Adenocarcinoma of small intestine, excluding all cancers (controls excluding all cancers)

C3_SMALL_INTESTINE_ADENO_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C17
  • Cancer registry: Morphology ICD-O-3 8140|8144|8145
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

87

4. Check minimum number of events

None

87

5. Include endpoints

None

87

6. Filter based on genotype QC (FinnGen only)

87

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Adenocarcinoma of small intestine, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 87 37 50
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 68.91 65.83 71.18

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
83
Matched controls
830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
65.5
54
*
8140/3-C17.0
ICD-O-3
Adenocarcinoma, NOS, of duodenum
+∞
42.4
37
*
L01BC06
ATC
capecitabine; oral
+∞
42.4
37
*
C17.0
ICD-10 Finland
Malignant neoplasm: Duodenum
+∞
34.9
31
*
H02AB02
ATC
dexamethasone; systemic
188.0
34.8
34
*
A03FA01
ATC
metoclopramide; systemic, rectal
22.1
29.5
47
46
JFB00
NOMESCO Finland
Partial resection of small intestine
115.1
29.1
30
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
98.2
25.6
27
*
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
+∞
25.3
23
*
A04AA02
ATC
granisetron; systemic, transdermal
331.9
25.1
24
*
JLC30
NOMESCO Finland
Pancreatoduodenectomy
+∞
24.1
22
*
8140/3-C17.9
ICD-O-3
Adenocarcinoma, NOS, of small intestine, NOS
+∞
23.0
21
*
C17.1
ICD-10 Finland
Malignant neoplasm: Jejunum
+∞
23.0
21
*
C17.9
ICD-10 Finland
Malignant neoplasm: Small intestine, unspecified
+∞
21.8
20
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
21.8
20
*
A09AA02
ATC
multienzymes (lipase, protease etc.)
80.8
17.6
19
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
17.3
16
*
C17.2
ICD-10 Finland
Malignant neoplasm: Ileum
+∞
17.3
16
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
23.5
16.9
24
14
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
45.2
15.2
18
5
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
180.5
15.0
15
*
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
22.9
14.8
21
12
A04AA01
ATC
ondansetron; systemic, rectal
52.5
14.8
17
*
JN4AD
NOMESCO Finland
Body CT examination
25.8
14.6
20
10
Z51.5
ICD-10 Finland
Palliative care
32.2
14.1
18
7
8140/3-C17.2
ICD-O-3
Adenocarcinoma, NOS, of ileum
+∞
13.9
13
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
6.1
13.4
50
165
JN4BD
NOMESCO Finland
Extensive body CT
14.0
13.3
23
22
JAH00
NOMESCO Finland
Laparotomy
36.0
12.1
15
5
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
11.7
11
*
8140/3-C17.1
ICD-O-3
Adenocarcinoma, NOS, of jejunum
+∞
11.7
11
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
11.7
11
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
11.3
11.1
21
24
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
10.6
10
*
JN3AD
NOMESCO Finland
Abdominal CT examination
10.0
10.4
21
27
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
20.0
10.3
15
9
N02AA05
ATC
oxycodone; systemic
6.2
10.2
30
69
TPX10
NOMESCO Finland
Implantation of vascular injection port
30.4
10.2
13
5
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
10.2
10.1
20
25
JN3BD
NOMESCO Finland
Extensive abdominal CT
7.6
9.9
24
42
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
41.7
9.3
11
*
B01AB10
ATC
tinzaparin; parenteral
12.1
9.0
16
16
UJF92
NOMESCO Finland
Capsular endoscopy
56.1
8.9
10
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.7
8.9
36
117
C17.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of small intestine
+∞
8.5
8
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.4
8.0
33
107
WX402
NOMESCO Finland
General anaesthesia
5.9
7.6
22
48
UJF32
NOMESCO Finland
Coloscopy
4.1
7.6
37
137
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
87.6
7.5
8
*
Z80.0
ICD-10 Finland
Family history of malignant neoplasm of digestive organs
+∞
7.4
7
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
7.4
7
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
7.4
7
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
7.4
7
*
WW500
NOMESCO Finland
Blood transfusion
22.4
7.3
10
5
R4190
NOMESCO Finland
Nutritional therapy
33.2
7.3
9
*
TPH07
NOMESCO Finland
Cathetrisation of artery
5.8
7.3
21
46
JAH01
NOMESCO Finland
Laparoscopy
15.6
7.1
11
8
A02BC02
ATC
pantoprazole; systemic
3.8
6.9
65
402
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.5
6.7
40
174
R11
ICD-10 Finland
Nausea and vomiting
6.8
6.6
16
28
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
6.3
6
*
K83.1
ICD-10 Finland
Obstruction of bile duct
+∞
6.3
6
*
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
6.3
6
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
6.3
6
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
6.3
6
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
6.3
6
*
JDE00
NOMESCO Finland
Gastrojejunostomy
+∞
6.3
6
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
6.3
6
*
D64.9
ICD-10 Finland
Anaemia, unspecified
4.5
6.1
22
61
TPH04
NOMESCO Finland
Cathetrisation of vein
3.9
6.0
27
92

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(4035726)
27
26
14.61
25.80
1.5
1.2
—
—
—
0
0
(3000570) Elastase.pancreatic [Mass/mass] in Stool
19
15
15.93
20.10
1.6
1.3
ug/g
126.4
315.0
—
14
8
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
64
258
6.60
15.42
8.0
3.5
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
50
177
5.29
13.63
6.4
3.8
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
49
178
5.01
12.75
5.1
2.0
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
62
272
5.45
12.69
14.4
3.4
g/l
32.1
35.5
4.40
62
255
(3012095) Magnesium [Moles/volume] in Serum or Plasma
34
96
5.17
11.95
7.3
2.0
mmol/l
0.8
0.8
0.99
34
84
(40768804) Tissue Pathology biopsy report
47
181
4.47
10.99
3.0
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
14
17
9.62
10.93
2.1
1.8
u/ml
0.3
0.3
—
9
8
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
39
133
4.50
10.67
4.5
2.0
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
34
106
4.62
10.41
1.7
1.3
—
—
—
0
0
(3002256) Pathology report gross observation
21
45
5.83
9.91
1.4
1.1
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
56
285
3.71
8.06
13.4
9.3
inr
1.2
1.3
0.55
14
84
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
10
12
9.29
7.74
1.8
3.3
g/l
3.0
3.5
—
10
12
(3022145) Colonoscopy Study observation
23
72
3.98
6.73
1.7
1.3
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
16
39
4.80
6.41
1.5
1.2
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
58
334
3.21
6.24
10.0
4.5
mmol/l
1.2
1.2
1.78
52
284
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
27
103
3.35
5.84
1.7
1.7
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
11
22
5.58
5.42
13.5
7.7
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
21
72
3.53
5.32
5.9
2.0
u/l
24.4
34.1
1.51
21
58
(3003694) ABO and Rh group [Type] in Blood
29
132
2.80
4.51
1.6
1.2
—
—
—
0
0
(3018418) pH of Serum or Plasma
38
205
2.52
4.16
6.3
3.0
ph
7.4
7.4
—
8
35
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
19
72
3.10
4.05
1.6
1.6
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
31
156
2.53
3.89
1.9
1.9
nmol/l
1457.0
1158.8
0.62
25
117
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
43
252
2.40
3.87
3.7
2.9
—
—
—
0
0
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
6
5
12.74
3.82
1.5
1.2
umol/l
26.3
29.8
—
6
5
(40758558) Short blood count panel - Blood
30
150
2.53
3.80
16.1
4.4
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
13
40
3.65
3.80
1.8
1.3
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
22
95
2.76
3.72
4.0
1.6
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
38
214
2.38
3.71
6.1
4.8
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
18
70
2.98
3.66
5.2
3.0
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
18
73
2.85
3.39
1.7
1.7
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
6
7
9.09
3.31
1.2
4.0
%
234.2
202.9
—
6
7
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
13
44
3.30
3.29
1.6
1.8
—
—
—
0
0
(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma
8
15
5.75
3.27
7.4
1.7
u/ml
46.3
76.4
—
8
15
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
14
50
3.15
3.26
1.4
1.4
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
36
209
2.23
3.18
3.8
2.9
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
8
16
5.39
3.13
1.3
1.7
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
6
8
7.95
3.10
1.2
1.3
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
6
8
7.95
3.10
1.0
1.0
—
—
—
0
0
(3000991) Gas panel - Venous blood
13
46
3.15
3.07
10.0
7.3
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
11
35
3.45
3.05
1.3
1.2
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
5
5
10.49
3.01
3.0
1.8
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
37
223
2.15
2.94
3.8
3.1
e6/l
16.8
340.4
0.59
30
174
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
6
9
7.06
2.91
1.0
1.0
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
8
18
4.78
2.87
1.3
1.1
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
34
200
2.15
2.86
3.9
3.0
e6/l
0.4
0.4
0.06
28
146
(3051611) Lipemic interference index of Serum or Plasma
5
6
8.74
2.78
3.0
2.2
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
12
44
3.00
2.67
1.3
1.6
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
32
189
2.10
2.63
4.1
2.9
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
6
11
5.77
2.59
1.0
1.1
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
5
7
7.49
2.58
1.0
1.6
pmol/l
69.4
76.5
—
5
7
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
23
120
2.25
2.56
3.0
2.7
e6/l
3.9
0.7
1.08
12
61
(3001604) Monocytes [#/volume] in Blood
47
326
1.96
2.43
5.7
4.5
e9/l
0.6
0.6
0.25
41
285
(3005715) Vancomycin [Mass/volume] in Serum or Plasma
5
8
6.54
2.40
4.2
5.6
mg/l
13.8
11.7
—
5
8
(3006315) Basophils [#/volume] in Blood
47
328
1.94
2.37
5.7
4.5
e9/l
0.0
0.0
1.21
41
287
(3013115) Eosinophils [#/volume] in Blood
48
339
1.93
2.32
5.8
4.7
e9/l
0.2
0.2
0.45
41
299
(3018095) Leukocytes [#/volume] in Urine
39
257
1.94
2.32
4.2
3.6
e6/l
1466.5
98.0
0.46
30
185
(3007853) Bacteria identified in Skin by Aerobe culture
18
89
2.29
2.26
1.4
1.7
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
47
332
1.90
2.25
5.7
4.7
e9/l
1.5
1.8
1.34
41
294
(3018677) aPTT in Platelet poor plasma by Coagulation assay
20
104
2.20
2.23
2.1
1.7
s
29.6
29.8
0.09
20
97
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
8
25
3.42
2.15
1.8
1.7
—
—
—
0
0
(3012544) pH of Venous blood
15
71
2.34
2.06
6.2
3.9
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
16
79
2.26
2.01
1.4
1.6
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
9
33
2.92
2.00
1.3
1.3
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
23
135
1.96
1.86
3.7
3.6
—
—
—
0
0
(3019060) Gas panel - Arterial blood
11
47
2.53
1.86
10.3
3.5
—
—
—
0
0
(3020891) Body temperature
8
29
2.93
1.84
8.5
3.5
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
43
310
1.77
1.82
2.8
2.0
pmol/l
89.2
93.9
0.26
26
153
(3015736) pH of Urine
37
257
1.77
1.76
6.1
3.5
—
—
—
0
0
(40761535) Cells panel - Urine sediment
11
49
2.43
1.72
3.3
2.9
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
6
19
3.31
1.69
5.2
1.7
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
59
686
0.57
1.59
4.0
5.7
mmol/l
2.5
2.6
0.31
51
631
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
24
151
1.81
1.56
4.6
3.4
ng/l
140.6
112.4
0.09
19
122
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
55
650
0.58
1.55
3.6
4.5
mmol/l
1.1
1.3
1.69
47
589
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
20
119
1.88
1.55
3.1
2.9
e6/l
3.0
2.4
—
9
62
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
58
676
0.57
1.54
3.8
5.1
mmol/l
4.2
4.5
0.99
51
625
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
6
21
2.99
1.53
1.8
1.7
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
6
23
2.72
1.39
3.8
2.7
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
58
670
0.60
1.37
3.7
5.0
mmol/l
1.3
1.5
2.48
51
614
(3021589) Normoblasts [#/volume] in Blood
39
293
1.60
1.31
24.8
7.8
e9/l
0.0
0.0
0.47
32
232
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
8
38
2.21
1.22
5.0
2.2
%
0.6
0.6
—
8
38
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
8
39
2.16
1.19
5.0
2.2
%
0.9
1.2
—
8
39
(3021601) Nitrite [Presence] in Urine by Test strip
42
331
1.52
1.10
9.2
5.1
estimate
0.0
0.0
—
10
59
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
54
623
0.65
1.09
5.1
4.7
mu/l
2.0
1.9
0.02
49
562
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
30
0.00
0.99
0.0
1.6
—
—
—
0
0
(3019225) pH of Specimen
11
63
1.85
0.95
2.7
2.9
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
42
339
1.46
0.94
6.4
3.7
estimate
0.0
0.1
—
9
54
(3035350) Ketones [Presence] in Urine by Test strip
41
332
1.44
0.89
6.6
3.6
estimate
0.0
0.0
—
10
57
(1761868) Lipid panel - Serum or Plasma
16
226
0.64
0.81
3.0
3.5
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
22
160
1.50
0.81
2.2
1.9
pmol/l
378.3
435.5
0.62
16
125
(3037467) Urinalysis macro (dipstick) panel - Urine
54
466
1.42
0.80
7.5
4.2
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
23
173
1.45
0.72
6.0
3.9
estimate
0.0
0.0
—
10
57
(3045414) Leukocytes [Presence] in Urine
5
26
1.98
0.72
2.2
1.9
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
12
78
1.62
0.70
15.7
7.9
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
5
27
1.90
0.69
1.0
1.3
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
5
27
1.90
0.69
1.0
1.3
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
5
27
1.90
0.69
1.0
1.3
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
7
43
1.68
0.68
10.1
3.4
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
8
52
1.59
0.61
5.5
3.1
—
—
—
0
0
(3016921) Smith extractable nuclear Ab [Units/volume] in Serum
0
20
0.00
0.61
0.0
1.4
—
3.9
—
0
5
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
0
22
0.00
0.60
0.0
1.5
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
22
0.00
0.60
0.0
1.6
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
6
35
1.77
0.59
1.0
1.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
39
332
1.32
0.57
2.6
2.4
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
9
64
1.45
0.53
1.3
1.3
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
30
253
1.28
0.45
7.9
3.8
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
25
298
0.77
0.45
4.6
4.0
ug/l
1.8
1.9
0.05
18
270
(3022621) pH of Urine by Test strip
8
55
1.50
0.44
2.6
2.4
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
5
31
1.65
0.44
1.0
1.1
—
28.9
—
0
7
(3020682) Albumin/Creatinine [Ratio] in Urine
21
255
0.77
0.43
4.5
4.1
mg/mmol
19.5
5.7
0.43
15
160
(3007164) IgA [Mass/volume] in Serum or Plasma
16
124
1.36
0.42
1.4
1.3
g/l
2.7
3.0
—
10
66
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
17
0.00
0.41
0.0
1.3
—
45.0
—
0
17
(3012516) Albumin [Mass/volume] in Urine
20
243
0.77
0.41
3.4
3.1
mg/l
103.7
297.8
0.33
14
159
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
22
183
1.27
0.36
7.4
3.5
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
19
155
1.29
0.36
5.1
3.5
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
35
308
1.23
0.36
4.9
3.8
ng/l
21.9
57.1
1.97
26
229
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
10
74
1.40
0.34
1.8
2.6
ug/l
5.8
5.6
—
10
64
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
19
224
0.81
0.30
3.9
3.8
%
24.2
24.7
—
8
102
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
64
673
0.81
0.30
4.4
5.0
mmol/l
6.1
6.1
0.06
59
610
(46235355) HIV 1 and 2 tests - Meaningful Use set
8
65
1.25
0.28
1.4
1.5
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
68
706
0.83
0.23
57.4
15.6
umol/l
79.2
82.4
0.24
68
706
(3044889) 12 lead EKG panel
53
500
1.15
0.21
6.1
4.0
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
11
0.00
0.21
0.0
3.6
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
6
50
1.21
0.20
1.5
1.3
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
6
51
1.19
0.20
1.3
1.2
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
55
523
1.14
0.18
4.5
4.3
mm/h
22.3
12.9
2.08
49
478
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
18
158
1.18
0.18
2.3
2.8
ug/l
0.9
0.8
—
9
112
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
62
640
0.89
0.13
46.0
12.5
ml/min/173m2
78.5
74.0
0.84
57
523
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
5
45
1.12
0.10
4.6
3.4
kpa
5.2
5.0
—
5
36
(3009542) Hematocrit [Volume Fraction] of Blood
58
583
0.98
0.00
48.1
13.9
%
33.8
40.0
3.22
33
394
(40761511) CBC panel - Blood by Automated count
68
684
0.97
0.00
49.6
12.2
—
—
—
0
0
(3013512) EKG study
23
229
1.01
0.00
5.7
4.1
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
51
506
1.02
0.00
4.2
3.8
pmol/l
14.9
14.9
0.10
45
448
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
5
0.00
0.00
0.0
1.4
—
114.0
—
0
5
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000012) Reticulocyte production index
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(21494434) Karyotype in Bone marrow
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4062490)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3006442) Creatine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3023323) Follitropin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
47.9
—
0
5
(3035637) Corticotropin [Mass/volume] in Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3016724) Homocysteine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.0
—
23.0
—
0
5
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
15.4
—
0
5
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3011951) Aspergillus fumigatus IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
0.1
—
0
5
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(4268621)
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
6
59
1.02
0.00
1.0
1.4
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3051593) INR in Capillary blood by Coagulation assay
0
6
0.00
0.00
0.0
11.2
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(44806420)
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
6
0.00
0.00
0.0
2.3
—
10.3
—
0
6
(3028300) Cannabinoids [Presence] in Urine
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
5
53
0.94
0.00
1.8
1.2
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_SMALL_INTESTINE_ADENO_EXALLC – Adenocarcinoma of small intestine, excluding all cancers (controls excluding all cancers)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).