Malignant neoplasm of hypopharynx, excluding all cancers (controls excluding all cancers)

C3_HYPOPHARYNX_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C12&, C13
  • Hospital discharge: ICD-9 148
  • Hospital discharge: ICD-8 148
  • Cause of death: ICD-10 C12&, C13
  • Cause of death: ICD-9 148
  • Cause of death: ICD-8 148
  • Cancer registry: Topography ICD-O-3 C1[23]
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

239

4. Check minimum number of events

None

239

5. Include endpoints

239

6. Filter based on genotype QC (FinnGen only)

239

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Malignant neoplasm of hypopharynx, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 239 39 200
Unadjusted period prevalence (%) 0.08 0.01 0.09
Median age at first event (years) 67.96 65.14 68.51

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
126
Matched controls
1260
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
110.1
89
*
UJC01
NOMESCO Finland
Scopy of lower throat
491.7
95.0
84
5
JDB10
NOMESCO Finland
Percutaneous gastrostomy
458.6
92.1
82
5
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
382.1
90.9
82
6
8070/3-C13.9
ICD-O-3
Squamous cell carcinoma, NOS, of hypopharynx, NOS
+∞
79.9
68
*
WF002
NOMESCO Finland
Radical radiotherapy
563.4
66.1
60
*
C13.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of hypopharynx
+∞
65.4
57
*
C13.9
ICD-10 Finland
Malignant neoplasm: Hypopharynx, unspecified
+∞
48.0
43
*
A03FA01
ATC
metoclopramide; systemic, rectal
27.4
47.1
69
53
N02AA05
ATC
oxycodone; systemic
18.0
37.9
65
70
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
36.2
33
*
H02AB02
ATC
dexamethasone; systemic
103.3
35.1
37
5
R4190
NOMESCO Finland
Nutritional therapy
119.6
33.7
35
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
63.1
29.1
33
7
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
339.8
27.9
27
*
GBB00
NOMESCO Finland
Tracheostomy
57.8
27.0
31
7
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
25.9
24
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
25.9
24
*
UJC02
NOMESCO Finland
Rigid oesophagoscopy
113.5
25.8
27
*
D10.7
ICD-10 Finland
Benign neoplasm: Hypopharynx
+∞
24.8
23
*
C13.1
ICD-10 Finland
Malignant neoplasm: Aryepiglottic fold, hypopharyngeal aspect
+∞
24.8
23
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
67.9
24.2
27
5
C12
ICD-10 Finland
Malignant neoplasm of piriform sinus
+∞
23.7
22
*
XX3DW
NOMESCO Finland
Time consuming IT work
20.7
22.7
34
22
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
22.6
21
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
263.7
22.3
22
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
12.0
21.7
42
50
C13.2
ICD-10 Finland
Malignant neoplasm: Posterior wall of hypopharynx
+∞
21.5
20
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
29.5
21.1
28
12
A04AA01
ATC
ondansetron; systemic, rectal
69.5
20.7
23
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
6.8
20.5
64
165
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
20.3
19
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
20.3
19
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
20.3
19
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
16.7
19.8
32
25
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
19.2
18
*
WX408
NOMESCO Finland
General anesthesy, balanced
6.2
18.4
62
171
C13.0
ICD-10 Finland
Malignant neoplasm: Postcricoid region
+∞
18.1
17
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
18.1
17
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
110.8
18.1
19
*
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
110.8
18.1
19
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
49.7
17.9
21
5
Z51.5
ICD-10 Finland
Palliative care
23.6
17.7
25
13
WZC30
NOMESCO Finland
Teaching
9.6
17.6
38
54
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
17.1
16
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
9.1
17.0
38
57
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
13.6
16.6
29
27
EBA15
NOMESCO Finland
Extraction of large number of teeth
16.9
16.4
26
19
D37.08
ICD-10 Finland
Tumor of uncertain or unknown nature in other part of lip, oral cavity and pharynx
+∞
16.0
15
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
11.2
15.6
30
34
UDQ22
NOMESCO Finland
Microlaryngoscopy
52.0
15.5
18
*
GD1AD
NOMESCO Finland
Thorax CT examination
15.3
14.1
23
18
8070/3-C12.9
ICD-O-3
Squamous cell carcinoma, NOS, of pyriform sinus
+∞
13.8
13
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
17.7
13.7
21
14
WX402
NOMESCO Finland
General anaesthesia
6.8
13.4
36
70
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
77.9
12.9
14
*
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
+∞
12.7
12
*
8070/3-C13.2
ICD-O-3
Squamous cell carcinoma, NOS, of posterior wall of hypopharynx
+∞
12.7
12
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
12.7
12
*
DQE00
NOMESCO Finland
Implantation of prosthetic replacement for larynx
+∞
12.7
12
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
4.1
12.6
70
294
R13
ICD-10 Finland
Dysphagia
8.5
12.5
28
41
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
7.3
12.4
31
54
WX002
NOMESCO Finland
Sedation and analgesia
4.7
11.8
46
137
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
11.6
11
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
+∞
11.6
11
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
11.6
11
*
ENA10
NOMESCO Finland
Biopsy of pharynx
+∞
11.6
11
*
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
+∞
11.6
11
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
+∞
11.6
11
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
+∞
11.6
11
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
11.6
11
*
UJC12
NOMESCO Finland
Flexible oesophagoscopy
131.4
11.6
12
*
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
11.7
11.5
21
21
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.5
11.2
27
44
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
119.5
10.6
11
*
PJD51
NOMESCO Finland
Block dissection of cervical lymph nodes
+∞
10.6
10
*
A04AD12
ATC
aprepitant; systemic
+∞
10.6
10
*
TGB20
NOMESCO Finland
Tracheostomy tube replacement
+∞
10.6
10
*
TJD20
NOMESCO Finland
Change of gastrostomy tube
35.9
10.5
13
*
A06AD11
ATC
lactulose; oral
4.7
10.5
39
109
WW500
NOMESCO Finland
Blood transfusion
18.7
10.2
15
9
ZXB10
NOMESCO Finland
Medial
59.7
9.8
11
*
DQA10
NOMESCO Finland
Biopsy of larynx
59.7
9.8
11
*
R07.0
ICD-10 Finland
Pain in throat
9.9
9.7
19
22
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
32.8
9.6
12
*
UDQ02
NOMESCO Finland
Direct laryngoscopy
32.8
9.6
12
*
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
107.7
9.5
10
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
107.7
9.5
10
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
9.5
9
*
JN4BD
NOMESCO Finland
Extensive body CT
9.1
9.3
19
24
A07AA02
ATC
nystatin; oral
9.1
9.3
19
24
ZZA00
NOMESCO Finland
Split skin graft
14.0
9.1
15
12
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
96.1
8.5
9
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
8.4
8
*
8070/3-C13.1
ICD-O-3
Squamous cell carcinoma, NOS, of hypopharyngeal aspect of aryepiglottic fold
+∞
8.4
8
*
ENB30
NOMESCO Finland
Laryngopharyngectomy
+∞
8.4
8
*
N06AX11
ATC
mirtazapine; oral
3.3
8.0
49
204
EBA10
NOMESCO Finland
Surgical removal of tooth
5.0
8.0
26
62
N05CF01
ATC
zopiclone; oral
3.0
7.7
55
255
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.9
7.7
34
110
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.1
7.4
51
228
RD210
NOMESCO Finland
NA
17.0
7.4
11
7
JDB00
NOMESCO Finland
Gastrostomy
+∞
7.4
7
*
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
+∞
7.4
7
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
7.4
7
*
C32.1
ICD-10 Finland
Malignant neoplasm: Supraglottis
+∞
7.4
7
*
DQB30
NOMESCO Finland
Laryngectomy
+∞
7.4
7
*
GBB13
NOMESCO Finland
Revision of tracheostomy
+∞
7.4
7
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
7.4
7
*
R4110
NOMESCO Finland
Physiotherapy
3.1
7.1
45
191
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
5.3
7.0
21
46
A02BC05
ATC
esomeprazole; systemic
2.8
6.9
62
325
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
42.4
6.8
8
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
24.0
6.8
9
*
SAA03
NOMESCO Finland
Extended examination of mouth
2.9
6.7
50
234
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
8.9
6.5
13
16
K22.2
ICD-10 Finland
Oesophageal obstruction
19.2
6.4
9
5
ENB00
NOMESCO Finland
Excision or exploration of lesion of pharynx
+∞
6.3
6
*
C32.9
ICD-10 Finland
Malignant neoplasm: Larynx, unspecified
+∞
6.3
6
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
6.3
6
*
Z43.1
ICD-10 Finland
Attention to gastrostomy
+∞
6.3
6
*
D10.9
ICD-10 Finland
Benign neoplasm: Pharynx, unspecified
+∞
6.3
6
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
6.3
6
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
6.2
66
375

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
81
55
21.76
96.00
1.5
1.3
—
—
—
0
0
123
445
4.63
30.80
3.5
1.5
—
—
—
0
0
120
496
3.85
23.57
3.5
2.1
—
—
—
0
0
116
514
3.44
19.67
5.5
2.1
2.3
2.3
mmol/l
0.47
110
424
136
718
3.07
16.28
5.5
3.5
—
—
—
0
0
155
886
3.13
16.00
12.7
5.7
4.7
4.5
e9/l
0.67
138
772
106
496
3.04
15.61
5.7
3.9
—
—
—
0
0
60
206
3.55
14.71
2.1
1.7
—
—
—
0
0
82
351
3.03
13.89
9.6
4.1
—
—
—
0
0
134
747
2.81
13.79
9.2
11.6
1.2
1.4
inr
2.23
37
194
42
118
4.10
13.69
1.5
1.1
—
—
—
0
0
98
469
2.85
13.46
5.6
3.2
7.4
7.4
ph
0.21
23
74
127
723
2.61
12.03
6.8
3.7
32.9
35.3
g/l
4.62
121
663
125
725
2.52
11.13
5.2
5.3
2.9
3.2
%
0.39
114
665
122
703
2.50
10.98
5.2
5.3
0.6
0.7
%
0.41
113
646
99
518
2.56
10.95
5.1
5.4
—
—
—
0
0
125
730
2.49
10.90
5.2
5.5
9.5
9.0
%
0.80
115
668
47
169
3.22
10.49
2.6
2.6
13.8
8.4
umol/l
0.42
42
149
128
772
2.42
10.19
9.1
5.1
1.2
1.2
mmol/l
1.40
122
683
124
740
2.40
10.07
5.3
5.4
21.3
26.1
%
4.49
114
672
133
823
2.39
9.89
10.5
5.6
1.2
1.2
mmol/l
0.78
109
700
123
737
2.38
9.83
5.1
5.3
63.0
58.0
%
3.53
113
676
125
789
2.22
8.44
5.2
5.0
0.0
0.0
e9/l
1.80
104
684
124
783
2.21
8.33
5.3
5.0
0.6
0.6
e9/l
0.51
103
673
115
714
2.18
7.96
11.1
8.0
0.0
0.0
e9/l
0.10
96
592
127
821
2.17
7.91
5.5
5.0
0.2
0.2
e9/l
0.09
106
714
65
319
2.43
7.88
3.9
2.0
2.5
2.4
mmol/l
2.06
60
264
28
87
3.51
7.81
2.4
1.5
2.4
6.3
ug/l
0.61
22
67
124
800
2.14
7.70
5.2
5.0
1.5
1.8
e9/l
4.01
106
696
57
269
2.47
7.49
1.9
1.7
—
—
—
0
0
73
405
2.16
6.49
1.4
1.3
—
—
—
0
0
9
6
15.51
5.95
1.6
2.2
—
—
—
0
0
62
333
2.16
5.93
2.9
2.4
530.9
571.8
mosm/kgh2o
0.68
55
261
139
1731
0.53
5.30
3.3
4.9
1.4
1.4
mmol/l
0.64
123
1570
141
1746
0.53
5.23
3.5
4.9
4.2
4.4
mmol/l
0.65
127
1595
73
443
1.93
4.91
2.8
2.7
—
—
—
0
0
54
296
2.06
4.83
29.4
27.0
1.7
1.3
inr
—
9
37
82
521
1.87
4.78
3.0
2.9
34.2
201.8
e6/l
0.73
71
398
16
50
3.36
4.42
6.6
2.8
7.4
7.4
ph
0.18
11
38
7
6
11.96
4.30
1.0
1.0
—
—
—
0
0
9
13
7.15
4.20
6.3
2.6
—
—
—
0
0
138
1684
0.57
4.18
3.1
4.3
1.2
1.3
mmol/l
1.69
122
1518
74
474
1.81
4.12
2.9
2.7
2.7
0.4
e6/l
0.52
64
345
7
7
10.25
4.03
7.1
1.9
—
—
—
0
0
32
590
0.47
3.91
3.0
3.2
—
—
—
0
0
80
536
1.74
3.78
3.6
2.1
58.3
58.0
u/l
0.01
74
500
15
51
3.07
3.64
5.5
3.0
—
—
—
0
0
68
439
1.77
3.63
2.0
2.0
2.7
2.8
mg/l
0.14
58
365
41
225
1.99
3.62
2.2
2.5
20.6
23.9
%
0.79
35
198
10
26
3.97
3.56
3.7
2.7
60.9
57.7
%
—
10
26
31
156
2.13
3.44
11.2
7.6
—
—
—
0
0
153
1787
0.60
3.38
4.0
5.5
2.4
2.6
mmol/l
1.37
132
1622
142
1686
0.61
3.32
4.4
6.6
38.0
41.2
mmol/mol
4.07
125
1542
85
602
1.64
3.18
3.4
3.4
126.1
80.2
e6/l
0.33
73
428
6
8
7.66
3.07
1.2
1.4
—
—
—
0
0
92
1182
0.64
2.81
3.8
3.8
3.2
2.1
ug/l
0.56
79
1046
11
38
2.99
2.62
5.1
2.7
—
—
—
0
0
7
188
0.35
2.40
1.1
1.5
—
—
—
0
0
34
202
1.80
2.37
1.5
1.6
—
—
—
0
0
31
179
1.84
2.37
2.5
3.6
3.0
1.7
mmol/l
0.49
24
144
7
18
3.97
2.27
1.7
1.2
—
—
—
0
0
38
238
1.71
2.22
11.8
6.1
1.6
1.2
mmol/l
0.29
33
184
62
441
1.55
2.19
2.9
3.0
—
—
—
0
0
8
25
3.27
2.11
4.1
2.0
3.8
4.9
e9/l
—
8
25
20
105
1.99
2.02
12.3
8.5
—
—
—
0
0
48
672
0.64
2.00
3.0
4.2
12.1
9.3
mg/mmol
0.26
31
437
155
1735
0.70
1.86
4.3
4.9
5.9
6.1
mmol/l
3.12
138
1548
8
30
2.72
1.74
5.3
2.7
—
—
—
0
0
13
63
2.12
1.63
1.0
1.1
108.5
103.8
iu/ml
—
6
20
6
20
3.05
1.59
1.3
1.2
—
—
—
0
0
47
629
0.69
1.52
2.5
3.4
2398.0
262.1
mg/l
0.70
33
410
28
180
1.63
1.51
2.7
3.6
6.1
5.8
kpa
0.54
28
174
6
22
2.77
1.44
4.0
1.3
88.3
90.4
%
—
6
22
154
1368
1.35
1.43
35.2
15.3
14.4
13.7
%
4.92
149
1330
52
390
1.43
1.40
1.9
1.8
1364.2
1164.7
nmol/l
0.61
42
301
6
24
2.54
1.31
1.5
1.2
—
—
—
0
0
135
1185
1.32
1.31
5.2
3.2
14.6
15.0
pmol/l
1.15
126
1032
66
816
0.74
1.31
3.5
3.6
0.0
0.0
estimate
0.00
18
121
8
34
2.40
1.30
3.1
2.9
—
—
—
0
0
8
35
2.33
1.28
2.5
2.8
0.9
1.0
nmol/l
—
8
26
6
25
2.43
1.25
4.2
1.4
—
—
—
0
0
65
795
0.75
1.18
3.5
3.6
0.0
0.0
estimate
0.00
17
130
13
72
1.85
1.17
1.2
1.3
1.4
1.5
g/l
0.14
13
60
7
30
2.37
1.13
6.4
1.3
—
—
—
0
0
7
31
2.30
1.11
1.0
1.2
—
—
—
0
0
49
620
0.74
1.11
3.1
3.4
—
—
—
0
0
66
799
0.76
1.10
4.2
4.8
0.0
0.0
estimate
0.00
18
128
31
221
1.46
1.10
12.7
6.3
97.4
94.5
%
4.26
31
214
5
21
2.41
1.09
1.6
1.4
21.2
17.8
u/ml
—
5
21
28
197
1.48
1.06
14.0
6.8
108.3
123.4
g/l
3.34
28
192
141
1268
1.27
1.04
4.9
4.2
—
—
—
0
0
91
776
1.28
1.04
2.1
2.0
84.5
91.3
pmol/l
0.89
55
422
0
29
0.00
0.98
0.0
5.6
—
7.4
—
0
23
180
1911
0.76
0.97
43.6
19.3
7.3
6.8
e9/l
1.93
172
1841
180
1910
0.77
0.96
43.4
19.3
4.1
4.6
e12/l
19.04
171
1839
180
1909
0.77
0.94
43.5
19.3
254.6
232.7
e9/l
3.05
173
1845
54
654
0.77
0.88
2.4
2.6
0.7
0.8
ug/l
0.67
38
438
28
205
1.41
0.88
1.7
1.2
—
—
—
0
0
18
120
1.54
0.88
5.3
3.1
—
—
—
0
0
32
416
0.73
0.86
1.8
1.8
385.6
17169089.0
pmol/l
0.50
27
332
10
165
0.59
0.85
4.2
3.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
77.3
—
0
7
0
25
0.00
0.79
0.0
3.0
—
—
—
0
0
175
1850
0.80
0.78
37.0
15.8
76.7
87.4
umol/l
3.64
175
1850
5
24
2.11
0.75
1.2
2.1
32.6
34.7
pg
—
5
24
5
25
2.02
0.73
2.2
1.1
—
—
—
0
0
16
109
1.50
0.73
4.1
4.0
—
—
—
0
0
11
68
1.65
0.73
1.4
1.5
—
—
—
0
0
5
95
0.52
0.68
2.8
3.2
—
—
—
0
0
75
655
1.21
0.66
3.1
2.5
156.2
159.0
ug/l
0.04
66
588
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
31
381
0.79
0.57
3.1
3.8
—
—
—
0
0
36
433
0.80
0.56
3.5
3.1
—
—
—
0
0
16
116
1.41
0.56
1.4
1.6
—
—
—
0
0
6
37
1.64
0.56
1.2
1.2
—
—
—
0
0
21
161
1.33
0.54
1.4
1.6
—
—
—
0
0
17
126
1.38
0.53
1.4
1.4
—
—
—
0
0
16
118
1.38
0.51
3.4
1.3
—
—
—
0
0
7
110
0.63
0.49
1.0
1.5
—
—
—
0
0
52
592
0.84
0.47
5.1
4.0
—
—
—
0
0
13
94
1.41
0.47
1.1
1.2
—
—
—
0
0
19
147
1.32
0.47
3.1
2.8
4.9
4.4
kpa
0.37
19
140
40
464
0.83
0.44
1.6
1.7
1.1
1.4
mmol/l
1.94
35
384
42
361
1.20
0.44
1.6
1.8
1.2
1.3
mg/l
0.02
32
277
10
70
1.45
0.42
1.5
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.9
—
7.9
—
0
11
0
18
0.00
0.40
0.0
1.1
—
7.6
—
0
10
0
18
0.00
0.40
0.0
1.1
—
2.0
—
0
10
0
18
0.00
0.40
0.0
1.1
—
0.4
—
0
10
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
56
499
1.16
0.40
3.6
2.7
355.1
10026.0
umol/l
2.75
48
440
0
19
0.00
0.39
0.0
1.8
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
328.2
—
0
6
131
1238
1.13
0.39
4.1
3.9
17.4
11.9
mm/h
2.12
119
1114
176
1696
1.14
0.37
32.6
13.2
35.1
26.2
mg/l
3.24
164
1342
174
1799
0.88
0.35
27.6
12.6
—
—
—
0
0
11
144
0.75
0.34
10.6
6.0
26.5
24.0
mmol/l
1.16
11
136
179
1845
0.88
0.33
36.3
16.5
4.0
4.0
mmol/l
1.06
174
1782
10
132
0.75
0.33
1.8
1.5
—
—
—
0
0
6
47
1.28
0.32
2.0
1.1
—
0.2
—
0
5
23
269
0.84
0.29
1.6
1.2
2.8
3.0
g/l
0.11
14
156
40
445
0.88
0.28
4.5
3.8
0.0
0.0
estimate
0.50
17
121
18
151
1.21
0.26
1.5
1.3
—
—
—
0
0
179
1836
0.90
0.26
36.2
16.5
137.6
139.7
mmol/l
10.46
174
1773
9
76
1.19
0.25
2.6
1.8
—
—
—
0
0
9
77
1.18
0.24
1.4
1.2
—
—
—
0
0
18
152
1.20
0.24
6.8
4.1
—
—
—
0
0
10
125
0.79
0.23
2.0
2.9
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
1186.0
—
0
5
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.9
—
0.6
—
0
6
0
13
0.00
0.21
0.0
1.2
—
1.3
—
0
6
0
13
0.00
0.21
0.0
1.1
—
5.5
—
0
6
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
36
327
1.12
0.21
5.5
4.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
25
280
0.88
0.20
1.3
1.2
15.4
1.6
u/ml
—
5
77
15
175
0.85
0.19
8.5
3.2
—
—
—
0
0
11
92
1.21
0.16
1.5
1.3
0.9
1.1
g/l
0.37
11
84
10
83
1.21
0.15
8.9
4.5
1.0
0.9
%
—
10
78
20
223
0.89
0.15
1.2
1.3
1.0
15.4
u/ml
—
5
82
10
85
1.18
0.12
8.9
4.4
2.1
1.7
%
—
10
80
156
1533
1.05
0.11
5.9
4.0
2.8
2.0
mu/l
2.47
147
1352
5
46
1.09
0.09
1.2
2.7
—
—
—
0
0
6
54
1.11
0.09
2.0
1.6
—
—
—
0
0
23
246
0.93
0.08
1.1
1.3
14.6
30.3
iu/ml
—
5
73
8
75
1.07
0.07
2.1
2.4
234.5
998.8
ug/l
—
8
70
13
118
1.11
0.07
2.6
4.3
0.0
0.1
%
—
5
30
117
1150
1.03
0.07
3.9
3.7
—
—
—
0
0
9
103
0.87
0.06
1.4
1.2
—
—
—
0
0
17
159
1.07
0.05
1.5
1.4
—
—
—
0
0
48
467
1.03
0.04
1.8
1.6
18.7
19.9
nmol/l
0.20
42
383
149
1504
0.98
0.04
34.2
14.0
36.1
40.0
%
6.32
107
978
10
92
1.09
0.03
3.6
3.9
—
—
—
0
0
13
124
1.05
0.00
2.6
4.2
0.4
0.8
%
—
5
35
78
786
0.99
0.00
3.7
4.0
30.0
47.1
ng/l
1.01
62
595
10
101
0.99
0.00
1.6
2.4
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
2.8
—
0
8
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
83.3
—
0
7
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
0.2
—
0
9
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
3.3
—
0
6
6
66
0.91
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1.1
—
0
5
0
5
0.00
0.00
0.0
5.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
605.2
—
0
5
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
3.8
—
1.5
—
0
5
0
6
0.00
0.00
0.0
1.3
—
59.0
—
0
6
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
36.6
—
0
5
0
6
0.00
0.00
0.0
6.5
—
—
—
0
0
0
5
0.00
0.00
0.0
6.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
48.4
—
158.0
—
0
7

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_HYPOPHARYNX_EXALLC – Malignant neoplasm of hypopharynx, excluding all cancers (controls excluding all cancers)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).