No definition available.
Physiological and behavioural disorders associated with sexual development and orientation
F5_SEXUAL
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
63 |
4. Check minimum number of eventsNone |
63 |
5. Include endpointsNone |
63 |
6. Filter based on genotype QC (FinnGen only) |
61 |
Control definitions (FinnGen only)
- Control exclude
- F5_PERSOBEH
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F63-F69
- Name in latin
- Perturbationes psychologicae et modi se gerendi ad formationem et orientationem sexualem adjunctae
Similar endpoints
↥List of similar endpoints to
Physiological and behavioural disorders associated with sexual development and orientation
based on the number of shared cases.
Similar with more cases:
- Disorders of adult personality and behaviour
- Any mental disorder
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 587 | 240 | 347 |
| Only index persons | 527 | 218 | 309 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | - | 35.04 | 23.08 |
| Only index persons | 26.20 | 32.73 | 21.59 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 61 | 38 | 23 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 33.74 | 35.76 | 30.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 63
- Matched controls
- 630
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N05AH04
ATC
quetiapine; oral
21.8
35.8
42
53
E66.01
ICD-10 Finland
Obesity due to excess calories
15.0
24.9
29
34
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
34.6
24.3
32
18
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
25.4
19.6
28
19
F32.9
ICD-10 Finland
Depressive episode, unspecified
10.2
18.0
27
43
N06AB04
ATC
citalopram; systemic
8.9
17.3
33
69
E66.9
ICD-10 Finland
Obesity, unspecified
40.8
16.4
20
7
F66.9
ICD-10 Finland
Psychosexual development disorder, unspecified
+∞
16.3
15
*
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
20.7
15.9
24
18
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
9.2
15.7
25
42
E66.8
ICD-10 Finland
Other obesity
21.8
15.6
23
16
N05AX12
ATC
aripiprazole; systemic
25.4
15.1
21
12
ZY010
NOMESCO Finland
Hospital outpatient
20.3
14.0
21
15
N06AX16
ATC
venlafaxine; oral
8.0
13.8
25
48
N06AB03
ATC
fluoxetine; oral
15.7
13.7
23
22
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
64.3
13.5
15
*
N05AF03
ATC
chlorprothixene; systemic
88.2
13.2
14
*
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
+∞
12.9
12
*
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
+∞
12.9
12
*
N05AX08
ATC
risperidone; systemic
15.9
12.8
21
19
N05AA02
ATC
levomepromazine; systemic
29.9
12.3
16
7
N05AH03
ATC
olanzapine; systemic
14.4
12.2
21
21
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
20.6
11.6
17
11
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
7.7
11.5
20
36
Z2446
NOMESCO Finland
Social worker
15.4
11.5
19
17
A10BA02
ATC
metformin; oral
6.3
11.4
27
67
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
12.8
11.1
20
22
N05BA04
ATC
oxazepam; oral
5.8
11.0
32
95
F66.01
ICD-10 Finland
Disorder in sexual maturity homosexual
+∞
10.7
10
*
F61.0
ICD-10 Finland
Mixed personality disorders
+∞
10.7
10
*
E66.00
ICD-10 Finland
Metabolic syndrome
21.3
10.5
15
9
F31.8
ICD-10 Finland
Other bipolar affective disorders
48.4
10.4
12
*
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
17.4
10.4
16
12
Z2445
NOMESCO Finland
Psychologist
19.2
10.1
15
10
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
12.5
9.5
17
18
N03AX09
ATC
lamotrigine; oral
15.9
9.5
15
12
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
22.9
9.4
13
7
T36
ICD-10 Finland
Poisoning by systemic antibiotics
22.9
9.4
13
7
N06AB06
ATC
sertraline; oral
5.9
9.2
21
49
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
20.0
9.0
13
8
N06AX12
ATC
bupropion; oral
10.0
9.0
18
24
Z3226
NOMESCO Finland
Physiotherapist
5.5
8.9
23
60
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
6.0
8.8
19
42
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
32.7
8.8
11
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
32.7
8.8
11
*
Z3231
NOMESCO Finland
Registered nurse
4.8
8.5
29
95
3020A
ICD-9 Finland
Sexual deviations and disorders, Ego-dystonic homosexuality
+∞
8.5
8
*
F66.00
ICD-10 Finland
Disorder in sexual maturity heterosexual
+∞
8.5
8
*
N05BA06
ATC
lorazepam; systemic, sublingual
20.7
8.5
12
7
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
26.1
8.3
11
5
IGY99
NOMESCO Finland
Other psychiatric treatment contact
26.1
8.3
11
5
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
16.0
8.3
13
10
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
11.2
8.1
15
17
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
18.1
8.1
12
8
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
12.5
8.0
14
14
F34.1
ICD-10 Finland
Dysthymia
12.5
8.0
14
14
N06AX03
ATC
mianserin; oral
21.8
7.9
11
6
N05AH02
ATC
clozapine; systemic
21.8
7.9
11
6
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
11.6
7.8
14
15
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
13.3
7.7
13
12
T90
ICPC
Diabetes non-insulin dependent
5.2
7.7
20
52
ZY000
NOMESCO Finland
Hospital inpatient
90.3
7.6
8
*
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
90.3
7.6
8
*
A10BJ06
ATC
semaglutide; parenteral
14.5
7.4
12
10
F29
ICD-10 Finland
Unspecified nonorganic psychosis
14.5
7.4
12
10
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
14.5
7.4
12
10
F66.80
ICD-10 Finland
Other specified disorder of psychosexual development heterosexual
+∞
7.4
7
*
F60.9
ICD-10 Finland
Personality disorder, unspecified
+∞
7.4
7
*
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
34.4
7.4
9
*
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
34.4
7.4
9
*
N06AB10
ATC
escitalopram; oral
4.3
7.3
28
99
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
10.2
7.3
14
17
103
Kela drug reimbursment
Diabetes, insulin-treated
4.7
7.2
22
65
N05BE01
ATC
buspirone; oral
16.3
7.2
11
8
IGY02
NOMESCO Finland
Psychiatric monitoring contact
16.3
7.2
11
8
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
19.4
7.0
10
6
N03AG01
ATC
valproic acid; systemic, rectal
10.6
7.0
13
15
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
45.0
6.9
8
*
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
12.0
6.9
12
12
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
12.0
6.9
12
12
F20.9
ICD-10 Finland
Schizophrenia, unspecified
14.5
6.9
11
9
215
Kela drug reimbursment
Diabetes, non-insulin-treated
4.6
6.9
21
62
P03
ICPC
Feeling depressed
5.0
6.8
18
47
N06AX11
ATC
mirtazapine; oral
3.9
6.7
32
131
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
77.4
6.6
7
*
N05CD07
ATC
temazepam; oral
9.3
6.5
13
17
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
30.0
6.4
8
*
F66.09
ICD-10 Finland
Disorder of sexual maturity other or indefinite
+∞
6.3
6
*
N05AB03
ATC
perphenazine; systemic, rectal
14.5
6.3
10
8
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
10.8
6.1
11
12
T82
ICPC
Obesity
12.9
6.0
10
9
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
36
177
3.41
5.42
14.6
5.4
1.21
1.22
mmol/l
0.20
31
153
8
6
14.99
5.23
20.8
9.5
919.50
1249.00
nmol/l
—
8
6
34
172
3.12
4.71
8.3
4.0
34.67
37.76
g/l
3.22
34
167
29
140
2.99
4.28
3.0
1.6
91.28
97.49
pmol/l
0.31
19
77
11
27
4.71
3.60
1.5
1.4
—
—
—
0
0
28
144
2.70
3.55
4.8
2.6
—
—
—
0
0
29
176
2.20
2.37
9.7
11.4
1.00
1.23
inr
—
7
48
8
24
3.66
2.27
1.9
1.9
2.02
2.60
mg/l
—
8
15
10
36
3.11
2.26
3.1
6.2
105.50
103.67
mmol/l
—
10
36
16
77
2.44
2.20
5.4
3.5
830.00
99.08
ng/l
—
10
49
6
18
3.57
1.79
1.8
1.3
—
—
—
0
0
5
15
3.52
1.55
1.0
1.2
—
—
—
0
0
45
355
1.94
1.53
12.1
6.8
85.38
73.89
u/l
1.19
45
325
10
49
2.24
1.30
6.4
1.9
—
—
—
0
0
11
61
1.97
1.06
6.3
2.1
—
—
—
0
0
16
103
1.74
1.00
3.9
2.3
—
—
—
0
0
54
480
1.87
0.94
21.1
8.5
90.65
92.37
ml/min/173m2
0.18
47
381
30
234
1.54
0.87
6.3
4.5
0.00
0.00
estimate
—
5
41
19
133
1.61
0.87
1.6
1.3
0.57
0.76
u/ml
—
7
27
8
47
1.80
0.84
3.1
1.3
—
—
—
0
0
14
91
1.69
0.84
1.4
1.2
34.60
27.51
iu/ml
—
5
21
30
239
1.49
0.77
5.0
3.4
0.00
0.00
estimate
—
5
43
5
26
2.00
0.72
3.8
2.7
—
184.05
—
0
10
6
101
0.55
0.69
1.3
1.4
—
—
—
0
0
5
30
1.72
0.63
11.0
3.1
—
—
—
0
0
0
22
0.00
0.60
0.0
1.3
—
—
—
0
0
27
221
1.39
0.56
5.9
2.6
140.44
80.64
ug/l
0.51
27
213
6
39
1.59
0.54
1.2
1.0
—
—
—
0
0
16
120
1.45
0.53
4.3
2.4
—
—
—
0
0
5
81
0.58
0.50
3.2
4.0
—
20.06
—
0
28
39
434
0.73
0.49
3.9
3.9
—
—
—
0
0
7
48
1.51
0.49
3.7
1.4
—
—
—
0
0
10
70
1.51
0.45
3.2
1.6
—
—
—
0
0
56
528
1.54
0.44
28.1
10.4
21.86
20.68
mg/l
0.11
48
394
0
15
0.00
0.42
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.0
—
3.13
—
0
10
0
18
0.00
0.40
0.0
2.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
19
154
1.33
0.40
3.9
3.4
35.25
21.80
ng/l
0.31
12
82
23
193
1.30
0.38
4.5
3.3
—
—
—
0
0
12
91
1.39
0.37
2.8
3.1
533.83
768.85
ng/l
0.32
12
73
27
237
1.24
0.30
3.2
2.3
—
—
—
0
0
14
115
1.28
0.26
2.6
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
1.83
—
0
6
15
130
1.20
0.17
3.1
3.8
0.00
0.03
estimate
—
5
39
15
151
0.99
0.00
1.5
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
13.22
—
0
9
Mortality – FinRegistry
↥Association
Association between endpoint F5_SEXUAL and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have F5_SEXUAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: F5_SEXUAL – Physiological and behavioural disorders associated with sexual development and orientation
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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