Other fusion of spine

M13_SPINEFUSION

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M43.2 Cause of death: ICD-10 — M43.2 2 out of 7 registries used, show all original rules.	59
4. Check minimum number of events None	59
5. Include endpoints None	59
6. Filter based on genotype QC (FinnGen only)	59

Control definitions (FinnGen only)

Control exclude: M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M43
Name in latin: Alia fusio columnae vertebralis

NAME	M13_SPINEFUSION
CONTROL_EXCLUDE	M13_DORSOPATHY
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M432
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M432
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other fusion of spine based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	412	227	184
Only index persons	396	221	175
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	51.00	53.38	48.01
Only index persons	50.22	53.20	46.46

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	59	40	19
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	53.20	53.62	52.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
52: Matched controls
519

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M43.2

ICD-10 Finland

Other fusion of spine

+∞

74.4

M47.2

ICD-10 Finland

Other spondylosis with radiculopathy

+∞

21.3

NA3BG

NOMESCO Finland

Lumbar spine MRI examination with high intensity magnet

245.7

17.7

M43.1

ICD-10 Finland

Spondylolisthesis

+∞

15.3

NA3AA

NOMESCO Finland

Lumbar spine X-ray examination without contrast

49.0

14.6

M51.3

ICD-10 Finland

Other specified intervertebral disc degeneration

186.8

14.2

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

93.4

13.3

N03AX12

ATC

gabapentin; oral

22.2

13.1

NA3EA

NOMESCO Finland

Lumbar spine X-ray examination with flexion

+∞

13.0

N03AX16

ATC

pregabalin; oral

11.3

12.1

NA3CG

NOMESCO Finland

Lumbar spine extensive MRI examination with high intensity magnet

152.4

12.0

NAG62

NOMESCO Finland

Posterior fusion of lumbar spine with fixation, 2-3 vertebraea

+∞

11.9

N02AX02

ATC

tramadol; systemic, rectal

8.5

11.6

116

NA1BG

NOMESCO Finland

Cervical spine MRI examination with high intensity magnet

+∞

10.8

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

16.2

10.5

M54.5

ICD-10 Finland

Low back pain

8.0

10.3

M43.0

ICD-10 Finland

Spondylolysis

+∞

9.7

M54.4

ICD-10 Finland

Lumbago with sciatica

9.2

8.4

M53.1

ICD-10 Finland

Cervicobrachial syndrome

11.9

7.3

NA3AD

NOMESCO Finland

Lumbar spine and sacrum CT examination

46.2

7.0

M47.80

ICD-10 Finland

Other spondylosis, multiple sites in spine

30.8

6.4

M53.2

ICD-10 Finland

Spinal instabilities

+∞

6.4

ABC36

NOMESCO Finland

Decompression of lumbar nerve roots

+∞

6.4

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

6.5

6.4

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768797) Stomach Pathology biopsy report

3.11

3.29

1.3

1.2

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

128

2.65

3.18

1.9

2.0

152.6

169.0

u/l

0.11

121

(3013115) Eosinophils [#/volume] in Blood

241

2.62

3.09

4.7

5.5

0.2

e9/l

0.47

220

(3006315) Basophils [#/volume] in Blood

234

2.56

2.99

4.6

4.9

0.0

e9/l

0.76

209

(42529406) Shigella sp [Presence] in Stool by Culture

5.94

2.96

1.1

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

5.94

2.96

1.1

1.2

—

(3001604) Monocytes [#/volume] in Blood

235

2.54

2.95

4.6

4.9

0.6

e9/l

0.47

209

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

5.51

2.82

1.3

1.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

4.23

2.81

1.4

—

(36304419) Bacteria [Presence] in Urine

113

2.51

2.72

2.9

2.3

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

175

2.29

2.47

2.2

1.8

86.7

101.6

pmol/l

0.81

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.60

2.43

1.6

1.4

—

(3025941) Bacteria identified in Stool by Culture

3.60

2.43

1.2

—

(3031040) Bacteria [#/volume] in Urine by Automated count

301

2.37

2.32

6.9

3.8

—

106.0

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

273

2.26

2.25

6.2

10.0

4.3

4.0

e9/l

0.33

239

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

156

2.19

2.8

2.6

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

100

2.33

2.17

1.5

0.8

1.0

mg/l

0.56

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.21

1.68

2.1

3.2

13.1

183.7

ng/l

—

(3022621) pH of Urine by Test strip

2.91

1.64

3.1

2.4

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.53

1.63

2.0

1.4

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

3.22

1.62

5.0

3.8

1.4

1.2

mmol/l

—

(3021589) Normoblasts [#/volume] in Blood

207

1.91

1.62

5.2

8.6

0.0

e9/l

0.00

169

(3045414) Leukocytes [Presence] in Urine

3.54

1.55

3.2

1.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.54

1.55

4.4

3.2

25.0

25.1

mmol/l

—

(3000330) Specific gravity of Urine by Test strip

3.06

1.55

4.0

4.7

—

(3000991) Gas panel - Venous blood

3.06

1.55

5.0

3.9

—

(3026008) Bacteria identified in Urine by Culture

139

1.93

1.52

4.8

2.7

—

(3006504) Eosinophils/100 leukocytes in Blood

220

1.86

1.51

4.9

2.9

2.7

0.23

210

(3037467) Urinalysis macro (dipstick) panel - Urine

329

1.96

1.50

4.7

3.6

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.92

1.47

1.2

1.1

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

385

2.09

1.44

4.6

4.1

14.9

15.0

pmol/l

0.08

345

(3018010) Neutrophils/100 leukocytes in Blood

224

1.81

1.39

4.8

5.1

57.7

56.8

0.18

215

(3023368) Bacteria identified in Blood by Culture

101

1.96

1.39

4.2

3.2

—

(3014007) Fractional oxyhemoglobin in Arterial blood

3.11

1.39

5.8

4.5

95.7

94.8

—

(3044640) Blood type and Crossmatch panel - Blood

143

1.86

1.38

3.0

1.9

—

(3018095) Leukocytes [#/volume] in Urine

161

1.83

1.36

2.9

2.8

10.7

90.1

e6/l

1.71

106

(3002030) Lymphocytes/100 leukocytes in Blood

229

1.75

1.25

4.9

5.2

28.6

28.4

0.04

220

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.78

1.24

1.0

—

(3042936) Bacteria identified in Isolate by Culture

2.10

1.21

1.6

2.0

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

2.27

1.10

2.6

2.2

—

20.6

—

(3000494) Fungus identified in Specimen by Culture

2.07

1.09

1.2

1.4

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.93

1.06

2.1

2.8

0.9

0.8

mmol/l

0.55

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

103

1.76

1.01

3.2

1.7

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

174

1.64

0.99

3.9

—

(40761535) Cells panel - Urine sediment

2.36

0.96

4.2

4.4

—

(42870588) Differential panel, method unspecified - Blood

158

1.63

0.93

5.3

4.2

—

(40758558) Short blood count panel - Blood

117

1.64

0.84

4.5

6.3

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

144

1.59

0.83

2.0

2.2

64.7

58.3

u/l

0.36

132

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.91

0.81

2.7

1.8

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.00

0.79

0.0

1.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.66

0.78

4.0

3.3

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.95

0.77

2.9

1.5

343.7

400.9

nmol/l

—

(4010399)

1.90

0.76

1.7

1.4

—

(3037522) Nuclear Ab [Titer] in Serum

1.68

0.63

1.4

—

384.0

—

(3012516) Albumin [Mass/volume] in Urine

134

1.49

0.63

2.7

2.8

3679.6

39.2

mg/l

0.47

(3003694) ABO and Rh group [Type] in Blood

146

0.62

1.4

—

(3032080) INR in Blood by Coagulation assay

181

1.44

0.61

5.0

8.7

1.2

inr

—

(3041096) Erythrocytes [Presence] in Urine by Automated

135

1.48

0.61

5.1

3.4

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.65

0.60

1.4

1.7

13.8

13.5

umol/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.69

0.57

2.8

1.9

—

(1761868) Lipid panel - Serum or Plasma

205

0.70

0.52

3.3

3.0

—

(3009508) Creatinine [Moles/volume] in Urine

139

1.42

0.52

2.8

2.7

8.4

8.2

mmol/l

0.07

117

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.48

0.47

1.3

1.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

143

1.37

0.44

3.6

3.4

0.8

5.8

mg/mmol

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.44

0.44

4.8

7.1

—

(3012544) pH of Venous blood

1.56

0.42

1.2

2.7

—

(40768793) Breast Pathology biopsy report

0.00

0.42

0.0

1.1

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

221

1.32

0.41

3.8

3.5

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.48

0.37

1.7

—

(3044889) 12 lead EKG panel

357

1.27

0.32

3.7

3.4

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.27

0.28

1.6

1.7

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

182

1.24

0.26

4.3

3.9

10.5

49.5

ng/l

1.32

116

(40761536) Microorganisms panel - Urine sediment

1.24

0.22

5.6

3.6

—

(3027801) Oxygen [Partial pressure] in Arterial blood

1.21

0.22

7.8

5.7

12.4

11.9

kpa

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

1.21

0.22

7.8

5.7

4.9

5.0

kpa

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.5

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.4

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.4

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.21

0.0

2.2

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.7

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

247.0

—

(40768795) Lymph node Pathology biopsy report

0.00

0.21

0.0

1.0

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

6.9

—

50.8

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.21

0.0

2.0

—

(3016879) Cocaine [Presence] in Urine

0.00

0.21

0.0

2.0

—

(3027008) Opiates [Presence] in Urine

0.00

0.20

0.0

1.9

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.20

0.0

1.9

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.20

0.0

1.9

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

0.20

0.0

2.6

—

54.1

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.26

0.19

2.3

3.1

1.0

1.1

mmol/l

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.15

0.16

1.7

1.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

112

1.21

0.16

3.3

5.6

—

(3009542) Hematocrit [Volume Fraction] of Blood

472

1.23

0.16

18.1

11.4

38.6

40.3

0.73

350

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

503

1.28

0.16

4.9

4.3

1.5

mmol/l

0.18

454

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

311

1.14

0.13

2.5

2.7

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

1.18

0.11

1.2

0.4

0.6

u/ml

—

(3000492) Spirometry study

1.18

0.10

1.0

1.5

—

(3019225) pH of Specimen

1.15

0.10

5.0

4.1

—

(3003396) Base excess in Arterial blood by calculation

1.07

0.09

7.8

5.8

0.3

1.9

mmol/l

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

517

1.25

0.08

5.3

4.8

2.8

mmol/l

0.02

469

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.11

0.08

1.8

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

508

1.20

0.07

5.0

4.3

4.7

mmol/l

0.17

464

(40768804) Tissue Pathology biopsy report

220

1.07

0.04

2.3

2.0

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

484

1.07

0.01

4.3

3.9

1.3

mmol/l

0.03

434

(3013512) EKG study

146

0.95

0.01

3.2

3.6

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.2

—

(3035880) pH of Pleural fluid

0.00

0.0

1.0

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.0

2.0

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.5

—

(4146454)

0.00

0.0

3.2

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

0.0

1.1

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.1

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.5

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

0.8

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.7

—

13.2

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

9.4

—

2318.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.96

0.00

2.4

3.2

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

4.0

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

2.4

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.5

—

(3019309) Folate [Moles/volume] in Red Blood Cells

0.97

0.00

1.9

1.7

783.4

1151.2

nmol/l

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

3.8

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.2

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.0

1.1

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.6

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

6.8

—

1080.0

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

2.6

—

31.2

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.4

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

1.2

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.5

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.5

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.0

1.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.6

—

(4268621)

0.00

0.0

1.8

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.1

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.2

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.0

3.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.5

—

(3002256) Pathology report gross observation

0.97

0.00

1.1

1.2

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

2.0

—

(3022145) Colonoscopy Study observation

1.02

0.00

1.2

1.4

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.0

1.8

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.3

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.0

1.7

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

4.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

7.2

—

61.9

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.9

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.9

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.6

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.9

—

(4306422)

0.00

0.0

1.2

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.7

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_SPINEFUSION and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_SPINEFUSION.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: M13_SPINEFUSION – Other fusion of spine

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other fusion of spine

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints