Benign neoplasm: Respiratory system, unspecified

CD2_BENIGN_RESPIRATORY_NOS_EXALLC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data
1. Apply sex-specific rule None	-
2. Check conditions None
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D14.4& Hospital discharge: ICD-8 — 21299 Cause of death: ICD-10 — D14.4& Cause of death: ICD-8 — 21299 2 out of 7 registries used, show all original rules.	-
4. Check minimum number of events None	-
5. Include endpoints None	-
6. Filter based on genotype QC (FinnGen only) None	-

Control definitions (FinnGen only)

Control exclude: C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D14
Name in latin: Neoplasma benignum organi respiratorii non specificati

NAME	CD2_BENIGN_RESPIRATORY_NOS_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D144
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	21299
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D144
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	21299
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Respiratory system, unspecified based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Respiratory system, unspecified

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	76	36	40
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	52.19	44.26	59.32

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
68: Matched controls
678

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D14.4

ICD-10 Finland

Benign neoplasm: Respiratory system, unspecified

+∞

75.9

21299

ICD-8 Finland

Benign neoplasm of respiratory system, Unspecified site

+∞

10.7

R91

ICD-10 Finland

Abnormal findings on diagnostic imaging of lung

10.4

8.7

DQB10

NOMESCO Finland

Endoscopic excision of lesion of larynx

89.4

7.6

D38.1

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung

76.8

6.5

B97.7

ICD-10 Finland

Papillomavirus as the cause of diseases classified to other chapters

+∞

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768804) Tissue Pathology biopsy report

180

2.90

4.89

2.9

1.5

—

(40758558) Short blood count panel - Blood

136

2.83

4.35

4.5

5.0

—

(3021589) Normoblasts [#/volume] in Blood

250

2.66

4.20

10.6

8.7

0.0

e9/l

0.00

188

(3023368) Bacteria identified in Blood by Culture

142

2.69

3.95

6.7

4.0

—

(3001604) Monocytes [#/volume] in Blood

292

2.60

3.91

5.3

5.0

0.6

e9/l

0.33

247

(3006315) Basophils [#/volume] in Blood

295

2.55

3.79

5.3

5.0

0.0

e9/l

0.41

248

(3013650) Neutrophils [#/volume] in Blood by Automated count

321

2.48

3.50

8.1

6.3

3.9

4.4

e9/l

0.90

274

(4035726)

5.82

3.29

1.4

1.2

—

(3022621) pH of Urine by Test strip

3.82

3.17

2.4

1.9

—

(3000991) Gas panel - Venous blood

3.51

3.07

20.8

4.7

—

(42870588) Differential panel, method unspecified - Blood

179

2.24

2.81

7.2

5.5

—

(3029937) Albumin [Presence] in Urine by Test strip

141

2.28

2.72

3.1

3.9

0.0

estimate

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.84

2.71

1.9

1.7

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

5.81

2.59

1.8

1.2

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

7.54

2.59

2.0

2.4

6.5

4.7

e9/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

6.59

2.41

2.2

2.8

61.0

55.6

—

(3012544) pH of Venous blood

2.70

2.35

4.8

2.8

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.78

2.32

4.7

3.7

—

(3042936) Bacteria identified in Isolate by Culture

2.44

2.28

1.9

2.0

—

(3021788) Differential panel - Synovial fluid

5.85

2.25

1.0

1.2

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

4.55

2.19

2.0

1.3

—

(3021601) Nitrite [Presence] in Urine by Test strip

287

1.93

2.07

3.8

5.1

0.0

estimate

—

(3002582) Erythrocytes [#/volume] in Urine

181

1.97

2.04

3.1

3.0

12.6

474.6

e6/l

0.65

131

(3009261) Glucose [Presence] in Urine by Test strip

290

1.90

1.98

3.1

3.6

0.0

estimate

—

(3025941) Bacteria identified in Stool by Culture

3.40

1.93

2.1

1.5

—

(4010399)

2.57

1.88

1.4

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

4.38

1.85

1.0

1.4

—

(3026008) Bacteria identified in Urine by Culture

154

1.93

1.80

3.2

3.1

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

122

2.00

1.78

1.8

1.7

2.2

1.2

mg/l

0.30

(3035350) Ketones [Presence] in Urine by Test strip

290

1.80

1.71

3.0

3.5

0.0

estimate

—

(3032080) INR in Blood by Coagulation assay

209

1.82

1.68

4.9

7.4

1.0

1.2

inr

2.26

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

201

1.81

1.65

3.4

3.1

—

(3019060) Gas panel - Arterial blood

2.55

1.52

1.6

3.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

398

1.75

1.46

4.0

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

217

1.72

1.44

3.2

3.6

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

550

2.04

1.44

18.6

11.2

80.6

81.2

ml/min/173m2

0.06

430

(3018418) pH of Serum or Plasma

148

1.79

1.42

5.9

2.9

7.4

—

(3003396) Base excess in Arterial blood by calculation

2.15

1.42

16.4

4.5

2.5

1.1

mmol/l

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.03

1.34

1.6

1.7

—

(3045414) Leukocytes [Presence] in Urine

2.62

1.33

1.3

1.5

—

(3002256) Pathology report gross observation

2.20

1.28

1.3

1.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.90

1.26

1.7

—

(3013512) EKG study

162

1.70

1.25

3.1

3.6

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.17

1.19

1.8

1.5

—

(36304419) Bacteria [Presence] in Urine

157

1.67

1.14

3.3

2.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

157

1.67

1.14

2.8

3.3

—

(40761511) CBC panel - Blood by Automated count

629

2.05

1.12

18.0

10.8

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.94

1.12

1.7

—

(40768797) Stomach Pathology biopsy report

1.88

1.11

1.2

1.1

—

(3003327) Ova and parasites identified in Stool by Light microscopy

2.47

1.11

2.0

1.6

—

(3018095) Leukocytes [#/volume] in Urine

212

1.59

1.10

3.8

3.7

44.1

47.7

e6/l

0.04

140

(3022145) Colonoscopy Study observation

1.97

1.09

1.7

1.3

—

(42529406) Shigella sp [Presence] in Stool by Culture

2.36

1.05

1.4

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.36

1.05

1.4

1.2

—

(3044640) Blood type and Crossmatch panel - Blood

144

1.63

1.02

2.7

1.8

—

(3010813) Leukocytes [#/volume] in Blood

657

2.22

0.98

29.3

17.3

6.9

6.7

e9/l

0.19

636

(3026361) Erythrocytes [#/volume] in Blood

657

2.22

0.98

29.2

17.3

4.6

e12/l

0.03

634

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

246

1.52

0.95

5.4

3.4

—

(3007164) IgA [Mass/volume] in Serum or Plasma

114

1.63

0.89

1.4

1.3

1.9

2.4

g/l

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

132

1.59

0.87

1.3

1.2

1.0

1.1

u/ml

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.01

0.86

1.5

1.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.01

0.86

1.3

1.7

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.01

0.86

2.2

1.5

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.95

0.83

2.2

3.7

0.2

e6/l

—

(3000330) Specific gravity of Urine by Test strip

1.95

0.83

1.7

4.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.64

0.83

2.5

1.8

—

(3030467) Casts [#/volume] in Urine by Automated count

169

1.52

0.83

3.3

2.8

0.2

0.4

e6/l

0.33

118

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

593

1.66

0.77

21.7

11.8

28.4

22.9

mg/l

0.66

458

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.77

0.76

1.8

1.5

—

(40761536) Microorganisms panel - Urine sediment

1.93

0.76

4.3

3.8

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.91

0.70

1.0

1.1

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.91

0.70

1.0

1.1

4.0

4.3

g/l

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.91

0.70

3.2

5.7

—

(3016879) Cocaine [Presence] in Urine

0.00

0.61

0.0

1.4

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.61

0.0

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.61

0.0

1.4

—

(3027008) Opiates [Presence] in Urine

0.00

0.61

0.0

1.4

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.61

0.0

1.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.77

0.59

1.3

1.9

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.62

0.59

9.7

3.9

1.3

1.0

mmol/l

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

627

1.58

0.58

23.0

13.5

91.0

77.4

umol/l

0.48

627

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.72

0.58

1.2

1.7

0.2

g/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

237

1.36

0.58

4.1

3.6

19.3

52.8

ng/l

1.60

161

(3044889) 12 lead EKG panel

414

1.35

0.57

4.3

3.8

—

(3000494) Fungus identified in Specimen by Culture

1.57

0.53

1.2

1.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.57

0.53

7.5

6.3

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

111

1.44

0.51

1.6

1.3

37.0

42.8

iu/ml

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

223

1.33

0.49

4.8

2.6

190.4

108.4

ug/l

0.58

207

(3000492) Spirometry study

1.48

0.44

1.3

1.4

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.65

0.44

2.8

2.0

—

(40760892) CBC W Ordered Manual Differential panel - Blood

133

1.36

0.43

3.5

3.9

—

(3019150) Specific gravity of Urine by Refractometry

133

1.36

0.43

3.6

3.3

1.0

kg/l

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.55

0.42

4.6

2.4

133.4

133.6

g/l

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.41

0.0

1.3

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.40

0.0

1.1

—

(3037121) Protein [Mass/volume] in Urine

0.00

0.40

0.0

1.7

—

0.2

—

(3015736) pH of Urine

229

1.28

0.40

2.9

3.3

—

(4094501)

0.00

0.39

0.0

1.1

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

1.42

0.39

2.8

2.3

—

(1761868) Lipid panel - Serum or Plasma

229

0.77

0.37

2.2

3.0

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.41

0.32

1.1

1.9

494.0

336.3

nmol/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.32

0.29

2.3

2.0

—

(3009542) Hematocrit [Volume Fraction] of Blood

539

1.23

0.27

22.4

13.0

39.8

40.7

0.29

395

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

550

1.23

0.26

4.4

1.8

1.9

mu/l

0.19

496

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.21

0.26

1.3

1.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.38

0.24

1.0

1.2

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.31

0.23

4.6

2.2

0.8

mmol/l

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.27

0.23

2.2

3.0

0.2

4.1

e6/l

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.1

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

1.5

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.4

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.2

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.2

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.2

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.26

0.20

1.4

1.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.25

0.18

1.9

1.6

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

371

1.11

0.11

3.9

3.1

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

193

1.12

0.11

5.2

3.6

21.0

24.7

0.54

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

106

1.16

0.10

2.6

1.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.10

0.09

2.3

1.7

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.10

0.08

1.7

1.6

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

119

1.11

0.06

5.1

3.2

496.4

100.7

ng/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

228

1.08

0.06

2.5

1.9

90.5

95.0

pmol/l

0.25

125

(3003694) ABO and Rh group [Type] in Blood

141

1.08

0.04

1.3

1.4

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(4268621)

0.00

0.0

2.0

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.3

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.4

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

2.0

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

109.3

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

1.4

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

226.8

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.00

0.00

1.6

1.4

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(4306422)

0.00

0.0

1.0

—

(3017569) Oxygen content in Arterial blood

0.00

0.0

1.6

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

140

1.00

0.00

3.6

3.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

2.5

—

106.6

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.97

0.00

1.7

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

2.5

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

217.2

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(4027681)

0.00

0.0

1.0

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

2.5

—

4.0

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

2.8

—

(3016038) Potassium [Moles/volume] in Urine

0.00

0.0

1.0

—

23.2

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

1.6

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.2

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

1.5

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.0

—

94.3

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

1953.8

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.0

2.1

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.2

—

(3022689) Creatine [Moles/volume] in Urine

0.00

0.0

1.6

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.4

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

0.0

4.5

—

18.5

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_RESPIRATORY_NOS_EXALLC – Benign neoplasm: Respiratory system, unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Benign neoplasm: Respiratory system, unspecified

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints