Congenital glaucoma

Q17_CONGEN_GLAUC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Q15.0 Cause of death: ICD-10 — Q15.0 2 out of 7 registries used, show all original rules.	43
4. Check minimum number of events None	43
5. Include endpoints None	43
6. Filter based on genotype QC (FinnGen only)	43

Control definitions (FinnGen only)

Control exclude: Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF6v3

NAME	Q17_CONGEN_GLAUC
CONTROL_EXCLUDE	Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q150
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q150
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Congenital glaucoma based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	427	189	235
Only index persons	351	158	193
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	20.21	29.94	11.72
Only index persons	23.28	30.94	17.01

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	43	22	21
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	44.94	43.80	46.13

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3044889) 12 lead EKG panel

213

2.63

2.11

3.9

3.6

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.74

1.89

2.0

2.4

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.48

1.85

3.4

2.8

0.1

0.9

e6/l

—

(3007461) Platelets [#/volume] in Blood

382

+∞

1.84

21.9

22.4

238.3

250.9

e9/l

0.64

372

(3026361) Erythrocytes [#/volume] in Blood

382

+∞

1.84

21.9

22.4

4.5

e12/l

0.10

368

(3010813) Leukocytes [#/volume] in Blood

382

+∞

1.84

21.9

22.5

6.5

6.8

e9/l

0.28

369

(3024731) MCV [Entitic volume]

382

+∞

1.84

21.9

22.3

88.6

89.4

0.38

374

(3000963) Hemoglobin [Mass/volume] in Blood

382

+∞

1.84

21.9

22.5

131.0

133.3

g/l

0.47

374

(3035941) MCH [Entitic mass]

382

+∞

1.84

21.9

22.3

29.4

29.8

0.66

374

(40758558) Short blood count panel - Blood

103

2.29

1.76

4.6

7.0

—

(3003338) MCHC [Mass/volume]

295

2.82

1.66

19.1

19.4

331.4

333.4

g/l

0.61

295

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.39

1.65

3.5

3.1

7.1

2.4

e6/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

137

2.04

1.43

5.8

3.5

—

(36304419) Bacteria [Presence] in Urine

115

1.97

1.27

5.8

3.0

—

(3026008) Bacteria identified in Urine by Culture

100

1.96

1.18

2.3

2.6

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

154

1.88

1.16

8.5

9.7

1.2

mmol/l

0.54

146

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

293

2.04

1.08

13.7

13.8

81.9

82.8

ml/min/173m2

0.07

232

(3009542) Hematocrit [Volume Fraction] of Blood

329

2.33

1.07

16.8

37.6

39.4

0.62

250

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.19

1.05

3.0

3.7

—

(42870588) Differential panel, method unspecified - Blood

131

1.81

1.02

5.9

6.5

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.88

1.00

3.8

3.3

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

250

1.86

0.97

7.0

7.8

87.3

92.3

u/l

0.17

238

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

1.89

0.94

2.8

1.7

1.2

1.3

mmol/l

0.35

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

117

1.75

0.90

5.0

3.8

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

118

1.73

0.87

2.1

1.8

77.2

91.8

pmol/l

—

(3023368) Bacteria identified in Blood by Culture

110

1.72

0.84

2.8

5.0

—

(3042936) Bacteria identified in Isolate by Culture

1.80

0.80

2.2

2.3

—

(40768804) Tissue Pathology biopsy report

115

1.62

0.70

1.6

2.1

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.62

0.0

1.8

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

0.61

0.0

1.6

—

(3019225) pH of Specimen

0.00

0.60

0.0

8.9

—

(40768797) Stomach Pathology biopsy report

1.77

0.59

1.0

1.2

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

112

1.52

0.54

4.1

3.2

2.4

mmol/l

0.62

(3013512) EKG study

1.53

0.49

1.4

5.1

—

(3037467) Urinalysis macro (dipstick) panel - Urine

231

1.45

0.48

5.5

4.6

—

(3019309) Folate [Moles/volume] in Red Blood Cells

1.52

0.46

1.8

1393.8

1200.0

nmol/l

—

(3006504) Eosinophils/100 leukocytes in Blood

174

1.40

0.43

6.5

3.8

3.0

0.92

163

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.42

0.0

1.3

—

(3018010) Neutrophils/100 leukocytes in Blood

175

1.39

0.42

7.8

6.4

53.6

54.4

0.07

166

(3019069) Monocytes/100 leukocytes in Blood

175

1.39

0.42

6.5

6.6

9.4

8.5

0.66

165

(3001122) Ferritin [Mass/volume] in Serum or Plasma

146

1.40

0.42

3.1

2.8

138.0

90.7

ug/l

0.43

138

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.41

0.0

1.3

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.41

0.0

1.3

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.41

0.0

1.3

—

(3026493) Urate [Moles/volume] in Serum or Plasma

0.61

0.40

1.4

3.7

346.2

360.1

umol/l

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.44

0.39

1.2

1.7

—

(3002030) Lymphocytes/100 leukocytes in Blood

178

1.35

0.36

6.5

6.6

29.3

29.8

0.04

167

(1761868) Lipid panel - Serum or Plasma

107

0.69

0.34

3.6

2.8

—

(3000494) Fungus identified in Specimen by Culture

1.44

0.34

1.4

1.2

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

1.38

0.32

3.6

4.8

1.2

2.2

ug/l

0.75

(3015736) pH of Urine

132

1.34

0.32

4.4

3.4

—

(3022096) Basophils/100 leukocytes in Blood

171

1.32

0.31

6.8

6.5

0.8

0.7

1.03

161

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.28

0.29

1.0

2.1

—

(3003694) ABO and Rh group [Type] in Blood

1.36

0.28

1.5

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

295

1.33

0.27

4.7

4.2

1.4

mmol/l

0.09

261

(36660697) Celiac disease serology panel - Serum

1.28

0.23

1.0

1.2

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.25

0.23

2.2

1.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.32

0.21

1.0

2.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.32

0.21

1.0

2.0

—

(44790048)

0.00

0.21

0.0

2.1

—

(44790047)

0.00

0.21

0.0

2.1

—

(44806118)

0.00

0.21

0.0

2.1

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

0.21

0.0

3.4

—

3.8

—

(3006184) Hemoglobin [Mass/volume] in Capillary blood

0.00

0.21

0.0

2.4

—

113.2

—

(44790049)

0.00

0.21

0.0

2.1

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.2

—

17.1

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.1

—

322.5

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(40767503) Oxygen content in Capillary blood by calculation

0.00

0.21

0.0

2.6

—

13.7

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

0.3

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

0.21

0.0

1.6

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.2

—

(3008898) HLA-B27 [Presence]

0.00

0.21

0.0

1.0

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

0.21

0.0

3.5

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

1.1

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.20

0.19

2.3

1.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.20

0.19

2.1

1.8

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.18

0.19

5.4

10.2

0.7

0.8

mmol/l

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

0.71

0.18

1.8

1.7

433.8

494.6

pmol/l

—

(3021960) Folate [Moles/volume] in Serum or Plasma

1.20

0.18

1.5

1.4

24.4

21.4

nmol/l

—

(3032080) INR in Blood by Coagulation assay

131

1.22

0.17

10.5

8.2

1.3

1.2

inr

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.16

0.17

7.6

5.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.14

0.16

1.8

3.1

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

171

1.20

0.16

5.7

7.5

25.1

19.7

umol/l

0.16

165

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

304

1.21

0.13

5.3

4.6

2.6

2.7

mmol/l

0.31

271

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

286

0.85

0.13

5.4

5.7

37.6

39.5

mmol/mol

0.79

261

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

305

1.19

0.12

4.0

4.4

1.7

2.0

mu/l

0.97

271

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.15

0.10

1.2

1.4

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.07

0.10

9.6

13.8

25.2

24.7

mmol/l

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.13

0.09

12.7

9.0

1.0

1.2

mmol/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.07

0.07

6.2

3.2

—

(3044640) Blood type and Crossmatch panel - Blood

109

1.14

0.07

1.9

3.1

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

251

0.90

0.06

3.8

3.9

14.7

pmol/l

0.03

229

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

134

1.07

0.01

3.1

3.7

32.9

44.6

ng/l

—

100

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

246

0.94

0.01

2.8

3.6

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

299

1.01

0.00

4.9

4.4

5.7

5.8

mmol/l

0.61

269

(3024561) Albumin [Mass/volume] in Serum or Plasma

151

0.99

0.00

6.3

5.0

37.4

35.9

g/l

0.39

142

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

1.05

0.00

3.7

2.6

71.2

55.9

u/l

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

286

1.04

0.00

4.0

3.8

1.1

1.2

mmol/l

0.39

251

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

142

0.98

0.00

4.9

4.5

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

1.4

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3034770) Mitochondria Ab [Titer] in Serum

0.00

0.0

1.9

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.0

1.3

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.0

1.3

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.3

—

88.7

—

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

0.00

0.0

1.0

—

168.3

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

175.0

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.3

—

(3027008) Opiates [Presence] in Urine

0.00

0.0

1.3

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.0

1.3

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

3.3

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.3

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.0

3.0

—

(3021788) Differential panel - Synovial fluid

0.00

0.0

1.2

—

(3016879) Cocaine [Presence] in Urine

0.00

0.0

1.3

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.0

1.3

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.0

1.8

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.4

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.4

—

(3020044) Glucose [Moles/volume] in Cerebral spinal fluid

0.00

0.0

1.1

—

3.9

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

154.2

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

1.5

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

1.0

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

6.8

—

78.2

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.0

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

(4094501)

0.00

0.0

1.2

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

77.7

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(4027681)

0.00

0.0

1.2

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.2

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.0

1.3

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.96

0.00

2.2

1.3

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

1.4

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.0

1.3

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.3

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.0

1.0

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.0

4.0

—

2.7

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

11.8

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

2.0

—

14.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

0.89

0.00

1.8

2.0

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.3

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.0

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.0

1.3

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.0

—

(40768800) Prostate Pathology biopsy report

0.00

0.0

1.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.2

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.3

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.1

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.5

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.0

1.0

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.2

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

0.0

5.3

—

7.2

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

12.4

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

4.2

—

148.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_CONGEN_GLAUC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_CONGEN_GLAUC.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: Q17_CONGEN_GLAUC – Congenital glaucoma

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Congenital glaucoma

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints