Crushing injury of lower leg

ST19_CRUSHI_INJURY_LOWER_LEG

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — S87 Cause of death: ICD-10 — S87 2 out of 7 registries used, show all original rules.	89
4. Check minimum number of events None	89
5. Include endpoints None	89
6. Filter based on genotype QC (FinnGen only)	89

Control definitions (FinnGen only)

Control exclude: ST19_INJURI_KNEE_LOWER_LEG

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: S8
Name in latin: Conquassatio genus/cruris

NAME	ST19_CRUSHI_INJURY_LOWER_LEG
CONTROL_EXCLUDE	ST19_INJURI_KNEE_LOWER_LEG
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	S87
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	S87
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Crushing injury of lower leg based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	89	39	50
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	48.44	48.70	48.23

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
80: Matched controls
801

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

S87.8

ICD-10 Finland

Crushing injury of other and unspecified parts of lower leg

+∞

66.0

S87.0

ICD-10 Finland

Crushing injury of knee

+∞

26.5

NHJ10

NOMESCO Finland

Internal fixation of fracture of ankle using wire, rod, cerclage or pin

+∞

18.4

S82.8

ICD-10 Finland

Fractures of other parts of lower leg

+∞

18.4

QDB05

NOMESCO Finland

Revision of wound of skin of lower limb

27.1

14.1

NGJ70

NOMESCO Finland

External fixation of fracture of knee or lower leg, other or unspecified

+∞

11.7

QDE35

NOMESCO Finland

Repair of skin defect in lower limb after surgery or injury

+∞

10.6

NGU20

NOMESCO Finland

Removal of internal fixation device from knee or lower leg

112.7

9.6

ZZA00

NOMESCO Finland

Split skin graft

18.5

9.4

X58

ICD-10 Finland

Exposure to other specified factors

7.8

9.3

S80.1

ICD-10 Finland

Contusion of other and unspecified parts of lower leg

41.8

9.3

W31

ICD-10 Finland

Contact with other and unspecified machinery

31.4

8.7

S82.3

ICD-10 Finland

Fracture of lower end of tibia

+∞

8.5

S82.2

ICD-10 Finland

Fracture of shaft of tibia

+∞

8.5

ZXA00

NOMESCO Finland

Right side

4.5

8.4

123

M17.3

ICD-10 Finland

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3042936) Bacteria identified in Isolate by Culture

2.85

4.07

2.0

1.7

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

112

2.56

3.46

1.3

32.8

35.8

iu/ml

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.72

3.14

1.2

1.6

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

7.94

3.10

1.7

2.0

—

(3020891) Body temperature

4.23

2.86

4.2

4.0

—

(3023368) Bacteria identified in Blood by Culture

194

2.11

2.75

5.2

4.4

—

(3011288) Drugs identified in Urine by Screen method

3.88

2.66

2.0

1.5

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

3.46

2.38

1.6

1.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

3.00

2.28

1.6

1.3

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

142

2.06

2.23

2.6

2.5

—

(3028707) Methadone [Presence] in Urine by Screen method

3.90

2.20

1.7

1.4

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

159

2.00

2.18

1.8

1.7

0.9

1.1

mg/l

0.35

134

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

105

2.17

1.5

1.3

4.0

15.7

u/ml

—

(3016879) Cocaine [Presence] in Urine

3.11

2.14

1.6

1.4

—

(3021589) Normoblasts [#/volume] in Blood

304

1.80

1.96

11.1

8.7

0.0

e9/l

0.08

252

(3011397) Hemoglobin [Presence] in Urine by Test strip

157

1.93

1.94

4.1

3.6

—

(3027008) Opiates [Presence] in Urine

2.66

1.80

1.7

1.4

—

(3028300) Cannabinoids [Presence] in Urine

2.66

1.80

1.7

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

2.66

1.80

1.7

1.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.21

1.64

1.7

1.6

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.05

1.56

8.3

8.5

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

320

1.67

1.54

7.7

6.3

1.2

mmol/l

0.20

272

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

2.99

1.53

1.2

1.1

0.3

g/l

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.52

1.51

1.2

1.1

—

(3019150) Specific gravity of Urine by Refractometry

161

1.77

1.50

4.3

4.4

1.0

kg/l

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

2.85

1.46

1.2

1.1

1.3

1.2

g/l

—

(3044889) 12 lead EKG panel

474

1.64

1.38

4.2

3.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.04

1.37

1.7

1.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

100

1.87

1.35

1.5

1.9

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.88

1.30

1.6

—

(3027944) Amphetamines [Presence] in Urine

2.34

1.28

1.7

1.4

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.27

1.25

1.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.27

1.25

3.8

6.8

25.8

24.5

mmol/l

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.72

1.23

1.4

—

(3044640) Blood type and Crossmatch panel - Blood

205

1.62

1.22

3.0

2.4

—

(40761535) Cells panel - Urine sediment

2.13

1.22

4.2

3.8

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

112

1.76

1.20

1.4

1.6

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.59

1.16

1.2

1.1

—

(3019060) Gas panel - Arterial blood

2.11

1.09

2.8

4.0

—

(3000991) Gas panel - Venous blood

2.02

1.06

3.9

8.7

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.92

1.04

1.5

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

232

1.52

1.01

2.7

3.2

2.3

mmol/l

0.51

207

(40768443) Skin Pathology biopsy report

0.00

0.99

0.0

1.1

—

(3000494) Fungus identified in Specimen by Culture

1.78

0.98

1.7

1.3

—

(3018095) Leukocytes [#/volume] in Urine

254

1.48

0.93

3.7

3.2

131.3

149.0

e6/l

0.04

170

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

682

1.63

0.88

16.3

13.0

85.2

83.0

ml/min/173m2

0.35

547

(3013650) Neutrophils [#/volume] in Blood by Automated count

401

1.43

0.87

11.9

10.1

4.0

4.2

e9/l

0.23

356

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.88

0.80

1.7

1.8

—

(3018418) pH of Serum or Plasma

197

1.45

0.78

3.3

3.7

7.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

235

1.42

0.75

3.6

3.0

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.06

0.74

1.2

—

(3021601) Nitrite [Presence] in Urine by Test strip

351

1.37

0.72

5.2

5.3

0.0

estimate

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

103

1.55

0.70

2.6

2.5

1.4

3.1

e6/l

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.62

0.70

1.9

2.2

—

(36304419) Bacteria [Presence] in Urine

183

1.43

0.69

2.9

2.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

296

1.36

0.67

4.4

4.1

—

(3035350) Ketones [Presence] in Urine by Test strip

354

1.35

0.67

3.8

0.0

estimate

—

(3037467) Urinalysis macro (dipstick) panel - Urine

463

1.36

0.67

4.0

4.1

—

(3001604) Monocytes [#/volume] in Blood

346

1.34

0.64

9.1

5.4

0.6

e9/l

0.08

309

(3022621) pH of Urine by Test strip

1.66

0.63

3.8

2.6

—

(3006315) Basophils [#/volume] in Blood

347

1.34

0.63

9.2

5.4

0.0

e9/l

0.04

309

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.71

0.62

1.2

2.0

26.4

152.0

ng/l

—

(3008898) HLA-B27 [Presence]

1.71

0.62

1.0

1.1

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

115

1.48

0.62

2.4

2.3

0.7

1.0

e6/l

—

(42870588) Differential panel, method unspecified - Blood

224

1.36

0.61

7.6

4.9

—

(3009261) Glucose [Presence] in Urine by Test strip

358

1.33

0.61

4.1

3.9

0.0

estimate

—

(21494755) Public health laboratory ask at order entry panel

0.54

0.60

1.6

1.3

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.53

0.59

4.4

3.4

1.2

mmol/l

—

(3002582) Erythrocytes [#/volume] in Urine

217

1.35

0.57

3.2

2.7

9.2

65.5

e6/l

1.53

159

(3019198) Lymphocytes [#/volume] in Blood

351

1.31

0.57

9.3

5.5

1.8

e9/l

0.08

317

(3041096) Erythrocytes [Presence] in Urine by Automated

211

0.71

0.56

3.1

3.5

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

700

0.74

0.56

4.8

4.3

4.7

4.6

mmol/l

0.13

642

(1761868) Lipid panel - Serum or Plasma

284

0.74

0.54

2.7

2.9

—

(3003694) ABO and Rh group [Type] in Blood

185

0.71

0.49

1.7

1.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

467

1.27

0.47

2.8

3.0

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.46

0.47

2.1

2.3

—

(3013115) Eosinophils [#/volume] in Blood

358

1.27

0.47

9.4

5.9

0.2

e9/l

0.48

321

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

676

0.77

0.47

4.6

3.9

1.4

mmol/l

0.14

621

(4010399)

1.50

0.44

1.4

—

(3045414) Leukocytes [Presence] in Urine

1.54

0.42

3.2

1.8

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

227

1.27

0.41

2.6

2.4

64.1

53.5

u/l

0.51

214

(40768800) Prostate Pathology biopsy report

0.00

0.41

0.0

1.1

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

237

1.26

0.40

3.8

3.1

569.5

33.0

u/l

0.49

228

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.40

0.0

1.4

—

(3019225) pH of Specimen

1.38

0.39

5.6

4.6

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.41

0.39

3.2

2.6

131.4

128.4

g/l

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

699

0.78

0.38

4.6

4.3

1.4

mmol/l

0.51

642

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.37

0.38

1.8

1.6

—

(40758558) Short blood count panel - Blood

173

1.28

0.37

9.9

6.9

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.42

0.36

2.7

2.6

0.0

0.1

e6/l

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.36

0.34

1.3

2.1

—

(40761511) CBC panel - Blood by Automated count

759

1.36

0.33

16.9

12.0

—

(3012544) pH of Venous blood

1.40

0.32

2.3

3.2

—

(3015736) pH of Urine

282

1.21

0.32

3.4

3.7

—

(3026008) Bacteria identified in Urine by Culture

187

1.23

0.30

3.5

3.1

—

(3000492) Spirometry study

1.32

0.27

1.4

1.3

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

278

1.18

0.25

4.4

14.5

1.9

ug/l

0.46

249

(3022313) Gas panel - Capillary blood

1.37

0.24

3.2

3.1

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.33

0.23

1.2

1.9

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

280

1.16

0.23

4.8

3.4

58.0

39.5

ng/l

0.21

193

(3032080) INR in Blood by Coagulation assay

281

1.16

0.21

6.7

8.7

1.0

1.2

inr

3.43

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.21

0.0

3.2

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.2

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

2.9

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.9

—

4.9

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

2.9

—

4.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.2

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.2

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

2.9

—

107.5

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

14.1

—

(40768795) Lymph node Pathology biopsy report

0.00

0.21

0.0

1.4

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.3

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

6.2

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.1

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.21

0.0

1.1

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.21

0.0

4.5

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

1.1

—

(3030467) Casts [#/volume] in Urine by Automated count

194

1.18

0.21

3.3

2.6

0.0

0.3

e6/l

2.24

137

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.2

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.2

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

715

0.84

0.21

5.2

4.7

2.8

mmol/l

0.01

658

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

1.24

0.20

6.0

3.0

1.7

2.0

mmol/l

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.20

0.0

1.5

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.20

0.0

1.4

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.20

0.0

1.1

—

(4035726)

1.20

0.18

1.4

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.14

0.18

1.9

1.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

140

1.17

0.16

1.8

2.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

273

0.88

0.15

2.8

1.7

94.8

95.1

pmol/l

0.01

141

(3025941) Bacteria identified in Stool by Culture

1.12

0.10

1.4

1.2

—

(3029937) Albumin [Presence] in Urine by Test strip

204

1.10

0.10

5.0

3.9

0.0

estimate

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.07

0.09

1.0

—

(3007164) IgA [Mass/volume] in Serum or Plasma

146

1.12

0.09

1.3

2.5

2.4

g/l

—

(3002256) Pathology report gross observation

1.14

0.07

1.3

1.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

649

1.07

0.05

18.0

13.5

40.8

40.6

0.14

506

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

281

0.94

0.04

4.5

4.0

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

121

1.09

0.04

1.7

1.5

—

(40768797) Stomach Pathology biopsy report

1.08

0.02

1.3

1.2

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

634

1.03

0.00

4.4

4.3

1.9

mu/l

0.02

578

(3013512) EKG study

198

1.01

0.00

3.8

4.0

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

1.03

0.00

1.9

1.5

1.6

—

(40768804) Tissue Pathology biopsy report

281

0.99

0.00

2.5

2.0

—

(40760892) CBC W Ordered Manual Differential panel - Blood

155

0.96

0.00

4.5

5.2

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

105

1.05

0.00

1.5

1.8

2.5

2.4

g/l

0.70

(3022948) Iron [Moles/volume] in Serum or Plasma

116

1.04

0.00

1.6

1.8

17.2

12.6

umol/l

0.67

105

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.0

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

0.0

3.3

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

2.4

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

11.3

—

2710.4

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.7

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

9.9

—

1199.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

137.5

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

2.8

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.0

1.9

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.97

0.00

1.4

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

1665.2

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.0

1.7

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

0.0

1.5

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.89

0.00

2.0

1.5

—

(36660697) Celiac disease serology panel - Serum

0.89

0.00

1.4

1.2

—

(44813793)

0.00

0.0

1.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

220

1.00

0.00

4.5

4.2

28.6

22.2

—

104

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(44806420)

0.00

0.0

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.88

0.00

8.6

3.7

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

0.0

1.0

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.4

—

(3014271) Vancomycin [Susceptibility]

0.00

0.0

1.8

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.0

—

(3020650) Glucose [Presence] in Urine

0.00

0.0

1.2

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

3.3

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.98

0.00

1.4

1.8

322.4

359.7

nmol/l

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

3.0

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_CRUSHI_INJURY_LOWER_LEG – Crushing injury of lower leg

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Crushing injury of lower leg

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Crushing injury of lower leg (ST19_CRUSHI_INJURY_LOWER_LEG)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints