No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
63 |
4. Check minimum number of eventsNone |
63 |
5. Include endpointsNone |
63 |
6. Filter based on genotype QC (FinnGen only) |
59 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Drug-induced acute pancreatitis
based on the number of shared cases.
Similar with more cases:
- Acute pancreatitis (for exclusion)
- Acute pancreatitis
- Disorders of gallbladder, biliary tract and pancreas
- Gastrointestinal diseases
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 273 | 132 | 141 |
| Only index persons | 265 | 130 | 135 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.01 |
| Median age at first event (years) | |||
| Whole population | - | 50.38 | 50.23 |
| Only index persons | 50.98 | 50.75 | 51.19 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 59 | 28 | 31 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 48.96 | 52.60 | 45.67 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 63
- Matched controls
- 630
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K85.3
ICD-10 Finland
Drug-induced acute pancreatitis
+∞
90.4
63
*
JN3AD
NOMESCO Finland
Abdominal CT examination
9.8
15.7
23
35
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
23.3
15.4
22
14
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
9.0
14.6
23
38
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
29.4
14.4
19
9
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
15.4
14.1
24
24
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.0
12.4
45
166
N02AA05
ATC
oxycodone; systemic
7.1
11.8
23
47
A07EA06
ATC
budesonide; oral, local oral
23.2
11.4
16
9
L01BB02
ATC
mercaptopurine; oral
72.7
11.0
12
*
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
72.7
11.0
12
*
L04AX01
ATC
azathioprine; systemic
17.4
10.9
17
13
UJF32
NOMESCO Finland
Coloscopy
5.5
9.7
26
71
K85.8
ICD-10 Finland
Other acute pancreatitis
58.4
9.0
10
*
K50.8
ICD-10 Finland
Other Crohn disease
58.4
9.0
10
*
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
32.7
8.8
11
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.9
8.8
30
99
UJF30
NOMESCO Finland
Ileoscopy through colon
9.6
8.8
18
25
A07EC02
ATC
mesalazine; oral, rectal
11.9
8.3
15
16
H02AB06
ATC
prednisolone; systemic
4.8
8.1
43
196
R10.1
ICD-10 Finland
Pain localized to upper abdomen
4.8
7.6
23
68
L04AB04
ATC
adalimumab; parenteral
23.3
7.4
10
5
K50.0
ICD-10 Finland
Crohn disease of small intestine
25.8
6.9
9
*
K51.5
ICD-10 Finland
Left sided colitis
14.5
6.9
11
9
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.0
6.5
26
94
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
30.0
6.4
8
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
17.2
6.1
9
6
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
52
188
11.11
15.78
13.9
4.1
33.97
36.39
g/l
1.81
52
179
55
248
10.56
13.01
25.2
6.2
13.85
11.29
umol/l
0.52
55
237
22
22
14.70
12.84
2.1
1.8
—
—
—
0
0
44
173
6.12
10.90
11.0
3.2
48.09
28.24
u/l
0.97
44
160
36
125
5.39
10.18
4.6
2.5
0.31
0.36
e6/l
0.11
29
96
46
199
5.86
9.87
28.0
6.8
1.19
1.21
mmol/l
0.95
39
177
42
175
5.20
9.26
11.8
10.5
1.05
1.17
inr
1.12
11
47
37
153
4.44
7.91
4.8
2.8
—
—
—
0
0
24
74
4.62
7.50
4.4
2.4
1.14
1.23
e6/l
0.06
12
40
15
23
8.20
6.85
1.1
1.3
—
—
—
0
0
22
68
4.43
6.78
4.4
2.8
202.44
1632.88
ng/l
0.48
16
47
20
59
4.50
6.52
44.6
5.1
103.35
103.37
mmol/l
0.01
20
59
20
64
4.11
5.81
5.0
2.5
2.65
2.44
e6/l
—
8
31
12
18
7.95
5.57
2.3
2.2
3.61
14.16
ug/l
0.34
12
18
42
225
3.60
5.54
5.0
2.2
—
—
—
0
0
43
235
3.61
5.47
6.8
3.0
0.00
0.00
estimate
-0.00
11
44
42
233
3.41
5.08
9.8
4.2
0.00
0.00
estimate
-0.00
11
44
42
234
3.38
5.02
7.0
3.0
0.00
0.00
estimate
-0.00
11
43
17
54
3.94
4.92
6.4
2.2
360.24
390.56
nmol/l
0.26
17
48
8
11
8.13
3.99
4.0
1.9
—
—
—
0
0
14
47
3.54
3.68
37.1
2.2
5.85
5.70
kpa
0.17
14
47
24
113
2.82
3.61
6.0
2.0
—
—
—
0
0
11
28
4.53
3.49
3.7
3.7
64.85
66.35
g/l
0.23
11
28
14
49
3.39
3.45
4.1
1.5
—
—
—
0
0
13
40
3.82
3.39
60.2
3.8
1.05
1.55
mmol/l
1.14
13
40
7
11
7.00
3.28
4.7
1.7
—
—
—
0
0
7
11
7.00
3.28
1.0
1.5
—
—
—
0
0
14
51
3.24
3.24
4.4
1.6
—
—
—
0
0
26
134
2.60
3.23
4.6
2.0
113.81
280.36
u/l
0.81
26
128
8
16
5.56
3.16
1.4
1.3
—
—
—
0
0
17
72
2.86
3.05
3.9
1.9
—
—
—
0
0
5
5
10.70
3.03
6.0
1.4
—
—
—
0
0
5
5
10.70
3.03
6.0
1.4
—
—
—
0
0
5
5
10.70
3.03
3.0
2.6
—
—
—
0
0
63
561
+∞
2.81
42.4
9.4
39.57
28.01
u/l
1.54
63
544
63
562
+∞
2.81
54.4
12.1
78.52
73.78
umol/l
0.55
63
562
5
6
8.91
2.80
2.2
1.3
—
—
—
0
0
8
20
4.42
2.67
15.0
3.4
103.13
95.90
%
—
8
20
6
11
5.90
2.60
5.2
1.7
—
—
—
0
0
5
7
7.63
2.59
1.2
1.0
—
—
—
0
0
5
7
7.63
2.59
2.6
1.9
—
—
—
0
0
5
7
7.63
2.59
4.2
1.7
—
—
—
0
0
8
21
4.20
2.56
44.3
5.4
24.68
25.01
mmol/l
—
8
21
30
182
2.24
2.47
6.5
2.8
—
—
—
0
0
8
22
4.01
2.46
59.3
2.0
22.38
25.14
mmol/l
—
8
22
5
8
6.67
2.41
6.0
1.9
—
—
—
0
0
5
8
6.67
2.41
6.0
1.9
—
—
—
0
0
7
18
4.24
2.32
16.4
3.8
206.86
163.67
%
—
7
18
5
9
5.92
2.25
1.2
1.1
—
—
—
0
0
10
38
2.93
2.12
4.2
2.7
—
—
—
0
0
26
158
2.10
2.06
4.7
2.8
18.60
27.16
ng/l
0.43
21
98
5
11
4.83
1.98
2.8
1.7
—
—
—
0
0
7
24
3.15
1.78
7.1
2.4
25.63
24.21
mmol/l
—
7
24
7
25
3.02
1.70
1.4
1.8
—
—
—
0
0
57
495
2.59
1.66
32.8
9.9
91.06
91.37
ml/min/173m2
0.03
51
393
6
21
3.05
1.54
1.7
1.6
—
—
—
0
0
20
122
1.94
1.51
7.6
3.2
0.00
0.00
estimate
—
9
43
7
29
2.59
1.44
109.3
3.7
24.41
24.71
mmol/l
—
7
29
5
18
2.92
1.31
1.2
1.4
0.35
0.23
g/l
—
5
18
24
165
1.73
1.22
3.5
1.8
84.44
94.21
pmol/l
0.96
18
85
5
20
2.62
1.17
1.2
1.4
1.32
1.23
g/l
—
5
20
5
21
2.50
1.11
2.4
1.5
26.38
2.13
mg/l
—
5
14
6
27
2.35
0.96
75.3
2.1
1.52
1.68
%
—
6
27
14
89
1.74
0.91
1.1
1.2
1.17
5.27
u/ml
—
7
39
12
77
1.69
0.75
2.7
2.2
1.47
1.42
%
0.11
12
70
5
25
2.08
0.74
6.4
2.3
—
—
—
0
0
14
95
1.61
0.72
1.5
1.3
7.95
28.26
iu/ml
—
6
32
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
46
425
1.31
0.35
3.6
3.5
—
—
—
0
0
13
107
1.27
0.24
1.6
2.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
10
81
1.28
0.20
3.8
2.3
0.65
0.79
ug/l
—
5
39
6
52
1.17
0.19
2.7
3.9
33.17
30.31
%
—
6
36
10
93
1.09
0.02
1.6
2.3
—
—
—
0
0
14
137
1.03
0.00
1.6
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.85
-0.00
24.8
8.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
13.13
—
0
8
9
90
1.00
-0.00
1.6
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
55
0.90
-0.00
1.6
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint DRUGADVERS_ACUTE_PANCREATIT and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have DRUGADVERS_ACUTE_PANCREATIT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: DRUGADVERS_ACUTE_PANCREATIT – Drug-induced acute pancreatitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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