Disorders of muscle tone of newborn

P16_DISORD_MUSCLE_TONE_NEWBO

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P94 Cause of death: ICD-10 — P94 2 out of 7 registries used, show all original rules.	62
4. Check minimum number of events None	62
5. Include endpoints None	62
6. Filter based on genotype QC (FinnGen only)	56

Control definitions (FinnGen only)

Control exclude: P16_OTH_DISORD_ORIGINA_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P9
Name in latin: Dystonia muscularis neonati

NAME	P16_DISORD_MUSCLE_TONE_NEWBO
CONTROL_EXCLUDE	P16_OTH_DISORD_ORIGINA_PERINA_PERIOD
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P94
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P94
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Disorders of muscle tone of newborn based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	2823	1183	1638
Only index persons	1569	650	919
Unadjusted period prevalence (%)
Whole population	0.04	0.03	0.05
Only index persons	0.03	0.02	0.04
Median age at first event (years)
Whole population	0.24	0.19	0.19
Only index persons	0.33	0.36	0.31

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	56	26	30
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	0.56	0.68	0.46

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
62: Matched controls
620

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

P94.2

ICD-10 Finland

Congenital hypotonia

727.3

38.4

P94.1

ICD-10 Finland

Congenital hypertonia

+∞

15.2

R62.0

ICD-10 Finland

Delayed milestone

8.0

12.7

R62.8

ICD-10 Finland

Other lack of expected normal physiological development

29.1

9.3

P94.9

ICD-10 Finland

Disorder of muscle tone of newborn, unspecified

+∞

8.5

F79.0

ICD-10 Finland

Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour

20.8

8.5

Z50.8

ICD-10 Finland

Care involving use of other rehabilitation procedures

7.1

6.9

Z3226

NOMESCO Finland

Physiotherapist

4.2

6.8

R4110

NOMESCO Finland

Physiotherapy

4.0

6.8

117

P94.0

ICD-10 Finland

Transient neonatal myasthenia gravis

+∞

6.3

P94.8

ICD-10 Finland

Other disorders of muscle tone of newborn

+∞

6.3

Z01.0

ICD-10 Finland

Examination of eyes and vision

4.0

6.3

P85

ICPC

Mental retardation

12.9

6.0

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3044640) Blood type and Crossmatch panel - Blood

142

2.77

3.68

5.6

3.3

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

8.92

2.80

2.8

1.0

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

191

2.25

2.47

5.6

3.3

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

4.50

2.44

3.3

1.8

—

(3023368) Bacteria identified in Blood by Culture

105

2.34

2.29

4.5

3.2

—

(1616796) Gas panel - Central venous blood

5.93

2.25

5.6

3.6

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

442

2.72

2.17

25.4

16.7

4.02

4.00

mmol/l

0.14

426

(3019550) Sodium [Moles/volume] in Serum or Plasma

443

2.69

2.16

23.4

16.8

139.20

139.32

mmol/l

0.16

431

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

141

2.15

2.09

9.2

15.5

0.03

0.91

mmol/l

0.67

105

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

4.03

1.98

1.3

1.4

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

4.03

1.98

1.3

1.4

—

(3002582) Erythrocytes [#/volume] in Urine

163

2.02

1.88

5.7

4.8

11.45

37.80

e6/l

0.80

127

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

244

2.00

1.88

13.5

19.2

1.24

mmol/l

0.01

229

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

122

2.09

1.85

7.0

3.3

—

(3019060) Gas panel - Arterial blood

4.08

1.75

1.6

4.6

—

(3012544) pH of Venous blood

125

2.03

1.72

9.2

13.8

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

260

1.92

1.68

20.5

7.2

108.68

106.77

ml/min/173m2

0.12

178

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

143

1.97

1.67

10.9

21.1

24.21

24.61

mmol/l

0.32

143

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

280

1.92

1.66

11.0

5.5

129.66

128.69

u/l

0.03

262

(40758558) Short blood count panel - Blood

178

1.92

1.65

8.5

8.1

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

341

2.00

1.65

4.0

3.1

14.37

14.47

pmol/l

0.07

311

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

119

2.00

1.63

6.0

12.2

23.10

23.32

mmol/l

0.25

119

(3041096) Erythrocytes [Presence] in Urine by Automated

103

2.05

1.63

4.7

4.0

—

(3042936) Bacteria identified in Isolate by Culture

2.41

1.62

1.8

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

121

0.36

1.60

2.2

2.4

—

(3030467) Casts [#/volume] in Urine by Automated count

146

1.91

1.56

5.3

4.3

0.14

0.09

e6/l

0.24

111

(36304419) Bacteria [Presence] in Urine

148

1.88

1.49

4.7

4.3

—

(3052851) Hemolysis interference index of Serum or Plasma

2.91

1.47

2.3

1.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.15

1.46

1.8

2.2

—

(3022313) Gas panel - Capillary blood

126

1.87

1.36

9.3

14.7

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

2.29

1.36

3.1

6.8

150.30

160.21

—

(3000991) Gas panel - Venous blood

118

1.88

1.35

10.3

14.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

206

1.77

1.34

8.8

5.7

0.00

estimate

—

(3037467) Urinalysis macro (dipstick) panel - Urine

293

1.77

1.32

5.9

4.5

—

(3020630) Protein [Mass/volume] in Serum or Plasma

2.93

1.31

1.2

1.9

63.90

59.41

g/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

171

1.77

1.31

6.2

4.9

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

137

1.81

1.28

4.4

4.2

—

(3018095) Leukocytes [#/volume] in Urine

191

1.73

1.25

8.0

5.7

19.82

29.75

e6/l

0.38

129

(40761511) CBC panel - Blood by Automated count

471

2.13

1.25

14.1

9.7

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

2.77

1.24

17.8

11.0

60.54

54.33

—

(3021901) Oxygen saturation in Capillary blood

2.77

1.24

3.8

17.0

—

(3009261) Glucose [Presence] in Urine by Test strip

210

1.72

1.23

5.3

4.1

0.00

estimate

—

(3012516) Albumin [Mass/volume] in Urine

2.20

1.20

5.5

2.9

63.99

95.52

mg/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.50

1.16

1.3

1.5

—

(3037121) Protein [Mass/volume] in Urine

2.33

1.12

21.6

6.0

0.36

0.33

g/l

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

2.33

1.12

2.4

2.0

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

171

1.66

1.05

6.8

3.9

66.75

69.59

nmol/l

0.27

160

(40761536) Microorganisms panel - Urine sediment

2.12

1.04

3.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

130

0.48

1.02

2.1

2.5

—

(3013512) EKG study

1.89

1.00

3.6

2.8

—

(21494755) Public health laboratory ask at order entry panel

0.00

0.98

0.0

1.3

—

(3002256) Pathology report gross observation

2.00

0.97

1.3

1.2

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.86

0.97

1.3

2.3

—

(3000492) Spirometry study

2.18

0.92

2.2

1.3

—

(4035726) Immunohistochemistry procedure

2.18

0.92

1.5

1.7

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

459

1.82

0.92

12.2

8.9

26.96

24.91

u/l

0.32

442

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

132

1.63

0.90

10.4

13.0

23.42

24.23

mmol/l

1.42

132

(3026008) Bacteria identified in Urine by Culture

116

1.64

0.86

1.8

2.6

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

142

0.57

0.82

2.3

2.0

—

(3037522) Nuclear Ab [Titer] in Serum

1.85

0.81

1.3

1.8

—

462.22

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.78

0.79

1.9

2.1

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.74

0.78

1.9

2.2

—

(3013115) Eosinophils [#/volume] in Blood

308

1.50

0.77

11.1

0.18

0.22

e9/l

0.56

254

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

490

1.79

0.74

21.3

13.0

22.33

22.57

mg/l

0.02

357

(3001604) Monocytes [#/volume] in Blood

300

1.48

0.73

10.9

10.2

0.60

0.59

e9/l

0.15

246

(3006315) Basophils [#/volume] in Blood

300

1.48

0.73

10.9

10.2

0.04

e9/l

0.36

246

(3022217) INR in Platelet poor plasma by Coagulation assay

121

1.56

0.72

11.1

7.6

1.12

1.26

inr

—

(3022145) Colonoscopy Study observation

2.00

0.72

1.4

1.7

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.59

0.69

4.9

3.8

1.01

0.41

e6/l

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

224

1.46

0.69

3.5

4.7

50.57

31.60

u/l

0.48

211

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.85

0.67

1.0

1.2

—

(3019198) Lymphocytes [#/volume] in Blood

313

1.45

0.67

10.9

10.0

3.39

2.37

e9/l

0.45

263

(3007164) IgA [Mass/volume] in Serum or Plasma

206

1.45

0.67

1.7

1.6

1.47

1.54

g/l

0.08

107

(3006504) Eosinophils/100 leukocytes in Blood

294

1.44

0.66

11.5

10.3

2.39

3.17

1.41

283

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

234

0.67

0.65

2.1

—

(36660697) Celiac disease serology panel - Serum

1.55

0.63

1.3

1.2

—

(3026782) Osmolality of Urine

1.55

0.63

5.4

3.6

562.79

582.29

mosm/kgh2o

0.14

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.55

0.62

2.6

2.0

—

(3014599) Egg white IgE Ab [Units/volume] in Serum

0.00

0.61

0.0

1.7

—

4.96

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.61

0.0

1.4

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.61

0.0

1.2

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.60

0.0

1.0

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.60

0.0

1.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.60

0.0

1.5

—

(3019069) Monocytes/100 leukocytes in Blood

297

1.41

0.60

11.7

10.4

7.44

8.40

1.16

288

(3018010) Neutrophils/100 leukocytes in Blood

307

1.41

0.60

11.4

9.9

49.58

48.69

0.13

297

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.59

0.0

1.9

—

(40761535) Cells panel - Urine sediment

0.00

0.59

0.0

3.2

—

(3044889) 12 lead EKG panel

191

1.42

0.59

2.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

100

1.52

0.58

5.1

4.0

0.71

2.53

e6/l

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

484

0.69

0.58

3.2

3.9

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

329

1.40

0.57

13.7

11.9

4.26

3.66

e9/l

0.75

272

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

1.55

0.57

3.1

12.5

94.11

89.67

—

(40760892) CBC W Ordered Manual Differential panel - Blood

289

1.39

0.57

11.6

11.1

—

(3003694) ABO and Rh group [Type] in Blood

165

1.41

0.55

1.7

—

(40768797) Stomach Pathology biopsy report

1.55

0.53

2.0

1.3

—

(3002030) Lymphocytes/100 leukocytes in Blood

313

1.36

0.50

11.5

10.0

34.83

35.90

0.16

304

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.51

0.45

1.0

1.1

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.51

0.45

5.5

6.8

6.00

5.83

umol/l

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.67

0.44

1.6

25.5

0.52

0.61

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.42

0.0

4.5

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

0.41

0.0

1.1

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

0.00

0.41

0.0

1.6

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.63

0.38

1.0

2.1

—

(3000494) Fungus identified in Specimen by Culture

1.42

0.33

1.3

1.4

—

(3019150) Specific gravity of Urine by Refractometry

103

1.33

0.31

3.5

4.1

1.02

1.01

kg/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

1.36

0.30

1.8

1.5

97.50

94.91

pmol/l

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.66

0.28

2.6

1.8

—

(1761868) Lipid panel - Serum or Plasma

1.22

0.26

2.8

2.0

—

(3021589) Normoblasts [#/volume] in Blood

301

1.21

0.24

16.7

11.4

0.37

0.00

e9/l

0.49

229

(40768804) Tissue Pathology biopsy report

117

1.25

0.23

1.9

1.8

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

1.24

0.22

1.4

1.3

—

7.37

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

110

0.79

0.22

1.6

1.7

—

(3029493) Herpes virus 6 DNA [Presence] in Blood by NAA with probe detection

0.00

0.21

0.0

4.9

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

0.00

0.21

0.0

1.4

—

5.65

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

2.5

—

29.97

—

(3041672) Baker's yeast Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.21

0.0

1.2

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.21

0.0

1.3

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.21

0.0

1.1

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.5

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.20

0.0

2.4

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.13

0.17

3.8

14.3

103.25

105.35

mmol/l

—

(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood

1.15

0.10

1.0

20.60

19.26

mmol/l

—

(3006598) pH of Arterial cord blood

1.15

0.10

1.0

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.87

0.07

1.7

1.4

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

120

1.11

0.05

5.3

3.4

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

143

0.97

0.00

1.5

2.1

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

1.8

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

-0.00

0.0

1.0

—

96.83

—

(3004809) Band form neutrophils/100 leukocytes in Blood

0.00

-0.00

0.0

6.1

—

1.71

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.4

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

8.2

—

(40768793) Breast Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(42528717) Cashew nut recombinant (rAna o) 3 IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

7.80

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

-0.00

0.0

1.0

—

(3038071) Oxygen [Partial pressure] in Mixed venous blood

0.00

-0.00

0.0

12.8

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

-0.00

0.0

1.1

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3007302) Hemoglobin [Mass/volume] in Mixed venous blood

0.00

-0.00

0.0

2.4

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

-0.00

0.0

1.2

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

-0.00

0.0

1.0

—

12.60

—

(3017115) Methotrexate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

34.4

—

0.69

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

2.6

—

(3040893) Potassium [Moles/volume] in Capillary blood

0.00

-0.00

0.0

5.4

—

4.36

—

(3042733) HLA Ab [Presence] in Serum

0.00

-0.00

0.0

2.1

—

(40767663) Brazil Nut recombinant (rBer e) 1 IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.3

—

6.67

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

-0.00

0.0

1.2

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

9.2

—

0.56

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

-0.00

0.0

1.1

—

205.89

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.6

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.8

—

(3017461) Flecainide [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

5.2

—

0.47

—

(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk

0.00

-0.00

0.0

1.1

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

0.27

—

(3036180) Methadone [Presence] in Urine

0.00

-0.00

0.0

3.1

—

(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood

0.00

-0.00

0.0

12.8

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

2.2

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(3042299) inFLIXimab [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

14.2

—

9.45

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.7

—

5.35

—

(3032352) Blasts [#/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

5.8

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_DISORD_MUSCLE_TONE_NEWBO and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_DISORD_MUSCLE_TONE_NEWBO.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_DISORD_MUSCLE_TONE_NEWBO – Disorders of muscle tone of newborn

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Disorders of muscle tone of newborn

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints