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Malignant neoplasm of pyriform sinus, excluding all cancers (controls excluding all cancers)

Endpoint Browser

C3_PIRIFORMSINUS_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — C12&
  • Hospital discharge: ICD-9 — 1481A
  • Hospital discharge: ICD-8 — 1481
  • Cause of death: ICD-10 — C12&
  • Cause of death: ICD-9 — 1481A
  • Cause of death: ICD-8 — 1481
  • Cancer registry: Topography ICD-O-3 — C12
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

3 out of 7 registries used, show all original rules.

49

4. Check minimum number of events

None

49

5. Include endpoints

None

49

6. Filter based on genotype QC (FinnGen only)

49

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

↥

List of similar endpoints to Malignant neoplasm of pyriform sinus, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 49 6 43
Unadjusted period prevalence (%) 0.02 0.00 0.02
Median age at first event (years) 66.93 59.06 68.03

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(4035726)
18
16
17.20
18.18
1.6
1.1
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
17
23
10.79
12.71
2.4
2.0
g/l
0.2
0.2
0.11
17
16
(3044640) Blood type and Crossmatch panel - Blood
28
94
5.62
8.37
4.0
2.0
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
23
72
5.14
7.30
3.9
1.9
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
13
24
7.01
7.21
1.5
1.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
32
137
4.85
6.73
4.8
3.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
24
94
4.04
5.43
3.5
1.6
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
7
5
15.97
4.72
1.4
1.0
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
28
138
3.40
4.25
7.2
3.7
g/l
33.4
34.4
0.42
28
130
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
15
51
3.80
3.99
1.9
1.7
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
10
25
4.77
3.91
1.6
1.6
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
22
99
3.22
3.79
4.5
3.6
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
29
162
2.94
3.31
10.8
10.0
inr
1.1
1.4
—
7
39
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
8
18
5.09
2.94
1.4
1.2
—
—
—
0
0
(3022948) Iron [Moles/volume] in Serum or Plasma
13
50
3.18
2.80
2.6
2.4
umol/l
12.1
13.0
0.20
13
45
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
16
71
2.86
2.70
1.8
1.8
mg/l
3.5
2.8
0.53
11
59
(3022313) Gas panel - Capillary blood
8
21
4.34
2.59
5.0
3.4
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
12
46
3.13
2.58
2.7
2.4
%
19.1
23.7
0.74
12
40
(3006315) Basophils [#/volume] in Blood
27
160
2.53
2.55
6.0
5.4
e9/l
0.0
0.0
0.31
21
131
(3007853) Bacteria identified in Skin by Aerobe culture
10
35
3.33
2.47
1.8
2.2
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
7
17
4.61
2.46
1.6
1.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
17
83
2.61
2.37
1.4
1.2
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
7
18
4.35
2.35
1.6
1.5
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
14
64
2.66
2.20
6.7
2.3
mmol/l
2.5
2.4
0.67
14
56
(3001604) Monocytes [#/volume] in Blood
26
160
2.33
2.17
6.2
5.4
e9/l
0.6
0.6
0.10
21
130
(3013826) Glucose [Moles/volume] in Serum or Plasma
32
216
2.39
2.15
7.7
4.6
mmol/l
6.9
7.2
0.20
32
203
(3018418) pH of Serum or Plasma
18
96
2.38
2.05
3.2
2.9
ph
7.4
7.4
—
5
11
(3013115) Eosinophils [#/volume] in Blood
27
172
2.27
2.04
6.2
5.1
e9/l
0.2
0.2
1.00
22
139
(3002256) Pathology report gross observation
8
27
3.33
2.04
1.9
1.1
—
—
—
0
0
(3027945) Reticulocytes/100 erythrocytes in Blood
10
40
2.88
1.98
2.2
2.8
%
1.7
1.6
—
10
33
(3000991) Gas panel - Venous blood
8
30
2.98
1.82
10.6
7.0
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
6
140
0.35
1.77
4.5
3.2
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
19
114
2.09
1.59
7.1
5.0
—
—
—
0
0
(40758558) Short blood count panel - Blood
13
69
2.20
1.45
11.7
5.3
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
22
148
1.88
1.29
2.1
1.9
pmol/l
82.0
88.8
0.30
15
82
(46235355) HIV 1 and 2 tests - Meaningful Use set
6
26
2.48
1.22
1.5
1.5
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
7
33
2.30
1.11
2.0
1.8
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
7
33
2.30
1.11
2.1
1.6
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
31
240
1.79
1.10
4.1
3.3
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
5
22
2.41
1.06
1.0
1.1
—
—
—
0
0
(3019225) pH of Specimen
7
35
2.16
1.05
13.6
3.2
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
19
129
1.77
1.04
3.2
2.8
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
7
37
2.04
0.98
5.3
2.8
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
21
150
1.70
0.96
10.8
8.1
e9/l
0.0
0.0
0.48
16
115
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
6
31
2.06
0.88
4.7
4.3
umol/l
8.5
9.2
—
6
26
(3023520) Reticulocytes [#/volume] in Blood
6
32
1.99
0.85
3.2
3.2
e9/l
70.1
66.2
—
6
25
(3013512) EKG study
16
110
1.67
0.82
6.7
3.5
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
27
0.00
0.80
0.0
1.5
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
13
85
1.72
0.79
2.5
2.7
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
14
97
1.62
0.68
2.9
2.2
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
7
44
1.69
0.68
1.1
1.5
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
32
366
0.64
0.68
3.5
4.1
mmol/l
1.1
1.3
1.56
27
328
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
5
29
1.80
0.65
6.8
1.6
u/l
28.8
29.2
—
5
21
(3015736) pH of Urine
17
125
1.55
0.65
1.6
3.1
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
33
374
0.64
0.65
3.7
4.7
mmol/l
4.0
4.4
0.98
28
344
(3042936) Bacteria identified in Isolate by Culture
8
52
1.64
0.63
1.5
1.4
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
33
373
0.65
0.63
3.8
4.7
mmol/l
1.4
1.4
0.18
27
337
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
19
0.00
0.62
0.0
1.7
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
16
118
1.53
0.60
1.8
2.2
u/l
81.4
278.5
2.74
16
108
(3000850) Epithelial cells [#/volume] in Urine
11
74
1.63
0.59
2.1
1.9
e6/l
2.7
3.7
0.35
11
59
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
6
40
1.57
0.53
1.5
2.9
ug/l
6.7
12.4
—
6
32
(3026008) Bacteria identified in Urine by Culture
12
85
1.55
0.53
3.7
2.5
—
—
—
0
0
(3022145) Colonoscopy Study observation
5
32
1.62
0.44
1.6
1.3
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
35
380
0.72
0.37
4.4
5.4
mmol/l
2.2
2.6
1.49
28
344
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
24
207
1.31
0.35
5.2
3.6
%
22.8
25.2
0.18
11
101
(40768797) Stomach Pathology biopsy report
6
46
1.35
0.34
1.7
1.2
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
34
365
0.78
0.26
4.9
4.9
mmol/l
5.9
6.3
1.19
29
321
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
24
266
0.81
0.24
5.9
3.8
ug/l
5.6
2.1
0.52
24
239
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
10
80
1.31
0.22
7.1
2.9
ng/l
33.7
207.7
—
10
66
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(4094501)
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(1002224) Polysomnography panel
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
19
169
1.20
0.18
2.4
2.6
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
14
122
1.21
0.16
2.6
3.3
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
30
316
0.87
0.12
32.8
13.4
%
34.3
41.4
1.72
16
215
(3000963) Hemoglobin [Mass/volume] in Blood
39
403
0.84
0.10
44.8
18.1
g/l
126.6
139.9
4.27
39
394
(3044889) 12 lead EKG panel
26
275
0.88
0.10
5.2
4.1
—
—
—
0
0
(3035941) MCH [Entitic mass]
39
402
0.85
0.09
44.1
18.0
pg
31.0
30.8
0.33
39
392
(3024731) MCV [Entitic volume]
39
402
0.85
0.09
44.1
18.1
fl
92.8
91.9
0.49
39
392
(3007461) Platelets [#/volume] in Blood
39
402
0.85
0.09
44.4
18.1
e9/l
231.5
229.5
0.07
39
385
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
18
167
1.12
0.08
3.4
3.5
ng/l
19.5
69.7
1.71
13
125
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
35
361
0.89
0.06
5.7
6.6
mmol/mol
40.0
41.5
0.51
29
326
(3019550) Sodium [Moles/volume] in Serum or Plasma
39
384
1.08
0.01
36.4
15.5
mmol/l
138.0
139.7
2.20
39
368
(3020564) Creatinine [Moles/volume] in Serum or Plasma
39
389
1.01
0.00
36.8
14.8
umol/l
89.3
87.4
0.07
39
389
(40761511) CBC panel - Blood by Automated count
38
377
1.04
0.00
26.2
11.9
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40757494) Bilirubin.total [Moles/volume] in Blood
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
1.1
—
0
6
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
7
70
1.00
0.00
1.6
3.6
—
1.0
—
0
7
(3044290) Cell count panel - Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
8
78
1.03
0.00
1.6
3.2
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3020044) Glucose [Moles/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.4
—
3.8
—
0
7
(3016879) Cocaine [Presence] in Urine
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3039162) Centromere protein B Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
6
0.00
0.00
0.0
4.0
—
35.2
—
0
6
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.4
—
693.0
—
0
8
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
6
60
1.00
0.00
5.0
5.5
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
0.3
—
0
5
(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
9
0.00
0.00
0.0
4.0
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_PIRIFORMSINUS_EXALLC – Malignant neoplasm of pyriform sinus, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).