
—
0
0
28
40
11.31
20.42
43.1
7.3
1.28
1.27
mmol/l
0.03
28
40
32
57
9.83
19.47
2.9
1.5
—
—
—
0
0
37
79
9.23
19.17
2.8
1.6
—
—
—
0
0
29
52
9.07
17.32
9.1
3.7
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
21
12
24.75
15.05
17.8
3.8
0.32
0.63
u/ml
—
12
5
22
35
8.87
14.30
3.6
1.5
—
—
—
0
0
51
191
7.99
14.13
11.4
2.7
—
—
—
0
0
18
8
30.03
13.78
2.4
1.1
—
—
—
0
0
19
14
18.38
12.40
1.8
1.5
0.24
0.23
g/l
0.26
19
14
57
260
8.99
12.11
62.1
6.1
1.20
1.22
mmol/l
0.81
47
219
43
154
6.00
11.97
11.8
2.6
0.36
0.33
e6/l
0.07
37
112
18
15
15.91
11.17
1.9
1.5
1.15
1.16
g/l
0.03
18
15
31
90
5.55
10.82
8.6
2.6
0.53
1.08
e6/l
1.16
20
48
20
25
10.90
10.30
3.7
1.0
—
—
—
0
0
53
253
6.24
9.86
36.9
13.6
1.34
1.25
inr
0.25
16
85
25
65
5.54
9.77
51.0
6.3
99.48
103.34
mmol/l
2.48
25
65
35
122
4.91
9.61
8.5
2.4
—
—
—
0
0
9
0
+∞
9.60
5.9
0.0
5.21
—
mmol/l
—
9
0
13
7
22.56
9.36
2.3
1.1
—
—
—
0
0
28
83
5.08
9.35
9.4
2.9
1.10
3.87
e6/l
1.18
17
42
32
106
4.86
9.32
8.1
3.3
210.16
51.93
ng/l
0.87
32
85
20
31
8.72
9.08
20.9
8.9
23.34
24.45
mmol/l
0.47
20
31
50
243
5.17
8.67
23.1
3.7
31.34
35.58
g/l
6.03
50
228
11
5
25.83
8.32
4.0
2.0
—
—
—
0
0
11
6
21.53
7.90
1.8
1.3
—
—
—
0
0
17
38
5.65
7.69
5.8
3.7
36.63
67.82
ml/min/173m2
—
8
17
10
5
23.08
7.38
1.5
1.2
—
—
—
0
0
15
21
8.86
7.19
42.3
4.1
0.63
0.67
%
0.16
15
21
49
256
4.40
7.19
7.8
2.4
—
—
—
0
0
12
11
12.97
7.13
2.1
1.5
—
—
—
0
0
16
28
7.16
6.67
2.6
1.4
—
—
—
0
0
38
176
3.68
6.45
5.9
3.6
95.23
8.34
mg/mmol
2.07
32
100
14
21
8.12
6.45
45.1
4.1
1.09
1.31
%
0.25
14
21
6
0
+∞
6.34
5.0
0.0
494.00
—
umol/l
—
6
0
10
8
14.40
6.31
1.4
1.0
—
—
—
0
0
10
8
14.40
6.31
1.4
1.0
—
—
—
0
0
15
26
7.11
6.29
43.9
3.8
104.13
130.12
g/l
3.08
15
26
36
164
3.58
6.22
5.4
3.3
14442.97
1277.46
ng/l
1.64
30
136
12
16
8.86
5.94
1.9
1.2
—
—
—
0
0
15
29
6.35
5.83
37.0
7.1
24.07
24.78
mmol/l
0.25
15
29
36
170
3.42
5.78
5.3
2.2
114.78
257.82
u/l
0.74
36
161
8
5
17.87
5.56
1.1
1.4
—
—
—
0
0
8
5
17.87
5.56
1.1
1.4
—
—
—
0
0
8
5
17.87
5.56
1.1
1.4
—
—
—
0
0
8
5
17.87
5.56
1.1
1.4
—
—
—
0
0
8
5
17.87
5.56
1.1
1.4
—
—
—
0
0
8
5
17.87
5.56
1.9
2.6
—
—
—
0
0
12
18
7.86
5.55
2.3
1.7
—
—
—
0
0
10
11
10.44
5.50
1.4
1.1
—
—
—
0
0
5
0
+∞
5.27
4.6
0.0
—
—
—
0
0
8
7
12.74
4.92
2.3
2.0
—
—
—
0
0
12
22
6.40
4.87
17.6
2.7
23.74
24.40
mmol/l
0.37
12
22
7
5
15.38
4.68
2.1
1.2
—
—
—
0
0
7
5
15.38
4.68
1.0
1.4
—
—
—
0
0
8
8
11.14
4.65
2.3
1.9
—
—
—
0
0
13
30
5.12
4.42
2.9
1.4
—
—
—
0
0
9
15
6.74
3.96
1.7
2.3
—
—
—
0
0
6
5
12.98
3.84
1.7
1.2
—
—
—
0
0
8
12
7.40
3.79
1.4
1.1
—
—
—
0
0
8
13
6.82
3.62
2.4
2.3
—
—
—
0
0
31
166
2.61
3.57
13.2
3.4
27.10
33.26
u/l
0.76
31
153
6
6
10.81
3.57
2.3
2.2
—
—
—
0
0
14
53
3.08
3.02
2.2
1.9
313.29
369.94
nmol/l
0.48
14
47
5
6
8.87
2.79
2.0
2.0
—
—
—
0
0
6
10
6.46
2.76
2.8
1.8
—
—
—
0
0
36
226
2.28
2.75
3.1
1.8
98.35
95.78
pmol/l
0.14
23
90
39
268
2.09
2.23
6.7
3.8
0.00
0.00
estimate
—
8
59
39
270
2.06
2.16
10.6
5.0
0.00
0.00
estimate
—
7
57
5
10
5.30
2.11
7.6
2.6
57.80
58.30
%
—
5
10
39
275
2.00
2.00
6.7
3.7
0.00
0.00
estimate
—
7
55
6
16
4.01
1.98
1.8
1.1
—
—
—
0
0
6
16
4.01
1.98
2.3
1.6
—
—
—
0
0
6
16
4.01
1.98
1.8
1.1
—
—
—
0
0
6
17
3.77
1.88
2.3
1.9
—
—
—
0
0
5
12
4.41
1.85
1.0
1.1
—
—
—
0
0
7
23
3.27
1.85
1.9
1.4
—
—
—
0
0
18
103
2.02
1.61
1.4
1.3
13.72
40.96
iu/ml
—
5
35
5
15
3.51
1.55
1.2
1.3
—
—
—
0
0
6
21
3.03
1.54
28.3
2.9
66.72
53.80
%
—
6
21
42
322
1.82
1.51
3.4
2.9
—
—
—
0
0
6
25
2.53
1.27
1.5
4.0
7.17
412.90
u/ml
—
6
20
15
92
1.81
1.08
1.3
1.3
4.44
11.85
u/ml
—
7
38
6
34
1.84
0.60
2.3
2.4
0.15
0.16
e6/l
—
6
34
53
486
1.43
0.51
100.9
15.8
15.90
14.95
%
0.75
53
477
11
136
0.77
0.26
2.5
4.8
32.42
20.66
%
—
6
60
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
72.50
—
0
10
0
12
0.00
0.21
0.0
1.1
—
0.68
—
0
7
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
11
91
1.25
0.19
1.3
1.5
—
—
—
0
0
5
67
0.73
0.18
55.6
8.9
—
—
—
0
0
16
151
1.08
0.04
6.0
4.1
0.00
0.00
estimate
—
6
55
21
214
0.97
0.00
6.0
3.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
16.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
28.74
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
78
0.89
-0.00
2.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_CALCINOSISCUTIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_CALCINOSISCUTIS | 4.812 [1.96, 11.82] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.559 |
During the follow-up period (1.1.1998 — 31.12.2019), 56 out of 132 females with L12_CALCINOSISCUTIS died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have L12_CALCINOSISCUTIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.542% | No data |
| 5 | 3.161% | No data |
| 10 | 7.911% | No data |
| 15 | 14.384% | No data |
| 20 | 23.902% | No data |
Relationships between endpoints
↥Index endpoint: L12_CALCINOSISCUTIS – Calcinosis cutis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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