Other fusion of spine

M13_SPINEFUSION

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M43.2 Cause of death: ICD-10 — M43.2 2 out of 7 registries used, show all original rules.	62
4. Check minimum number of events None	62
5. Include endpoints None	62
6. Filter based on genotype QC (FinnGen only)	62

Control definitions (FinnGen only)

Control exclude: M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M43
Name in latin: Alia fusio columnae vertebralis

NAME	M13_SPINEFUSION
CONTROL_EXCLUDE	M13_DORSOPATHY
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M432
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M432
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other fusion of spine based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	412	227	184
Only index persons	396	221	175
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	51.00	53.38	48.01
Only index persons	50.22	53.20	46.46

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	62	41	21
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	53.51	54.12	52.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
62: Matched controls
620

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M43.2

ICD-10 Finland

Other fusion of spine

+∞

89.0

M47.2

ICD-10 Finland

Other spondylosis with radiculopathy

+∞

25.8

N03AX16

ATC

[U] pregabalin

12.7

22.9

NA3BG

NOMESCO Finland

Lumbar spine MRI examination with high intensity magnet

83.2

20.5

N03AX12

ATC

[U] gabapentin; oral

10.6

17.1

M43.1

ICD-10 Finland

Spondylolisthesis

114.6

16.5

NA3AA

NOMESCO Finland

Lumbar spine X-ray examination without contrast

30.9

16.0

M54.5

ICD-10 Finland

Low back pain

8.3

16.0

NA3EA

NOMESCO Finland

Lumbar spine X-ray examination with flexion

193.8

15.2

N02AX02

ATC

tramadol; systemic, rectal

8.4

15.0

140

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

41.2

14.9

NAG62

NOMESCO Finland

Posterior fusion of lumbar spine with fixation, 2-3 vertebraea

+∞

14.1

NA3CG

NOMESCO Finland

Lumbar spine extensive MRI examination with high intensity magnet

177.2

14.1

M51.3

ICD-10 Finland

Other specified intervertebral disc degeneration

52.7

13.9

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

15.2

12.5

M43.0

ICD-10 Finland

Spondylolysis

+∞

10.7

M54.4

ICD-10 Finland

Lumbago with sciatica

9.1

9.6

M48.0

ICD-10 Finland

Spinal stenosis

58.6

9.0

NA1BG

NOMESCO Finland

Cervical spine MRI examination with high intensity magnet

58.6

9.0

M47.80

ICD-10 Finland

Other spondylosis, multiple sites in spine

58.6

9.0

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

5.9

8.9

ABC36

NOMESCO Finland

Decompression of lumbar nerve roots

+∞

8.5

M53.1

ICD-10 Finland

Cervicobrachial syndrome

10.4

8.2

L03

ICPC

Low back symptom/complaint

4.8

8.0

NA3AD

NOMESCO Finland

Lumbar spine and sacrum CT examination

51.8

7.9

L01

ICPC

Neck symptom/complaint

7.6

7.9

M01AB05

ATC

diclofenac; systemic, rectal

6.7

7.6

334

SHA03

NOMESCO Finland

Stomatognathic treatment, demanding

25.9

6.9

M53.2

ICD-10 Finland

Spinal instabilities

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

132

2.85

3.83

2.4

1.9

159.07

168.10

u/l

0.06

124

(40768797) Stomach Pathology biopsy report

3.08

3.27

1.3

1.2

—

(36304419) Bacteria [Presence] in Urine

111

2.70

3.27

3.0

2.3

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

220

2.52

3.11

4.4

5.9

1.22

mmol/l

0.15

186

(3013115) Eosinophils [#/volume] in Blood

248

2.54

3.09

4.6

5.7

0.21

0.19

e9/l

0.50

229

(3006315) Basophils [#/volume] in Blood

241

2.49

3.00

4.6

5.1

0.05

0.04

e9/l

0.67

220

(3031040) Bacteria [#/volume] in Urine by Automated count

309

2.66

2.99

6.7

3.7

—

106.00

—

(3001604) Monocytes [#/volume] in Blood

242

2.47

2.96

4.5

5.1

0.61

0.56

e9/l

0.47

220

(42529406) Shigella sp [Presence] in Stool by Culture

5.48

2.81

1.1

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

5.48

2.81

1.1

1.2

—

(3014051) Protein [Presence] in Urine by Test strip

8.92

2.80

4.0

1.5

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

5.11

2.68

1.3

1.2

—

(3025941) Bacteria identified in Stool by Culture

3.64

2.66

1.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

3.87

2.60

1.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

180

2.29

2.57

2.2

1.8

86.74

100.42

pmol/l

0.73

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

159

2.24

2.38

3.0

2.6

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.33

2.25

1.6

1.4

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

282

2.18

2.20

6.1

10.0

4.19

4.01

e9/l

0.20

248

(3022621) pH of Urine by Test strip

3.52

2.18

3.4

2.6

—

(3037467) Urinalysis macro (dipstick) panel - Urine

338

2.21

2.03

4.7

3.7

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

393

2.41

2.00

4.5

4.1

14.88

15.02

pmol/l

0.14

353

(3045414) Leukocytes [Presence] in Urine

4.03

1.98

3.5

1.3

—

(3044640) Blood type and Crossmatch panel - Blood

146

2.05

1.88

2.8

1.9

—

(3021589) Normoblasts [#/volume] in Blood

207

2.00

1.88

5.1

9.0

0.00

e9/l

-0.00

172

(3000330) Specific gravity of Urine by Test strip

3.29

1.86

4.1

4.7

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.25

1.85

2.0

3.2

12.10

172.86

ng/l

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

107

2.12

1.81

1.5

0.76

1.04

mg/l

0.63

(40760892) CBC W Ordered Manual Differential panel - Blood

223

1.90

1.66

5.1

6.2

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.78

1.65

4.4

3.4

25.04

25.14

mmol/l

—

(3018095) Leukocytes [#/volume] in Urine

161

1.93

1.63

3.1

2.8

10.25

78.90

e6/l

1.67

105

(3014111) Lactate [Moles/volume] in Serum or Plasma

3.21

1.62

5.0

3.8

1.35

1.55

mmol/l

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

3.21

1.62

1.0

—

(3000991) Gas panel - Venous blood

3.05

1.54

5.0

3.9

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

106

1.98

1.50

2.9

1.8

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.40

1.49

2.0

1.5

—

(3026008) Bacteria identified in Urine by Culture

148

1.88

1.49

4.6

2.7

—

(3018010) Neutrophils/100 leukocytes in Blood

229

1.82

1.48

4.7

5.3

57.26

57.06

0.03

221

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.29

1.36

3.6

4.3

101.80

104.79

mmol/l

—

(3002030) Lymphocytes/100 leukocytes in Blood

234

1.76

1.34

4.8

5.4

28.52

28.12

0.07

228

(3014007) Fractional oxyhemoglobin in Arterial blood

2.93

1.31

5.8

5.6

95.70

94.88

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.44

1.22

1.2

1.9

—

(40761535) Cells panel - Urine sediment

2.50

1.16

3.7

4.3

—

(40758558) Short blood count panel - Blood

117

1.76

1.09

4.4

6.2

—

(3023368) Bacteria identified in Blood by Culture

109

1.77

1.08

4.2

3.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

180

1.65

1.05

3.8

3.9

—

(3000494) Fungus identified in Specimen by Culture

2.02

1.03

1.2

1.4

—

(3015736) pH of Urine

182

1.63

1.00

3.1

3.5

—

5.73

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.74

0.95

4.1

3.2

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.83

0.93

2.1

2.8

0.86

0.84

mmol/l

0.46

(3012516) Albumin [Mass/volume] in Urine

140

1.63

0.92

2.9

3396.92

553.81

mg/l

0.38

(3042936) Bacteria identified in Isolate by Culture

1.81

0.85

1.6

1.9

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

227

1.52

0.82

2.8

2.2

—

(3009508) Creatinine [Moles/volume] in Urine

145

1.56

0.79

3.0

2.8

8.97

8.22

mmol/l

0.27

121

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.95

0.76

2.9

1.5

343.71

400.91

nmol/l

—

(4200892) Spirometry reversibility

1.89

0.75

1.7

1.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

138

1.54

0.74

4.8

3.6

—

(3037522) Nuclear Ab [Titer] in Serum

1.72

0.74

1.4

—

501.18

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

148

1.52

0.72

2.0

2.2

64.65

57.12

u/l

0.45

137

(3020682) Albumin/Creatinine [Ratio] in Urine

150

1.49

0.67

3.6

3.3

0.78

8.27

mg/mmol

1.18

(3022217) INR in Platelet poor plasma by Coagulation assay

217

1.43

0.64

13.0

12.0

1.21

1.23

inr

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.84

0.60

2.7

1.6

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.50

0.55

4.4

6.8

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.59

0.54

2.8

1.7

—

(1761868) Lipid panel - Serum or Plasma

215

0.71

0.50

3.2

3.0

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.56

0.50

1.4

1.8

13.77

13.08

umol/l

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.59

0.50

1.6

1.7

—

(3003694) ABO and Rh group [Type] in Blood

150

0.68

0.49

1.5

1.3

—

(3044889) 12 lead EKG panel

365

1.36

0.48

3.7

3.4

—

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

0.42

0.0

4.1

—

3.95

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

0.42

0.0

2.4

—

54.11

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.43

0.41

1.3

1.4

—

(3012544) pH of Venous blood

1.42

0.39

1.2

2.6

—

(3007164) IgA [Mass/volume] in Serum or Plasma

1.40

0.37

1.0

1.4

2.60

2.54

g/l

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

525

1.42

0.34

5.2

4.3

1.49

1.51

mmol/l

0.15

476

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

187

1.27

0.33

4.2

4.0

11.67

48.23

ng/l

1.27

121

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.36

0.30

2.1

3.1

0.99

1.06

mmol/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.22

0.26

1.8

1.7

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

539

1.40

0.26

5.6

4.8

2.73

2.78

mmol/l

0.15

491

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

530

1.33

0.24

5.2

4.3

4.61

4.71

mmol/l

0.32

486

(3002173) Hemoglobin [Mass/volume] in Arterial blood

1.31

0.23

7.8

7.1

117.80

121.13

g/l

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

1.28

0.23

1.2

0.38

1.47

u/ml

—

(3016502) Oxygen saturation in Arterial blood

1.24

0.22

7.8

7.0

96.24

95.82

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

1.21

0.22

7.8

6.5

4.86

4.98

kpa

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.21

0.22

1.6

1.5

—

(40761536) Microorganisms panel - Urine sediment

1.21

0.22

5.6

3.7

—

(3027801) Oxygen [Partial pressure] in Arterial blood

1.21

0.22

7.8

6.5

12.40

11.91

kpa

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.3

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.21

0.0

2.7

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.6

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.3

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

247.04

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.5

—

(40768795) Lymph node Pathology biopsy report

0.00

0.21

0.0

1.0

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.21

0.0

1.4

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.6

—

(3019225) pH of Specimen

1.28

0.21

4.5

4.1

—

(3016879) Cocaine [Presence] in Urine

0.00

0.21

0.0

1.3

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.21

0.0

1.3

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.20

0.0

1.3

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.20

0.0

1.3

—

(3027008) Opiates [Presence] in Urine

0.00

0.20

0.0

1.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.17

0.19

2.2

3.2

—

(3022145) Colonoscopy Study observation

1.21

0.19

1.1

1.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

327

1.16

0.17

2.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.16

0.17

1.6

1.7

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.16

0.16

1.7

1.4

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

504

1.20

0.13

4.5

3.9

1.25

mmol/l

0.01

454

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.18

0.10

1.4

—

(3003396) Base excess in Arterial blood by calculation

1.09

0.10

7.8

6.5

0.28

1.77

mmol/l

—

(3000492) Spirometry study

1.09

0.10

1.0

1.5

—

(4035726) Immunohistochemistry procedure

1.09

0.10

1.0

1.4

—

(40768804) Tissue Pathology biopsy report

221

1.06

0.03

2.3

1.9

—

(3013512) EKG study

155

0.96

0.00

3.3

3.7

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.4

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.5

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.2

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.5

—

(3017354) Segmented neutrophils/100 leukocytes in Blood

0.00

-0.00

0.0

2.6

—

56.60

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.6

—

(3000012) Reticulocyte production index

0.00

-0.00

0.0

2.6

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

6.8

—

1080.00

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.3

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.6

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

-0.00

0.0

1.6

—

13.00

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3035880) pH of Pleural fluid

0.00

-0.00

0.0

1.0

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.5

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

203.33

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

2.3

—

32.00

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

-0.00

0.0

1.3

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

-0.00

0.0

1.1

—

(3002256) Pathology report gross observation

0.97

-0.00

1.1

1.2

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

1.57

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

3.7

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3042631) Mycobacterium sp identified in Specimen

0.00

-0.00

0.0

1.7

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

0.76

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.5

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3004809) Band form neutrophils/100 leukocytes in Blood

0.00

-0.00

0.0

2.6

—

1.00

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

7.2

—

61.94

—

(3019309) Folate [Moles/volume] in Red Blood Cells

0.98

-0.00

1.9

1.6

783.43

1142.71

nmol/l

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3040151) Glucose [Moles/volume] in Capillary blood

0.00

-0.00

0.0

2.0

—

5.42

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

2.0

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.0

—

(3011288) Drugs identified in Urine by Screen method

0.00

-0.00

0.0

1.3

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.3

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.5

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

3.4

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.0

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.6

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.2

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

9.4

—

2318.20

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.5

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_SPINEFUSION and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_SPINEFUSION.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: M13_SPINEFUSION – Other fusion of spine

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other fusion of spine

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints