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This is a non-core endpoint: only basic statistics are computed.

Crushing injury of lower leg

ST19_CRUSHI_INJURY_LOWER_LEG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 S87
  • Cause of death: ICD-10 S87

2 out of 7 registries used, show all original rules.

89

4. Check minimum number of events

None

89

5. Include endpoints

None

89

6. Filter based on genotype QC (FinnGen only)

89

Control definitions (FinnGen only)

Control exclude
ST19_INJURI_KNEE_LOWER_LEG

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S8
Name in latin
Conquassatio genus/cruris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 89 39 50
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 48.44 48.70 48.23

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
80
Matched controls
801
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S87.8
ICD-10 Finland
Crushing injury of other and unspecified parts of lower leg
+∞
66.0
54
*
S87.0
ICD-10 Finland
Crushing injury of knee
+∞
26.5
24
*
NHJ10
NOMESCO Finland
Internal fixation of fracture of ankle using wire, rod, cerclage or pin
+∞
18.4
17
*
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
+∞
18.4
17
*
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
27.1
14.1
19
9
NGJ70
NOMESCO Finland
External fixation of fracture of knee or lower leg, other or unspecified
+∞
11.7
11
*
QDE35
NOMESCO Finland
Repair of skin defect in lower limb after surgery or injury
+∞
10.6
10
*
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
112.7
9.6
10
*
ZZA00
NOMESCO Finland
Split skin graft
18.5
9.4
14
9
X58
ICD-10 Finland
Exposure to other specified factors
7.8
9.3
22
37
S80.1
ICD-10 Finland
Contusion of other and unspecified parts of lower leg
41.8
9.3
11
*
W31
ICD-10 Finland
Contact with other and unspecified machinery
31.4
8.7
11
*
ZXE10
NOMESCO Finland
More than one and less than three hours
4.3
8.6
44
176
S82.3
ICD-10 Finland
Fracture of lower end of tibia
+∞
8.5
8
*
S82.2
ICD-10 Finland
Fracture of shaft of tibia
+∞
8.5
8
*
ZXA00
NOMESCO Finland
Right side
4.5
8.4
36
123
ZXD05
NOMESCO Finland
Urgent procedure
4.3
8.3
38
138
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
37.5
8.3
10
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
4.5
8.3
35
118
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
15.2
8.2
13
10
S80.0
ICD-10 Finland
Contusion of knee
11.8
7.9
14
14
NG4AA
NOMESCO Finland
Lower leg X-ray examination
28.1
7.8
10
*
NGU10
NOMESCO Finland
Removal of external fixation device from knee or lower leg
+∞
7.4
7
*
NGQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of knee or lower leg
+∞
7.4
7
*
T93.6
ICD-10 Finland
Sequelae of crushing injury and traumatic amputation of lower limb
+∞
7.4
7
*
X59
ICD-10 Finland
Exposure to unspecified factor
5.2
7.2
23
57
Z2446
NOMESCO Finland
Social worker
7.7
7.1
16
25
B01AB05
ATC
enoxaparin; parenteral
3.8
6.8
35
136
Z3226
NOMESCO Finland
Physiotherapist
4.9
6.7
23
61
N02AX02
ATC
tramadol; systemic, rectal
3.5
6.7
42
190
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
12.5
6.5
11
10
NGJ62
NOMESCO Finland
Internal fixation of fracture of knee or lower leg using plate and screws, other or unspecified
+∞
6.3
6
*
S82.1
ICD-10 Finland
Fracture of upper end of tibia
+∞
6.3
6
*
N03AX16
ATC
pregabalin; oral
4.0
6.2
27
90

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_CRUSHI_INJURY_LOWER_LEG – Crushing injury of lower leg

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).