Other fusion of spine

M13_SPINEFUSION

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M43.2
  • Cause of death: ICD-10 M43.2

2 out of 7 registries used, show all original rules.

59

4. Check minimum number of events

None

59

5. Include endpoints

None

59

6. Filter based on genotype QC (FinnGen only)

59

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M43
Name in latin
Alia fusio columnae vertebralis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 412 227 184
Only index persons 396 221 175
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 51.00 53.38 48.01
Only index persons 50.22 53.20 46.46

-FinnGen-

Key figures

All Female Male
Number of individuals 59 40 19
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 53.20 53.62 52.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
52
Matched controls
519
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M43.2
ICD-10 Finland
Other fusion of spine
+∞
74.4
52
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
+∞
21.3
19
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
245.7
17.7
17
*
M43.1
ICD-10 Finland
Spondylolisthesis
+∞
15.3
14
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
49.0
14.6
17
5
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
186.8
14.2
14
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
93.4
13.3
14
*
N03AX12
ATC
gabapentin; oral
22.2
13.1
19
13
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
+∞
13.0
12
*
N03AX16
ATC
pregabalin; oral
11.3
12.1
25
39
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
152.4
12.0
12
*
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
+∞
11.9
11
*
N02AX02
ATC
tramadol; systemic, rectal
8.5
11.6
37
116
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
+∞
10.8
10
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
16.2
10.5
17
15
M54.5
ICD-10 Finland
Low back pain
8.0
10.3
28
66
M43.0
ICD-10 Finland
Spondylolysis
+∞
9.7
9
*
M54.4
ICD-10 Finland
Lumbago with sciatica
9.2
8.4
18
28
M53.1
ICD-10 Finland
Cervicobrachial syndrome
11.9
7.3
13
14
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
46.2
7.0
8
*
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
30.8
6.4
8
*
M53.2
ICD-10 Finland
Spinal instabilities
+∞
6.4
6
*
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
+∞
6.4
6
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
6.5
6.4
17
36

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(40768797) Stomach Pathology biopsy report
16
63
3.11
3.29
1.3
1.2
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
25
128
2.65
3.18
1.9
2.0
u/l
152.6
169.0
0.11
25
121
(3013115) Eosinophils [#/volume] in Blood
38
241
2.62
3.09
4.7
5.5
e9/l
0.2
0.2
0.47
33
220
(3006315) Basophils [#/volume] in Blood
37
234
2.56
2.99
4.6
4.9
e9/l
0.0
0.0
0.76
30
209
(42529406) Shigella sp [Presence] in Stool by Culture
7
13
5.94
2.96
1.1
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
7
13
5.94
2.96
1.1
1.2
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
37
235
2.54
2.95
4.6
4.9
e9/l
0.6
0.6
0.47
31
209
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
7
14
5.51
2.82
1.3
1.2
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
9
24
4.23
2.81
1.4
1.4
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
22
113
2.51
2.72
2.9
2.3
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
29
175
2.29
2.47
2.2
1.8
pmol/l
86.7
101.6
0.81
14
80
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
9
28
3.60
2.43
1.6
1.4
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
9
28
3.60
2.43
1.2
1.2
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
42
301
2.37
2.32
6.9
3.8
—
106.0
—
0
7
(3013650) Neutrophils [#/volume] in Blood by Automated count
39
273
2.26
2.25
6.2
10.0
e9/l
4.3
4.0
0.33
32
239
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
26
156
2.19
2.19
2.8
2.6
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
19
100
2.33
2.17
1.5
1.5
mg/l
0.8
1.0
0.56
14
75
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
15
79
2.21
1.68
2.1
3.2
ng/l
13.1
183.7
—
9
60
(3022621) pH of Urine by Test strip
7
26
2.91
1.64
3.1
2.4
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
10
44
2.53
1.63
2.0
1.4
—
—
—
0
0
(3014111) Lactate [Moles/volume] in Serum or Plasma
6
20
3.22
1.62
5.0
3.8
mmol/l
1.4
1.2
—
6
20
(3021589) Normoblasts [#/volume] in Blood
30
207
1.91
1.62
5.2
8.6
e9/l
0.0
0.0
0.00
24
169
(3045414) Leukocytes [Presence] in Urine
5
15
3.54
1.55
3.2
1.3
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
5
15
3.54
1.55
4.4
3.2
mmol/l
25.0
25.1
—
5
15
(3000330) Specific gravity of Urine by Test strip
6
21
3.06
1.55
4.0
4.7
—
—
—
0
0
(3000991) Gas panel - Venous blood
6
21
3.06
1.55
5.0
3.9
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
22
139
1.93
1.52
4.8
2.7
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
31
220
1.86
1.51
4.9
4.9
%
2.9
2.7
0.23
26
210
(3037467) Urinalysis macro (dipstick) panel - Urine
42
329
1.96
1.50
4.7
3.6
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
6
22
2.92
1.47
1.2
1.1
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
47
385
2.09
1.44
4.6
4.1
pmol/l
14.9
15.0
0.08
40
345
(3018010) Neutrophils/100 leukocytes in Blood
31
224
1.81
1.39
4.8
5.1
%
57.7
56.8
0.18
26
215
(3023368) Bacteria identified in Blood by Culture
17
101
1.96
1.39
4.2
3.2
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
5
17
3.11
1.39
5.8
4.5
%
95.7
94.8
—
5
17
(3044640) Blood type and Crossmatch panel - Blood
22
143
1.86
1.38
3.0
1.9
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
24
161
1.83
1.36
2.9
2.8
e6/l
10.7
90.1
1.71
19
106
(3002030) Lymphocytes/100 leukocytes in Blood
31
229
1.75
1.25
4.9
5.2
%
28.6
28.4
0.04
26
220
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
5
19
2.78
1.24
1.0
1.0
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
11
58
2.10
1.21
1.6
2.0
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
7
33
2.27
1.10
2.6
2.2
—
20.6
—
0
5
(3000494) Fungus identified in Specimen by Culture
10
53
2.07
1.09
1.2
1.4
—
—
—
0
0
(3012095) Magnesium [Moles/volume] in Serum or Plasma
12
69
1.93
1.06
2.1
2.8
mmol/l
0.9
0.8
0.55
12
63
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
16
103
1.76
1.01
3.2
1.7
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
24
174
1.64
0.99
3.9
3.9
—
—
—
0
0
(40761535) Cells panel - Urine sediment
6
27
2.36
0.96
4.2
4.4
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
22
158
1.63
0.93
5.3
4.2
—
—
—
0
0
(40758558) Short blood count panel - Blood
17
117
1.64
0.84
4.5
6.3
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
20
144
1.59
0.83
2.0
2.2
u/l
64.7
58.3
0.36
20
132
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
6
33
1.91
0.81
2.7
1.8
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
0
27
0.00
0.79
0.0
1.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
14
93
1.66
0.78
4.0
3.3
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
7
38
1.95
0.77
2.9
1.5
nmol/l
343.7
400.9
—
7
33
(4010399)
7
39
1.90
0.76
1.7
1.4
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
10
64
1.68
0.63
1.4
1.4
—
384.0
—
0
15
(3012516) Albumin [Mass/volume] in Urine
18
134
1.49
0.63
2.7
2.8
mg/l
3679.6
39.2
0.47
12
83
(3003694) ABO and Rh group [Type] in Blood
10
146
0.62
0.62
1.4
1.4
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
23
181
1.44
0.61
5.0
8.7
inr
1.2
1.2
—
7
63
(3041096) Erythrocytes [Presence] in Urine by Automated
18
135
1.48
0.61
5.1
3.4
—
—
—
0
0
(3022948) Iron [Moles/volume] in Serum or Plasma
10
65
1.65
0.60
1.4
1.7
umol/l
13.8
13.5
—
10
58
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
6
37
1.69
0.57
2.8
1.9
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
16
205
0.70
0.52
3.3
3.0
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
18
139
1.42
0.52
2.8
2.7
mmol/l
8.4
8.2
0.07
13
117
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
12
87
1.48
0.47
1.3
1.5
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
18
143
1.37
0.44
3.6
3.4
mg/mmol
0.8
5.8
—
10
89
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
8
58
1.44
0.44
4.8
7.1
—
—
—
0
0
(3012544) pH of Venous blood
5
33
1.56
0.42
1.2
2.7
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
15
0.00
0.42
0.0
1.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
26
221
1.32
0.41
3.8
3.5
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
6
42
1.48
0.37
1.7
1.7
—
—
—
0
0
(3044889) 12 lead EKG panel
39
357
1.27
0.32
3.7
3.4
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
8
65
1.27
0.28
1.6
1.7
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
21
182
1.24
0.26
4.3
3.9
ng/l
10.5
49.5
1.32
11
116
(40761536) Microorganisms panel - Urine sediment
5
41
1.24
0.22
5.6
3.6
—
—
—
0
0
(3027801) Oxygen [Partial pressure] in Arterial blood
5
42
1.21
0.22
7.8
5.7
kpa
12.4
11.9
—
5
42
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
5
42
1.21
0.22
7.8
5.7
kpa
4.9
5.0
—
5
42
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.2
—
247.0
—
0
5
(40768795) Lymph node Pathology biopsy report
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay
0
10
0.00
0.21
0.0
6.9
—
50.8
—
0
10
(3000764) Benzodiazepines [Presence] in Urine
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
(3050449) Albumin [Mass/time] in Urine collected for unspecified duration
0
14
0.00
0.20
0.0
2.6
—
54.1
—
0
7
(3003458) Phosphate [Moles/volume] in Serum or Plasma
7
57
1.26
0.19
2.3
3.1
mmol/l
1.0
1.1
—
7
51
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
9
80
1.15
0.16
1.7
1.4
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
13
112
1.21
0.16
3.3
5.6
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
49
472
1.23
0.16
18.1
11.4
%
38.6
40.3
0.73
35
350
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
52
503
1.28
0.16
4.9
4.3
mmol/l
1.5
1.5
0.18
45
454
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
33
311
1.14
0.13
2.5
2.7
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
11
96
1.18
0.11
1.2
1.2
u/ml
0.4
0.6
—
5
26
(3000492) Spirometry study
5
43
1.18
0.10
1.0
1.5
—
—
—
0
0
(3019225) pH of Specimen
5
44
1.15
0.10
5.0
4.1
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
5
47
1.07
0.09
7.8
5.8
mmol/l
0.3
1.9
—
5
38
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
53
517
1.25
0.08
5.3
4.8
mmol/l
2.8
2.8
0.02
47
469
(46235355) HIV 1 and 2 tests - Meaningful Use set
8
73
1.11
0.08
1.8
1.8
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
52
508
1.20
0.07
5.0
4.3
mmol/l
4.7
4.7
0.17
45
464
(40768804) Tissue Pathology biopsy report
23
220
1.07
0.04
2.3
2.0
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
49
484
1.07
0.01
4.3
3.9
mmol/l
1.3
1.3
0.03
42
434
(3013512) EKG study
14
146
0.95
0.01
3.2
3.6
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035880) pH of Pleural fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(4146454)
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
0.8
—
0
5
(3018301) Testosterone Free [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
6
0.00
0.00
0.0
1.7
—
13.2
—
0
6
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
9.4
—
2318.2
—
0
5
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
5
52
0.96
0.00
2.4
3.2
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
8
0.00
0.00
0.0
4.0
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
7
72
0.97
0.00
1.9
1.7
nmol/l
783.4
1151.2
—
7
51
(3005570) Glucose [Moles/volume] in Urine
0
6
0.00
0.00
0.0
3.8
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
6.8
—
1080.0
—
0
5
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
5
0.00
0.00
0.0
2.6
—
31.2
—
0
5
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(4268621)
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
9
0.00
0.00
0.0
3.0
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
(3002256) Pathology report gross observation
7
72
0.97
0.00
1.1
1.2
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3022145) Colonoscopy Study observation
6
59
1.02
0.00
1.2
1.4
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3010838) Calcium [Moles/time] in 24 hour Urine
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
8
0.00
0.00
0.0
4.0
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
7.2
—
61.9
—
0
5
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(4306422)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_SPINEFUSION and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_SPINEFUSION.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: M13_SPINEFUSION – Other fusion of spine

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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