Crushing injury of lower leg

ST19_CRUSHI_INJURY_LOWER_LEG

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — S87 Cause of death: ICD-10 — S87 2 out of 7 registries used, show all original rules.	93
4. Check minimum number of events None	93
5. Include endpoints None	93
6. Filter based on genotype QC (FinnGen only)	92

Control definitions (FinnGen only)

Control exclude: ST19_INJURI_KNEE_LOWER_LEG

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: S8
Name in latin: Conquassatio genus/cruris

NAME	ST19_CRUSHI_INJURY_LOWER_LEG
CONTROL_EXCLUDE	ST19_INJURI_KNEE_LOWER_LEG
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	S87
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	S87
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Crushing injury of lower leg based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	92	41	51
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	48.95	48.47	49.34

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
93: Matched controls
930

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

S87.8

ICD-10 Finland

Crushing injury of other and unspecified parts of lower leg

+∞

77.1

S87.0

ICD-10 Finland

Crushing injury of knee

+∞

29.8

S82.8

ICD-10 Finland

Fractures of other parts of lower leg

+∞

20.6

NHJ10

NOMESCO Finland

Internal fixation of fracture of ankle using wire, rod, cerclage or pin

220.2

18.2

QDB05

NOMESCO Finland

Revision of wound of skin of lower limb

47.0

16.1

NGJ70

NOMESCO Finland

External fixation of fracture of knee or lower leg, other or unspecified

+∞

13.9

X58

ICD-10 Finland

Exposure to other specified factors

6.4

13.7

S80.1

ICD-10 Finland

Contusion of other and unspecified parts of lower leg

136.2

11.7

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

4.5

11.1

134

ZZA00

NOMESCO Finland

Split skin graft

22.0

10.7

QDE35

NOMESCO Finland

Repair of skin defect in lower limb after surgery or injury

123.3

10.7

NGU20

NOMESCO Finland

Removal of internal fixation device from knee or lower leg

123.3

10.7

TNX33

NOMESCO Finland

Custom moulded cast, unspecified region

14.7

8.7

NG4AA

NOMESCO Finland

Lower leg X-ray examination

30.8

8.7

QDB10

NOMESCO Finland

Major dressing of wound of skin of lower limb

11.1

8.7

S82.2

ICD-10 Finland

Fracture of shaft of tibia

+∞

8.5

S82.3

ICD-10 Finland

Fracture of lower end of tibia

+∞

8.5

ZXE10

NOMESCO Finland

More than one and less than three hours

3.6

8.4

214

X59

ICD-10 Finland

Exposure to unspecified factor

4.1

8.2

ZXD05

NOMESCO Finland

Urgent procedure

3.5

8.1

183

T93.2

ICD-10 Finland

Sequelae of other fractures of lower limb

49.3

7.9

ZXA00

NOMESCO Finland

Right side

3.6

7.9

145

S83.6

ICD-10 Finland

Sprain and strain of other and unspecified parts of knee

27.7

7.7

NGQ48

NOMESCO Finland

Revision of exarticulation or amputation stump of knee or lower leg

+∞

7.4

NGU10

NOMESCO Finland

Removal of external fixation device from knee or lower leg

+∞

7.4

S80.0

ICD-10 Finland

Contusion of knee

7.5

7.4

V49.9

ICD-10 Finland

Car occupant [any] injured in unspecified traffic accident

13.6

7.3

M17.3

ICD-10 Finland

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3042936) Bacteria identified in Isolate by Culture

103

2.64

3.59

2.0

1.7

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

119

2.51

3.44

1.3

30.33

35.15

iu/ml

0.08

(3023368) Bacteria identified in Blood by Culture

201

2.19

3.12

5.5

4.4

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

7.92

3.10

1.7

2.0

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.59

2.90

1.2

1.6

—

(3020891) Body temperature

4.04

2.75

4.2

3.9

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

145

2.10

2.43

3.0

2.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.52

2.39

1.9

1.6

—

(3011288) Drugs identified in Urine by Screen method

3.32

2.29

2.0

1.4

—

(3021589) Normoblasts [#/volume] in Blood

322

1.85

2.20

12.0

8.1

0.00

e9/l

0.08

267

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

333

1.83

2.15

7.4

6.2

1.20

mmol/l

0.14

287

(1001926) Buprenorphine [Presence] in Urine by Screen method

3.10

2.14

1.6

1.4

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.25

2.12

3.6

6.2

104.53

104.67

mmol/l

0.03

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

5.21

2.10

1.2

1.1

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

161

1.95

2.08

1.8

1.7

0.86

1.06

mg/l

0.33

134

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.33

2.05

1.9

1.6

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.75

2.01

1.6

1.3

—

(3028707) Methadone [Presence] in Urine by Screen method

3.52

2.01

1.7

1.4

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

116

2.05

1.99

1.5

1.3

3.70

14.06

u/ml

—

(3016879) Cocaine [Presence] in Urine

2.82

1.92

1.6

1.4

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

103

2.06

1.89

1.7

2.0

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

163

1.83

1.70

4.1

3.6

—

(3044889) 12 lead EKG panel

498

1.73

1.68

4.1

3.6

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

3.71

1.63

1.2

1.1

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

3.46

1.54

1.6

1.5

—

(3044640) Blood type and Crossmatch panel - Blood

211

1.70

1.53

3.2

2.4

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.51

1.50

3.4

6.7

25.90

24.60

mmol/l

—

(3028300) Cannabinoids [Presence] in Urine

2.44

1.48

1.7

1.4

—

(3027008) Opiates [Presence] in Urine

2.44

1.48

1.7

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

2.44

1.48

1.7

1.4

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.32

1.41

1.2

1.1

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.06

1.41

1.5

1.6

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

2.72

1.39

1.2

1.1

0.32

0.25

g/l

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.94

1.37

8.3

—

(3000991) Gas panel - Venous blood

2.21

1.33

4.1

8.6

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

2.60

1.32

1.2

1.1

1.29

1.27

g/l

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.87

1.30

1.6

1.5

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

2.87

1.30

1.2

1.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

126

1.75

1.28

1.4

1.7

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

2.33

1.28

2.5

9.4

22.29

24.30

mmol/l

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

420

1.54

1.22

12.4

10.0

3.92

4.22

e9/l

0.37

374

(3018418) pH of Serum or Plasma

205

1.60

1.21

3.4

3.5

7.41

7.40

—

(3019150) Specific gravity of Urine by Refractometry

171

1.63

1.19

4.3

1.02

kg/l

—

(3027944) Amphetamines [Presence] in Urine

2.15

1.18

1.8

1.4

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.58

1.16

1.4

—

(40761535) Cells panel - Urine sediment

2.08

1.16

4.1

3.9

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.04

1.12

1.3

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.46

1.10

1.2

1.1

—

(3019060) Gas panel - Arterial blood

2.01

1.06

2.8

4.0

—

(3018095) Leukocytes [#/volume] in Urine

266

1.51

1.05

3.6

3.2

125.17

141.38

e6/l

0.04

180

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

713

1.72

1.04

17.0

12.7

85.71

83.73

ml/min/173m2

0.32

575

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.08

1.02

2.1

1.8

—

(40768443) Skin Pathology biopsy report

0.00

0.99

0.0

1.1

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

243

1.48

0.96

2.6

3.2

2.33

2.35

mmol/l

0.50

220

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

310

1.44

0.92

3.1

2.5

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

2.07

0.88

1.2

2.0

42.17

152.04

ng/l

—

(36304419) Bacteria [Presence] in Urine

192

1.49

0.88

2.9

2.5

—

(3000494) Fungus identified in Specimen by Culture

1.70

0.86

1.7

1.2

—

(3001604) Monocytes [#/volume] in Blood

364

1.40

0.81

9.3

5.2

0.64

0.58

e9/l

0.40

327

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

251

1.42

0.79

3.4

2.9

—

(3006315) Basophils [#/volume] in Blood

365

1.39

0.79

9.4

5.2

0.04

e9/l

0.21

327

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

2.24

0.77

1.2

1.6

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

2.24

0.77

1.2

1.6

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.70

0.76

4.0

3.1

1.23

1.22

mmol/l

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

111

1.53

0.72

2.7

2.4

1.37

3.40

e6/l

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.97

0.72

1.2

—

(3002582) Erythrocytes [#/volume] in Urine

229

1.39

0.69

3.1

2.7

9.19

62.63

e6/l

1.56

170

(3019198) Lymphocytes [#/volume] in Blood

372

1.35

0.68

9.5

5.3

3.89

1.84

e9/l

0.49

339

(40760892) CBC W Ordered Manual Differential panel - Blood

334

1.35

0.67

8.6

5.8

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

122

1.48

0.66

2.5

2.3

0.73

1.00

e6/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

228

0.69

0.65

3.0

3.4

—

(40758558) Short blood count panel - Blood

177

1.40

0.63

9.3

6.9

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

495

1.33

0.62

2.9

3.0

—

(3022621) pH of Urine by Test strip

1.62

0.62

3.8

2.5

—

(21494755) Public health laboratory ask at order entry panel

0.54

0.59

1.6

1.3

—

(3013115) Eosinophils [#/volume] in Blood

379

1.31

0.58

10.2

5.6

0.16

0.17

e9/l

0.42

342

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

703

0.75

0.56

4.5

3.8

1.39

1.34

mmol/l

0.22

646

(1761868) Lipid panel - Serum or Plasma

296

0.75

0.55

2.6

2.8

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

109

1.45

0.55

1.7

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

730

0.75

0.54

4.7

4.2

4.70

4.65

mmol/l

0.13

672

(3021601) Nitrite [Presence] in Urine by Test strip

372

1.29

0.54

5.1

5.2

0.00

estimate

—

(3035350) Ketones [Presence] in Urine by Test strip

377

1.26

0.47

3.8

0.00

estimate

—

(3037467) Urinalysis macro (dipstick) panel - Urine

487

1.26

0.46

3.9

4.1

—

(3009261) Glucose [Presence] in Urine by Test strip

379

1.25

0.44

4.0

3.8

0.00

estimate

—

(4200892) Spirometry reversibility

1.47

0.44

1.4

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

244

1.27

0.44

3.7

3.1

550.76

32.87

u/l

0.49

233

(3008898) HLA-B27 [Presence]

1.54

0.42

1.0

1.1

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.41

0.0

1.1

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.41

0.0

1.4

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.41

0.0

1.5

—

(40768800) Prostate Pathology biopsy report

0.00

0.41

0.0

1.1

—

(3045414) Leukocytes [Presence] in Urine

1.50

0.41

3.2

1.7

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.40

0.0

1.4

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.40

0.40

1.9

2.2

—

(3003694) ABO and Rh group [Type] in Blood

200

0.76

0.39

1.7

1.4

—

(3019225) pH of Specimen

1.38

0.39

5.6

4.5

—

(3026008) Bacteria identified in Urine by Culture

201

1.26

0.37

3.3

3.1

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

729

0.79

0.37

4.5

4.2

1.36

1.43

mmol/l

0.81

671

(3030467) Casts [#/volume] in Urine by Automated count

203

1.25

0.34

3.3

2.5

0.04

0.29

e6/l

2.51

145

(3022217) INR in Platelet poor plasma by Coagulation assay

340

1.20

0.32

8.8

12.9

1.06

1.22

inr

1.20

(3012544) pH of Venous blood

1.29

0.31

2.3

3.1

—

(3002256) Pathology report gross observation

1.30

0.28

1.3

1.2

—

(40761511) CBC panel - Blood by Automated count

794

1.28

0.25

16.6

11.9

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

239

1.18

0.25

2.6

2.4

64.15

53.61

u/l

0.50

225

(46235355) HIV 1 and 2 tests - Meaningful Use set

153

1.22

0.24

1.7

2.1

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.27

0.24

2.1

2.3

—

(3009542) Hematocrit [Volume Fraction] of Blood

836

1.38

0.23

26.7

19.3

40.78

40.68

0.07

802

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.33

0.23

3.2

2.5

131.40

127.21

g/l

—

(3022313) Gas panel - Capillary blood

1.30

0.23

3.2

3.0

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

290

1.16

0.22

4.8

3.3

56.98

38.87

ng/l

0.21

199

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.9

—

4.90

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.4

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.21

0.0

3.2

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.2

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.2

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.2

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

6.06

—

(40768795) Lymph node Pathology biopsy report

0.00

0.21

0.0

1.4

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.21

0.0

4.5

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

14.10

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.21

0.0

1.8

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.5

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

2.8

—

107.42

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

2.8

—

3.91

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

2.8

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

1.06

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.2

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.2

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.27

0.21

2.7

2.6

0.02

0.07

e6/l

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

745

0.85

0.20

5.1

4.6

2.80

2.78

mmol/l

0.05

686

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.19

0.20

1.3

2.0

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

1.19

0.20

6.0

3.0

1.67

2.08

mmol/l

—

(4035726) Immunohistochemistry procedure

1.18

0.18

1.4

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

285

1.13

0.17

4.4

4.5

14.50

1.87

ug/l

0.46

255

(3019832) Treponema pallidum Ab [Presence] in Serum

1.14

0.16

1.7

1.8

—

(3000492) Spirometry study

1.21

0.15

1.4

1.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

300

0.90

0.12

4.4

3.9

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

279

0.91

0.11

2.8

1.7

96.79

93.82

pmol/l

0.15

144

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.17

0.10

1.2

1.9

—

(36660697) Celiac disease serology panel - Serum

0.82

0.08

1.4

1.2

—

(3029937) Albumin [Presence] in Urine by Test strip

216

1.09

0.07

4.8

3.8

0.00

0.01

estimate

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

109

1.12

0.06

1.5

1.8

2.45

2.37

g/l

0.22

(3022948) Iron [Moles/volume] in Serum or Plasma

120

1.10

0.05

1.5

1.8

16.72

12.57

umol/l

0.65

110

(40768804) Tissue Pathology biopsy report

292

1.04

0.02

2.4

2.0

—

(3013512) EKG study

207

0.96

0.01

3.7

3.9

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

106

0.94

0.01

1.9

1.8

1.49

1.58

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

665

1.03

0.00

4.3

4.2

1.91

1.89

mu/l

0.02

608

(3007164) IgA [Mass/volume] in Serum or Plasma

156

1.03

0.00

1.3

2.51

2.38

g/l

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

224

0.98

0.00

4.5

4.2

28.57

22.23

—

107

(40768797) Stomach Pathology biopsy report

1.05

0.00

1.3

1.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

131

0.99

0.00

1.7

1.5

—

(3014271) Vancomycin [Susceptibility]

0.00

0.0

1.8

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

72.00

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

0.0

1.4

—

7.74

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(44813793) Dust mix specific IgE antibody measurement

0.00

0.0

1.0

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

3.0

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.99

0.00

7.9

3.5

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

2.8

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

0.0

1.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

1.52

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

8.80

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

1665.20

—

(40760548) Muscle specific receptor tyrosine kinase Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

2.2

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.4

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

9.9

—

1199.00

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

11.3

—

2710.43

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.7

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.97

-0.00

1.4

1.8

322.43

365.47

nmol/l

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

2.1

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

-0.00

0.0

1.4

—

6.41

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

127.36

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.7

—

(3020650) Glucose [Presence] in Urine

0.00

-0.00

0.0

1.2

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.96

-0.00

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.7

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.91

-0.00

1.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.97

-0.00

1.7

1.5

—

(3025941) Bacteria identified in Stool by Culture

1.02

-0.00

1.4

1.2

—

(3023410) Appearance of Cerebral spinal fluid

0.00

-0.00

0.0

1.1

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

3.3

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

-0.00

0.0

1.7

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

3.3

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_CRUSHI_INJURY_LOWER_LEG – Crushing injury of lower leg

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Crushing injury of lower leg

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Crushing injury of lower leg (ST19_CRUSHI_INJURY_LOWER_LEG)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints