This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Flatback syndrome
M13_FLATBACK
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
25 |
4. Check minimum number of eventsNone |
25 |
5. Include endpointsNone |
25 |
6. Filter based on genotype QC (FinnGen only) |
25 |
Control definitions (FinnGen only)
- Control exclude
- M13_DORSOPATHY
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M40
- Name in latin
- Syndroma dorsi plani
Similar endpoints
↥List of similar endpoints to
Flatback syndrome
based on the number of shared cases.
Similar with more cases:
- Deforming dorsopathies
- Dorsopathies
- Diseases of the musculoskeletal system and connective tissue
- Factors influencing health status and contact with health services
- Anti-inflammatory and antirheumatic products, non-steroids
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 184 | 99 | 85 |
| Only index persons | 176 | 96 | 80 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | - | 66.47 | 60.97 |
| Only index persons | 63.97 | 66.31 | 61.17 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 25 | 16 | 9 |
| Unadjusted period prevalence (%) | 0.00 | 0.01 | 0.00 |
| Median age at first event (years) | 71.12 | 72.77 | 68.19 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
12
12
18.31
11.36
4.9
5.4
—
—
—
0
0
(3019060) Gas panel - Arterial blood
13
19
13.17
9.45
5.2
4.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
25
141
+∞
5.75
7.4
4.5
—
—
—
0
0
(3015171) Extractable nuclear Ab [Units/volume] in Serum
6
5
15.12
3.98
1.2
1.0
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
13
48
4.56
3.35
2.0
1.5
mmol/l
1.3
1.2
0.28
13
36
(3009542) Hematocrit [Volume Fraction] of Blood
25
180
+∞
3.25
27.8
14.5
%
31.9
39.3
—
9
112
(3019150) Specific gravity of Urine by Refractometry
13
51
4.23
3.04
8.1
3.7
kg/l
1.0
1.0
—
5
5
(36660697) Celiac disease serology panel - Serum
7
14
6.48
2.97
1.3
1.1
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
18
97
4.04
2.64
2.1
1.9
pmol/l
100.1
100.4
—
9
37
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
7
17
5.28
2.57
1.6
1.4
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
7
17
5.28
2.57
1.3
1.5
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
20
120
4.31
2.56
8.6
6.9
mmol/l
1.2
1.2
1.40
20
104
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
5
8
7.45
2.49
1.0
1.0
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
7
18
4.96
2.46
1.4
1.4
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
14
66
3.55
2.40
5.2
5.0
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
7
19
4.69
2.35
1.9
1.8
g/l
0.2
0.2
—
7
19
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
5
9
6.61
2.33
1.0
1.0
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
14
67
3.48
2.32
2.9
3.0
mg/l
15.3
21.3
—
7
44
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
6
15
4.90
2.18
1.7
1.5
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
14
72
3.15
1.99
3.1
3.7
mg/mmol
2.1
3.3
—
7
43
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
8
30
3.43
1.93
1.5
1.7
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
14
75
2.97
1.82
4.1
2.5
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
12
59
2.99
1.81
1.8
1.3
nmol/l
26.3
22.8
0.27
12
47
(3001604) Monocytes [#/volume] in Blood
16
96
2.84
1.75
8.7
5.4
e9/l
0.6
0.6
0.25
16
87
(3006315) Basophils [#/volume] in Blood
16
96
2.84
1.75
8.6
5.4
e9/l
0.1
0.0
1.24
16
87
(3019198) Lymphocytes [#/volume] in Blood
16
97
2.79
1.73
8.7
5.5
e9/l
1.9
1.8
0.17
16
89
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
25
208
+∞
1.72
8.7
6.4
mmol/mol
41.8
40.6
0.33
25
182
(3024561) Albumin [Mass/volume] in Serum or Plasma
17
108
2.78
1.68
10.9
4.7
g/l
32.8
34.9
0.84
17
102
(3042936) Bacteria identified in Isolate by Culture
7
27
3.19
1.66
1.7
2.0
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
15
88
2.76
1.58
10.3
6.2
%
0.9
0.7
0.92
15
82
(3013115) Eosinophils [#/volume] in Blood
16
100
2.66
1.50
9.2
5.4
e9/l
0.2
0.2
0.50
16
93
(3006504) Eosinophils/100 leukocytes in Blood
15
90
2.67
1.49
10.9
6.2
%
2.8
2.6
0.18
15
83
(3019069) Monocytes/100 leukocytes in Blood
15
90
2.67
1.49
11.2
6.5
%
8.8
8.4
0.17
15
84
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
18
120
2.78
1.47
7.4
6.5
umol/l
8.7
10.6
1.04
18
111
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
18
121
2.73
1.46
4.4
2.8
u/l
49.9
56.4
0.11
18
111
(3002030) Lymphocytes/100 leukocytes in Blood
15
91
2.62
1.44
11.1
6.4
%
27.7
26.8
0.12
15
84
(3007853) Bacteria identified in Skin by Aerobe culture
6
24
2.96
1.40
1.2
1.5
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
11
58
2.60
1.39
3.1
2.3
mg/l
1.5
2.8
3.48
11
48
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
0
33
0.00
1.27
0.0
2.5
—
0.7
—
0
24
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
16
204
0.40
1.21
18.7
14.9
ml/min/173m2
78.2
73.0
—
8
166
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
13
82
2.22
1.05
8.3
4.2
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
25
220
+∞
1.05
32.6
15.6
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
25
220
+∞
1.05
6.8
5.2
mmol/l
6.0
6.0
0.05
25
189
(3023103) Potassium [Moles/volume] in Serum or Plasma
25
218
+∞
1.03
35.1
18.0
mmol/l
3.9
4.0
0.89
25
211
(3019550) Sodium [Moles/volume] in Serum or Plasma
25
218
+∞
1.03
35.0
17.8
mmol/l
139.1
139.6
0.40
25
211
(3000494) Fungus identified in Specimen by Culture
6
29
2.40
0.97
1.7
1.2
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
16
118
1.98
0.85
10.4
9.2
e9/l
4.0
4.0
0.02
16
104
(4035726)
0
25
0.00
0.84
0.0
1.6
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
25
224
+∞
0.84
6.3
5.3
mmol/l
2.3
2.5
1.03
25
193
(3020564) Creatinine [Moles/volume] in Serum or Plasma
25
223
+∞
0.83
34.0
18.7
umol/l
68.8
83.1
3.40
25
223
(3011397) Hemoglobin [Presence] in Urine by Test strip
7
42
1.92
0.76
7.3
3.7
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
12
81
1.93
0.75
3.6
3.0
ug/l
89.7
117.0
0.45
12
70
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
13
92
1.86
0.69
3.2
2.3
nmol/l
74.6
79.3
0.30
13
83
(3026493) Urate [Moles/volume] in Serum or Plasma
8
52
1.79
0.68
1.6
3.8
umol/l
294.0
6761.5
—
8
46
(3023368) Bacteria identified in Blood by Culture
10
66
1.86
0.65
6.6
3.8
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
9
61
1.74
0.64
6.3
3.9
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
25
230
+∞
0.63
17.6
10.9
u/l
24.2
23.4
0.11
25
217
(3015736) pH of Urine
11
76
1.80
0.62
7.1
3.8
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
6
39
1.70
0.58
1.5
1.2
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
13
99
1.65
0.49
2.7
2.1
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
0
15
0.00
0.43
0.0
4.3
—
4.5
—
0
15
(3044889) 12 lead EKG panel
19
163
1.69
0.42
6.7
3.8
—
—
—
0
0
(3000991) Gas panel - Venous blood
0
16
0.00
0.42
0.0
3.2
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
0
16
0.00
0.42
0.0
1.2
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
25
234
+∞
0.42
41.4
22.1
e9/l
7.1
6.5
0.92
25
223
(3000963) Hemoglobin [Mass/volume] in Blood
25
234
+∞
0.42
41.4
22.2
g/l
130.8
132.6
0.21
25
229
(3007461) Platelets [#/volume] in Blood
25
234
+∞
0.42
41.6
22.1
e9/l
272.5
241.7
1.73
25
227
(3024731) MCV [Entitic volume]
25
234
+∞
0.42
41.3
22.1
fl
92.0
91.4
0.19
25
229
(3026361) Erythrocytes [#/volume] in Blood
25
234
+∞
0.42
41.3
22.2
e12/l
4.3
4.4
0.31
25
223
(3035941) MCH [Entitic mass]
25
234
+∞
0.42
41.3
22.1
pg
30.8
30.3
0.59
25
229
(3000492) Spirometry study
0
17
0.00
0.42
0.0
1.6
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
5
70
0.64
0.31
2.8
2.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
11
0.00
0.22
0.0
1.5
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
0
11
0.00
0.22
0.0
4.5
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.22
0.0
1.3
—
—
—
0
0
(4034850)
0
10
0.00
0.22
0.0
8.7
—
—
—
0
0
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
0
10
0.00
0.22
0.0
3.0
—
0.8
—
0
10
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
0
10
0.00
0.22
0.0
3.0
—
0.9
—
0
10
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
0
10
0.00
0.22
0.0
1.2
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
11
96
1.26
0.13
4.7
4.5
ng/l
25.5
41.7
—
6
75
(40760892) CBC W Ordered Manual Differential panel - Blood
5
42
1.24
0.11
5.6
4.1
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
5
43
1.20
0.11
1.6
1.4
mg/l
0.6
1.3
—
5
34
(3003694) ABO and Rh group [Type] in Blood
5
60
0.79
0.09
1.2
1.3
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
7
63
1.15
0.09
6.9
5.1
ug/l
0.5
2.1
—
7
54
(40768793) Breast Pathology biopsy report
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(4094501)
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013512) EKG study
7
71
0.98
0.00
1.7
4.6
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
26.1
—
0
7
(3052851) Hemolysis interference index of Serum or Plasma
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
0
7
0.00
0.00
0.0
4.4
—
7.4
—
0
7
(1002224) Polysomnography panel
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
0
7
0.00
0.00
0.0
14.6
—
24.9
—
0
7
(42529406) Shigella sp [Presence] in Stool by Culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
0
5
0.00
0.00
0.0
2.4
—
64.2
—
0
5
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
0
5
0.00
0.00
0.0
2.4
—
4.0
—
0
5
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
8
80
1.00
0.00
2.4
3.0
—
—
—
0
0
(3017044) Thyrotropin receptor Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
5
55
0.89
0.00
1.4
3.1
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
9
90
1.00
0.00
1.7
2.5
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
2.0
—
164.0
—
0
5
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
0
6
0.00
0.00
0.0
7.7
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
4.0
—
3.9
—
0
5
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
3.8
—
21.1
—
0
8
(21494755) Public health laboratory ask at order entry panel
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
0
7
0.00
0.00
0.0
5.1
—
1.3
—
0
7
(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
6.8
—
221.1
—
0
5
(3035285) Chloride [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
4.0
—
106.6
—
0
5
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
4.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_FLATBACK and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have M13_FLATBACK.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: M13_FLATBACK – Flatback syndrome
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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